Compounds > mitomycin
Page last updated: 2024-08-16

mitomycin and methyl methanesulfonate

mitomycin has been researched along with methyl methanesulfonate in 105 studies

Research

Studies (105)

TimeframeStudies, this research(%)All Research%
pre-199019 (18.10)18.7374
1990's40 (38.10)18.2507
2000's30 (28.57)29.6817
2010's14 (13.33)24.3611
2020's2 (1.90)2.80

Authors

AuthorsStudies
Berry, P; Campo, B; Cao, J; Ciaravino, V; Easom, EE; Erve, JCL; Freund, YR; Gamo, FJ; Guo, D; Jacobs, RT; Plattner, JJ; Rosenthal, PJ; Sanz, LM; Zhang, YK1
Badrinarayanan, A; Daw, S; Hasan, MM; Joseph, AM; Le, TBK; Lo, R; Nahar, K; Rahman, KM1
Masek, F; Sedliaková, M1
Tates, AD1
Arcucci, A; De Lorenzo, F; Mallardo, M; Quinto, I; Ruocco, MR; Scala, G1
Inoue, H; Ishii, C; Nakamura, K1
Jüterbock, WR; Messer, W; Quiñones, A1
Bootsma, D; de Wit, J; Hoeijmakers, JH; Masurel, R; Odijk, H; van der Eb, AJ; van Ham, RC; Weeda, G; Westerveld, A1
Huang, XF; Novel, G; Novel, M1
Pattee, PA; Tam, JE1
Agostoni Carbone, ML; Melchioretto, P; Primignani, P; Sora, S1
Ho, IC; Lee, TC; Lin, YC1
Inoue, H; Ishii, C1
Lakdawalla, AA; Netrawali, MS1
English, JD; Vary, PS1
Aeschbacher, HU1
Natarajan, AT; Rotteveel, AH; Schliermann, MG; van Pieterson, J1
Bradley, WG; Munzer, JS; Robison, SH; Tandan, R1
Hama-Inaba, H; Hieda-Shiomi, N; Ito, A; Sato, K; Shiomi, T1
Bertazzoni, U; Izzo, R; Lagomarsini, P; Scovassi, AI; Stefanini, M1
Amsbaugh, SC; DiPaolo, JA; Popescu, NC1
de Vogel, N; Meijers, M; Natarajan, AT; Neuteboom, I; Tates, AD1
Balganesh, M; Setlow, JK1
Egami, N; Shimada, A1
De Caterina, M; De Marinis, E; Rolandi, A1
Neuhäuser-Klaus, A1
Mulder, JA; Venema, G1
Aghamohammadi, Z; Cole, J; Cole, RJ; Henderson, L1
Callander, RD; Graves, RJ; Green, T1
Natarajan, AT; Ribeiro, LR; Salvadori, DM1
Gasiorowski, K; Szyba, K; Urban, J1
Cunha, KS; de Andrade, HH; Gimmler-Luz, MC; Lehmann, M; Reguly, ML; Santos, JH1
Iizawa, Y; Kamiguchi, Y; Mikamo, K; Tateno, H1
Benjamin, DM; He, DM; Hendrickson, EA; Lee, SE; Pulaski, CR; Um, J; Voss, M1
Hayashi, M; Honma, M; Kikuno, T; Mizusawa, H; Ogura, S; Sofuni, T1
Hayashi, M; Honma, M; Matsuoka, A; Sofuni, T; Suzuki, T; Zhang, LS1
Alaoui-Jamali, M; Aubin, R; Batist, G; Bramson, J; Christodoulopoulos, G; McQuillan, A; Panasci, LC1
Azeddoug, H; Reysset, G1
Bronzetti, G; Fiorio, R; Vellosi, R1
Cerutti, H; Ibrahim, HZ; Jagendorf, AT1
Dragonetti, E; Giordano, V; Mallardo, M; Quinto, I; Scala, G1
Baldassarre, F; Dragonetti, E; Mallardo, M; Quinto, I; Ruocco, MR; Scala, G1
Ambulos, NP; Chamnongpol, S; Mongkolsuk, S; Rabibhadana, S; Trempy, JE1
Datta, R; Fine, HA; Manome, Y1
Elhajouji, A; Kirsch-Volders, M; Van Hummelen, P1
Pfuhler, S; Wolf, HU1
Koppen, G; Verschaeve, L1
Aminov, RI; Benno, Y; Nagamine, T; Ogata, K; Sugiura, M; Tajima, K1
Hayashi, M; Honma, M; Sofuni, T1
Kubis, S; Quiñones, A; Wandt, G1
Bootsma, D; de Wit, J; Essers, J; Hendriks, RW; Hoeijmakers, JH; Kanaar, R; Swagemakers, SM; Troelstra, C1
Miyata, M; Murata, S; Seto, S1
Mine, Y; Miyamae, Y; Ohara, K; Sasaki, YF; Zaizen, K1
Furukawa, H; Kawai, K; Matsuo, T; Nakamura, Y; Nakamura, YK; Shimoi, K; Tomita, I1
Petras, ML; Vrzoc, M1
Bärtsch, S; Sengstag, C; Würgler, FE1
Cunha, M; Elhajouji, A; Kirsch-Volders, M1
Johnstone, P; Kohler, S; Moses, RE; Olson, S; Reifsteck, C; Worland, P1
Hama-Inaba, H; Matsushima, T; Mori, M; Muto, M; Ohyama, H; Saitoh, T; Takusagawa, M; Wang, B; Yamada, T1
Bechtold, N; Mengiste, T; Paszkowski, J; Revenkova, E1
Adachi, K; Haresaku, M; Hayashi, M; Masuda, M; Nishikawa, T1
Inoue, H; Masuyama, S; Sakuraba, Y; Tateishi, S; Yamaizumi, M1
Bremer, S; Domke, A; Tenschert, B; Vogel, R1
Graf, U; Lehmann, M; Reguly, ML; Rodrigues De Andrade, HH1
Kaneko, H; Odawara, K; Yamada, T1
Brokos, B; Gasiorowski, K; Leszek, J; Szyba, K1
Geyer, RK; Inoue, T; Maki, CG; Yu, ZK1
Quiñones, A; Rainov, NG1
Ayllón, F; Garcia-Vazquez, E1
Angelis, KJ; Chen, I; Menke, M; Schubert, I1
Ahn, KY; Choi, BK; Kim, CG; Kim, KK; Kim, YC; Koh, JT; Shin, BA1
He, JL; Hu, J; Jin, LF; Zhang, MB; Zheng, W1
Christian, AT; George, JW; Jones, NJ; Lamerdin, JE; Souza, B; Thompson, LH; Yamada, NA1
Garriott, ML; Hoffman, WP; Lee, C; Murphy, GP; Phelps, JB1
Shuai, PQ; Wang, YJ; Zhang, LS2
Gruver, AM; Osborn, JC; Pittman, DL; Smiraldo, PG1
Baohong, W; Deqiang, L; Hongping, D; Jianlin, L; Jiliang, H; Lifen, J; Wei, Z1
Kobayashi, H; Sato, I; Suzuki, T; Tsuda, S1
Deng, HP; He, JL; Jin, LF; Li, QY; Lou, JL; Lu, DQ; Wang, BH; Zheng, W1
Arwert, F; Elghalbzouri-Maghrani, E; Godthelp, BC; Jaspers, NG; Joenje, H; van Buul, PP; van Duijn-Goedhart, A; Zdzienicka, MZ1
Hinz, AK; Hinz, JM; Jones, IM; Mohrenweiser, HW; Nham, PB; Salazar, EP; Tebbs, RS; Thompson, LH; Yamada, NA1
Aguilera-Aguirre, L; Bacsi, A; Boldogh, I; German, P; Kruzel, ML1
de Câmara, JK; de Castro Dantas, TN; de Syllos Cólus, IM; dos Santos, FV; Maciel, MA; Poersch, A1
Baker, MD; Lee, SA1
Alonso, JC; Carrasco, B; Cozar, MC; Sanchez, H1
Ennis, DG; Lantsheer, L; Mertens, K; Samuel, JE1
Aardema, MJ; Barnett, B; Curren, RD; Hu, T; Kaluzhny, Y; Karetsky, V; Klausner, M; Mun, GC; Wilt, N1
Cao, Z; Julin, DA1
Carr, AM; Dyjankiewicz, A; Dziadkowiec, D; Garcia, V; Karpiński, P; Petters, E; Watson, A1
Chang, Y; Chen, G; Gong, L; Li, X; Wu, C; Yuan, W; Zhang, Q1
Elhajouji, A; Kirsch-Volders, M; Lukamowicz, M; Suter, W; Woodward, K1
Forterre, P; Fujikane, R; Ishino, S; Ishino, Y1
Berghella, L; Cossu, G; Innocenzi, A; Latella, L; Marullo, F; Messina, G; Poizat, C; Puri, PL; Shu, CW; Simonatto, M; Wang, JY1
Karmakar, P; Samanta, S1
Kuehner, S; Linsenmeyer, R; Schütz, P; Speit, G1
Cao, K; Chen, DB; Li, L; Lin, C; Nie, CL; Wan, Y; Wei, YQ; Yuan, Z; Zhao, XY1
Honma, M; Kimura, A; Miyata, A1
Chapman, KE; Doak, SH; Jenkins, GJ; Pfuhler, S; Thomas, AD; Wills, JW1
Chocian, K; Clatworthy, M; Doak, S; Doherty, AT; Jenkins, G; Molloy, J; O'Donovan, M; Wilson, A1
Adachi, N; Grúz, P; Honma, M; Kanemaru, Y; Matsumoto, K; Niimi, N; Nohmi, T; Suzuki, T1
Abraham, SK; Hintzsche, H; Khandelwal, N; Stopper, H1
Costa, C; Fernández-Bertólez, N; Laffon, B; Pásaro, E; Valdiglesias, V1
Alonso, JC; Ayora, S; Graumann, PL; Hernández-Tamayo, R; Lucena, D; Romero, H; Rösch, TC1
Helbling, FR; Huber, A; McHugh, D; Smart, DJ; Vanscheeuwijck, P; Verardo, M1

