mitotane has been researched along with dichlorodiphenyl dichloroethylene in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (34.62) | 18.7374 |
| 1990's | 4 (15.38) | 18.2507 |
| 2000's | 7 (26.92) | 29.6817 |
| 2010's | 6 (23.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bogdan, A; Desgrez, P; Legrand, JC; Touitou, Y | 1 |
| Eliel, LP; Turner, RT | 1 |
| Bogdan, A; Touitou, Y | 1 |
| Moolenaar, AJ; Niewint, JW; Oei, IT | 1 |
| Sieber, SM | 1 |
| Benecke, R; De Zeeuw, RA; Vetter, B | 1 |
| Auzéby, A; Bogdan, A; Luton, JP; Moolenaar, AJ; Touitou, Y | 1 |
| Ilan, Z; Yaron, Z | 1 |
| Bercovici, B; Cucos, S; Ron, M; Wassermann, D; Wassermann, M | 1 |
| Jönsson, CJ; Lund, BO | 1 |
| Andersen, A; Nome, O; Slørdal, L; Vesterhus, L; Warren, DJ | 1 |
| Diez, MJ; Fernández, N; García, JJ; Sahagún, AM; Sierra, M; Terán, MT | 1 |
| Balaguer, P; Boussioux, AM; Casellas, C; Comunale, F; Fenet, H; François, F; Nicolas, JC; Pons, M | 1 |
| Carlson, DB; Curtis, LR; Williams, DE | 1 |
| Chan, S; Foster, W; Hughes, C; Platt, L | 1 |
| Brandt, I; Lindhe, O; Skogseid, B | 1 |
| Bergman, A; Brandt, I; Cantillana, T; Hermansson, V; Hovander, L; Ljungvall, K; Magnusson, U; Törneke, K | 1 |
| Asp, V; Bergman, A; Bergström, U; Brandt, I; Hermansson, V | 1 |
| Gregoraszczuk, EŁ; Kajta, M; Wójtowicz, AK | 1 |
| Bergman, A; Cantillana, T; Sundström, M | 1 |
| Banas, D; Brun-Bellut, J; Feidt, C; Lazartigues, A; Thomas, M | 1 |
| Bandini, A; Bani, D; Canu, L; Cini, N; Fucci, R; Guasti, D; Luconi, M; Mannelli, M; Poli, G; Rapizzi, E | 1 |
| Allolio, B; Baudin, E; Chadarevian, R; Fassnacht, M; Haak, HR; Kerkhofs, TM; Leboulleux, S; Mantero, F; Mueller, HH; Skogseid, B; Terzolo, M | 1 |
| Bailey, TD; Buckley, DD; Carter, S; Helms, K; Heubi, JE; Jandacek, RJ; Khoury, JC; Olson, JR; Pavuk, M; Shelton, C; Sjödin, A; Tso, P; Turner, WE | 1 |
| Haefeli, WE; Theile, D; Weiss, J | 1 |
| Al Antary, TM; Alawi, MA; Estityah, H; Haddad, N | 1 |
1 review(s) available for mitotane and dichlorodiphenyl dichloroethylene
| Article | Year |
|---|---|
[Metabolism of o,p'-DDD (mitotane) in human and animals. Actual notions and practical deductions (author's transl)].
Topics: Animals; DDT; Dichlorodiphenyl Dichloroethylene; Dichlorodiphenyldichloroethane; Feces; Humans; Isomerism; Mitotane; Species Specificity; Structure-Activity Relationship | 1977 |
2 trial(s) available for mitotane and dichlorodiphenyl dichloroethylene
| Article | Year |
|---|---|
Comparison of two mitotane starting dose regimens in patients with advanced adrenocortical carcinoma.
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biotransformation; Dichlorodiphenyl Dichloroethylene; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Mitotane; Neoplasm Staging; Neurotoxicity Syndromes; Phenylacetates; Severity of Illness Index | 2013 |
Reduction of the body burden of PCBs and DDE by dietary intervention in a randomized trial.
Topics: Aged; Alabama; Body Burden; Dichlorodiphenyl Dichloroethylene; Double-Blind Method; Fatty Acids; Female; Humans; Male; Mitotane; Patient Compliance; Plant Oils; Polychlorinated Biphenyls; Sucrose; Treatment Outcome | 2014 |
23 other study(ies) available for mitotane and dichlorodiphenyl dichloroethylene
| Article | Year |
|---|---|
o,p'-DDT as an estrogen: an evaluation of its ability to compete with 3H-estradiol for nuclear estrogen receptor sites in the quail oviduct.
Topics: Animals; Binding, Competitive; DDT; Dichlorodiphenyl Dichloroethylene; Estradiol; Estrogens, Non-Steroidal; Female; Isomerism; Mitotane; Oviducts; Quail; Receptors, Estrogen | 1978 |
Influences of op'DDD, op'DDE and solubilization procedures on the in vitro biosynthesis of 18-hydroxycorticosterone and aldosterone by sheep adrenals.
