mitotane and 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene

mitotane has been researched along with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene in 21 studies

Research

Studies (21)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (4.76)	18.7374
1990's	3 (14.29)	18.2507
2000's	9 (42.86)	29.6817
2010's	8 (38.10)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Benecke, R; de Zeeuw, RA; Keller, E; Vetter, B	1
Inouye, M; Mio, T; Sumino, K	1
Andersen, A; Kasperlik-Zaluska, AA; Warren, DJ	1
Balaguer, P; Boussioux, AM; Casellas, C; Comunale, F; Fenet, H; François, F; Nicolas, JC; Pons, M	1
Carlson, DB; Curtis, LR; Williams, DE	1
Chan, S; Foster, W; Hughes, C; Platt, L	1
Giesy, JP; Meadows, J; Noltie, DB; Papoulias, DM; Tillitt, DE; Villalobos, SA	1
Blankenship, AL; Giesy, JP; Meadows, J; Papoulias, DM; Pastva, SD; Tillitt, DE; Villalobos, SA	1
Clements, S; Crippen, TL; Feist, G; Fitzpatrick, MS; Gundersen, D; Leong, J; Milston, RH; Schreck, CB; Vella, AT	1
Foster, WG; Wu, Y; Younglai, EV	1
Cichocki, A; Kasperlik-Zaluska, AA	1
Gregoraszczuk, EŁ; Kajta, M; Wójtowicz, AK	1
Davis, LK; Grau, EG; Hiramatsu, N; Hirano, T; Riley, LG; Sullivan, CV; Visitacion, N	1
Allolio, B; Baudin, E; Berruti, A; Chadarevian, R; Daffara, F; den Hartigh, J; Fassnacht, M; Haak, HR; Hermsen, IG; Houterman, S; Leboulleux, S; Schlumberger, M; Terzolo, M	1
Banas, D; Brun-Bellut, J; Feidt, C; Lazartigues, A; Thomas, M	1
Bonefeld-Jørgensen, EC; Erdmann, SE; Knudsen, LE; Long, M; Mathiesen, L; Mørck, TA; Nielsen, F; Siersma, VD	1
Bailey, TD; Buckley, DD; Carter, S; Helms, K; Heubi, JE; Jandacek, RJ; Khoury, JC; Olson, JR; Pavuk, M; Shelton, C; Sjödin, A; Tso, P; Turner, WE	1
Li, G; Li, Y; Liang, T; Ren, D; Wang, P; Xiao, K; Zhang, H; Zhang, Q	1
Fassnacht, M; Heinz, W; Kendl, S; Klinker, H; Kroiss, M; Lapa, C; Plonné, D; Ronchi, CL; Sbiera, S; Schirbel, A; Schirmer, D; Zink, M	1
Al Antary, TM; Alawi, MA; Estityah, H; Haddad, N	1
Allegra, S; Berruti, A; Carrella, S; Cusato, J; D'Avolio, A; Daffara, FC; De Francia, S; De Martino, F; Di Carlo, F; Ferrero, A; Piccione, FM; Pirro, E; Tampellini, M; Terzolo, M	1

Trials

2 trial(s) available for mitotane and 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene

Article	Year
Determination of mitotane (o,p-DDD) and its metabolites o,p-DDA and o,p-DDE in plasma by high-performance liquid chromatography. Therapeutic drug monitoring, 1999, Volume: 21, Issue:3 Topics: Adrenal Cortex Neoplasms; Adrenergic Agents; Adult; Aged; Antineoplastic Agents, Hormonal; Chromatography, High Pressure Liquid; Drug Stability; Female; Humans; Linear Models; Male; Middle Aged; Mitotane	1999
Reduction of the body burden of PCBs and DDE by dietary intervention in a randomized trial. The Journal of nutritional biochemistry, 2014, Volume: 25, Issue:4 Topics: Aged; Alabama; Body Burden; Dichlorodiphenyl Dichloroethylene; Double-Blind Method; Fatty Acids; Female; Humans; Male; Mitotane; Patient Compliance; Plant Oils; Polychlorinated Biphenyls; Sucrose; Treatment Outcome	2014

Other Studies

19 other study(ies) available for mitotane and 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene

