mitoxantrone and nadp
mitoxantrone has been researched along with nadp in 10 studies
Research
Studies (10)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (80.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Fisher, GR; Gutierrez, PL; Oldcorne, MA; Patterson, LH | 1 |
| Brown, JR; Fisher, GR; Patterson, LH | 1 |
| Basra, J; Brown, JR; Patterson, LH; Wolf, CR | 1 |
| Kharasch, ED; Novak, RF | 3 |
| Davies, KJ; Doroshow, JH | 1 |
| Kharasch, ED; Novak, RF; Wendel, NK | 1 |
| Bachur, NR; Bernstein, AL; Dodion, P; Fox, BM | 1 |
| Korytowska, A; Kostrzewa-Nowak, D; Paine, MJ; Piotrowska, S; Serwatka, K; Tarasiuk, J; Wolf, CR | 1 |
Other Studies
10 other study(ies) available for mitoxantrone and nadp
| Article | Year |
|---|---|
NAD(P)H (quinone acceptor) oxidoreductase (DT-diaphorase)-mediated two-electron reduction of anthraquinone-based antitumour agents and generation of hydroxyl radicals.
Topics: Animals; Anthraquinones; Antineoplastic Agents; Daunorubicin; Dose-Response Relationship, Drug; Hydroxides; Hydroxyl Radical; Kinetics; Liver; Mitoxantrone; NAD(P)H Dehydrogenase (Quinone); NADP; Oxidation-Reduction; Rats; Structure-Activity Relationship; Superoxides | 1992 |
Redox cycling in MCF-7 human breast cancer cells by antitumor agents based on mitozantrone.
Topics: Breast Neoplasms; Cell Survival; Free Radicals; Humans; Mitoxantrone; NADP; Oxidation-Reduction; Superoxides; Tumor Cells, Cultured | 1989 |
Evidence for human liver mediated free-radical formation by doxorubicin and mitozantrone.
Topics: Doxorubicin; Free Radicals; Humans; Microsomes, Liver; Mitoxantrone; NADP; Oxidation-Reduction; Superoxides | 1985 |
Mitoxantrone: propensity for free radical formation and lipid peroxidation--implications for cardiotoxicity.
Topics: Animals; Anthraquinones; Daunorubicin; Doxorubicin; Free Radicals; Heart; Hydrogen Peroxide; Lipid Peroxides; Mitoxantrone; Myocardium; NADP; Rabbits; Subcellular Fractions; Superoxides | 1985 |
Redox cycling of anthracyclines by cardiac mitochondria. II. Formation of superoxide anion, hydrogen peroxide, and hydroxyl radical.
Topics: Animals; Anthraquinones; Antibiotics, Antineoplastic; Cattle; Chemical Phenomena; Chemistry; Daunorubicin; Doxorubicin; Electron Spin Resonance Spectroscopy; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Methane; Mitochondria, Heart; Mitomycin; Mitomycins; Mitoxantrone; NAD; NADP; Naphthacenes; Oxidation-Reduction; Oxygen Consumption; Rotenone; Superoxides | 1986 |
Anthracenedione antineoplastic agent effects on drug metabolism in vitro and in vivo: relationship between structure and mechanism of inhibition.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Male; Mitoxantrone; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Oxygenases; Pharmaceutical Preparations; Rabbits; Structure-Activity Relationship | 1987 |
Loss of fluorescence by anthracycline antibiotics: effects of xanthine oxidase and identification of the nonfluorescent metabolites.
Topics: Anaerobiosis; Animals; Anthracyclines; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Daunorubicin; Doxorubicin; Kinetics; Liver; Male; Mitoxantrone; NAD; NADP; Naphthacenes; Rats; Rats, Inbred Strains; Xanthine Oxidase | 1987 |
Anthracenedione activation by NADPH-cytochrome P-450 reductase; comparison with anthracyclines.
Topics: Animals; Anthracenes; Anthraquinones; Antibiotics, Antineoplastic; Antineoplastic Agents; Cytochrome Reductases; Daunorubicin; Doxorubicin; Kinetics; Microsomes, Liver; Mitoxantrone; NADH Dehydrogenase; NADP; Naphthacenes; Rabbits; Superoxides | 1981 |
Inhibition of microsomal oxidative drug metabolism by 1,4-bis (2-[(2-hydroxyethyl)amino]-ethylamino)-9,10-anthracenedione diacetate, a new antineoplastic agent.
Topics: Animals; Anthraquinones; Antineoplastic Agents; Chemical Phenomena; Chemistry; Male; Microsomes, Liver; Mitoxantrone; Mixed Function Oxygenases; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Pharmaceutical Preparations; Rabbits | 1982 |
Bioreductive activation of mitoxantrone by NADPH cytochrome P450 reductase. Implications for increasing its ability to inhibit the growth of sensitive and multidrug resistant leukaemia HL60 cells.
Topics: Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Spectrophotometry | 2007 |