mk 0663 has been researched along with dabrafenib in 1 studies
| Studies (mk 0663) | Trials (mk 0663) | Recent Studies (post-2010) (mk 0663) | Studies (dabrafenib) | Trials (dabrafenib) | Recent Studies (post-2010) (dabrafenib) |
|---|---|---|---|---|---|
| 549 | 173 | 265 | 825 | 107 | 808 |
| Protein | Taxonomy | mk 0663 (IC50) | dabrafenib (IC50) |
|---|---|---|---|
| Receptor-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | 0.077 | |
| GTPase KRas | Homo sapiens (human) | 5.88 | |
| RAF proto-oncogene serine/threonine-protein kinase | Homo sapiens (human) | 0.15 | |
| Serine/threonine-protein kinase A-Raf | Homo sapiens (human) | 0.026 | |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | 0.0033 | |
| TGF-beta receptor type-1 | Homo sapiens (human) | 3.7 | |
| Receptor-interacting serine/threonine-protein kinase 3 | Homo sapiens (human) | 0.126 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Becker, A; Dömkes, S; Hillen, U; Livingstone, E; Schadendorf, D; Zimmer, L | 1 |
1 trial(s) available for mk 0663 and dabrafenib
| Article | Year |
|---|---|
Panniculitis with arthralgia in patients with melanoma treated with selective BRAF inhibitors and its management.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Arthralgia; Disease Progression; Dose-Response Relationship, Drug; Drug Eruptions; Etoricoxib; Female; Humans; Imidazoles; Indoles; Lymphatic Metastasis; Melanoma; Middle Aged; Neoplasm Staging; Oximes; Panniculitis; Point Mutation; Proto-Oncogene Proteins B-raf; Pyridines; Skin Neoplasms; Sulfonamides; Sulfones; Vemurafenib | 2012 |