Other Studies

105 other study(ies) available for mitomycin and methyl methanesulfonate

ArticleYear
Benzoxaborole Antimalarial Agents. Part 5. Lead Optimization of Novel Amide Pyrazinyloxy Benzoxaboroles and Identification of a Preclinical Candidate.
    Journal of medicinal chemistry, 2017, 07-13, Volume: 60, Issue:13

    Topics: Amides; Animals; Antimalarials; Boron Compounds; Dogs; Female; Humans; Malaria; Malaria, Falciparum; Male; Mice; Plasmodium berghei; Plasmodium falciparum; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

2017
Mechanistic insight into the repair of C8-linked pyrrolobenzodiazepine monomer-mediated DNA damage.
    RSC medicinal chemistry, 2022, Dec-14, Volume: 13, Issue:12

    Topics:

2022
Inducible stable DNA replication in Escherichia coli uvr+ and uvr- cells, treated with genotoxic chemicals.
    Mutation research, 1992, Volume: 281, Issue:1

    Topics: 4-Nitroquinoline-1-oxide; 4-Quinolones; Acrylates; Anti-Infective Agents; Chloramphenicol; DNA Replication; Escherichia coli; Furans; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methylnitrosourea; Mitomycin; Mutagens; Nalidixic Acid; Nitro Compounds; Nitrofurans

1992
Validation studies with the micronucleus test for early spermatids of rats. A tool for detecting clastogenicity of chemicals in differentiating spermatogonia and spermatocytes.
    Mutagenesis, 1992, Volume: 7, Issue:6

    Topics: Animals; Cyclophosphamide; Ethylnitrosourea; Evaluation Studies as Topic; Male; Methyl Methanesulfonate; Mice; Micronucleus Tests; Mitomycin; Mutagens; Rats; Rats, Wistar; Spermatids; Spermatocytes; Spermatogonia; Vincristine

1992
Spontaneous and mutagen-mediated amplification of a neo gene integrated at different genomic sites in rat 2 fibroblasts.
    Carcinogenesis, 1992, Volume: 13, Issue:3

    Topics: Animals; Blotting, Southern; Drug Resistance; Fibroblasts; Gene Amplification; Gene Expression Regulation, Neoplastic; Gentamicins; Methyl Methanesulfonate; Mitomycin; Rats; Transfection

1992
A novel phenotype of an excision-repair mutant in Neurospora crassa: mutagen sensitivity of the mus-18 mutant is specific to UV.
    Molecular & general genetics : MGG, 1991, Volume: 228, Issue:1-2

    Topics: 4-Nitroquinoline-1-oxide; Alkylating Agents; Chromosome Mapping; DNA Damage; DNA Repair; DNA, Bacterial; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electrophoresis, Agar Gel; Epistasis, Genetic; Gamma Rays; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Mutation; Neurospora crassa; Phenotype; Ultraviolet Rays

1991
Expression of the dnaA gene of Escherichia coli is inducible by DNA damage.
    Molecular & general genetics : MGG, 1991, Volume: 227, Issue:1

    Topics: Bacterial Proteins; Cloning, Molecular; DNA Damage; DNA-Binding Proteins; DNA, Bacterial; Escherichia coli; Galactokinase; Gene Expression; Genes, Bacterial; Kinetics; Methyl Methanesulfonate; Mitomycin; Mitomycins; Promoter Regions, Genetic; Recombinant Fusion Proteins

1991
Molecular cloning and biological characterization of the human excision repair gene ERCC-3.
    Molecular and cellular biology, 1990, Volume: 10, Issue:6

    Topics: Alkylating Agents; Animals; Blotting, Southern; Cell Line; Cloning, Molecular; DNA; DNA Repair; DNA Replication; Genes; Genomic Library; Humans; Kinetics; Methyl Methanesulfonate; Mitomycin; Mitomycins; Mutation; Nucleic Acid Hybridization; Restriction Mapping; Transfection; Ultraviolet Rays

1990
Cloning of a chromosomal fragment from Lactococcus lactis subsp. lactis partially complementing Escherichia coli recA functions.
    FEMS microbiology letters, 1990, Volume: 60, Issue:3

    Topics: Bacteriophage lambda; Chromosomes, Bacterial; Cloning, Molecular; DNA, Bacterial; Drug Resistance; Escherichia coli; Genes, Bacterial; Genetic Complementation Test; Genomic Library; Lactococcus lactis; Methyl Methanesulfonate; Mitomycin; Mitomycins; Mutation; Rec A Recombinases; Recombinant Proteins; Restriction Mapping; Ultraviolet Rays

1990
Characterization and genetic mapping of a mutation affecting apurinic endonuclease activity in Staphylococcus aureus.
    Journal of bacteriology, 1986, Volume: 168, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; Chromosome Mapping; Chromosomes, Bacterial; Deoxyribonuclease IV (Phage T4-Induced); DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; Endodeoxyribonucleases; Ethyl Methanesulfonate; Genes, Bacterial; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Mutation; Nitrous Acid; Recombination, Genetic; Staphylococcus aureus; Ultraviolet Rays

1986
Caffeine interactions with methyl methanesulphonate, hycanthone, benlate, and cadmium chloride in chromosomal meiotic segregation of Saccharomyces cerevisiae.
    Mutation research, 1988, Volume: 201, Issue:1

    Topics: Benomyl; Bleomycin; Cadmium; Cadmium Chloride; Caffeine; Chromosomes; Diploidy; Distamycins; Drug Interactions; Drug Synergism; Hycanthone; Meiosis; Methyl Methanesulfonate; Mitomycin; Mitomycins; Saccharomyces cerevisiae

1988
Ethanol and acetaldehyde potentiate the clastogenicity of ultraviolet light, methyl methanesulfonate, mitomycin C and bleomycin in Chinese hamster ovary cells.
    Mutation research, 1989, Volume: 216, Issue:2

    Topics: Acetaldehyde; Animals; Bleomycin; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Drug Synergism; Ethanol; Female; Methyl Methanesulfonate; Mitomycin; Mitomycins; Mutagens; Ovary; Ultraviolet Rays

