Page last updated: 2024-09-03

mk 0663 and arachidonic acid

mk 0663 has been researched along with arachidonic acid in 3 studies

Compound Research Comparison

Studies
(mk 0663)
Trials
(mk 0663)
Recent Studies (post-2010)
(mk 0663)
Studies
(arachidonic acid)
Trials
(arachidonic acid)
Recent Studies (post-2010) (arachidonic acid)
54917326519,2954863,040

Protein Interaction Comparison

ProteinTaxonomymk 0663 (IC50)arachidonic acid (IC50)
60 kDa heat shock protein, mitochondrialHomo sapiens (human)4.5
Fatty acid-binding protein, adipocyteHomo sapiens (human)2.75
10 kDa heat shock protein, mitochondrialHomo sapiens (human)4.5
60 kDa chaperonin Escherichia coli7.3
10 kDa chaperonin Escherichia coli7.3
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)1.0715
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)0.6026

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Boyce, S; Brideau, C; Chan, CC; Charleson, S; Dubé, D; Ethier, D; Falgueyret, JP; Ford-Hutchinson, AW; Friesen, RW; Girard, Y; Gordon, R; Greig, G; Gresser, M; Guay, J; Mancini, J; Ouellet, M; Percival, MD; Prasit, P; Riendeau, D; Rodger, IW; Visco, D; Wong, E; Xu, L; Young, RN; Zamboni, R1
Angioni, C; Felden, L; Ferreiros, N; Geisslinger, G; Lötsch, J; Schreiber, Y; von Hentig, N; Walter, C1
Gorbach, T; Koiro, O; Kudina, O; Shtrygol, S; Tovchiga, O; Yudkevich, T1

Trials

1 trial(s) available for mk 0663 and arachidonic acid

ArticleYear
Similar maximum systemic but not local cyclooxygenase-2 inhibition by 50 mg lumiracoxib and 90 mg etoricoxib: a randomized controlled trial in healthy subjects.
    Pharmaceutical research, 2014, Volume: 31, Issue:7

    Topics: Adult; Arachidonic Acid; Cross-Over Studies; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Double-Blind Method; Etoricoxib; Humans; Male; Prostaglandins; Pyridines; Sulfones; Young Adult

2014

Other Studies

2 other study(ies) available for mk 0663 and arachidonic acid

ArticleYear
Etoricoxib (MK-0663): preclinical profile and comparison with other agents that selectively inhibit cyclooxygenase-2.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:2

    Topics: Algorithms; Animals; Anti-Inflammatory Agents; Arachidonic Acid; CHO Cells; Cricetinae; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Etoricoxib; Gastrointestinal Diseases; Humans; Ionophores; Isoenzymes; Male; Membrane Proteins; Microsomes, Liver; Prostaglandin-Endoperoxide Synthases; Pyridines; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Substrate Specificity; Sulfones; Thromboxane B2

2001
The effect of non-steroidal anti-inflammatory drugs with different mechanisms of action on the body temperature and cyclooxygenase pathway of the arachidonic acid cascade on the model of acute general cooling (air hypothermia) in rats.
    Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti, 2022,Fall, Volume: 71, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Body Temperature; Cyclooxygenase 2; Diclofenac; Dinoprost; Dinoprostone; Etoricoxib; Hypothermia; Rats

2022