Compounds > mk 0663
Page last updated: 2024-09-03

mk 0663 and allopurinol

mk 0663 has been researched along with allopurinol in 3 studies

Compound Research Comparison

Studies
(mk 0663)		Trials
(mk 0663)		Recent Studies (post-2010)
(mk 0663)		Studies
(allopurinol)		Trials
(allopurinol)		Recent Studies (post-2010) (allopurinol)
54917326515,0967433,363

Protein Interaction Comparison

ProteinTaxonomymk 0663 (IC50)allopurinol (IC50)
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase Rattus norvegicus (Norway rat)3.3765
Xanthine dehydrogenase/oxidaseHomo sapiens (human)3.1861
Xanthine dehydrogenase/oxidaseBos taurus (cattle)5.0758
Histamine H3 receptorCavia porcellus (domestic guinea pig)8.69

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Fokter, SK; Repse-Fokter, A1

Other Studies

3 other study(ies) available for mk 0663 and allopurinol

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Acute gouty arthritis in a patient after total knee arthroplasty.
    Wiener klinische Wochenschrift, 2010, Volume: 122, Issue:11-12

    Topics: Acute Disease; Aged; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Arthroplasty, Replacement, Knee; Diagnosis, Differential; Drug Therapy, Combination; Etoricoxib; Follow-Up Studies; Gout Suppressants; Humans; Male; Osteoarthritis, Knee; Postoperative Complications; Pyridines; Sulfones

2010