1989
Epistasis, photoreactivation and mutagen sensitivity of DNA repair mutants upr-1 and mus-26 in Neurospora crassa.
    Mutation research, 1989, Volume: 218, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; Aminacrine; DNA Repair; Dose-Response Relationship, Radiation; Gamma Rays; Genotype; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Mutagens; Mutation; Neurospora; Neurospora crassa; Nitrogen Mustard Compounds; Ultraviolet Rays

1989
Mutagenicity, comutagenicity, and antimutagenicity of erythrosine (FD and C red 3), a food dye, in the Ames/Salmonella assay.
    Mutation research, 1988, Volume: 204, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; Animals; Azides; Benzo(a)pyrene; Carbolines; Cecum; DNA Damage; DNA Repair; Drug Interactions; Erythrosine; Ethidium; Fluoresceins; Food Coloring Agents; Harmine; Male; Methyl Methanesulfonate; Microsomes, Liver; Mitomycin; Mitomycins; Mutation; Rats; Rats, Inbred Strains; Salmonella typhimurium; Sodium Azide

1988
Isolation of recombination-defective and UV-sensitive mutants of Bacillus megaterium.
    Journal of bacteriology, 1986, Volume: 165, Issue:1

    Topics: Bacillus megaterium; Gamma Rays; Methyl Methanesulfonate; Mitomycin; Mitomycins; Mutation; Recombination, Genetic; Transduction, Genetic; Ultraviolet Rays

1986
Rates of micronuclei induction in different mouse strains.
    Mutation research, 1986, Volume: 164, Issue:2

    Topics: Animals; Cell Nucleus; Dose-Response Relationship, Drug; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mice; Mice, Inbred Strains; Mitomycin; Mitomycins; Mutagenicity Tests; Species Specificity

1986
Influence of incorporated 5-bromodeoxyuridine on the frequencies of spontaneous and induced sister-chromatid exchanges, detected by immunological methods.
    Mutation research, 1986, Volume: 163, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Bromodeoxyuridine; Cell Line; Cricetinae; Dose-Response Relationship, Drug; Methyl Methanesulfonate; Mitomycin; Mitomycins; Sister Chromatid Exchange

1986
Deficient DNA repair in amyotrophic lateral sclerosis cells.
    Journal of the neurological sciences, 1987, Volume: 79, Issue:1-2

    Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Cell Survival; Cells, Cultured; DNA; DNA Repair; Fibroblasts; Humans; Methyl Methanesulfonate; Middle Aged; Mitomycin; Mitomycins; Ultraviolet Rays; X-Rays

1987
Mutagen detection with a mouse line containing 3 distinct mutations conferring sensitivity.
    Mutation research, 1987, Volume: 182, Issue:4

    Topics: 4-Nitroquinoline-1-oxide; Animals; Cell Line; Cross-Linking Reagents; DNA Repair; Drug Resistance; Leukemia L5178; Methyl Methanesulfonate; Mice; Mitomycin; Mitomycins; Mutagenicity Tests; Mutation; Radiation Tolerance; Ultraviolet Rays; X-Rays

1987
Response of mammalian ADP-ribosyl transferase to lymphocyte stimulation, mutagen treatment and cell cycling.
    Carcinogenesis, 1987, Volume: 8, Issue:9

    Topics: Cell Cycle; DNA Damage; HeLa Cells; Humans; Lymphocyte Activation; Lymphocytes; Methyl Methanesulfonate; Mitomycin; Mitomycins; Mutagens; Phytohemagglutinins; Poly(ADP-ribose) Polymerases; Sulfuric Acid Esters

1987
Persistence of sister chromatid exchanges and in vitro morphological transformation of Syrian hamster fetal cells by chemical and physical carcinogens.
    Carcinogenesis, 1985, Volume: 6, Issue:11

    Topics: Animals; Benzo(a)pyrene; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; DNA; Fetus; Mesocricetus; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Sister Chromatid Exchange

1985
Induction of sister-chromatid exchanges (SCEs) and chromosomal aberrations by mitomycin C and methyl methanesulfonate in Chinese hamster ovary cells. An evaluation of methodology for detection of SCEs and of persistent DNA lesions towards the frequencies
    Mutation research, 1983, Volume: 121, Issue:3-4

    Topics: Animals; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Crossing Over, Genetic; Female; Methods; Methyl Methanesulfonate; Mitomycin; Mitomycins; Ovary; Sister Chromatid Exchange

1983
Prophage induction in Haemophilus influenzae and its relationship to mutation by chemical and physical agents.
    Mutation research, 1984, Volume: 125, Issue:1

    Topics: Bacteriophages; Ethyl Methanesulfonate; Haemophilus influenzae; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Mutagens; Mutation; Ultraviolet Rays; Virus Activation

1984
Dominant lethal mutations induced by MMS and mitomycin C in the fish Oryzias latipes.
    Mutation research, 1984, Volume: 125, Issue:2

    Topics: Animals; Antibiotics, Antineoplastic; Female; Fertilization; Fishes; Genes, Dominant; Genes, Lethal; Male; Methyl Methanesulfonate; Mitomycin; Mitomycins; Mutagens; Mutation; Ovum; Reproduction; Spermatozoa

1984
Dithiocarbamate pesticides: activity of Propineb in the micronucleus test in mice.
    Mutation research, 1984, Volume: 135, Issue:3

    Topics: Animals; Antibiotics, Antineoplastic; Cell Nucleus; Erythrocytes; Female; Male; Methyl Methanesulfonate; Mice; Mitomycin; Mitomycins; Mutagenicity Tests; Mutagens; Mutation; Thiocarbamates; Thiourea; Zineb

1984
An approach towards to standardization of the mammalian spot test.
    Archives of toxicology, 1981, Volume: 48, Issue:4

    Topics: Animals; Embryo, Mammalian; Female; Genotype; Methyl Methanesulfonate; Mice; Mitomycin; Mitomycins; Mutagenicity Tests; Mutagens; Pregnancy; Procarbazine; Time Factors

1981
Isolation and partial characterization of Bacillus subtilis mutants impaired in DNA entry.
    Journal of bacteriology, 1982, Volume: 150, Issue:1

    Topics: Bacillus subtilis; DNA, Bacterial; Edetic Acid; Methyl Methanesulfonate; Mitomycin; Mitomycins; Mutation; Transduction, Genetic; Transformation, Genetic; Ultraviolet Rays

1982
Short-term tests for transplacentally active carcinogens. Multiple-dose regimes in the transplacental micronucleus test.
    Mutation research, 1982, Volume: 105, Issue:1-2

    Topics: Antibiotics, Antineoplastic; Carcinogens; Cell Cycle; Female; Fetus; Humans; Liver; Maternal-Fetal Exchange; Methyl Methanesulfonate; Mitomycin; Mitomycins; Placenta; Pregnancy

1982
The role of formaldehyde and S-chloromethylglutathione in the bacterial mutagenicity of methylene chloride.
    Mutation research, 1994, Volume: 320, Issue:3

    Topics: Animals; Biotransformation; Escherichia coli; Ethylene Dibromide; Formaldehyde; Glutathione; Glutathione Transferase; Male; Methyl Methanesulfonate; Methylene Chloride; Mice; Mitomycin; Mutagenicity Tests; Nitroso Compounds; Rats; Salmonella typhimurium

1994
Effect of beta-carotene on clastogenic effects of mitomycin C, methyl methanesulphonate and bleomycin in Chinese hamster ovary cells.
    Mutagenesis, 1994, Volume: 9, Issue:1

    Topics: Animals; Antimutagenic Agents; beta Carotene; Bleomycin; Carotenoids; CHO Cells; Cricetinae; Methyl Methanesulfonate; Micronuclei, Chromosome-Defective; Mitomycin; Mutagenicity Tests

1994
Todralazine influence upon the mutagenicity of some direct- and indirect-acting mutagens.
    Mutation research, 1994, Volume: 324, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Aminacrine; Antimutagenic Agents; Azides; Benzo(a)pyrene; Biotransformation; Daunorubicin; Dose-Response Relationship, Drug; Methyl Methanesulfonate; Methylcholanthrene; Microsomes, Liver; Mitomycin; Mutagenicity Tests; Mutagens; Salmonella typhimurium; Sodium Azide; Todralazine

