mitoxantrone has been researched along with razoxane in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (46.15) | 18.2507 |
| 2000's | 6 (46.15) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Alderton, PM; Green, MD; Gross, J | 1 |
| Dorr, RT; Shipp, NG | 1 |
| Armand, JP; de Forni, M | 1 |
| Hasinoff, BB; Malisza, KL | 1 |
| Alberts, DS; Dawson, BV; Dorr, RT; Hendrix, M; Shipp, NG | 1 |
| Lemez, P; Maresová, J | 1 |
| Boland, MP; Fitzgerald, KA; O'Neill, LA | 1 |
| Budman, DR; Calabro, A; Kreis, W | 1 |
| Chadwick, DP; Chai, J; Ferrans, VJ; Hasinoff, BB; Herman, EH; Knapton, A; Lipshultz, SE; Rifai, N; Zhang, J | 1 |
| Chan, A; Gold, R; Toyka, KV; Weilbach, FX | 1 |
| Bernitsas, E; Mikol, DD; Wei, W | 1 |
| Jensen, PB; Langer, SW; Sehested, M; Thougaard, AV | 1 |
1 review(s) available for mitoxantrone and razoxane
| Article | Year |
|---|---|
Cardiotoxicity of chemotherapy.
Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophosphamide; Fluorouracil; Heart Diseases; Humans; Mice; Mitoxantrone; Neoplasms; Paclitaxel; Prospective Studies; Rabbits; Rats; Razoxane | 1994 |
2 trial(s) available for mitoxantrone and razoxane
| Article | Year |
|---|---|
Efficacy of dexrazoxane as a cardioprotective agent in patients receiving mitoxantrone- and daunorubicin-based chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cardiovascular Agents; Daunorubicin; Female; Heart Diseases; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Razoxane | 1998 |
Suppression of mitoxantrone cardiotoxicity in multiple sclerosis patients by dexrazoxane.
Topics: Adult; Animals; Antineoplastic Agents; Cardiovascular Agents; Female; Heart Failure; Humans; Male; Middle Aged; Mitoxantrone; Multiple Sclerosis; Razoxane; Stroke Volume; Troponin I | 2006 |
10 other study(ies) available for mitoxantrone and razoxane
| Article | Year |
|---|---|
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Comparative study of doxorubicin, mitoxantrone, and epirubicin in combination with ICRF-187 (ADR-529) in a chronic cardiotoxicity animal model.
Topics: Animals; Doxorubicin; Epirubicin; Female; Heart; Mice; Mice, Inbred BALB C; Mitoxantrone; Myocardium; Premedication; Random Allocation; Razoxane | 1992 |
Biochemical effects and toxicity of mitoxantrone in cultured heart cells.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Heart; Lipid Peroxidation; Malondialdehyde; Mitoxantrone; Myocardium; Razoxane | 1991 |
Doxorubicin reduces the iron(III) complexes of the hydrolysis products of the antioxidant cardioprotective agent dexrazoxane (ICRF-187) and produces hydroxyl radicals.
Topics: Aerobiosis; Antibiotics, Antineoplastic; Antioxidants; Chelating Agents; Doxorubicin; Electron Spin Resonance Spectroscopy; Ethylenediamines; Ferric Compounds; Ferrous Compounds; Glycine; Heart; Hydrolysis; Hydroxyl Radical; Mitoxantrone; Models, Chemical; Oxidation-Reduction; Razoxane | 1995 |
Characterization of experimental mitoxantrone cardiotoxicity and its partial inhibition by ICRF-187 in cultured neonatal rat heart cells.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Heart Diseases; Humans; Leukemia, Experimental; Male; Mice; Mice, Inbred DBA; Microscopy, Electron; Mitoxantrone; Multiple Myeloma; Myocardium; Rats; Rats, Sprague-Dawley; Razoxane; Sensitivity and Specificity; Tumor Cells, Cultured | 1993 |
Topoisomerase II is required for mitoxantrone to signal nuclear factor kappa B activation in HL60 cells.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Line; DNA Damage; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enzyme Activation; HL-60 Cells; Humans; Isoenzymes; Mitoxantrone; NF-kappa B; Protein Isoforms; Razoxane; Thiobarbiturates; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2000 |
In vitro effects of dexrazoxane (Zinecard) and classical acute leukemia therapy: time to consider expanded clinical trials?
Topics: Acute Disease; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cell Death; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Humans; Inhibitory Concentration 50; Leukemia; Mitoxantrone; Razoxane; Tumor Cells, Cultured | 2001 |
The use of serum levels of cardiac troponin T to compare the protective activity of dexrazoxane against doxorubicin- and mitoxantrone-induced cardiotoxicity.
Topics: Animals; Antineoplastic Agents; Biomarkers; Cardiovascular Agents; Doxorubicin; Heart; Infusions, Intravenous; Male; Mitoxantrone; Myocardium; Rats; Rats, Inbred SHR; Razoxane; Troponin T | 2001 |
The cardioprotector dexrazoxane augments therapeutic efficacy of mitoxantrone in experimental autoimmune encephalomyelitis.
Topics: Animals; Apoptosis; Cardiotonic Agents; Chelating Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Encephalomyelitis, Autoimmune, Experimental; Female; Gelatinases; Immunosuppressive Agents; Lymph Nodes; Lymphocyte Activation; Macrophages; Mitoxantrone; Rats; Rats, Inbred Lew; Razoxane; Spinal Cord; T-Lymphocytes | 2004 |
Treatment of experimental extravasation of amrubicin, liposomal doxorubicin, and mitoxantrone with dexrazoxane.
Topics: Animals; Anthracyclines; Antineoplastic Agents; Disease Models, Animal; Doxorubicin; Extravasation of Diagnostic and Therapeutic Materials; Female; Humans; Mice; Mitoxantrone; Razoxane; Treatment Outcome | 2012 |