Compounds > mitotane

mitotane and spironolactone

mitotane has been researched along with spironolactone in 12 studies

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (33.33)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (33.33)	29.6817
2010's	3 (25.00)	24.3611
2020's	1 (8.33)	2.80

Authors

Authors	Studies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Soler, NG; Wortsman, J	1
Courtois, H; Schrub, JC	1
Bennett, AH; Dluhy, RG; Newmark, SR	1
Elias, AN; Gwinup, G	1
Boushey, RP; Dackiw, AP	1
Shibata, H	1
Billalabeitia, EG; Carmona-Bayonas, A; Díaz, MP; Gómez, FI; Saura, HP; Soler, IO; Tafalla, MS	1
Hu, S; Infantino, D; Lubitz, S; Ohri, A; Sedhom, R	1
Haberbosch, L; Jumpertz von Schwartzenberg, R; Mai, K; Maurer, L; Sandforth, A; Spranger, J; Wernicke, C	1

Reviews

4 review(s) available for mitotane and spironolactone

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Effects of some clinically encountered drugs on steroid synthesis and degradation. Metabolism: clinical and experimental, 1980, Volume: 29, Issue:6 Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Drug Interactions; Ethanol; Fetus; Gonadal Steroid Hormones; Gonadotropins, Pituitary; Humans; Hydrocortisone; Hydroxycholecalciferols; Liver; Metyrapone; Mitotane; Phenobarbital; Phenytoin; Rifampin; Spironolactone; Steroids	1980
Adrenal cortical carcinoma. Current treatment options in oncology, 2001, Volume: 2, Issue:4 Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Algorithms; Antineoplastic Agents; Carcinoma; Chemotherapy, Adjuvant; Child, Preschool; Combined Modality Therapy; Cushing Syndrome; Epidemiologic Methods; Female; Humans; Hyperaldosteronism; Incidence; Male; Middle Aged; Mineralocorticoids; Mitotane; Spironolactone; Steroids; Treatment Outcome	2001
[Deoxycorticosterone-producing adrenal tumor]. Nihon rinsho. Japanese journal of clinical medicine, 2006, May-28, Volume: Suppl 1 Topics: Adrenal Gland Neoplasms; Adrenalectomy; Antineoplastic Agents, Hormonal; Desoxycorticosterone; Diagnosis, Differential; Humans; Hypertension; Hyponatremia; Mineralocorticoid Receptor Antagonists; Mitotane; Prognosis; Renin; Spironolactone	2006

Other Studies

8 other study(ies) available for mitotane and spironolactone

Article	Year
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Mitotane. Spironolactone antagonism in Cushing's syndrome. JAMA, 1977, Dec-05, Volume: 238, Issue:23 Topics: Aged; Cushing Syndrome; Diarrhea; Female; Humans; Hypokalemia; Mitotane; Nausea; Spironolactone	1977
[Letter: Idiopathic hemochromatosis and Cushing's disease]. La Nouvelle presse medicale, 1975, Mar-29, Volume: 4, Issue:13 Topics: Adrenocortical Hyperfunction; Adult; Cushing Syndrome; Female; Hemochromatosis; Humans; Mitotane; Spironolactone	1975
Ectopic adrenocorticotropin syndrome with prostatic carcinoma. Urology, 1973, Volume: 2, Issue:6 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenocarcinoma; Adrenocorticotropic Hormone; Blood Glucose; Dexamethasone; Humans; Male; Metyrapone; Middle Aged; Mitotane; Neoplasm Metastasis; Paraneoplastic Endocrine Syndromes; Potassium; Prostatic Neoplasms; Psychotic Disorders; Spironolactone	1973
Tailored hormonal therapy in secretory adrenocortical cancer. Annals of oncology : official journal of the European Society for Medical Oncology, 2007, Volume: 18, Issue:7 Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Aged; Aldosterone; Alkalosis; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents; Antifungal Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Captopril; Cisplatin; Diarrhea; Doxorubicin; Etoposide; Female; Heart Failure; Humans; Hydrocortisone; Hyperaldosteronism; Hypertension; Hypokalemia; Ketoconazole; Mineralocorticoid Receptor Antagonists; Mitotane; Neoplasm Recurrence, Local; Potassium; Rhabdomyolysis; Spironolactone; Tachycardia	2007
Symptomatic Cushing's syndrome and hyperandrogenemia in a steroid cell ovarian neoplasm: a case report. Journal of medical case reports, 2016, Oct-12, Volume: 10, Issue:1 Topics: Aged; Antineoplastic Agents, Hormonal; Cushing Syndrome; Disease Progression; Fatal Outcome; Female; Humans; Hyperandrogenism; Ketoconazole; Mitotane; Ovarian Neoplasms; Practice Guidelines as Topic; Rare Diseases; Sex Cord-Gonadal Stromal Tumors; Spironolactone	2016
Spironolactone is associated with reduced mitotane levels in adrenocortical carcinoma patients. Endocrine-related cancer, 2022, 02-03, Volume: 29, Issue:3 Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Antineoplastic Agents, Hormonal; Humans; Male; Middle Aged; Mitotane; Retrospective Studies; Spironolactone	2022