Page last updated: 2024-08-16

mitomycin and mercaptopurine

mitomycin has been researched along with mercaptopurine in 30 studies

Research

Studies (30)

Timeframe	Studies, this research(%)	All Research%
pre-1990	14 (46.67)	18.7374
1990's	11 (36.67)	18.2507
2000's	0 (0.00)	29.6817
2010's	5 (16.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Dorr, RT; Iyengar, BS; Remers, WA	1
Hansch, C; Khwaja, TA; Selassie, CD	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Benfenati, E; Raska, I; Toropov, AA; Toropova, AP	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Hayashi, M; Ishidate, M; Norppa, H; Sofuni, T	1
Ambaye, RY; Indap, MA	1
Hayashi, M; Morita, T; Sofuni, T	1
Sato, S; Sutou, S	1
Arakawa, M; Ekimoto, H; Nagahata, T; Takahashi, K; Uchida, T	1
Hoshino, A; Ito, Y; Machida, S	1
Okuma, K; Ota, K	1
Fukawa, H; Ikezaki, K; Kishiye, T; Komiyama, S; Kuwano, M; Mamizuka, K; Otake, N; Seto, H; Sugita, M; Yamaguchi, T	1
Hayashi, M; Ishidate, M; Sofuni, T	1
Hirano, S; Iguchi, H; Izumi, H; Matsushita, Y; Takeuchi, T; Tone, H	1
Bentel, GC; Brown, M; Burger, P; Byrne, T; Cairncross, JG; Dropcho, E; Fischer, B; Friedman, A; Gaspar, L; Hait, W; Halperin, EC; Herndon, J; Imperato, J; Khandekar, J; Macdonald, DR; Morowitz, R; Paleologos, N; Piepmeier, J; Rosenfeld, S; Salter, M; Schold, SC; Vick, N	1
Anguiano-Orozco, G; Morales-Ramírez, P; Rodríguez-Reyes, R; Vallarino-Kelly, T	1
Mine, Y; Miyamae, Y; Ohara, K; Sasaki, YF; Zaizen, K	1
KUNI, A; ONO, S; YAMADA, H	1
HATA, T; HOSSENLOPP, C; TAKITA, H	1
GOLDENBERG, DM	1
ANDERSON, EP; BROCKMAN, RW	1
ADACHI, A; MIYAMOTO, K; NAKAMURA, T; SAKURAI, M; SHIRAKAWA, S; UCHINO, H; WAKISAKA, G	1
KOISO, K	1
SAKURAI, Y	1
SUBAK-SHARPE, H	1
BOSTICK, WL; DAWSON, PJ; FIELDSTEEL, AH	1
HANO, K; NISHINO, Y	1

Reviews

3 review(s) available for mitomycin and mercaptopurine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Pulmonary toxicity of antineoplastic agents--with special reference to current findings on pulmonary toxicity of bleomycin]. Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:9 Topics: Animals; Antineoplastic Agents; Bleomycin; Busulfan; Cyclophosphamide; Humans; Lung; Mercaptopurine; Methotrexate; Mitomycin; Mitomycins; Nitrosourea Compounds; Postoperative Complications; Procarbazine	1982
BIOCHEMISTRY OF CANCER (METABOLIC ASPECTS). Annual review of biochemistry, 1963, Volume: 32 Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Azaguanine; Azaserine; Carcinoma, Ehrlich Tumor; DNA; DNA, Neoplasm; Floxuridine; Fluorouracil; Folic Acid; Glutamine; Leukemia L1210; Mercaptopurine; Methotrexate; Mitomycin; Neoplasms; Neoplasms, Experimental; Pharmacology; Purines; Puromycin; Pyrimidines; Research; RNA; RNA, Neoplasm; Thioguanine; Thiouracil	1963

