mitomycin has been researched along with tirapazamine in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.76) | 18.7374 |
| 1990's | 10 (58.82) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 1 (5.88) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Sugget, N; Walton, MI; Workman, P | 1 |
| Durand, RE; Olive, PL | 1 |
| Riley, RJ; Workman, P | 1 |
| Adams, GE; Bowler, J; Bremner, JC; Stratford, IJ | 1 |
| Adams, GE; Godden, J; Keohane, A; Stratford, IJ | 1 |
| Stephens, MA; Stratford, IJ | 1 |
| Kennedy, KA | 1 |
| Abe, M; Murata, R; Oya, N; Sasai, K; Shibamoto, Y; Shibata, T; Takagi, T | 1 |
| Chaplin, DJ; Skarsgard, LD; Skwarchuk, MW; Vinczan, A | 1 |
| Akaboshi, M; Hori, H; Kinashi, Y; Masunaga, S; Ono, K; Shibata, T; Suzuki, M; Takagaki, M | 1 |
| Boyer, MJ | 1 |
| Melo, T; Misra, V; Rauth, AM | 1 |
| Hori, H; Kasai, S; Kinashi, Y; Masunaga, SI; Nagasawa, H; Ono, K; Suzuki, M; Takagaki, M; Uto, Y | 1 |
| Sandler, A | 1 |
| Cowen, RL; McKeown, SR; Williams, KJ | 1 |
| Bao, X; Ding, H; He, JX; Miao, ZH; Song, S; Tan, J; Xiong, C; Zhang, A; Zhang, N; Zhao, J; Zhou, L | 1 |
5 review(s) available for mitomycin and tirapazamine
| Article | Year |
|---|---|
DT-diaphorase and cancer chemotherapy.
Topics: Animals; Antineoplastic Agents; Aziridines; Benzoquinones; Dihydrolipoamide Dehydrogenase; Drug Design; Enzyme Induction; Gene Expression Regulation, Enzymologic; Humans; Indolequinones; Indoles; Mitomycin; Neoplasms; Precancerous Conditions; Tirapazamine; Triazines | 1992 |
Hypoxic cells as specific drug targets for chemotherapy.
Topics: Animals; Antineoplastic Agents; DNA Damage; DNA Repair; Humans; Misonidazole; Mitomycin; Mitomycins; Oxygen; Tirapazamine; Triazines | 1987 |
Bioreductive agents: a clinical update.
Topics: Antineoplastic Agents; Aziridines; Biotransformation; Clinical Trials as Topic; Humans; Indolequinones; Indoles; Mitomycin; Oxidation-Reduction; Tirapazamine; Triazines | 1997 |
Chemotherapy in metastatic non-small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Carcinoma, Non-Small-Cell Lung; Cisplatin; Clinical Trials as Topic; Deoxycytidine; Docetaxel; Gemcitabine; Humans; Ifosfamide; Irinotecan; Lung Neoplasms; Mitomycin; Paclitaxel; Taxoids; Tirapazamine; Triazines; Vinblastine; Vinorelbine | 2000 |
Bioreductive drugs: from concept to clinic.
Topics: Animals; Anthraquinones; Antineoplastic Agents; Cell Hypoxia; Genetic Therapy; Humans; Mitomycin; Neoplasms; Polycyclic Aromatic Hydrocarbons; Quinones; Radiation-Sensitizing Agents; Tirapazamine; Triazines | 2007 |
12 other study(ies) available for mitomycin and tirapazamine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
The role of human and rodent DT-diaphorase in the reductive metabolism of hypoxic cell cytotoxins.
Topics: Animals; Antineoplastic Agents; Aziridines; Carcinoma 256, Walker; Cell Hypoxia; Colonic Neoplasms; Humans; In Vitro Techniques; Indolequinones; Indoles; Mitomycin; NAD(P)H Dehydrogenase (Quinone); Oxidation-Reduction; Prodrugs; Rats; Tirapazamine; Triazines | 1992 |
Evaluation of bioreductive drugs in multicell spheroids.