1994
Co-mutagenic effect of tannic acid on ring-X chromosome loss induced by mitomycin C in sperm cells of Drosophila melanogaster.
    Mutation research, 1994, Jul-16, Volume: 308, Issue:2

    Topics: Animals; Antimutagenic Agents; Chi-Square Distribution; Chromosome Deletion; DNA Repair; Drosophila melanogaster; Drug Synergism; Female; Hydrolyzable Tannins; Male; Methyl Methanesulfonate; Mitomycin; Mutagenicity Tests; Mutagens; Ring Chromosomes; Spermatozoa; X Chromosome

1994
Chromosome analysis of human spermatozoa exposed to antineoplastic agents in vitro.
    Mutation research, 1995, Volume: 326, Issue:2

    Topics: Animals; Antineoplastic Agents; Bleomycin; Cattle; Chromosome Aberrations; Cricetinae; Cyclophosphamide; Daunorubicin; Female; Fertilization in Vitro; Humans; Male; Methyl Methanesulfonate; Mitomycin; Mutagens; Oocytes; Spermatozoa; Triethylenemelamine

1995
Isolation of mammalian cell mutants that are X-ray sensitive, impaired in DNA double-strand break repair and defective for V(D)J recombination.
    Mutation research, 1995, Volume: 336, Issue:3

    Topics: Animals; Base Sequence; Bleomycin; Cell Line; Cell Transformation, Viral; Cricetinae; Cricetulus; DNA Damage; DNA Repair; Dose-Response Relationship, Radiation; Electrophoresis, Gel, Pulsed-Field; Gene Rearrangement; Genes, Immunoglobulin; Lung; Methyl Methanesulfonate; Mitomycin; Molecular Sequence Data; Moloney murine leukemia virus; Mutagenesis, Insertional; Oligonucleotide Probes; Radiation Tolerance; Receptors, Antigen; Recombination, Genetic

1995
DNA fingerprint analysis in chemically mutagenized Chinese hamster lung cells.
    Mutation research, 1995, Volume: 338, Issue:1-6

    Topics: 2-Acetylaminofluorene; Animals; Cell Line; Cricetinae; Cricetulus; Cyclophosphamide; DNA Fingerprinting; DNA Probes; DNA, Satellite; Furylfuramide; Lung; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mitomycin; Mutagenesis; Mutagens

1995
A comparative study of TK6 human lymphoblastoid and L5178Y mouse lymphoma cell lines in the in vitro micronucleus test.
    Mutation research, 1995, Volume: 347, Issue:3-4

    Topics: Animals; B-Lymphocytes; Cell Line; Cell Survival; Demecolcine; Ethyl Methanesulfonate; Humans; Leukemia L5178; Lymphoma; Methyl Methanesulfonate; Mice; Micronucleus Tests; Mitomycin; Mutagens; Tumor Cells, Cultured; Vincristine; X-Rays

1995
Nitrogen mustard drug resistant B-cell chronic lymphocytic leukemia as an in vivo model for crosslinking agent resistance.
    Mutation research, 1995, Volume: 336, Issue:3

    Topics: B-Lymphocytes; Chlorambucil; Cisplatin; Cross-Linking Reagents; DNA Adducts; DNA Damage; DNA Repair; DNA, Neoplasm; Drug Resistance; Humans; Inactivation, Metabolic; Leukemia, Lymphocytic, Chronic, B-Cell; Melphalan; Methyl Methanesulfonate; Mitomycin; Nitrogen Mustard Compounds; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

1995
Cloning and sequencing of a chromosomal fragment from Clostridium acetobutylicum strain ABKn8 conferring chemical-damaging agents and UV resistance to E. coli recA strains.
    Current microbiology, 1994, Volume: 29, Issue:4

    Topics: Amino Acid Sequence; Bacteriophage lambda; Base Sequence; Calcium-Binding Proteins; Cell-Free System; Chromosomes, Bacterial; Cloning, Molecular; Clostridium; Drug Resistance, Microbial; Escherichia coli; Genetic Complementation Test; Isomerases; Methyl Methanesulfonate; Mitomycin; Molecular Sequence Data; Molecular Weight; Open Reading Frames; Radiation Tolerance; Rec A Recombinases; Recombinant Fusion Proteins; Sequence Homology; Sequence Homology, Amino Acid; SOS Response, Genetics; Sulfur-Sulfur Bond Isomerases; Ultraviolet Rays; Virus Activation

1994
Effects of spermine on formation of HGPRT- mutants induced by ethylmethanesulfonate, methylmethanesulfonate, and mitomycin C in V79 Chinese hamster cells.
    Environmental and molecular mutagenesis, 1994, Volume: 23, Issue:4

    Topics: Alkylation; Animals; Antimutagenic Agents; Binding, Competitive; Cells, Cultured; Cricetinae; Cricetulus; Ethyl Methanesulfonate; Glutathione; Glutathione Transferase; Hypoxanthine Phosphoribosyltransferase; Lung; Methyl Methanesulfonate; Mitomycin; Mutagenesis; Mutagenicity Tests; Mutagens; Spermine

1994
Treatment of pea (Pisum sativum L.) protoplasts with DNA-damaging agents induces a 39-kilodalton chloroplast protein immunologically related to Escherichia coli RecA.
    Plant physiology, 1993, Volume: 102, Issue:1

    Topics: Chloroplasts; DNA Damage; DNA Repair; DNA, Single-Stranded; Escherichia coli; Fabaceae; Immunochemistry; Methyl Methanesulfonate; Mitomycin; Nalidixic Acid; Plant Proteins; Plants, Medicinal; Protoplasts; Rec A Recombinases

1993
DNA damaging agents increase the stability of interleukin-1 alpha, interleukin-1 beta, and interleukin-6 transcripts and the production of the relative proteins.
    The Journal of biological chemistry, 1994, May-27, Volume: 269, Issue:21

    Topics: Carcinogens; Cells, Cultured; DNA Damage; Ethyl Methanesulfonate; Gene Expression Regulation; Humans; Interleukin-1; Interleukin-6; Methyl Methanesulfonate; Mitomycin; Monocytes; RNA, Messenger; Transcription, Genetic

1994
The human immunodeficiency virus type 1 long terminal repeat is activated by monofunctional and bifunctional DNA alkylating agents in human lymphocytes.
    The Journal of biological chemistry, 1993, Dec-15, Volume: 268, Issue:35

    Topics: Alkylating Agents; Base Sequence; Cell Line; Chloramphenicol O-Acetyltransferase; Ethyl Methanesulfonate; HIV Long Terminal Repeat; HIV-1; Humans; Lymphocytes; Methyl Methanesulfonate; Mitomycin; Molecular Sequence Data; Mutagens; NF-kappa B; Nuclear Proteins; Sp1 Transcription Factor; Virus Activation

1993
Isolation and expression in Escherichia coli of a Xanthomonas oryzae recA-like gene.
    Gene, 1993, Sep-30, Volume: 132, Issue:1

    Topics: Bacteriophage lambda; Blotting, Southern; Blotting, Western; Cloning, Molecular; Escherichia coli; Genetic Complementation Test; Methyl Methanesulfonate; Mitomycin; Rec A Recombinases; Species Specificity; Viral Plaque Assay; Xanthomonas

1993
Early response gene induction following DNA damage in astrocytoma cell lines.
    Biochemical pharmacology, 1993, Apr-22, Volume: 45, Issue:8

    Topics: Astrocytoma; Cell Death; DNA Damage; Gene Expression; Genes, fos; Genes, jun; Hematopoietic Stem Cells; Humans; Methyl Methanesulfonate; Mitomycin; RNA, Messenger; Time Factors; Transcription, Genetic; Tumor Cells, Cultured

1993
Indications for a threshold of chemically-induced aneuploidy in vitro in human lymphocytes.
    Environmental and molecular mutagenesis, 1995, Volume: 26, Issue:4

    Topics: Adult; Aneuploidy; Benzimidazoles; Carbamates; Cell Division; Cell Survival; Cells, Cultured; Centromere; Colchicine; Flow Cytometry; Humans; In Situ Hybridization, Fluorescence; Lymphocytes; Mebendazole; Methyl Methanesulfonate; Micronucleus Tests; Mitomycin; Mutagens; Nocodazole

