mitotane and metyrapone

mitotane has been researched along with metyrapone in 49 studies

Research

Studies (49)

Timeframe	Studies, this research(%)	All Research%
pre-1990	20 (40.82)	18.7374
1990's	8 (16.33)	18.2507
2000's	4 (8.16)	29.6817
2010's	13 (26.53)	24.3611
2020's	4 (8.16)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Besser, GM; Jeffcoate, WJ	1
Barnes, AJ; Cassar, J; Joplin, GF; Kelly, WF; Loizou, S; Mashiter, K; Welbourn, RB; White, M	1
Brooks, MH; Lawrence, AM; Paloyan, E; Prinz, RA	1
deAsis, DN; Samaan, NA	1
Besser, GM; Howlett, TA; Rees, LH	1
Takeda, R	1
Brandt, I; Klasson-Wehler, E; Lund, BO	1
Carey, RM; Hartmann, WH; Orth, DN	1
Schein, PS	1
Meng, S; Meng, W	1
Raith, L	1
Yamada, S	1
Bennett, AH; Dluhy, RG; Newmark, SR	1
Doret, AM; Paunier, L; Riondel, AM; Sizonenko, PC	1
Plager, JE	1
Boscaro, M; Dal Bo Zanon, R; Fabris, F; Fornasiero, L; Girolami, A; Luzzato, G; Ruffato, G	1
Elias, AN; Gwinup, G	1
Bergstrand, CG; Nilsson, KO	1
Krieger, DT	1
Bricaire, H; Luton, JP	1
Crapo, L; Miller, JW	1
Freeman, DA	1
Bruyette, DS; Myers, NC	1
Engelhardt, D	1
Nishikawa, T; Saito, J	1
Jönsson, CJ; Lund, BO	1
Girard, F; Raux-Demay, MC	1
Corley, PA	1
Ito, N; Morishita, K; Okumura, H; Takahashi, N	1
Dang, CN; Trainer, P	1
Bertagna, X; Bertherat, J; Biller, BM; Boscaro, M; Buchfelder, M; Colao, A; Grossman, AB; Hermus, AR; Hofland, LJ; Klibanski, A; Lacroix, A; Lindsay, JR; Melmed, S; Newell-Price, J; Nieman, LK; Petersenn, S; Sonino, N; Stalla, GK; Stewart, PM; Swearingen, B; Vance, ML; Wass, JA	1
Dluhy, RG; Jain, SH; Nosé, V; Sadow, PM	1
Alexandraki, KI; Grossman, AB	1
de Herder, WW; Feelders, RA; Hofland, LJ	1
Baudin, E; Blanchard, A; Brailly-Tabard, S; Chanson, P; Droumaguet, C; Gautier, JF; Jublanc, C; Kamenický, P; Leboulleux, S; Salenave, S; Schlumberger, M; Young, J	1
Biller, BM; Tritos, NA	1
Barahona Constanzo, MJ; del Pozo Picó, C	1
Gadelha, MR; Vieira Neto, L	1
Daniel, E; Newell-Price, JD	1
Berruti, A; Cerri, S; Claps, M; Ferrari, V; Grisanti, S; Lazzari, B; Perotti, P; Roca, E; Sigala, S; Terzolo, M	1
Berruti, A; De Francia, S; Germano, A; Perotti, P; Rapa, I; Saba, L; Terzolo, M; Volante, M	1
Biller, BMK; Tritos, NA	1
Braun, LT; Reincke, M	1
Tritos, NA	1
Boguszewski, CL; Marques, JVO	1
Hull, B; Wedrychowicz, A	1