Article	Year
Plasma level monitoring of mitotane (o,p'-DDD) and its metabolite (o,p'-DDE) during long-term treatment of Cushing's disease with low doses. European journal of clinical pharmacology, 1991, Volume: 41, Issue:3 Topics: Adolescent; Adult; Cushing Syndrome; Female; Humans; Male; Mitotane; Time Factors	1991
Use of GC/MS/SIM for rapid determination of plasma levels of o,p'-DDD, o,p'-DDE and o,p'-DDA. Clinica chimica acta; international journal of clinical chemistry, 1987, Volume: 170, Issue:2-3 Topics: Circadian Rhythm; Gas Chromatography-Mass Spectrometry; Humans; Mitotane	1987
Reporter cell lines to study the estrogenic effects of xenoestrogens. The Science of the total environment, 1999, Aug-15, Volume: 233, Issue:1-3 Topics: Cell Line; Dichlorodiphenyl Dichloroethylene; Dioxins; Environmental Monitoring; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens, Non-Steroidal; Genes, Reporter; HeLa Cells; Humans; Luciferases; Mitotane; Phenols; Receptors, Estrogen; Sewage; Transfection; Water Pollutants, Chemical	1999
Salmonid sexual development is not consistently altered by embryonic exposure to endocrine-active chemicals. Environmental health perspectives, 2000, Volume: 108, Issue:3 Topics: Animals; Chlordecone; Dichlorodiphenyl Dichloroethylene; Disorders of Sex Development; Drug Evaluation, Preclinical; Embryo, Nonmammalian; Environmental Monitoring; Estrogens; Female; Gonads; Insecticides; Male; Maternal Exposure; Microinjections; Mitotane; Oncorhynchus mykiss; Pesticide Residues; Phenols; Salmon; Sex Differentiation	2000
Detection of endocrine disrupting chemicals in samples of second trimester human amniotic fluid. The Journal of clinical endocrinology and metabolism, 2000, Volume: 85, Issue:8 Topics: Adult; Amniotic Fluid; Dichlorodiphenyl Dichloroethylene; Female; Gas Chromatography-Mass Spectrometry; Gestational Age; Hexachlorobenzene; Hexachlorocyclohexane; Humans; Insecticides; Maternal Age; Mitotane; Parity; Pesticides; Pregnancy; Pregnancy Trimester, Second; Pregnancy, High-Risk; Sensitivity and Specificity	2000
In ovo exposure to o,p -DDE affects sexual development but not sexual differentiation in Japanese medaka (Oryzias latipes). Environmental health perspectives, 2003, Volume: 111, Issue:1 Topics: Animals; Dose-Response Relationship, Drug; Female; Gonads; Hermaphroditic Organisms; Male; Microinjections; Mitotane; Oryzias; Sex Determination Processes; Sex Differentiation	2003
Toxicity of o,p'-DDE to medaka d-rR strain after a one-time embryonic exposure by in ovo nanoinjection: an early through juvenile life cycle assessment. Chemosphere, 2003, Volume: 53, Issue:8 Topics: Animals; Embryo, Nonmammalian; Lethal Dose 50; Life Cycle Stages; Microinjections; Mitotane; No-Observed-Adverse-Effect Level; Oryzias; Ovum; Toxicity Tests, Acute	2003
Short-term exposure of Chinook salmon (Oncoryhnchus tshawytscha) to o,p-DDE or DMSO during early life-history stages causes long-term humoral immunosuppression. Environmental health perspectives, 2003, Volume: 111, Issue:13 Topics: Animals; Antibody Formation; Dimethyl Sulfoxide; Female; Gonads; Immune Tolerance; Larva; Male; Mitotane; Salmon; Sex Ratio; Solvents; Water Pollutants, Chemical	2003
Rapid effects of pesticides on human granulosa-lutein cells. Reproduction (Cambridge, England), 2006, Volume: 131, Issue:2 Topics: Calcium; Calcium Signaling; Calcium-Transporting ATPases; Cells, Cultured; Chlordecone; Cytosol; Enzyme Inhibitors; Female; Fura-2; Humans; Indoles; Luteal Cells; Methoxychlor; Microscopy, Fluorescence; Mitotane; Pertussis Toxin; Pesticides; Progesterone; Sarcoplasmic Reticulum; Signal Processing, Computer-Assisted; Thapsigargin; Time Factors	2006
Clinical role of determination of plasma mitotane and its metabolites levels in patients with adrenal cancer: results of a long-term follow-up. Journal of experimental therapeutics & oncology, 2005, Volume: 5, Issue:2 Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Antineoplastic Agents, Hormonal; Child; Female; Follow-Up Studies; Humans; Male; Middle Aged; Mitotane	2005
