mk 0591 has been researched along with arachidonic acid in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Borgeat, P; Laviolette, M; Ménard, L | 1 |
| Charleson, S; Evans, JF; Léger, S; Perrier, H; Prasit, P; Vickers, PJ; Wang, Z | 1 |
| Borgeat, P; Marleau, S; Odeimat, A; Palmantier, R; Poubelle, PE; Surette, ME | 1 |
| Borgeat, P; Krump, E; Picard, S; Surette, ME | 1 |
| Borgeat, P; Bourgoin, SG; Flamand, N; Grenier, S; Naccache, PH; Pelletier, J | 1 |
| Becker, JW; Chu, L; Cunningham, BR; Evans, JF; Ferguson, AD; McKeever, BM; Miller, DK; Spencer, RH; Ujjainwalla, F; Wisniewski, D; Xu, S; Yamin, TT | 1 |
6 other study(ies) available for mk 0591 and arachidonic acid
| Article | Year |
|---|---|
Studies of the inhibitory activity of MK-0591 (3-[1-(4-chlorobenzyl)-3-(t-butylthio)-5-(quinolin-2-yl-methoxy)-indol- 2-yl]-2,2-dimethyl propanoic acid) on arachidonic acid metabolism in human phagocytes.
Topics: Adult; Arachidonic Acid; Calcimycin; Depression, Chemical; Eosinophils; Humans; Indoles; Leukotrienes; Macrophages, Alveolar; Male; Monocytes; Neutrophils; Phagocytes; Quinolines | 1992 |
Structural requirements for the binding of fatty acids to 5-lipoxygenase-activating protein.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5-Lipoxygenase-Activating Proteins; Arachidonic Acid; Binding Sites; Carrier Proteins; Humans; Hydroxyeicosatetraenoic Acids; Indoles; Leukocytes; Leukotrienes; Membrane Proteins; Quinolines; Radioligand Assay | 1994 |
Reverse-phase high-performance liquid chromatography analysis of arachidonic acid metabolites in plasma after stimulation of whole blood ex vivo.
Topics: Aged; Animals; Anticoagulants; Arachidonic Acid; Calcimycin; Chromatography, High Pressure Liquid; Eosinophils; Female; Humans; Indoles; Kinetics; Leukotriene Antagonists; Leukotriene B4; Middle Aged; Quinolines; Rabbits; Spectrophotometry, Ultraviolet; Stimulation, Chemical; Synovial Fluid; Time Factors; Zymosan | 1994 |
Activation of leukotriene synthesis in human neutrophils by exogenous arachidonic acid: inhibition by adenosine A(2a) receptor agonists and crucial role of autocrine activation by leukotriene B(4).
Topics: Adenosine; Adrenergic Agonists; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Autocrine Communication; Benzopyrans; Biological Transport; Biotransformation; Calcium; Carboxylic Acids; Cell Nucleus; Eicosapentaenoic Acid; Epoxide Hydrolases; Humans; In Vitro Techniques; Indoles; Kinetics; Leukotriene Antagonists; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Neutrophil Activation; Neutrophils; Phenethylamines; Purinergic P1 Receptor Agonists; Quinolines; Receptor, Adenosine A2A; Receptors, Leukotriene B4 | 1999 |
Arachidonic acid activates phospholipase D in human neutrophils; essential role of endogenous leukotriene B4 and inhibition by adenosine A2A receptor engagement.
Topics: ADP-Ribosylation Factor 1; Arachidonic Acid; Autocrine Communication; Benzopyrans; beta-Alanine; Biological Transport; Carboxylic Acids; Cell Membrane; Eicosapentaenoic Acid; Enzyme Activation; Epoxide Hydrolases; Humans; Indoles; Leukotriene Antagonists; Leukotriene B4; Lipoxygenase Inhibitors; Neutrophils; Phospholipase D; Protein Transport; Purinergic P1 Receptor Antagonists; Quinolines; Receptor, Adenosine A2A; Receptors, Leukotriene B4; Receptors, Purinergic P1; rhoA GTP-Binding Protein | 2003 |
Crystal structure of inhibitor-bound human 5-lipoxygenase-activating protein.
Topics: 5-Lipoxygenase-Activating Proteins; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Binding Sites; Carrier Proteins; Catalytic Domain; Crystallography, X-Ray; Cytosol; Humans; Hydrophobic and Hydrophilic Interactions; Indoles; Membrane Proteins; Models, Molecular; Mutagenesis; Nuclear Envelope; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Quinolines | 2007 |