Reviews

24 review(s) available for mitotane and metyrapone

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Cushing's syndrome. Clinics in endocrinology and metabolism, 1985, Volume: 14, Issue:4 Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Alcoholism; Bromocriptine; Circadian Rhythm; Corticotropin-Releasing Hormone; Cushing Syndrome; Cyproheptadine; Depression; Dexamethasone; Female; Gonadotropin-Releasing Hormone; Humans; Hydrocortisone; Insulin; Male; Metyrapone; Mitotane; Pituitary Gland; Potassium; Prognosis; Prolactin; Thyrotropin-Releasing Hormone; Time Factors; Tomography, X-Ray Computed	1985
[Clinical studies on a disorder of mineralocorticoid metabolism]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1986, Volume: 75, Issue:2 Topics: Aldosterone; Humans; Hyperaldosteronism; Kanamycin; Ketoconazole; Metyrapone; Mineralocorticoids; Mitotane; Mixed Function Oxygenases	1986
Chemotherapeutic management of the hormone-secreting endocrine malignancies. Cancer, 1972, Volume: 30, Issue:6 Topics: Adenoma, Islet Cell; Adrenal Gland Neoplasms; Aminoglutethimide; Aniline Compounds; Antibiotics, Antineoplastic; Antineoplastic Agents; Butanones; Carcinoid Tumor; Diazoxide; Humans; Hypoglycemia; Insulin Antagonists; Kidney Tubules; Metyrapone; Mitotane; Neoplasm Metastasis; Pheochromocytoma; Pyrimidines; Pyrroles; Pyrrolidines; Ribonucleosides; Serotonin Antagonists; Streptozocin	1972
Effects of some clinically encountered drugs on steroid synthesis and degradation. Metabolism: clinical and experimental, 1980, Volume: 29, Issue:6 Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Drug Interactions; Ethanol; Fetus; Gonadal Steroid Hormones; Gonadotropins, Pituitary; Humans; Hydrocortisone; Hydroxycholecalciferols; Liver; Metyrapone; Mitotane; Phenobarbital; Phenytoin; Rifampin; Spironolactone; Steroids	1980
Treatment of Cushing's disease in children. Acta paediatrica Scandinavica, 1982, Volume: 71, Issue:1 Topics: Adrenalectomy; Adrenocorticotropic Hormone; Aminoglutethimide; Bromocriptine; Child; Cushing Syndrome; Cyproheptadine; Dihydrotestosterone; Female; Humans; Metyrapone; Mitotane; Pituitary Gland; Valproic Acid	1982
Pathophysiology and treatment of Cushing's disease. Progress in clinical and biological research, 1982, Volume: 87 Topics: Adrenal Glands; Adrenalectomy; Aminoglutethimide; Cushing Syndrome; Delayed-Action Preparations; Humans; Hypothalamus; Metyrapone; Mitotane; Pituitary Gland	1982
The medical treatment of Cushing's syndrome. Endocrine reviews, 1993, Volume: 14, Issue:4 Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Aminoglutethimide; Animals; Bromocriptine; Cushing Syndrome; Cyproheptadine; Dogs; Horses; Humans; Ketoconazole; Metyrapone; Mifepristone; Mitotane; Octreotide; Palliative Care; Pituitary Gland; Radiography; Valproic Acid	1993
Feline adrenocortical diseases: Part I--Hyperadrenocorticism. Seminars in veterinary medicine and surgery (small animal), 1994, Volume: 9, Issue:3 Topics: Adrenocorticotropic Hormone; Animals; Cat Diseases; Cats; Cushing Syndrome; Dexamethasone; Diagnosis, Differential; Dogs; Humans; Ketoconazole; Metyrapone; Mitotane; Tomography, X-Ray Computed	1994
Steroid biosynthesis inhibitors in Cushing's syndrome. The Clinical investigator, 1994, Volume: 72, Issue:7 Topics: Adrenal Cortex Hormones; Aminoglutethimide; Cushing Syndrome; Dihydrotestosterone; Etomidate; Humans; Ketoconazole; Metyrapone; Mitotane	1994
[Clinical usefulness of pharmacological treatment of Cushing's syndrome]. Nihon rinsho. Japanese journal of clinical medicine, 1994, Volume: 52, Issue:3 Topics: Administration, Oral; Aminoglutethimide; Cushing Syndrome; Dihydrotestosterone; Humans; Ketoconazole; Metyrapone; Mitotane	1994
[Cushing syndrome in children]. Annales de pediatrie, 1993, Volume: 40, Issue:7 Topics: Adolescent; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Adult; beta-Lipotropin; Child; Child, Preschool; Clinical Protocols; Combined Modality Therapy; Corticotropin-Releasing Hormone; Cushing Syndrome; Dexamethasone; Female; Growth Disorders; Humans; Magnetic Resonance Imaging; Male; Metyrapone; Mitotane; Nelson Syndrome; Obesity; Postoperative Complications	1993
