mitotane has been researched along with dactinomycin in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barrows, LR; Ireland, CM; Kokoshka, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Bates, SE; Dichek, HL; Fojo, AT; Gazdar, A; Loriaux, DL; Mickley, LA; Shieh, CY | 1 |
| Greenwald, ES | 1 |
| Belani, CP; Gutheil, JC; Hart, SR; Hussain, A; Melera, PW | 1 |
2 review(s) available for mitotane and dactinomycin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Cancer chemotherapy. II.
Topics: Animals; Antineoplastic Agents; Asparaginase; Azathioprine; Bleomycin; Cytarabine; Dactinomycin; Daunorubicin; Dimethylamines; Doxorubicin; Floxuridine; Fluorouracil; Humans; Hydroxyurea; Imidazoles; Mercaptopurine; Mitomycins; Mitotane; Neoplasms; Nitrosourea Compounds; Pipobroman; Procarbazine; Streptonigrin; Streptozocin; Thioguanine; Triazenes; Triazines; Vinblastine; Vincristine | 1972 |
4 other study(ies) available for mitotane and dactinomycin
| Article | Year |
|---|---|
Cell-based screen for identification of inhibitors of tubulin polymerization.
Topics: Animals; Brain Neoplasms; Bucladesine; Cell Differentiation; Drug Screening Assays, Antitumor; Formazans; Glioma; Rats; Tubulin; Tumor Cells, Cultured | 1996 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Mitotane enhances cytotoxicity of chemotherapy in cell lines expressing a multidrug resistance gene (mdr-1/P-glycoprotein) which is also expressed by adrenocortical carcinomas.
Topics: Adrenal Cortex Neoplasms; Affinity Labels; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cell Survival; Dactinomycin; Dihydropyridines; Drug Resistance; Gene Expression; Humans; Membrane Glycoproteins; Mitotane; Nucleic Acid Hybridization; RNA, Messenger; Tumor Cells, Cultured; Vinblastine | 1991 |
Alterations in Ca2+ transport ATPase and P-glycoprotein expression can mediate resistance to thapsigargin.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Calcium-Transporting ATPases; Carrier Proteins; Cell Division; Cell Line; Cell Survival; Colchicine; Cricetinae; Cricetulus; Dactinomycin; Daunorubicin; Dihydropyridines; DNA, Complementary; Drug Resistance; Gene Expression; Lung; Membrane Glycoproteins; Mitotane; Multigene Family; Substrate Specificity; Terpenes; Thapsigargin; Transfection; Vincristine | 1994 |