Trials

1 trial(s) available for mitomycin and mercaptopurine

Article	Year
A phase III randomized prospective trial of external beam radiotherapy, mitomycin C, carmustine, and 6-mercaptopurine for the treatment of adults with anaplastic glioma of the brain. CNS Cancer Consortium. International journal of radiation oncology, biology, physics, 1996, Mar-01, Volume: 34, Issue:4 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined Modality Therapy; Female; Glioblastoma; Humans; Karnofsky Performance Status; Male; Mercaptopurine; Middle Aged; Mitomycin; Prospective Studies; Quality Assurance, Health Care; Survival Rate	1996

Article

Year

A phase III randomized prospective trial of external beam radiotherapy, mitomycin C, carmustine, and 6-mercaptopurine for the treatment of adults with anaplastic glioma of the brain. CNS Cancer Consortium.

International journal of radiation oncology, biology, physics, 1996, Mar-01, Volume: 34, Issue:4

Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined Modality Therapy; Female; Glioblastoma; Humans; Karnofsky Performance Status; Male; Mercaptopurine; Middle Aged; Mitomycin; Prospective Studies; Quality Assurance, Health Care; Survival Rate

1996

Other Studies

26 other study(ies) available for mitomycin and mercaptopurine

Article	Year
Additional nucleotide derivatives of mitosenes. Synthesis and activity against parental and multidrug resistant L1210 leukemia. Journal of medicinal chemistry, 1991, Volume: 34, Issue:7 Topics: Animals; Antineoplastic Agents; Cell Line; Chemical Phenomena; Chemistry; Leukemia L1210; Mice; Mitomycin; Mitomycins; Nucleotides	1991
Structure-activity relationships of antineoplastic agents in multidrug resistance. Journal of medicinal chemistry, 1990, Volume: 33, Issue:7 Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured	1990
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations. European journal of medicinal chemistry, 2010, Volume: 45, Issue:4 Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Flow cytometric micronucleus test with mouse peripheral erythrocytes. Mutagenesis, 1992, Volume: 7, Issue:4 Topics: Algorithms; Animals; Benzene; Benzo(a)pyrene; Chromates; Erythrocytes; Ethylnitrosourea; Flow Cytometry; Hydrocarbons, Halogenated; Male; Mercaptopurine; Mice; Mice, Inbred Strains; Micronucleus Tests; Mitomycin; Mutagens; Potassium Compounds; Trihalomethanes	1992
Influence of N-(o-methoxyphenyl)-maleimide on 5-fluorouracil cytotoxicity in Ehrlich (ascites) carcinoma. Cancer letters, 1991, Volume: 57, Issue:1 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Ehrlich Tumor; Cyclophosphamide; Cytarabine; Fluorouracil; Maleimides; Mechlorethamine; Mercaptopurine; Mice; Mitomycin; Mitomycins; Vinblastine	1991
Simulation study of the effects of multiple treatments in the mouse bone marrow micronucleus test. Mutation research, 1991, Volume: 252, Issue:3 Topics: Animals; Bone Marrow; Bone Marrow Cells; Cytarabine; Erythrocytes; Kinetics; Male; Mercaptopurine; Methotrexate; Mice; Mice, Inbred Strains; Micronucleus Tests; Mitomycin; Mitomycins; Models, Biological; Mutagens	1991
Maternal effect on micronucleus induction in MS/Ae mice. Environmental and molecular mutagenesis, 1990, Volume: 15, Issue:3 Topics: Animals; Animals, Newborn; Cell Differentiation; Colchicine; Extrachromosomal Inheritance; Female; Litter Size; Male; Mercaptopurine; Mice; Mice, Inbred Strains; Micronucleus Tests; Mitomycin; Mitomycins; Pregnancy	1990