Treatment of adrenocorticotropin-dependent Cushing's syndrome: a consensus statement. The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:7 Topics: ACTH Syndrome, Ectopic; Adrenal Insufficiency; Adrenalectomy; Adrenocorticotropic Hormone; Cushing Syndrome; Humans; Hypophysectomy; Metyrapone; Mitotane; Nelson Syndrome	2008
Medical therapy of Cushing's disease: where are we now? Frontiers of hormone research, 2010, Volume: 38 Topics: Dopamine Agonists; Humans; Hydrocortisone; Ketoconazole; Metyrapone; Mifepristone; Mitotane; Pituitary ACTH Hypersecretion; Somatostatin	2010
Medical treatment of Cushing's syndrome: adrenal-blocking drugs and ketaconazole. Neuroendocrinology, 2010, Volume: 92 Suppl 1 Topics: Cushing Syndrome; Enzyme Inhibitors; Etomidate; Humans; Ketoconazole; Metyrapone; Mitotane	2010
Advances in medical therapies for Cushing's syndrome. Discovery medicine, 2012, Volume: 13, Issue:69 Topics: Animals; Bexarotene; Cushing Syndrome; Etomidate; Humans; Ketoconazole; Lapatinib; Metyrapone; Mifepristone; Mitotane; Quinazolines; Somatostatin; Tetrahydronaphthalenes	2012
New prospects for drug treatment in Cushing disease. Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2012, Volume: 59, Issue:10 Topics: Adenoma; Adrenocorticotropic Hormone; Animals; Cabergoline; Clinical Trials as Topic; Clinical Trials, Phase III as Topic; Drug Evaluation, Preclinical; Ergolines; Etomidate; Humans; Hydrocortisone; Imidazoles; Ketoconazole; Metyrapone; Mice; Mifepristone; Mitotane; Multicenter Studies as Topic; Pituitary ACTH Hypersecretion; Pituitary Neoplasms; PPAR gamma; Pyridines; Rats; Somatostatin; Therapies, Investigational; Tretinoin	2012
Efficacy of medical treatment in Cushing's disease: a systematic review. Clinical endocrinology, 2014, Volume: 80, Issue:1 Topics: Cabergoline; Ergolines; Female; Humans; Ketoconazole; Male; Metyrapone; Mitotane; Pituitary ACTH Hypersecretion; Somatostatin	2014
Therapy of endocrine disease: steroidogenesis enzyme inhibitors in Cushing's syndrome. European journal of endocrinology, 2015, Volume: 172, Issue:6 Topics: Cushing Syndrome; Etomidate; Humans; Imidazoles; Ketoconazole; Metyrapone; Mitotane; Pyridines; Steroid Synthesis Inhibitors	2015
Medical Management of Cushing Disease. Neurosurgery clinics of North America, 2019, Volume: 30, Issue:4 Topics: Cabergoline; Etomidate; Humans; Ketoconazole; Metyrapone; Mitotane; Pituitary ACTH Hypersecretion; Somatostatin; Temozolomide; Treatment Outcome	2019
What is the role of medical therapy in adrenal-dependent Cushing's syndrome? Best practice & research. Clinical endocrinology & metabolism, 2020, Volume: 34, Issue:3 Topics: Adrenal Gland Diseases; Cushing Syndrome; Humans; Ketoconazole; Metyrapone; Mitotane; Pituitary ACTH Hypersecretion; Prospective Studies; Treatment Outcome	2020
Adrenally Directed Medical Therapies for Cushing Syndrome. The Journal of clinical endocrinology and metabolism, 2021, 01-01, Volume: 106, Issue:1 Topics: Adrenal Glands; Cushing Syndrome; Etomidate; Humans; Imidazoles; Ketoconazole; Metyrapone; Mitotane; Molecular Targeted Therapy; Pyridines	2021
Medical therapy in severe hypercortisolism. Best practice & research. Clinical endocrinology & metabolism, 2021, Volume: 35, Issue:2 Topics: Cabergoline; Cushing Syndrome; Humans; Ketoconazole; Metyrapone; Mitotane	2021
The function of adrenal glands in children and adolescents during and after oncological treatment. Pediatric endocrinology, diabetes, and metabolism, 2022, Volume: 28, Issue:3 Topics: Adolescent; Adrenal Glands; Child; Etomidate; Fluconazole; Humans; Hypothalamo-Hypophyseal System; Immune Checkpoint Inhibitors; Ketoconazole; Metyrapone; Mitotane; Pituitary-Adrenal System; Quality of Life	2022