1995
Detection of DNA-crosslinking agents with the alkaline comet assay.
    Environmental and molecular mutagenesis, 1996, Volume: 27, Issue:3

    Topics: Adult; Cell Survival; Cisplatin; Cross-Linking Reagents; DNA; DNA Damage; Drug Synergism; Electrophoresis, Agar Gel; Evaluation Studies as Topic; Formaldehyde; Humans; Hydrogen-Ion Concentration; Lymphocytes; Male; Methyl Methanesulfonate; Methylurea Compounds; Mitomycin; Urea

1996
The alkaline comet test on plant cells: a new genotoxicity test for DNA strand breaks in Vicia faba root cells.
    Mutation research, 1996, Aug-08, Volume: 360, Issue:3

    Topics: Cadmium; Cadmium Chloride; Chlorides; Chromium Compounds; Cycloheximide; DNA Damage; Electrophoresis, Agar Gel; Ethyl Methanesulfonate; Fabaceae; Genetic Techniques; Methyl Methanesulfonate; Mitomycin; Models, Statistical; Mutagenicity Tests; Plant Roots; Plants, Medicinal; Protein Synthesis Inhibitors; Software

1996
Cloning, sequencing and complementation analysis of the recA gene from Prevotella ruminicola.
    FEMS microbiology letters, 1996, Oct-15, Volume: 144, Issue:1

    Topics: Amino Acid Sequence; Cloning, Molecular; Escherichia coli; Genes, Bacterial; Genetic Complementation Test; Methyl Methanesulfonate; Mitomycin; Molecular Sequence Data; Mutagens; Prevotella; Rec A Recombinases; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Ultraviolet Rays

1996
Cytotoxic and mutagenic responses to X-rays and chemical mutagens in normal and p53-mutated human lymphoblastoid cells.
    Mutation research, 1997, Mar-04, Volume: 374, Issue:1

    Topics: Cell Line; Chromosome Breakage; Chromosome Deletion; DNA Fingerprinting; Ethyl Methanesulfonate; Genes, p53; Humans; Lymphocytes; Methyl Methanesulfonate; Mitomycin; Mutagens; X-Rays

1997
Treatment with DNA-damaging agents increases expression of polA'-'lacZ gene fusions in Escherichia coli K-12.
    Molecular & general genetics : MGG, 1997, Mar-18, Volume: 254, Issue:1

    Topics: 4-Nitroquinoline-1-oxide; DNA Damage; DNA, Bacterial; Escherichia coli; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Methyl Methanesulfonate; Mitomycin; Promoter Regions, Genetic; Recombinant Fusion Proteins; RNA, Bacterial; RNA, Messenger; SOS Response, Genetics

1997
Disruption of mouse RAD54 reduces ionizing radiation resistance and homologous recombination.
    Cell, 1997, Apr-18, Volume: 89, Issue:2

    Topics: Alkylating Agents; Animals; DNA Damage; DNA Helicases; DNA Repair; DNA Repair Enzymes; DNA, Recombinant; Fungal Proteins; Gamma Rays; Gene Targeting; Genes, Immunoglobulin; Immunoglobulin Class Switching; Methyl Methanesulfonate; Mice; Mice, Mutant Strains; Mitomycin; Phenotype; Radiation Tolerance; Recombination, Genetic; Saccharomyces cerevisiae Proteins; Stem Cells; Ultraviolet Rays

1997
Characterization of dnaA gene expression in Mycoplasma capricolum.
    FEMS microbiology letters, 1997, May-15, Volume: 150, Issue:2

    Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; DNA-Binding Proteins; DNA, Bacterial; Gene Expression Regulation, Bacterial; Genes, Bacterial; Methyl Methanesulfonate; Mitomycin; Molecular Sequence Data; Mycoplasma; Nucleic Acid Synthesis Inhibitors; Recombinant Fusion Proteins; Transcription, Genetic

1997
Detection of DNA lesions induced by chemical mutagens by the single cell gel electrophoresis (Comet) assay. 1. Relationship between the onset of DNA damage and the characteristics of mutagens.
    Mutation research, 1997, Sep-18, Volume: 393, Issue:1-2

    Topics: Animals; Bleomycin; Cross-Linking Reagents; DNA Damage; Electrophoresis; Leukemia L5178; Mercaptopurine; Methyl Methanesulfonate; Methylnitrosourea; Mice; Mitomycin; Mutagenicity Tests; Mutagens; Nucleic Acid Synthesis Inhibitors; Time Factors; Tumor Cells, Cultured; Ultraviolet Rays; X-Rays

1997
Suppressing effects of S-methyl methanethiosulfonate and diphenyl disulfide on mitomycin C-induced somatic mutation and recombination in Drosophila melanogaster and micronuclei in mice.
    Mutation research, 1997, Volume: 385, Issue:1

    Topics: Animals; Antimutagenic Agents; Disulfides; Drosophila melanogaster; Male; Methyl Methanesulfonate; Mice; Mice, Inbred ICR; Micronucleus Tests; Mitomycin; Mutagens; Mutation; Recombination, Genetic; Reticulocytes; Wings, Animal

1997
Comparison of alkaline single cell gel (Comet) and peripheral blood micronucleus assays in detecting DNA damage caused by direct and indirect acting mutagens.
    Mutation research, 1997, Nov-19, Volume: 381, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Cyclophosphamide; DNA Damage; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Lymphocytes; Male; Methyl Methanesulfonate; Methylnitrosourea; Mice; Mice, Inbred Strains; Micronucleus Tests; Mitomycin; Mutagenicity Tests; Mutagens; Sensitivity and Specificity

1997
A genetic system to detect mitotic recombination between repeated chromosomal sequences in Drosophila Schneider line 2 cells.
    Mutation research, 1997, Dec-05, Volume: 395, Issue:1

    Topics: Animals; beta-Galactosidase; Cells, Cultured; Chromosomes; Drosophila melanogaster; Drug Resistance; Escherichia coli; Ethyl Methanesulfonate; Flow Cytometry; Genes, Reporter; Gentamicins; Methyl Methanesulfonate; Mitomycin; Mitosis; Mutagenicity Tests; Mutagens; Polymerase Chain Reaction; Recombination, Genetic; Repetitive Sequences, Nucleic Acid; Transgenes

1997
Spindle poisons can induce polyploidy by mitotic slippage and micronucleate mononucleates in the cytokinesis-block assay.
    Mutagenesis, 1998, Volume: 13, Issue:2

    Topics: Benzimidazoles; Carbamates; Colchicine; Female; Humans; Leukocyte Count; Leukocytes, Mononuclear; Male; Mebendazole; Methyl Methanesulfonate; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mitomycin; Mutagens; Nocodazole; Polyploidy; Spindle Apparatus

1998
Fanconi anemia group A and D cell lines respond normally to inhibitors of cell cycle regulation.
    Somatic cell and molecular genetics, 1997, Volume: 23, Issue:6

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Caffeine; Cell Cycle; Cells, Cultured; Central Nervous System Stimulants; Chromosome Breakage; Cross-Linking Reagents; DNA Adducts; Enzyme Inhibitors; Fanconi Anemia; Humans; Hydrogen Peroxide; Hydroxyurea; Methyl Methanesulfonate; Mitomycin; Oxidants

1997
Radio-sensitive murine thymoma cell line 3SB: characterization of its apoptosis-resistant variants induced by repeated X-irradiation.
    Mutation research, 1998, Jul-17, Volume: 403, Issue:1-2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Daunorubicin; Drug Resistance; Genetic Variation; Methyl Methanesulfonate; Mice; Mitomycin; Mutagens; Radiation Tolerance; Sphingosine; Thymoma; Thymus Neoplasms; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1998
An SMC-like protein is required for efficient homologous recombination in Arabidopsis.
    The EMBO journal, 1999, Aug-16, Volume: 18, Issue:16

    Topics: Amino Acid Sequence; Animals; Arabidopsis; Arabidopsis Proteins; Base Sequence; Chromosome Mapping; DNA Damage; DNA, Plant; Genes, Plant; Glucuronidase; Methyl Methanesulfonate; Mitomycin; Molecular Sequence Data; Mutagens; Plant Proteins; Recombination, Genetic; Sequence Homology, Amino Acid; Ultraviolet Rays

