mitomycin has been researched along with n(6)-((dimethylamino)methylene)mitomycin c in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (66.67) | 18.7374 |
| 1990's | 6 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Singh, SV; Xu, BH | 1 |
| Godden, J; Harris, AL; Hickson, ID; Hoban, PR; Robson, CN; Stratford, IJ; Walton, MI; Workman, P | 1 |
| Covey, JM; Dusre, L; Eliot, HM; Rajagopalan, S; Sinha, BK | 1 |
| Keyes, SR; Rockwell, S; Sartorelli, AC | 1 |
| Politi, PM; Rajagopalan, S; Sinha, BK | 1 |
| Keyes, SR; Pritsos, CA; Sartorelli, AC | 1 |
| Brattain, MG; Chakrabarty, S; Long, BH; Stringfellow, DA; Willson, JK; Yeoman, LC | 1 |
| Kollman, PA; Rao, SN; Remers, WA; Wunz, TP | 1 |
| Schurig, JE; Stringfellow, DA | 1 |
| Bregman, CL; Buroker, RA; Comereski, CR; Hirth, RS; Hottendorf, GH; Madissoo, H | 1 |
| Brattain, MG; Chakrabarty, S; Danels, YJ; Long, BH; Willson, JK | 1 |
| Brattain, DE; Brattain, MG; Chakrabarty, S; Long, BH; Willson, JK | 1 |
| Bradner, WT; Catino, JJ; Florczyk, AP; Huftalen, JB; Rose, WC; Schurig, JE | 1 |
| Fracasso, PM; Heimbrook, DC; Keyes, SR; Rockwell, S; Sartorelli, AC; Sligar, SG | 1 |
| Bogardus, JB; Chen, CM; Coppola, WP; Johns, WH; Lipper, RA | 1 |
| Gupta, V; Singh, SV; Xu, BH | 1 |
| Khan, S; O'Brien, PJ; Silva, JM | 1 |
| Greaves, B; Kang, Y; Lambert, PA; Perry, RR | 1 |
18 other study(ies) available for mitomycin and n(6)-((dimethylamino)methylene)mitomycin c
| Article | Year |
|---|---|
Effect of buthionine sulfoximine and ethacrynic acid on cytotoxic activity of mitomycin C analogues BMY 25282 and BMY 25067.
Topics: Animals; Buthionine Sulfoximine; DNA, Neoplasm; Drug Resistance; Drug Screening Assays, Antitumor; Ethacrynic Acid; Glutathione Transferase; Leukemia P388; Methionine Sulfoximine; Mitomycin; Mitomycins; Tumor Stem Cell Assay | 1992 |
Decreased NADPH:cytochrome P-450 reductase activity and impaired drug activation in a mammalian cell line resistant to mitomycin C under aerobic but not hypoxic conditions.
Topics: Aerobiosis; Alkylating Agents; Anaerobiosis; Animals; Biotransformation; Cell Line; Cell Survival; Cricetinae; Cricetulus; Drug Resistance; Female; Hypoxia; Mitomycin; Mitomycins; NADPH-Ferrihemoprotein Reductase; Ovary; Ultraviolet Rays | 1990 |
DNA interstrand cross-link and free radical formation in a human multidrug-resistant cell line from mitomycin C and its analogues.
Topics: Alkylating Agents; Cross-Linking Reagents; Dose-Response Relationship, Drug; Drug Resistance; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; In Vitro Techniques; Mitomycin; Mitomycins; Structure-Activity Relationship; Tumor Cells, Cultured | 1990 |
Modification of the metabolism and cytotoxicity of bioreductive alkylating agents by dicoumarol in aerobic and hypoxic murine tumor cells.
Topics: Aerobiosis; Alkylating Agents; Anaerobiosis; Animals; Biological Transport; Cell Line; Cell Survival; Dicumarol; Doxorubicin; Kinetics; Mammary Neoplasms, Experimental; Methylcholanthrene; Mice; Mitomycin; Mitomycins; Oxidation-Reduction; Porfiromycin; Vitamin K | 1989 |
Free-radical formation by mitomycin C and its novel analogs in cardiac microsomes and the perfused rat heart.
Topics: Animals; Catalase; Electron Spin Resonance Spectroscopy; Free Radicals; Heart; Heart Rate; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Kinetics; Male; Microsomes; Mitomycin; Mitomycins; Myocardium; Perfusion; Rats; Rats, Inbred Strains; Superoxides | 1989 |
Effect of the superoxide dismutase inhibitor, diethyldithiocarbamate, on the cytotoxicity of mitomycin antibiotics.