Other Studies

25 other study(ies) available for mitotane and metyrapone

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Endocrine and metabolic diseases. Adrenal diseases. British medical journal, 1976, Feb-21, Volume: 1, Issue:6007 Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Insufficiency; Adrenal Medulla; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Carcinoma; Cushing Syndrome; Female; Humans; Hyperaldosteronism; Hyperplasia; Male; Metyrapone; Mitotane; Pheochromocytoma	1976
Cushing's syndrome due to adrenocortical carcinoma - a comphrensive clinical and biochemical study of patients treated by surgery and chemotherapy. Acta endocrinologica, 1979, Volume: 91, Issue:2 Topics: 17-Ketosteroids; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Carcinoma; Cortodoxone; Cushing Syndrome; Desoxycorticosterone; Electrolytes; Estradiol; Female; Humans; Hydrocortisone; Luteinizing Hormone; Metyrapone; Middle Aged; Mitotane; Pregnanetriol; Testosterone	1979
The continued importance of adrenalectomy in the treatment of Cushing's disease. Archives of surgery (Chicago, Ill. : 1960), 1979, Volume: 114, Issue:4 Topics: Adolescent; Adrenalectomy; Adult; Cushing Syndrome; Cyproheptadine; Female; Humans; Hypophysectomy; Male; Metyrapone; Middle Aged; Mitotane; Phenytoin; Radiotherapy	1979
Feminizing adrenocortical carcinoma with Cushing's syndrome and pseudohyperparathyroidism. Archives of internal medicine, 1978, Volume: 138, Issue:2 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adult; Aminoglutethimide; Androstenedione; Cushing Syndrome; Dexamethasone; Estrogens; Feminization; Humans; Hyperparathyroidism; Male; Metyrapone; Mitotane; Paraneoplastic Endocrine Syndromes; Parathyroid Hormone; Testosterone	1978
o,p'-DDD in the mouse lung: selective uptake, covalent binding and effect on drug metabolism. Chemico-biological interactions, 1986, Volume: 60, Issue:2 Topics: Adipose Tissue; Adrenal Glands; Aminopyrine; Animals; Autoradiography; Benzoflavones; beta-Naphthoflavone; DDT; Dose-Response Relationship, Drug; Isomerism; Liver; Lung; Maleates; Metyrapone; Mice; Mice, Inbred C57BL; Mitotane; Phenobarbital; Pulmonary Alveoli	1986
Malignant melanoma with ectopic production of adrenocorticotropic hormone. Palliative treatment with inhibitors of adrenal steroid biosynthesis. The Journal of clinical endocrinology and metabolism, 1973, Volume: 36, Issue:3 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aminoglutethimide; Cushing Syndrome; Female; Hormones, Ectopic; Humans; Hydrocortisone; Melanoma; Metyrapone; Middle Aged; Mitotane; Neoplasm Metastasis; Palliative Care	1973
[Diagnosis and therapy of endogenic hypercortisolism (Cushing's syndrome)]. Zeitschrift fur arztliche Fortbildung, 1972, Oct-15, Volume: 66, Issue:20 Topics: Adrenalectomy; Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Dexamethasone; Diagnosis, Differential; Female; Humans; Hydrocortisone; Metyrapone; Mitotane	1972
[Medical therapy of hyperadrenalism]. Minerva medica, 1973, Mar-14, Volume: 64, Issue:14 Topics: Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aminoglutethimide; Cushing Syndrome; Humans; Metyrapone; Mitotane	1973
[Urinary 6beta-hydroxycortisol. II. Urinary 6beta-hydroxycortisol in different diseases and after administration of drugs]. Nihon Naibunpi Gakkai zasshi, 1973, Jun-20, Volume: 49, Issue:6 Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Carcinoma; Cushing Syndrome; Female; Humans; Hydrocortisone; Hyperthyroidism; Liver Diseases; Male; Metyrapone; Middle Aged; Mitotane; Pregnancy; Tuberculosis, Pulmonary	1973
Ectopic adrenocorticotropin syndrome with prostatic carcinoma. Urology, 1973, Volume: 2, Issue:6 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenocarcinoma; Adrenocorticotropic Hormone; Blood Glucose; Dexamethasone; Humans; Male; Metyrapone; Middle Aged; Mitotane; Neoplasm Metastasis; Paraneoplastic Endocrine Syndromes; Potassium; Prostatic Neoplasms; Psychotic Disorders; Spironolactone	1973
Cushing's syndrome due to bilateral adrenal cortical hyperplasia in a 13-year old girl: successful treatment with op'DDD'. Helvetica paediatrica acta, 1974, Volume: 29, Issue:3 Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Adrenal Gland Diseases; Body Height; Body Weight; Cortisone; Cushing Syndrome; Female; Fludrocortisone; Humans; Hydrocortisone; Hyperplasia; Metyrapone; Mitotane	1974