DDT- and DDE-induced disruption of ovarian steroidogenesis in prepubertal porcine ovarian follicles: a possible interaction with the main steroidogenic enzymes and estrogen receptor beta. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2007, Volume: 58, Issue:4 Topics: Animals; Aromatase; Cells, Cultured; DDT; Dichlorodiphenyl Dichloroethylene; Dose-Response Relationship, Drug; Estradiol; Estrogen Receptor beta; Female; Granulosa Cells; Isomerism; Mitotane; Ovarian Follicle; Pesticides; Progesterone; Steroids; Swine; Theca Cells	2007
Effects of o,p'-DDE, heptachlor, and 17beta-estradiol on vitellogenin gene expression and the growth hormone/insulin-like growth factor-I axis in the tilapia, Oreochromis mossambicus. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2009, Volume: 149, Issue:4 Topics: Animals; Estradiol; Growth Hormone; Heptachlor; Insulin-Like Growth Factor I; Male; Mitotane; Tilapia; Vitellogenins	2009
Plasma concentrations of o,p'DDD, o,p'DDA, and o,p'DDE as predictors of tumor response to mitotane in adrenocortical carcinoma: results of a retrospective ENS@T multicenter study. The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:6 Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Female; Humans; Male; Middle Aged; Mitotane; Predictive Value of Tests; Retrospective Studies; Sensitivity and Specificity	2011
Organochlorine pesticides and polychlorinated biphenyls in sediments and fish from freshwater cultured fish ponds in different agricultural contexts in north-eastern France. Ecotoxicology and environmental safety, 2012, Volume: 77 Topics: Agriculture; Aldrin; Animals; Aquaculture; Carps; DDT; Dichlorodiphenyl Dichloroethylene; Dichlorodiphenyldichloroethane; Endosulfan; France; Heptachlor; Hexachlorobenzene; Hexachlorocyclohexane; Hydrocarbons, Chlorinated; Mitotane; Perches; Pesticides; Polychlorinated Biphenyls; Ponds; Water Pollutants, Chemical	2012
PCB concentrations and dioxin-like activity in blood samples from Danish school children and their mothers living in urban and rural areas. Basic & clinical pharmacology & toxicology, 2014, Volume: 115, Issue:1 Topics: Adult; Body Height; Body Mass Index; Body Weight; Child; DDT; Dioxins; Environmental Pollutants; Female; Hexachlorocyclohexane; Humans; Male; Middle Aged; Mitotane; Mothers; Polychlorinated Biphenyls; Rural Population; Urban Population	2014
[Identification of two interference peaks during dioxin analysis for biological samples]. Se pu = Chinese journal of chromatography, 2014, Volume: 32, Issue:9 Topics: Benzofurans; DDT; Dioxins; Gas Chromatography-Mass Spectrometry; Hydrocarbons, Chlorinated; Mitotane; Pesticides; Polychlorinated Dibenzodioxins	2014
Association of mitotane with chylomicrons and serum lipoproteins: practical implications for treatment of adrenocortical carcinoma. European journal of endocrinology, 2016, Volume: 174, Issue:3 Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Aged; Antineoplastic Agents, Hormonal; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Chyle; Chylomicrons; Cohort Studies; Endoplasmic Reticulum Stress; Female; Gastrointestinal Absorption; Humans; Lipoproteins; Lipoproteins, HDL2; Lipoproteins, IDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Middle Aged; Mitotane	2016
Organochlorine Pesticides Residues in Human Breast Milk from the Middle Governorates in Jordan in 2013/2014. Bulletin of environmental contamination and toxicology, 2017, Volume: 99, Issue:1 Topics: Aldrin; DDT; Dichlorodiphenyl Dichloroethylene; Dieldrin; Endosulfan; Environmental Exposure; Heptachlor; Hexachlorocyclohexane; Humans; Hydrocarbons, Chlorinated; Jordan; Milk, Human; Mitotane; Pesticide Residues; Pesticides	2017
Circannual variation of mitotane and its metabolites plasma levels in patients with adrenocortical carcinoma. The Journal of pharmacy and pharmacology, 2017, Volume: 69, Issue:11 Topics: Adipose Tissue; Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Antineoplastic Agents, Hormonal; Chemotherapy, Adjuvant; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Mitotane; Seasons; Sex Factors; Time Factors; Young Adult	2017