mitoquinone has been researched along with quinone* in 1 studies
1 other study(ies) available for mitoquinone and quinone
| Article | Year |
|---|---|
Increased levels of circulating oxidized mitochondrial DNA contribute to chronic inflammation in metabolic syndrome, and MitoQ-based antioxidant therapy alleviates this DNA-induced inflammation.
Here, the aim was to investigate the role of circulating oxidized mitochondrial DNA (ox-mtDNA) in metabolic syndrome (MetS)-associated chronic inflammation and evaluate the effect of Mito-Quinone (MitoQ)-based antioxidant therapy on inflammation. A total of 112 MetS patients and 111 healthy control individuals (HCs) were recruited. Peripheral blood was collected, and mononuclear cells (PBMCs) were separated. In a preclinical study, MitoQ, a mitochondrial-targeted antioxidant, was administered to Sprague-Dawley (SD) rats fed a high-fat diet (HFD). In vitro, H Topics: Animals; Antioxidants; Cell-Free Nucleic Acids; DNA, Mitochondrial; Hydrogen Peroxide; Inflammation; Metabolic Syndrome; NF-kappa B; Rats; Rats, Sprague-Dawley; Toll-Like Receptor 9; Ubiquinone | 2023 |