mitomycin has been researched along with phenobarbital in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Groeneveld, M; van de Straat, R; Vermeulen, NP; Vromans, RM | 1 |
| Kanyár, B; Kerpel-Fronius, S; Lelieveld, P; Pinedo, HM; Stuurman, M; Verwey, J | 1 |
| Barrenscheen, M; Doehmer, J; Glatt, HR; Goeptar, AR; Groot, EJ; Seidel, A; te Koppele, JM; Vermeulen, NP; Wölfel, C | 1 |
1 review(s) available for mitomycin and phenobarbital
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
6 other study(ies) available for mitomycin and phenobarbital
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
One-electron reduction of mitomycin c by rat liver: role of cytochrome P-450 and NADPH-cytochrome P-450 reductase.
Topics: Aerobiosis; Alkylating Agents; Alkylation; Anaerobiosis; Animals; Cytochrome P-450 Enzyme System; Electron Transport; Glucose Oxidase; Hydrogen Peroxide; In Vitro Techniques; Kinetics; Liver; Male; Methylcholanthrene; Microsomes, Liver; Mitomycin; Mitomycins; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Phenobarbital; Rats; Rats, Inbred Strains | 1990 |
Pharmacokinetics and toxicity of mitomycin C in rodents, given alone, in combination, or after induction of microsomal drug metabolism.
Topics: Animals; Drug Interactions; Half-Life; Male; Methylcholanthrene; Microsomes, Liver; Mitomycin; Mitomycins; Phenobarbital; Rats; Rats, Inbred Strains | 1988 |
The cytotoxicity of mitomycin C and adriamycin in genetically engineered V79 cell lines and freshly isolated rat hepatocytes.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cell Death; Cells, Cultured; Cricetinae; Cricetulus; Cyclophosphamide; Cytochrome P-450 Enzyme System; Dihydroxydihydrobenzopyrenes; Doxorubicin; Enzyme Induction; Enzyme Inhibitors; Fibroblasts; L-Lactate Dehydrogenase; Liver; Male; Maleates; Metyrapone; Mitomycin; Phenobarbital; Rats; Rats, Wistar; Transfection | 1995 |