1999
Study of a rat skin in vivo micronucleus test: data generated by mitomycin C and methyl methanesulfonate.
    Mutation research, 1999, Jul-21, Volume: 444, Issue:1

    Topics: Acridine Orange; Animals; Dose-Response Relationship, Drug; Fluorescent Dyes; Male; Methyl Methanesulfonate; Micronucleus Tests; Mitomycin; Models, Biological; Mutagens; Rats; Rats, Sprague-Dawley; Skin

1999
Dysfunction of human Rad18 results in defective postreplication repair and hypersensitivity to multiple mutagens.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Jul-05, Volume: 97, Issue:14

    Topics: Amino Acid Sequence; Chromosome Mapping; Chromosomes, Human, Pair 3; DNA Repair; DNA Replication; DNA-Binding Proteins; Expressed Sequence Tags; Gene Library; Humans; Ligases; Methyl Methanesulfonate; Mitomycin; Molecular Sequence Data; Mutagens; Polymerase Chain Reaction; Protein Binding; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Two-Hybrid System Techniques; Ubiquitin-Conjugating Enzymes; Ultraviolet Rays

2000
In vitro germ cell models for the detection of fertility impairment.
    Andrologia, 2000, Volume: 32, Issue:4-5

    Topics: Animals; Cell Differentiation; Cell Division; DNA Damage; Drug Evaluation, Preclinical; Ethylnitrosourea; Fertility; Germ Cells; Methyl Methanesulfonate; Mice; Mitomycin; Models, Biological; Mutagens; Sister Chromatid Exchange; Stem Cells; Teratocarcinoma; Tumor Cells, Cultured

2000
Interference of tannic acid on the genotoxicity of mitomycin C, methylmethanesulfonate, and nitrogen mustard in somatic cells of Drosophila melanogaster.
    Environmental and molecular mutagenesis, 2000, Volume: 36, Issue:3

    Topics: Animals; Crosses, Genetic; Drosophila melanogaster; Female; Hydrolyzable Tannins; Larva; Male; Mechlorethamine; Methyl Methanesulfonate; Mitomycin; Mutagenicity Tests; Mutagens; Oviposition; Wings, Animal

2000
Concurrent detection of gene mutations and chromosome aberrations induced by five chemicals in a CHL/IU cell line incorporating a gpt shuttle vector.
    Mutation research, 2000, Nov-20, Volume: 471, Issue:1-2

    Topics: Animals; Bacterial Proteins; Cell Survival; Cells, Cultured; Chromosome Aberrations; Cricetinae; Cricetulus; Escherichia coli; Escherichia coli Proteins; Ethylnitrosourea; Genetic Vectors; Methyl Methanesulfonate; Mitomycin; Mutagenesis; Mutagens; Pentosyltransferases; Proteins; Rosaniline Dyes; Toluidines; Vincristine

2000
Antimutagenic activity of fluphenazine in short-term tests.
    Mutagenesis, 2001, Volume: 16, Issue:1

    Topics: Adult; Antimutagenic Agents; Benzo(a)pyrene; Cells, Cultured; Daunorubicin; Fluphenazine; Humans; Lymphocytes; Male; Methyl Methanesulfonate; Micronucleus Tests; Middle Aged; Mitomycin; Mutagenicity Tests; Mutagens; Sister Chromatid Exchange

2001
Downregulation of MDM2 stabilizes p53 by inhibiting p53 ubiquitination in response to specific alkylating agents.
    FEBS letters, 2001, Feb-16, Volume: 490, Issue:3

    Topics: Alkylating Agents; DNA Damage; Down-Regulation; Humans; Methyl Methanesulfonate; Mitomycin; Mutation; Nuclear Proteins; Phosphorylation; Phosphoserine; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; RNA, Messenger; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Ubiquitins; Ultraviolet Rays

2001
Identification of genotoxic stress in human cells by fluorescent monitoring of p53 expression.
    Mutation research, 2001, Jul-25, Volume: 494, Issue:1-2

    Topics: 4-Nitroquinoline-1-oxide; Carcinogenicity Tests; DNA Damage; Doxorubicin; Gene Expression; Genes, Reporter; Green Fluorescent Proteins; Humans; Luminescent Proteins; Methyl Methanesulfonate; Mitomycin; Mutagenicity Tests; Tumor Suppressor Protein p53

2001
Micronuclei and other nuclear lesions as genotoxicity indicators in rainbow trout Oncorhynchus mykiss.
    Ecotoxicology and environmental safety, 2001, Volume: 49, Issue:3

    Topics: Acrylamide; Animals; Cell Nucleus; Colchicine; Cyclophosphamide; Erythrocytes; Injections, Intraperitoneal; Methyl Methanesulfonate; Methylnitrosourea; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mitomycin; Mutagens; Oncorhynchus mykiss

2001
DNA damage and repair in Arabidopsis thaliana as measured by the comet assay after treatment with different classes of genotoxins.
    Mutation research, 2001, Jun-27, Volume: 493, Issue:1-2

    Topics: Alkylating Agents; Arabidopsis; Bleomycin; Comet Assay; DNA Damage; DNA Repair; Herbicides; Maleic Hydrazide; Methyl Methanesulfonate; Methylnitrosourea; Mitomycin; Mutagens; Radiation-Sensitizing Agents

2001
An antisense construct of full-length human RAD50 cDNA confers sensitivity to ionizing radiation and alkylating agents on human cell lines.
    Radiation research, 2002, Volume: 157, Issue:1

    Topics: Acid Anhydride Hydrolases; Alkylating Agents; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Cell Line; DNA Damage; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; DNA, Complementary; DNA, Neoplasm; Gamma Rays; Humans; Kidney; Liver Neoplasms; Methyl Methanesulfonate; Mitomycin; MRE11 Homologue Protein; Oligodeoxyribonucleotides, Antisense; Radiation Tolerance; Transfection; Tumor Cells, Cultured; Ultraviolet Rays

2002
[Effects of 2,450 MHz microwave on DNA damage induced by three chemical mutagens in vitro].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2003, Volume: 21, Issue:4

    Topics: Bleomycin; Comet Assay; DNA; DNA Damage; Humans; Lymphocytes; Methyl Methanesulfonate; Microwaves; Mitomycin; Mutagens; Time Factors

2003
Characterization of the hamster FancG/Xrcc9 gene and mutations in CHO UV40 and NM3.
    Mutagenesis, 2004, Volume: 19, Issue:3

    Topics: Alkylating Agents; Amino Acid Sequence; Animals; CHO Cells; Cricetinae; DNA-Binding Proteins; Fanconi Anemia; Fanconi Anemia Complementation Group G Protein; Methyl Methanesulfonate; Mitomycin; Molecular Sequence Data; Mutagens; Mutation

2004
Relative cytotoxicity values at the lowest effective concentration for 12 positive chemicals in the in vitro micronucleus test utilizing Chinese hamster ovary cells.
    Mutation research, 2004, Jul-11, Volume: 561, Issue:1-2

    Topics: Animals; Benz(a)Anthracenes; Bleomycin; Cell Count; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Cyclophosphamide; Dactinomycin; Dose-Response Relationship, Drug; Etoposide; Female; Griseofulvin; Hazardous Substances; Hydrogen Peroxide; Hydroxyurea; Methyl Methanesulfonate; Mitomycin; Phenol; Vinblastine

2004
[TK locus mutation assay: comparison of L5178Y and TK6 cell lines].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2004, Volume: 35, Issue:5

    Topics: Animals; Cell Line, Tumor; Ethyl Methanesulfonate; Humans; Leukemia L5178; Lymphoma; Methyl Methanesulfonate; Mice; Mitomycin; Mutagenicity Tests; Mutation; Thymidine Kinase

2004
Extensive chromosomal instability in Rad51d-deficient mouse cells.
    Cancer research, 2005, Mar-15, Volume: 65, Issue:6

    Topics: Animals; Cell Culture Techniques; Centrosome; Chromosomal Instability; Cisplatin; DNA Damage; DNA-Binding Proteins; Embryo, Mammalian; Fibroblasts; Methyl Methanesulfonate; Mice; Mice, Inbred C57BL; Mitomycin; Sister Chromatid Exchange; Tumor Suppressor Protein p53