Topics: 18-Hydroxycorticosterone; Adrenal Glands; Aldosterone; Animals; Corticosterone; Dichlorodiphenyl Dichloroethylene; Dose-Response Relationship, Drug; Male; Mitotane; Sex Factors; Sheep; Solubility | 1978 |
Estimation of o,p'-DDD in plasma by gas-liquid chromatography.
Topics: Chromatography, Gas; Dichlorodiphenyl Dichloroethylene; Humans; Methods; Mitotane | 1977 |
The lymphocytic absorption of p,p'-DDT and some structurally-related compounds in the rat.
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Bile; DDT; Dichlorodiphenyl Dichloroethylene; Dichlorodiphenyldichloroethane; Intestines; Lipid Metabolism; Lymph; Male; Mitotane; Rats; Solutions; Time Factors | 1976 |
Rapid micromethod for the analysis of mitotane and its metabolite in plasma by gas chromatography with electron-capture detection.
Topics: Child; Chromatography, Gas; Cushing Syndrome; Dichlorodiphenyl Dichloroethylene; Dichlorodiphenyldichloroethane; Electrochemistry; Humans; Indicators and Reagents; Mitotane | 1987 |
o,p'-DDD (mitotane) treatment for Cushing's syndrome: adrenal drug concentration and inhibition in vitro of steroid synthesis.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Carcinoma; Child; Cortodoxone; Cushing Syndrome; Desoxycorticosterone; Dichlorodiphenyl Dichloroethylene; Female; Humans; Hydroxyprogesterones; Hyperplasia; In Vitro Techniques; Male; Middle Aged; Mitotane; Steroids | 1985 |
Suppression by organochlorines of the response to adrenocorticotrophin of the interrenal tissue in Sarotherodon aureus (Teleostei).
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Aroclors; Bucladesine; DDT; Depression, Chemical; Dichlorodiphenyl Dichloroethylene; Dose-Response Relationship, Drug; Fishes; Hydrocortisone; In Vitro Techniques; Interrenal Gland; Mitotane | 1980 |
Storage of some organochlorine compounds in toxemia of pregnancy.
Topics: Adult; Chromatography; Chromatography, Gas; DDT; Dichlorodiphenyl Dichloroethylene; Female; Humans; Insecticides; Mitotane; Polychlorinated Biphenyls; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Third | 1980 |
In vitro bioactivation of the environmental pollutant 3-methylsulphonyl-2, 2-bis(4-chlorophenyl)-1,1-dichloroethene in the human adrenal gland.
Topics: Adrenal Glands; Binding Sites; Biotransformation; Cytochrome P-450 Enzyme System; Dichlorodiphenyl Dichloroethylene; Female; Glutathione; Humans; In Vitro Techniques; Metyrapone; Middle Aged; Mitochondria; Mitotane; Protein Binding | 1994 |
A high-pressure liquid chromatographic method for measuring mitotane [1,1-(o,p'-Dichlorodiphenyl)-2,2-dichloroethane] and its metabolite 1,1-(o,p'-Dichlorodiphenyl)-2,2-dichloroethene in plasma.
Topics: Absorption; Adolescent; Adrenal Cortex Neoplasms; Antineoplastic Agents, Hormonal; Carcinoma; Chromatography, High Pressure Liquid; Dichlorodiphenyl Dichloroethylene; Drug Stability; Female; Humans; Mitotane; Spectrophotometry, Ultraviolet | 1995 |
Organochlorine pesticide residues in muscle tissue of rainbow trout, Oncorhynchus mykiss, taken from four fish farms in León, Spain.
Topics: Aldrin; Animals; DDT; Dichlorodiphenyl Dichloroethylene; Dichlorodiphenyldichloroethane; Dieldrin; Female; Fisheries; Food Contamination; Heptachlor Epoxide; Hexachlorocyclohexane; Insecticides; Male; Mitotane; Muscle, Skeletal; Oncorhynchus mykiss; Pesticide Residues; Spain | 1998 |
Reporter cell lines to study the estrogenic effects of xenoestrogens.
Topics: Cell Line; Dichlorodiphenyl Dichloroethylene; Dioxins; Environmental Monitoring; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens, Non-Steroidal; Genes, Reporter; HeLa Cells; Humans; Luciferases; Mitotane; Phenols; Receptors, Estrogen; Sewage; Transfection; Water Pollutants, Chemical | 1999 |
Salmonid sexual development is not consistently altered by embryonic exposure to endocrine-active chemicals.
Topics: Animals; Chlordecone; Dichlorodiphenyl Dichloroethylene; Disorders of Sex Development; Drug Evaluation, Preclinical; Embryo, Nonmammalian; Environmental Monitoring; Estrogens; Female; Gonads; Insecticides; Male; Maternal Exposure; Microinjections; Mitotane; Oncorhynchus mykiss; Pesticide Residues; Phenols; Salmon; Sex Differentiation | 2000 |
Detection of endocrine disrupting chemicals in samples of second trimester human amniotic fluid.