Carcinoma of the adrenal cortex: clinical description, diagnosis, and treatment. International advances in surgical oncology, 1984, Volume: 7 Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Aminoglutethimide; Antineoplastic Agents; Combined Modality Therapy; Diagnosis, Differential; Humans; Metyrapone; Mitotane; Prognosis; Radiotherapy Dosage	1984
Clotting changes in Cushing's syndrome: elevated factor VIII activity. Folia haematologica (Leipzig, Germany : 1928), 1983, Volume: 110, Issue:2 Topics: Adrenalectomy; Blood Coagulation; Blood Coagulation Tests; Cushing Syndrome; Factor VIII; Female; Humans; Hydrocortisone; Male; Metyrapone; Mitotane; Thromboembolism	1983
[Cushing's syndrome. Medical treatment of adrenal hypercorticism]. Hormone research, 1980, Volume: 13, Issue:4-5 Topics: Adrenal Gland Neoplasms; Aminoglutethimide; Androstanols; Bromocriptine; Cushing Syndrome; Cyproheptadine; Dihydrotestosterone; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Metyrapone; Mitotane; Nitriles	1980
Adrenal carcinoma. Current therapy in endocrinology and metabolism, 1994, Volume: 5 Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aminoglutethimide; Carcinoma; Cushing Syndrome; Diagnosis, Differential; Humans; Metyrapone; Mitotane; Neoplasm Metastasis	1994
In vitro bioactivation of the environmental pollutant 3-methylsulphonyl-2, 2-bis(4-chlorophenyl)-1,1-dichloroethene in the human adrenal gland. Toxicology letters, 1994, Volume: 71, Issue:2 Topics: Adrenal Glands; Binding Sites; Biotransformation; Cytochrome P-450 Enzyme System; Dichlorodiphenyl Dichloroethylene; Female; Glutathione; Humans; In Vitro Techniques; Metyrapone; Middle Aged; Mitochondria; Mitotane; Protein Binding	1994
Acquired immune deficiency syndrome: the glucocorticoid solution. Medical hypotheses, 1996, Volume: 47, Issue:1 Topics: Acquired Immunodeficiency Syndrome; Adrenocorticotropic Hormone; Aminoglutethimide; CD8-Positive T-Lymphocytes; Corticotropin-Releasing Hormone; Glucocorticoids; HIV; HIV Envelope Protein gp120; Humans; Hydrocortisone; Interleukin-1; Lymphocyte Activation; Metyrapone; Mitotane; Models, Biological; Receptors, Pituitary Hormone; T-Lymphocytes	1996
Primary culture system of adrenocortical cells from dogs to evaluate direct effects of chemicals on steroidogenesis. Toxicology, 2001, Aug-28, Volume: 165, Issue:2-3 Topics: Adrenal Cortex; Adrenal Cortex Hormones; Aminoglutethimide; Animals; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Dogs; Female; Ketoconazole; Metyrapone; Miconazole; Mitotane; Toxicity Tests	2001
Pharmacological management of Cushing's syndrome: an update. Arquivos brasileiros de endocrinologia e metabologia, 2007, Volume: 51, Issue:8 Topics: Cushing Syndrome; Dopamine Antagonists; Hormone Antagonists; Humans; Hypothalamo-Hypophyseal System; Ketoconazole; Metyrapone; Mifepristone; Mitotane; Pituitary-Adrenal System; PPAR gamma; Somatostatin; Steroids	2007
A patient with ectopic cortisol production derived from malignant testicular masses. Nature clinical practice. Endocrinology & metabolism, 2008, Volume: 4, Issue:12 Topics: Adrenal Rest Tumor; Adrenocortical Carcinoma; Adrenocorticotropic Hormone; Aged; Cushing Syndrome; Humans; Hydrocortisone; Male; Metyrapone; Mitotane; Testicular Neoplasms	2008
Mitotane, metyrapone, and ketoconazole combination therapy as an alternative to rescue adrenalectomy for severe ACTH-dependent Cushing's syndrome. The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:9 Topics: Adolescent; Adult; Aged; Antimetabolites; Antineoplastic Agents; Cushing Syndrome; Drug Therapy, Combination; Female; Humans; Hydrocortisone; Ketoconazole; Male; Metyrapone; Middle Aged; Mitotane; Treatment Outcome	2011
Adding metyrapone to chemotherapy plus mitotane for Cushing's syndrome due to advanced adrenocortical carcinoma. Endocrine, 2018, Volume: 61, Issue:1 Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Cushing Syndrome; Drug Therapy, Combination; Feasibility Studies; Humans; Hydrocortisone; Male; Metyrapone; Middle Aged; Mitotane; Treatment Outcome	2018
CYP11B1 has no role in mitotane action and metabolism in adrenocortical carcinoma cells. PloS one, 2018, Volume: 13, Issue:5 Topics: Adrenocortical Carcinoma; Antineoplastic Agents, Hormonal; Cell Line, Tumor; Cell Proliferation; Humans; Metyrapone; Mitotane; Steroid 11-beta-Hydroxylase	2018