2005
Studying the synergistic damage effects induced by 1.8 GHz radiofrequency field radiation (RFR) with four chemical mutagens on human lymphocyte DNA using comet assay in vitro.
    Mutation research, 2005, Oct-15, Volume: 578, Issue:1-2

    Topics: 4-Nitroquinoline-1-oxide; Adult; Bleomycin; Comet Assay; DNA; Drug Synergism; Humans; Lymphocytes; Male; Methyl Methanesulfonate; Microwaves; Mitomycin; Mutagens

2005
Antioxidative and antigenotoxic effects of Japanese horse chestnut (Aesculus turbinata) seeds.
    The Journal of veterinary medical science, 2005, Volume: 67, Issue:7

    Topics: Aesculus; Aflatoxin B1; Anthracenes; Antimutagenic Agents; Antioxidants; Dose-Response Relationship, Drug; Furylfuramide; Hydrogen Peroxide; Linoleic Acid; Methyl Methanesulfonate; Methylnitrosourea; Mitomycin; Phenols; Plant Extracts; Seeds

2005
[Influence of 1.8 GHz microwave on DNA damage induced by 4 chemical mutagens].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2005, Volume: 23, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; Adult; Bleomycin; Cells, Cultured; Comet Assay; DNA; DNA Damage; Humans; Lymphocytes; Male; Methyl Methanesulfonate; Microwaves; Mitomycin; Mutagens

2005
Cellular characterization of cells from the Fanconi anemia complementation group, FA-D1/BRCA2.
    Mutation research, 2006, Oct-10, Volume: 601, Issue:1-2

    Topics: Bleomycin; BRCA2 Protein; Cell Survival; Cells, Cultured; Chromosome Aberrations; DNA Damage; DNA Repair; Fanconi Anemia; Fanconi Anemia Complementation Group Proteins; Fibroblasts; Humans; Methyl Methanesulfonate; Mitomycin; Sister Chromatid Exchange

2006
Four human FANCG polymorphic variants show normal biological function in hamster CHO cells.
    Mutation research, 2006, Dec-01, Volume: 602, Issue:1-2

    Topics: Animals; Cells, Cultured; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Fanconi Anemia Complementation Group D2 Protein; Fanconi Anemia Complementation Group G Protein; Gene Frequency; Genetic Complementation Test; Humans; Methyl Methanesulfonate; Mitomycin; Polymorphism, Genetic; Ubiquitin

2006
Colostrinin decreases spontaneous and induced mutation frequencies at the hprt locus in Chinese hamster V79 cells.
    Journal of experimental therapeutics & oncology, 2006, Volume: 5, Issue:4

    Topics: Animals; Antimutagenic Agents; Cell Cycle; Cricetinae; DNA Mutational Analysis; Dose-Response Relationship, Drug; Hypoxanthine Phosphoribosyltransferase; Intercellular Signaling Peptides and Proteins; Methyl Methanesulfonate; Mitomycin; Mutagens; Mutation; Oxidative Stress; Peptides; Reactive Oxygen Species

2006
[The tk gene mutation analysis in WTK1 cell line by multiplex PCR].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2006, Volume: 37, Issue:5

    Topics: Cells, Cultured; Humans; Lymphocytes; Methyl Methanesulfonate; Mitomycin; Mutagenicity Tests; Mutation; Polymerase Chain Reaction; Sodium Azide; Thymidine Kinase

2006
Protective effect of DCTN (trans-dehydrocrotonin) against induction of micronuclei and apoptosis by different mutagenic agents in vitro.
    Mutation research, 2007, Apr-20, Volume: 629, Issue:1

    Topics: Animals; Antimutagenic Agents; Apoptosis; CHO Cells; Cricetinae; Cricetulus; Croton; Diterpenes, Clerodane; Dose-Response Relationship, Drug; Doxorubicin; In Vitro Techniques; Methyl Methanesulfonate; Micronucleus Tests; Mitomycin; Molecular Structure; Mutagens; Plants, Medicinal

2007
Analysis of DNA repair and recombination responses in mouse cells depleted for Brca2 by SiRNA.
    DNA repair, 2007, Jun-01, Volume: 6, Issue:6

    Topics: Animals; Apoptosis Regulatory Proteins; BRCA2 Protein; DNA Damage; DNA Repair; Gene Targeting; Genetic Techniques; Genome; Hybridomas; Methyl Methanesulfonate; Mice; Mitomycin; Mutation; Radiation, Ionizing; Recombination, Genetic; RNA, Small Interfering

2007
Bacillus subtilis RecG branch migration translocase is required for DNA repair and chromosomal segregation.
    Molecular microbiology, 2007, Volume: 65, Issue:4

    Topics: Bacillus subtilis; Bacterial Proteins; Chromosome Segregation; Chromosomes, Bacterial; DNA Breaks, Double-Stranded; DNA Repair; Enzyme Activation; Gene Deletion; Methyl Methanesulfonate; Microbial Viability; Mitomycin; Mutation; Recombination, Genetic; Suppression, Genetic

2007
Constitutive SOS expression and damage-inducible AddAB-mediated recombinational repair systems for Coxiella burnetii as potential adaptations for survival within macrophages.
    Molecular microbiology, 2008, Volume: 69, Issue:6

    Topics: Adaptation, Physiological; Amino Acid Sequence; Animals; Bacterial Proteins; Cell Line; Coxiella burnetii; DNA Damage; Escherichia coli; Exodeoxyribonucleases; Gene Expression Profiling; Macrophages; Methyl Methanesulfonate; Mice; Microbial Viability; Mitomycin; Molecular Sequence Data; Mutagens; Rec A Recombinases; Recombination, Genetic; Sequence Alignment; SOS Response, Genetics; Ultraviolet Rays

2008
Intralaboratory and interlaboratory evaluation of the EpiDerm 3D human reconstructed skin micronucleus (RSMN) assay.
    Mutation research, 2009, Mar-17, Volume: 673, Issue:2

    Topics: Animal Testing Alternatives; Epidermis; Glycols; Humans; Laboratories; Methyl Methanesulfonate; Micronucleus Tests; Mitomycin; Mutagens; Nitrophenols; Reproducibility of Results; Skin; Skin Irritancy Tests; Tissue Engineering; Trichloroethylene; Vinblastine

2009
Characterization in vitro and in vivo of the DNA helicase encoded by Deinococcus radiodurans locus DR1572.
    DNA repair, 2009, May-01, Volume: 8, Issue:5

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Antineoplastic Agents, Alkylating; Bacterial Proteins; Blotting, Southern; Cloning, Molecular; Deinococcus; DNA Damage; DNA Helicases; DNA Repair; Gamma Rays; Hydrogen Peroxide; Hydrolysis; In Vitro Techniques; Methyl Methanesulfonate; Mitomycin; Molecular Sequence Data; Mutation; Nucleic Acid Synthesis Inhibitors; Oxidants; Polymerase Chain Reaction; Sequence Homology, Amino Acid; Ultraviolet Rays

2009
The role of novel genes rrp1(+) and rrp2(+) in the repair of DNA damage in Schizosaccharomyces pombe.
    DNA repair, 2009, May-01, Volume: 8, Issue:5

    Topics: Amino Acid Sequence; Antineoplastic Agents, Alkylating; Cloning, Molecular; DNA Damage; DNA Repair; DNA-Binding Proteins; DNA, Fungal; Gamma Rays; Hydrogen Peroxide; Methyl Methanesulfonate; Mitomycin; Molecular Sequence Data; Mutation; Nucleic Acid Synthesis Inhibitors; Oxidants; Saccharomyces cerevisiae Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Sequence Homology, Amino Acid; Ultraviolet Rays

2009
Replication protein A (RPA1a) is required for meiotic and somatic DNA repair but is dispensable for DNA replication and homologous recombination in rice.
    Plant physiology, 2009, Volume: 151, Issue:4