Topics: Adult; Amniotic Fluid; Dichlorodiphenyl Dichloroethylene; Female; Gas Chromatography-Mass Spectrometry; Gestational Age; Hexachlorobenzene; Hexachlorocyclohexane; Humans; Insecticides; Maternal Age; Mitotane; Parity; Pesticides; Pregnancy; Pregnancy Trimester, Second; Pregnancy, High-Risk; Sensitivity and Specificity | 2000 |
Cytochrome P450-catalyzed binding of 3-methylsulfonyl-DDE and o,p'-DDD in human adrenal zona fasciculata/reticularis.
Topics: Adult; Autoradiography; Cytochrome P-450 Enzyme System; Dichlorodiphenyl Dichloroethylene; Female; Hormones; Humans; In Vitro Techniques; Male; Middle Aged; Mitotane; Zona Fasciculata; Zona Reticularis | 2002 |
Pharmacokinetics of the adrenocorticolytic compounds 3-methylsulphonyl-DDE and o,p'-DDD (mitotane) in Minipigs.
Topics: Adipose Tissue; Adrenal Cortex; Animals; Antineoplastic Agents, Hormonal; Area Under Curve; Biotransformation; Chromatography, Gas; Data Interpretation, Statistical; Dichlorodiphenyl Dichloroethylene; Electrochemistry; Liver; Mitotane; Subcutaneous Fat; Swine; Swine, Miniature; Tissue Distribution | 2008 |
Comparative CYP-dependent binding of the adrenocortical toxicants 3-methylsulfonyl-DDE and o,p'-DDD in Y-1 adrenal cells.
Topics: Adrenal Glands; Animals; Cell Line; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dichlorodiphenyl Dichloroethylene; Female; Glutathione; Mice; Mice, Inbred C57BL; Mitotane; Protein Binding; Sulfhydryl Compounds | 2007 |
DDT- and DDE-induced disruption of ovarian steroidogenesis in prepubertal porcine ovarian follicles: a possible interaction with the main steroidogenic enzymes and estrogen receptor beta.
Topics: Animals; Aromatase; Cells, Cultured; DDT; Dichlorodiphenyl Dichloroethylene; Dose-Response Relationship, Drug; Estradiol; Estrogen Receptor beta; Female; Granulosa Cells; Isomerism; Mitotane; Ovarian Follicle; Pesticides; Progesterone; Steroids; Swine; Theca Cells | 2007 |
Synthesis of 2-(4-chlorophenyl)-2-(4-chloro-3-thiophenol)-1,1-dichloroethene (3-SH-DDE) via Newman-Kwart rearrangement - a precursor for synthesis of radiolabeled and unlabeled alkylsulfonyl-DDEs.
Topics: Dichlorodiphenyl Dichloroethylene; Insecticides; Isotope Labeling; Mitotane | 2009 |
Organochlorine pesticides and polychlorinated biphenyls in sediments and fish from freshwater cultured fish ponds in different agricultural contexts in north-eastern France.
Topics: Agriculture; Aldrin; Animals; Aquaculture; Carps; DDT; Dichlorodiphenyl Dichloroethylene; Dichlorodiphenyldichloroethane; Endosulfan; France; Heptachlor; Hexachlorobenzene; Hexachlorocyclohexane; Hydrocarbons, Chlorinated; Mitotane; Perches; Pesticides; Polychlorinated Biphenyls; Ponds; Water Pollutants, Chemical | 2012 |
Morphofunctional effects of mitotane on mitochondria in human adrenocortical cancer cells.
Topics: Adrenal Cortex Neoplasms; Antineoplastic Agents, Hormonal; Apoptosis; Cell Line, Tumor; Cell Survival; Dichlorodiphenyl Dichloroethylene; Humans; Membrane Potential, Mitochondrial; Mitochondria; Mitotane; Oxygen | 2013 |
Effects of adrenolytic mitotane on drug elimination pathways assessed in vitro.
Topics: Adrenal Cortex Neoplasms; Antineoplastic Agents, Hormonal; ATP-Binding Cassette Transporters; Biotransformation; Carrier Proteins; Cell Line, Tumor; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Dichlorodiphenyl Dichloroethylene; Dichlorodiphenyldichloroethane; Drug Interactions; Genes, Reporter; Humans; Mitotane; RNA, Messenger | 2015 |
Organochlorine Pesticides Residues in Human Breast Milk from the Middle Governorates in Jordan in 2013/2014.
Topics: Aldrin; DDT; Dichlorodiphenyl Dichloroethylene; Dieldrin; Endosulfan; Environmental Exposure; Heptachlor; Hexachlorocyclohexane; Humans; Hydrocarbons, Chlorinated; Jordan; Milk, Human; Mitotane; Pesticide Residues; Pesticides | 2017 |