Topics: Aerobiosis; Animals; Cell Hypoxia; Cell Survival; Ditiocarb; DNA Damage; Free Radicals; Mammary Neoplasms, Experimental; Mice; Mitomycin; Mitomycins; Oxidation-Reduction; Oxygen; Porfiromycin; Superoxide Dismutase; Tumor Cells, Cultured | 1989 |
Overcoming mitomycin C resistance with semisynthetic derivatives.
Topics: Animals; Biotransformation; Carcinoma; Cell Line; Colonic Neoplasms; DNA; Drug Resistance; Humans; Mice; Mitomycin; Mitomycins; Neoplasm Transplantation; Structure-Activity Relationship; Transplantation, Heterologous | 1986 |
Conformations of complexes between mitomycins and decanucleotides. 3. Sequence specificity, binding at C-10, and mitomycin analogues.
Topics: Animals; Base Sequence; Binding Sites; Chemical Phenomena; Chemistry; DNA; Leukemia P388; Mice; Mitomycin; Mitomycins; Models, Molecular; Molecular Conformation; Oligodeoxyribonucleotides | 1988 |
The search for more active and less toxic mitomycin and etoposide analogs.
Topics: Animals; Antineoplastic Agents; Etoposide; Mice; Mitomycin; Mitomycins | 1987 |
Single-dose and multiple-dose intravenous toxicity studies of BMY-25282 in rats.
Topics: Animals; Arteritis; Blood; Body Weight; Creatine Kinase; Digestive System; Female; Heart; Kidney; Kidney Glomerulus; Lung; Male; Mitomycin; Mitomycins; Organ Size; Rats | 1987 |
Circumvention of deficient activation in mitomycin C-resistant human colonic carcinoma cells by the mitomycin C analogue BMY25282.
Topics: Animals; Biotransformation; Colonic Neoplasms; Drug Resistance; Humans; Microsomes, Liver; Mitomycin; Mitomycins; Oxidation-Reduction; Rats | 1986 |
Effects of BMY 25282, a mitomycin C analogue, in mitomycin C-resistant human colon cancer cells.
Topics: Animals; Antineoplastic Agents; Biotransformation; Cells, Cultured; Colonic Neoplasms; DNA; Drug Resistance; Female; Humans; In Vitro Techniques; Mice; Mice, Inbred BALB C; Mitomycin; Mitomycins; Neoplasm Transplantation; Rats; Transplantation, Heterologous | 1985 |
Antitumor activity and toxicity in animals of BMY-25282, a new mitomycin derivative.
Topics: Animals; Blood Cell Count; Cells, Cultured; Dose-Response Relationship, Drug; Female; Ferrets; Leukemia, Experimental; Leukocyte Count; Male; Mice; Mitomycin; Mitomycins; Neoplastic Stem Cells; Structure-Activity Relationship | 1985 |
Chemotherapeutic attack of hypoxic tumor cells by the bioreductive alkylating agent mitomycin C.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line; Cell Survival; Cricetinae; Female; Mammary Neoplasms, Experimental; Mesocricetus; Mice; Mice, Inbred BALB C; Mitomycin; Mitomycins; Oxygen; Porfiromycin | 1985 |
Degradation kinetics and mechanism of N6-[(dimethylamino)methylene]mitomycin C in aqueous solutions.
Topics: Buffers; Drug Stability; Hydrogen-Ion Concentration; Kinetics; Mitomycin; Mitomycins; Solutions; Spectrophotometry, Ultraviolet | 1986 |
Mechanism of differential sensitivity of human bladder cancer cells to mitomycin C and its analogue.
Topics: DNA, Neoplasm; Drug Resistance; Humans; Lipid Peroxidation; Mitomycin; Mitomycins; Tumor Cells, Cultured; Tumor Stem Cell Assay; Urinary Bladder Neoplasms | 1994 |
Contrasting molecular cytotoxic mechanisms of mitomycin C and its two analogs, BMY 25282 and BMY 25067, in isolated rat hepatocytes.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Dithiothreitol; Glutathione; Liver; Male; Mitomycin; Mitomycins; Oxidation-Reduction; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Substrate Cycling; Trypan Blue | 1993 |
The importance of DT-diaphorase in mitomycin C resistance in human colon cancer cell lines.
Topics: Aerobiosis; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Survival; Colonic Neoplasms; DNA Topoisomerases, Type II; Drug Resistance; Drug Resistance, Multiple; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Humans; Mitomycin; Mitomycins; NAD(P)H Dehydrogenase (Quinone); Oxidation-Reduction; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1998 |