[Experimental combination chemotherapy of YNK01, a novel analog of cytarabine, with other antitumor agents]. Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:7 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleotides; Cisplatin; Cytidine Monophosphate; Cytosine Nucleotides; Daunorubicin; Doxorubicin; Drug Synergism; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Mercaptopurine; Mice; Mice, Inbred DBA; Mitomycin; Mitomycins; Vincristine	1990
[Effects of combination chemotherapy of MCNU with various anti-cancer agents]. Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:2 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Female; Fluorouracil; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Mercaptopurine; Methotrexate; Mice; Mice, Inbred DBA; Mitomycin; Mitomycins; Nitrosourea Compounds; Thioguanine	1985
Potentiation of mitomycin C, 6-mercaptopurine, bleomycin, cis-diamminedichloroplatinum and 5-fluorouracil by mycotrienins and mycotrienols. Gan, 1983, Volume: 74, Issue:5 Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Bleomycin; Cell Division; Cell Line; Cell Survival; Cisplatin; Cricetinae; Cricetulus; Drug Synergism; Fluorouracil; Hydroquinones; Macrolides; Mercaptopurine; Mitomycin; Mitomycins; Quinones	1983
Kinetics of micronucleus formation in relation to chromosomal aberrations in mouse bone marrow. Mutation research, 1984, Volume: 127, Issue:2 Topics: Animals; Bone Marrow; Cell Nucleus; Chromosome Aberrations; Cytarabine; Erythrocytes, Abnormal; Male; Mercaptopurine; Mice; Mitomycin; Mitomycins; Mitosis; Mutagenicity Tests; Time Factors	1984
Experimental combination chemotherapy of pirarubicin with various antitumor drugs against P388 murine leukemia. Cancer biochemistry biophysics, 1994, Volume: 14, Issue:2 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Screening Assays, Antitumor; Fluorouracil; Leukemia P388; Male; Mercaptopurine; Methotrexate; Mice; Mice, Inbred BALB C; Mitomycin; Peplomycin; Vindesine	1994
Pharmacokinetic parameters of genotoxic activity inferred from the comparison of the kinetics of MN-PCE induced by chemical agents and ionizing radiation. Mutation research, 1997, Jul-14, Volume: 391, Issue:3 Topics: Animals; Cyclophosphamide; Cytarabine; Dose-Response Relationship, Radiation; Erythrocytes; Male; Mercaptopurine; Mice; Mice, Inbred BALB C; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mitomycin; Mutagens; Nucleic Acid Synthesis Inhibitors	1997
Detection of DNA lesions induced by chemical mutagens by the single cell gel electrophoresis (Comet) assay. 1. Relationship between the onset of DNA damage and the characteristics of mutagens. Mutation research, 1997, Sep-18, Volume: 393, Issue:1-2 Topics: Animals; Bleomycin; Cross-Linking Reagents; DNA Damage; Electrophoresis; Leukemia L5178; Mercaptopurine; Methyl Methanesulfonate; Methylnitrosourea; Mice; Mitomycin; Mutagenicity Tests; Mutagens; Nucleic Acid Synthesis Inhibitors; Time Factors; Tumor Cells, Cultured; Ultraviolet Rays; X-Rays	1997
[On the medical therapy of malignant lymphoma]. Naika. Internal medicine, 1962, Volume: 10 Topics: Antineoplastic Agents; Azaguanine; Cortisone; Cyclophosphamide; Humans; Lymphoma; Mercaptopurine; Mitomycin; Mitomycins; Nitrogen Mustard Compounds; Prednisolone; Thiotepa; Triethylenemelamine	1962