    Topics: Chromosomes, Plant; DNA Fragmentation; DNA Repair; DNA Replication; DNA, Bacterial; Genes, Plant; Genetic Complementation Test; Germ Cells, Plant; Meiosis; Methyl Methanesulfonate; Mitomycin; Mitosis; Mutagens; Mutation; Oryza; Phenotype; Plant Proteins; Plants, Genetically Modified; Pollen; Recombination, Genetic; Replication Protein A; RNA Interference; Ultraviolet Rays

2009
A flow cytometry based in vitro micronucleus assay in TK6 cells--validation using early stage pharmaceutical development compounds.
    Environmental and molecular mutagenesis, 2011, Volume: 52, Issue:5

    Topics: Benzo(a)pyrene; Cell Line, Tumor; Cell Survival; Cyclophosphamide; Flow Cytometry; Humans; Methyl Methanesulfonate; Micronucleus Tests; Mitomycin; Sucrose; Vinblastine

2011
Genetic analysis of DNA repair in the hyperthermophilic archaeon, Thermococcus kodakaraensis.
    Genes & genetic systems, 2010, Volume: 85, Issue:4

    Topics: Archaeal Proteins; DNA Helicases; DNA Mutational Analysis; DNA Repair; DNA, Archaeal; Endonucleases; Gamma Rays; Gene Deletion; Gene Knockout Techniques; Methyl Methanesulfonate; Mitomycin; Mutation; Thermococcaceae; Ultraviolet Rays

2010
An evolutionarily acquired genotoxic response discriminates MyoD from Myf5, and differentially regulates hypaxial and epaxial myogenesis.
    EMBO reports, 2011, Volume: 12, Issue:2

    Topics: Animals; Ataxia Telangiectasia Mutated Proteins; Biological Evolution; Cell Cycle Proteins; Cell Differentiation; Cells, Cultured; Coculture Techniques; Cross-Linking Reagents; DNA Damage; DNA-Binding Proteins; Etoposide; Female; Gene Knockdown Techniques; Methyl Methanesulfonate; Mice; Mitomycin; Muscle Development; Mutagens; MyoD Protein; Myogenic Regulatory Factor 5; Phosphorylation; Pregnancy; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-abl; RNA Interference; Somites; Tumor Suppressor Proteins

2011
Recruitment of HRDC domain of WRN and BLM to the sites of DNA damage induced by mitomycin C and methyl methanesulfonate.
    Cell biology international, 2012, Oct-01, Volume: 36, Issue:10

    Topics: Antineoplastic Agents; DNA Damage; DNA Helicases; Exodeoxyribonucleases; HeLa Cells; Humans; Methyl Methanesulfonate; Mitomycin; Protein Structure, Tertiary; RecQ Helicases; Ribonuclease III; Transfection; Werner Syndrome Helicase

2012
Insensitivity of the in vitro cytokinesis-block micronucleus assay with human lymphocytes for the detection of DNA damage present at the start of the cell culture.
    Mutagenesis, 2012, Volume: 27, Issue:6

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Cell Culture Techniques; Cell Nucleus; Cells, Cultured; Comet Assay; Cytokinesis; DNA Damage; Epoxy Compounds; Ethyl Methanesulfonate; Ethylnitrosourea; Female; Humans; Lymphocytes; Male; Methyl Methanesulfonate; Micronucleus Tests; Mitomycin; Mutagenicity Tests; Mutagens

2012
hPNAS-4 inhibits proliferation through S phase arrest and apoptosis: underlying action mechanism in ovarian cancer cells.
    Apoptosis : an international journal on programmed cell death, 2013, Volume: 18, Issue:4

    Topics: Apoptosis; Apoptosis Inducing Factor; Apoptosis Regulatory Proteins; Carbon-Nitrogen Lyases; Caspase 3; Caspase 8; Caspase 9; cdc25 Phosphatases; Cell Line, Tumor; Cell Proliferation; Cisplatin; Cyclin A; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Cytochromes c; DNA Damage; Enzyme Activation; Female; Humans; Intracellular Signaling Peptides and Proteins; Methyl Methanesulfonate; Mitochondrial Proteins; Mitomycin; Ovarian Neoplasms; S Phase Cell Cycle Checkpoints; Up-Regulation

2013
A combination of in vitro comet assay and micronucleus test using human lymphoblastoid TK6 cells.
    Mutagenesis, 2013, Volume: 28, Issue:5

    Topics: Cell Survival; Cells, Cultured; Comet Assay; Cross-Linking Reagents; Cytotoxins; Ethyl Methanesulfonate; Gamma Rays; Humans; Hydrogen Peroxide; Methyl Methanesulfonate; Micronucleus Tests; Mitomycin; Mutagenicity Tests; Mutagens; Octoxynol; Sensitivity and Specificity

2013
Automation and validation of micronucleus detection in the 3D EpiDerm™ human reconstructed skin assay and correlation with 2D dose responses.
    Mutagenesis, 2014, Volume: 29, Issue:3

    Topics: Automation; Carbamates; Cell Line; DNA Glycosylases; Dose-Response Relationship, Drug; Gene Expression; Humans; Hydrogen Peroxide; Keratinocytes; Methyl Methanesulfonate; Micronucleus Tests; Mitomycin; Reproducibility of Results; RNA, Messenger; Skin; Tissue Culture Techniques

2014
Genotoxins induce binucleation in L5178Y and TK6 cells.
    Mutation research. Genetic toxicology and environmental mutagenesis, 2014, Volume: 770

    Topics: Animals; Cell Line; Colchicine; Cytarabine; Cytokinesis; DNA Damage; Humans; Methyl Methanesulfonate; Methylnitrosourea; Mice; Micronucleus Tests; Mitomycin; Mutagens

2014
Catalytic and non-catalytic roles of DNA polymerase κ in the protection of human cells against genotoxic stresses.
    Environmental and molecular mutagenesis, 2015, Volume: 56, Issue:8

    Topics: Benzo(a)pyrene; Cell Line; Cell Survival; DNA Damage; DNA-Directed DNA Polymerase; Genetic Complementation Test; Humans; Hydrogen Peroxide; Methyl Methanesulfonate; Mitomycin; Mutagens; Ultraviolet Rays; Vitamin K 3

2015
Antigenotoxic effects of resveratrol: assessment of in vitro and in vivo response.
    Mutagenesis, 2016, Volume: 31, Issue:1

    Topics: 4-Nitroquinoline-1-oxide; Animals; Antimutagenic Agents; Bone Marrow Cells; Chromosome Aberrations; Chromosomes; DNA Damage; Epoxy Compounds; HL-60 Cells; Humans; Male; Methyl Methanesulfonate; Mice; Micronucleus Tests; Mitomycin; Procarbazine; Quinolones; Resveratrol; Stilbenes

2016
Comparative study of human neuronal and glial cell sensitivity for in vitro neurogenotoxicity testing.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2017, Volume: 102

    Topics: Bleomycin; Cell Line; Comet Assay; Dactinomycin; DNA Damage; Griseofulvin; Humans; Methyl Methanesulfonate; Micronucleus Tests; Mitomycin; Mutagenicity Tests; Mutagens; Neuroglia; Neurons; Neurotoxicity Syndromes

2017
Single molecule tracking reveals functions for RarA at replication forks but also independently from replication during DNA repair in Bacillus subtilis.
    Scientific reports, 2019, 02-13, Volume: 9, Issue:1

    Topics: Adenosine Triphosphatases; Bacillus subtilis; DNA Helicases; DNA Repair; DNA Replication; DNA, Bacterial; Gene Expression Regulation, Bacterial; Hydrogen Peroxide; Methyl Methanesulfonate; Mitomycin; Rec A Recombinases; Single Molecule Imaging

2019
Development of an integrated assay in human TK6 cells to permit comprehensive genotoxicity analysis in vitro.
    Mutation research. Genetic toxicology and environmental mutagenesis, 2020, Volume: 849

    Topics: 4-Nitroquinoline-1-oxide; Benzo(a)pyrene; Cell Line, Tumor; Cyclophosphamide; Diclofenac; DNA; DNA Damage; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation; Humans; Lymphocytes; Methyl Methanesulfonate; Micronuclei, Chromosome-Defective; Mitomycin; Mutagenesis; Mutagenicity Tests; Mutation; Thymidine Kinase; Vinblastine

2020