mitragynine--(3beta-16e-20beta)-isomer has been researched along with mitragynine* in 3 studies
3 other study(ies) available for mitragynine--(3beta-16e-20beta)-isomer and mitragynine
| Article | Year |
|---|---|
Activity of
Kratom alkaloids have mostly been evaluated for their opioid activity but less at other targets that could contribute to their physiological effects. Here, we investigated the in vitro and in vivo activity of kratom alkaloids at serotonin receptors (5-HTRs). Paynantheine and speciogynine exhibited high affinity for 5-HT Topics: Analgesics; Animals; Behavior, Animal; Female; HEK293 Cells; Humans; Male; Nociceptive Pain; Rats, Sprague-Dawley; Receptors, Serotonin; Secologanin Tryptamine Alkaloids | 2021 |
Pharmacokinetics of Eleven Kratom Alkaloids Following an Oral Dose of Either Traditional or Commercial Kratom Products in Rats.
Kratom, Topics: Alkaloids; Animals; Indole Alkaloids; Indoles; Male; Mitragyna; Molecular Structure; Oxindoles; Plant Preparations; Rats; Rats, Sprague-Dawley; Secologanin Tryptamine Alkaloids; Spiro Compounds | 2021 |
Investigation of the Adrenergic and Opioid Binding Affinities, Metabolic Stability, Plasma Protein Binding Properties, and Functional Effects of Selected Indole-Based Kratom Alkaloids.
Selected indole-based kratom alkaloids were evaluated for their opioid and adrenergic receptor binding and functional effects, in vivo antinociceptive effects, plasma protein binding, and metabolic stability. Mitragynine, the major alkaloid in Topics: Adrenergic Agents; Analgesics; Animals; Blood Proteins; CHO Cells; Cricetulus; Dopamine Agents; Guinea Pigs; Humans; Microsomes, Liver; Rats; Receptors, Adrenergic; Receptors, Opioid; Secologanin Tryptamine Alkaloids | 2020 |