Comparative studies of antitumor activities of mitomycin C and 6-mercaptopurine. The Journal of antibiotics, 1961, Volume: 14 Topics: Animals; Antineoplastic Agents; Carcinoma; Mercaptopurine; Mitomycin; Sarcoma, Experimental	1961
DRUGS OF CURRENT USE FOR THE TREATMENT OF CANCER AND ALLIED DISEASES. Diseases of the chest, 1963, Volume: 51 Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antineoplastic Agents; Aziridines; Busulfan; Colchicine; Dactinomycin; Diethylstilbestrol; Estrogens; Fluorouracil; Gonadal Steroid Hormones; Mercaptopurine; Methotrexate; Mitomycin; Mitomycins; Neoplasms; Podophyllum; Progestins; Quinones; Thiotepa; Triethylenemelamine; Urethane; Vinblastine	1963
PRESENT STATUS OF LEUKEMIA IN JAPAN WITH SPECIAL REFERENCE TO EPIDEMIOLOGY AND STUDIES ON THE EFFECT OF CHEMOTHERAPY. Acta haematologica, 1964, Volume: 31 Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Asian People; Busulfan; DNA; DNA, Neoplasm; Epidemiology; Formates; Geriatrics; Humans; Infant; Japan; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Mitomycin; Neoplasms; Prednisolone; RNA; RNA, Neoplasm	1964
[STUDIES ON THE NUCLEIC ACID METABOLISM OF HUMAN LEUKEMIC LEUKOCYTES IN VITRO]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1964, May-10, Volume: 53 Topics: Adenine Nucleotides; Bone Marrow; Cyclophosphamide; DNA; Formates; Guanine Nucleotides; Humans; In Vitro Techniques; Leukemia; Leukemia, Myeloid; Leukocytes; Mercaptopurine; Metabolism; Mitomycin; Mitomycins; Pharmacology; Prednisolone; Rabbits; Research; RNA; Thymine	1964
IN VITRO CULTURE OF YOSHIDA SARCOMA CELLS: METHODS FOR DETERMINING ACQUIRED RESISTANCE TO DRUGS. National Cancer Institute monograph, 1964, Volume: 16 Topics: Animals; Antineoplastic Agents; Azaguanine; Culture Media; Cyclophosphamide; Dactinomycin; Drug Tolerance; Fluorouracil; Glucosamine; Histocytochemistry; In Vitro Techniques; Mechlorethamine; Mercaptopurine; Mitomycin; Mitomycins; Neoplasm Transplantation; Neoplasms; Nitrogen Mustard Compounds; Pharmacology; Rats; Research; Sarcoma; Sarcoma, Experimental; Sarcoma, Yoshida; Thiotepa; Tissue Culture Techniques	1964
BIOCHEMICALLY MARKED VARIANTS OF THE SYRIAN HAMSTER FIBROBLAST CELL LINE BHK21 AND ITS DERIVATIVES. Experimental cell research, 1965, Volume: 38 Topics: 2-Aminopurine; Amphotericin B; Animals; Antineoplastic Agents; Azaguanine; Bromodeoxyuridine; Carbon Isotopes; Cell Division; Cell Line; Cricetinae; Dactinomycin; Fibroblasts; Floxuridine; Fluorouracil; Hexoses; Hypoxanthines; Mercaptopurine; Mesocricetus; Metabolism; Mitomycin; Mitomycins; Mutation; Nucleosides; Pharmacology; Puromycin; Research; Thioguanine; Tissue Culture Techniques; Tritium; Vinblastine	1965
EFFECT OF DRUGS ON CELL AND VIRUS GROWTH IN FRIEND LEUKEMIA AND A TUMOR VARIANT. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 119 Topics: Animals; Estradiol; Friends; Leukemia; Leukemia Virus, Murine; Leukemia, Experimental; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mercaptopurine; Methylcellulose; Mice; Mitomycin; Mitomycins; Neoplasm Transplantation; Neoplasms; Pharmacology; Research; Sarcoma; Triethylenemelamine; Urethane	1965
PHARMACOLOGICAL STUDIES ON THE METABOLISM OF MUCOPOLYSACCHARIDES IN TUMOR CELLS. Gan, 1965, Volume: 56 Topics: Animals; Carbohydrate Metabolism; Carcinoma, Ehrlich Tumor; Glucuronidase; Glycosaminoglycans; Hexosamines; Hyaluronoglucosaminidase; Injections, Intraperitoneal; Mercaptopurine; Mice; Mitomycin; Mitomycins; Pharmacology; Research; Thiotepa	1965