mk 0591 has been researched along with leukotriene e4 in 7 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 6 (85.71) | 18.2507 |
2000's | 1 (14.29) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Arruda, JM; Baccei, C; Bain, G; Chapman, C; Correa, L; Darlington, J; Evans, JF; Hutchinson, JH; King, CD; Lee, C; Li, Y; Lorrain, D; Prasit, P; Prodanovich, P; Rong, H; Santini, A; Stock, N | 1 |
Bajwa, K; Becker, AB; Black, C; Ford-Hutchinson, AW; Lilley, MK; Simons, FE; Tagari, P | 1 |
Black, C; Ellis, R; Ford-Hutchinson, A; Lane, CG; O'Byrne, PM; Stevens, WH; Tagari, P; Woolley, MJ | 1 |
Black, C; Brideau, C; Chan, C; Ford-Hutchinson, A; Frenette, R; Tagari, P | 1 |
Becker, A; Brideau, C; Ford-Hutchinson, A; Frenette, R; Sadl, V; Tagari, P; Thomas, E; Vickers, P | 1 |
Friedman, BS; Hara, K; Kanamaru, M; Kosuge, K; Nakashima, M; Takenaga, N; Tanaka, W; Uchiyama, N; Uematsu, T | 1 |
De Lepeleire, I; De Schepper, PJ; Depré, M; Larson, P; Lin, C; Porras, A; Schwartz, J; Van Hecken, A; Verbesselt, R | 1 |
2 trial(s) available for mk 0591 and leukotriene e4
Article | Year |
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Pharmacokinetic and pharmacodynamic analysis of a novel leukotriene biosynthesis inhibitor, MK-0591, in healthy volunteers.
Topics: Administration, Oral; Adult; Dose-Response Relationship, Drug; Double-Blind Method; Eating; Fasting; Humans; Indoles; Japan; Leukotriene B4; Leukotriene E4; Lipoxygenase Inhibitors; Male; Middle Aged; Quinolines | 1995 |
Pharmacokinetic and pharmacodynamic interaction between the lipoxygenase inhibitor MK-0591 and the cyclooxygenase inhibitor ibuprofen in man.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Digestive System; Double-Blind Method; Drug Interactions; Drug Tolerance; Humans; Ibuprofen; Indoles; Kidney; Leukotriene B4; Leukotriene E4; Lipoxygenase Inhibitors; Male; Quinolines; Thromboxane B2 | 1998 |
5 other study(ies) available for mk 0591 and leukotriene e4
Article | Year |
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5-lipoxygenase-activating protein inhibitors: development of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid (AM103).
Topics: 5-Lipoxygenase-Activating Proteins; Animals; Asthma; Carrier Proteins; Dogs; Drug-Related Side Effects and Adverse Reactions; Heterocyclic Compounds; Humans; Indoles; Inhibitory Concentration 50; Leukotriene B4; Membrane Proteins; Mice; Propionates; Protein Binding; Rats; Structure-Activity Relationship | 2009 |
Antiasthmatic effects of a leukotriene biosynthesis inhibitor (MK-0591) in allergic dogs.
Topics: 5-Lipoxygenase-Activating Proteins; Airway Resistance; Allergens; Animals; Asthma; Bronchoalveolar Lavage Fluid; Carrier Proteins; Dogs; Histamine; Indoles; Leukotriene Antagonists; Leukotriene B4; Leukotriene E4; Leukotrienes; Membrane Proteins; Quinolines; Respiratory Hypersensitivity | 1995 |
Effect of FLAP antagonist MK-0591 on leukotriene production and ozone-induced airway responses in dogs.
Topics: 5-Lipoxygenase-Activating Proteins; Acetylcholine; Airway Resistance; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Carrier Proteins; Dogs; Indoles; Inflammation; Leukotriene Antagonists; Leukotriene B4; Leukotriene E4; Leukotrienes; Lipoxygenase Inhibitors; Membrane Proteins; Ozone; Quinolines; Respiratory System | 1994 |
Assessment of the in vivo biochemical efficacy of orally active leukotriene biosynthesis inhibitors.
Topics: Animals; Calcimycin; Chromatography, High Pressure Liquid; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotriene E4; Leukotrienes; Lipoxygenase Inhibitors; Male; Quinolines | 1993 |
Leukotriene generation and metabolism in dogs: inhibition of biosynthesis by MK-0591.
Topics: 5-Lipoxygenase-Activating Proteins; Animals; Asthma; Carrier Proteins; Disease Models, Animal; Dogs; Indoles; Leukotriene Antagonists; Leukotriene E4; Leukotrienes; Membrane Proteins; Quinolines; SRS-A | 1993 |