Topics: Animals; Antineoplastic Agents; Cell Aggregation; Cell Hypoxia; Cell Survival; Cricetinae; Evaluation Studies as Topic; In Vitro Techniques; Misonidazole; Mitomycin; Models, Biological; Nitrofurans; Porfiromycin; Prodrugs; Tirapazamine; Triazines | 1992 |
Bioreductive drugs and the selective induction of tumour hypoxia.
Topics: Animals; Antineoplastic Agents; Cell Hypoxia; Constriction; Hydralazine; Mice; Mice, Inbred C3H; Misonidazole; Mitomycin; Mitomycins; Radiation-Sensitizing Agents; Sarcoma, Experimental; Tirapazamine; Triazines | 1990 |
The effects of three bioreductive drugs (mitomycin C, RSU-1069 and SR4233) on cell lines selected for their sensitivity to mitomycin C or ionising radiation.
Topics: Animals; Antineoplastic Agents; Cell Hypoxia; Cell Line; Cell Survival; Misonidazole; Mitomycin; Mitomycins; Radiation Tolerance; Radiation-Sensitizing Agents; Tirapazamine; Triazines | 1990 |
The differential hypoxic cytotoxicity of bioreductive agents determined in vitro by the MTT assay.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Colony-Forming Units Assay; Cricetinae; Drug Screening Assays, Antitumor; Mitomycin; Mitomycins; Oxygen; Radiation-Sensitizing Agents; Tetrazolium Salts; Thiazoles; Tirapazamine; Triazines | 1989 |
Assessment of micronucleus induction in SCCVII cells treated with bioreductive agents, WIN 59075 (SR 4233) and mitomycin C, under aerobic and hypoxic conditions.
Topics: Dose-Response Relationship, Drug; Evaluation Studies as Topic; Humans; Micronucleus Tests; Mitomycin; Oxygen; Radiation-Sensitizing Agents; Tirapazamine; Triazines; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1995 |
The effect of low pH and hypoxia on the cytotoxic effects of SR4233 and mitomycin C in vitro.
Topics: Animals; Antineoplastic Agents; Cell Hypoxia; Cells, Cultured; Cricetinae; Cricetulus; Humans; Hydrogen-Ion Concentration; Mitomycin; Radiation-Sensitizing Agents; Tirapazamine; Triazines; Tumor Cells, Cultured | 1994 |
Effects of bioreductive agents, tirapazamine and mitomycin C, on quiescent cell populations in solid tumors, evaluated by micronucleus assay.
Topics: Animals; Antineoplastic Agents; Bromodeoxyuridine; Carcinoma, Squamous Cell; Cell Division; Cisplatin; Cobalt Radioisotopes; Cytochalasin B; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Gamma Rays; Mice; Mice, Inbred C3H; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mitomycin; Mitotic Index; Tirapazamine; Triazines | 1997 |
Bioreductive therapies: an overview of drugs and their mechanisms of action.
Topics: Animals; Antineoplastic Agents; Aziridines; Cell Hypoxia; DNA, Neoplasm; Forecasting; Humans; Indolequinones; Indoles; Misonidazole; Mitomycin; Nitrofurans; Nitroimidazoles; Oxidation-Reduction; Prodrugs; Radiation-Sensitizing Agents; Tirapazamine; Triazines | 1998 |
Usefulness of tirapazamine as a combined agent in chemoradiation and thermo-chemoradiation therapy at mild temperatures: reference to the effect on intratumor quiescent cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bromodeoxyuridine; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Radiation; Doxorubicin; Hyperthermia, Induced; Mice; Mice, Inbred C3H; Micronucleus Tests; Mitomycin; Radiation-Sensitizing Agents; Tirapazamine; Triazines | 2000 |
Development of Potent NEDD8-Activating Enzyme Inhibitors Bearing a Pyrimidotriazole Scaffold.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cisplatin; Drug Design; Enzyme Inhibitors; Humans; Ifosfamide; Mitomycin; Tirapazamine; Tissue Distribution; Ubiquitin-Activating Enzymes; Xenograft Model Antitumor Assays | 2021 |