mitotane and su 11248

mitotane has been researched along with su 11248 in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's6 (85.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bang, SM; Kim, CJ; Kim, H; Kim, JH; Kim, JS; Kim, YJ; Lee, HE; Lee, JO; Lee, JS; Lee, KW1
Gelderblom, H; Guchelaar, HJ; Hartigh, Jd; Ploeger, BA; Romijn, JA; van Erp, NP1
Allolio, B; Fassnacht, M; Kroiss, M; Lutz, WK; Quinkler, M1
Allolio, B; Fassnacht, M; Hahner, S; Johanssen, S; Kroiss, M; Lankheet, N; Laubner, K; Müller, HH; Pöllinger, A; Quinkler, M; Strasburger, CJ; van Erp, NP1
Chen, Y; Qiu, S; Tu, X; Wang, D; Wu, R; Zhuang, J1

Reviews

2 review(s) available for mitotane and su 11248

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drug interactions with mitotane by induction of CYP3A4 metabolism in the clinical management of adrenocortical carcinoma.
    Clinical endocrinology, 2011, Volume: 75, Issue:5

    Topics: Adrenocortical Carcinoma; Animals; Antineoplastic Agents; Cytochrome P-450 CYP3A; Drug Interactions; Humans; Indoles; Mitotane; Pyrroles; Sunitinib

2011

Trials

2 trial(s) available for mitotane and su 11248

ArticleYear
Mitotane has a strong and a durable inducing effect on CYP3A4 activity.
    European journal of endocrinology, 2011, Volume: 164, Issue:4

    Topics: Adrenocortical Carcinoma; Adult; Aged; Antineoplastic Agents; Cytochrome P-450 CYP3A; Enzyme Activation; Female; Humans; Indoles; Male; Middle Aged; Mitotane; Pyrroles; Sunitinib

2011
Sunitinib in refractory adrenocortical carcinoma: a phase II, single-arm, open-label trial.
    The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:10

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Disease Progression; Drug Interactions; Drug Resistance, Neoplasm; Female; Humans; Indoles; Male; Middle Aged; Mitotane; Pyrroles; Sunitinib; Treatment Outcome; Young Adult

2012

Other Studies

3 other study(ies) available for mitotane and su 11248

ArticleYear
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Metastatic adrenocortical carcinoma treated with sunitinib: a case report.
    Japanese journal of clinical oncology, 2009, Volume: 39, Issue:3

    Topics: Adrenal Cortex Neoplasms; Angiogenesis Inhibitors; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Drug Resistance, Neoplasm; Humans; Indoles; Male; Mitotane; Pyrroles; Radiotherapy, Adjuvant; Sunitinib; Treatment Failure; Treatment Outcome; Young Adult

2009
Sunitinib monotherapy instead of mitotane combination therapy for the treatment of refractory adrenocortical carcinoma.
    International journal of urology : official journal of the Japanese Urological Association, 2015, Volume: 22, Issue:11

    Topics: Adrenocortical Carcinoma; Adult; Antineoplastic Agents; Chemotherapy, Adjuvant; Female; Humans; Indoles; Lung Neoplasms; Mitotane; Multiple Pulmonary Nodules; Nephrectomy; Pyrroles; Sunitinib; Tomography, X-Ray Computed

2015