Page last updated: 2024-08-16

mitomycin and melphalan

mitomycin has been researched along with melphalan in 70 studies

Research

Studies (70)

Timeframe	Studies, this research(%)	All Research%
pre-1990	21 (30.00)	18.7374
1990's	22 (31.43)	18.2507
2000's	14 (20.00)	29.6817
2010's	12 (17.14)	24.3611
2020's	1 (1.43)	2.80

Authors

Authors	Studies
Hansch, C; Khwaja, TA; Selassie, CD	1
Barrows, LR; Ireland, CM; Kokoshka, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Benfenati, E; Raska, I; Toropov, AA; Toropova, AP	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Averette, HE; Donato, D; Nguyen, HN; Penalver, M; Perras, J; Sevin, BU	1
Cold, S; Pfeiffer, P; Rose, C	1
D'Alessandro, N; Gebbia, N; Gebbia, V; Palmeri, S; Rausa, L; Russo, A	1
Bernard, GS; Hobbs, ML; Mellard, DN; Meyn, RE; Murray, D; vanAnkeren, SC	1
Gebhart, E; Herrera, LA; Ostrosky-Wegman, P; Tittelbach, H	1
Fujimaru, J; Ogura, M; Takeda, Y; Tomiyoshi, Y; Wada, Y; Yoshida, S	1
Basu, A; Lazo, JS	1
Caldecott, K; Jeggo, P	1
Ishige, H; Iwasawa, H; Sekiya, S; Takamizawa, H; Tanaka, N; Tokita, H	1
Ezaki, T; Fujioka, T; Miyagi, N; Nakatani, K; Sakamoto, K; Shiratori, T; Sugisaki, T; Watanabe, A	1
Aigner, KR; Link, KH; Müller, H; Voigt, H; Walther, H	1
Portnoĭ, AS	1
Imai, S; Kan, N; Nio, Y; Ohgaki, K; Tobe, T; Tsuchitani, T	1
Erlichman, C; Vidgen, D; Wu, A	1
Hickson, ID; Robson, CN	1
Kimura, Y; Takeda, Y; Wada, Y; Yoshida, S	1
Rubin, JS; Whitmore, GF	1
Dozi-Vassiliades, J; Mourelatos, D	1
Alberts, DS; Mason, N; Salmon, SE; Young, L	1
Ben-Efraim, S; Bocian, RC; Dray, S; Mokyr, MB	2
Hashimura, T; Hikasa, Y; Honda, K; Kern, DH; Mizuno, Y; Niwa, O; Satomura, K; Sugahara, T; Tanigawa, N; Yoshida, O	1
Coombes, RC; Ford, HT; Gazet, JC; Perez, DJ; Powles, TJ	1
Cook, RL; Houghton, JA; Houghton, PJ; Lutz, PJ	1
Alaoui-Jamali, M; Aubin, R; Batist, G; Bramson, J; Christodoulopoulos, G; McQuillan, A; Panasci, LC	1
Gorelik, L; Mokyr, MB; Prokhorova, A	1
Folman, RS	1
Hortobagyi, GN	1
Powles, TJ; Smith, IE	1
Abu-Abid, S; Chaitchik, S; Chen, Z; Gutman, M; Inbar, M; Klausner, JM; Lev, D; Oron, D; Sorkine, P	1
Hanada, R; Hongo, T; Horikoshi, Y; Sakurai, M; Yajima, S	1
Hisai, H; Ikeda, S; Katahira, T; Kondo, H; Saito, T; Takahashi, Y; Takayama, T	1
Ben-Ari, GY	1
Marinelli, A; Vahrmeijer, AL; van de Velde, CJ	1
de Boeck, G; de Bruijn, EA; Eggermont, AM; ten Hagen, TL; van der Sijp, JR; van Ijken, MG	1
Aalders, M; Beijnen, JH; Essers, M; Kuin, A; Lamfers, M; Smets, LA; van Zuidam, DJ	1
Aquilina, G; Bignami, M; Colussi, C; Crescenzi, M; Fiumicino, S; Leonetti, C; Martinelli, S	1
Danenberg, PV; Kornmann, M; Leder, GH; Link, KH; Pillasch, J	1
Bluestone, JA; Donepudi, M; Mokyr, MB; Sojka, DK	1
Ben-Ari, G; Koller, M; Papa, M; Sareli, M; Scott, D; Zippel, D	1
Eggermont, AM; Erdmann, W; Hofland, J; Tenbrinck, R; van Eijck, CH; van IJken, MG	1
Amicucci, G; Deraco, M; Di Filippo, F; Fiorentini, G; Guadagni, S; Miotto, D; Patuzzo, R; Pilati, PL; Rossi, CR; Santinami, M; Valenti, M	1
BERGSAGEL, DE	1
SAMPEY, JR	1
KNOCK, FE	1
HANDLER, AH; SARRIS, TG; WILLS, C	1
GARATTINI, S; PALMA, V; REYERS-DEGLIINNOCENTI, I	1
Asada, Y; Fujisawa, K; Iida, Y; Kasahara, Y; Mitsui, T; Miura, S; Munemoto, Y; Ohata, K; Saito, H	1
Cejka, P; Jiricny, J; Papouli, E	1
de Bruijn, EA; Eggermont, AM; Guetens, G; Jeekel, J; ten Hagen, TL; van Eijck, CH; van Etten, B; van IJken, MG	1
de Boeck, G; de Bruijn, EA; Eggermont, AM; ten Hagen, TL; van Eijck, CH; van IJken, MG	1
de Bruijn, EA; Eggermont, AM; Guetens, G; Ten Hagen, TL; van Etten, B; van Ijken, MG; Wiggers, T	1
Brody, JR; Cunningham, SC; DeMarzo, AM; Dezentje, DA; Gallmeier, E; Hruban, RH; Isacoff, WH; Kern, SE; Offerhaus, GJ; Swartz, MJ; van der Heijden, MS	1
Arakawa, H; Araki, K; Bishop, DK; Buerstedde, JM; Fukushima, T; Hashimoto, N; Hirano, S; Hochegger, H; Ishiai, M; Kawamoto, T; Kikuchi, K; Nojima, K; Ohzeki, M; Orelli, BJ; Saberi, A; Sonoda, E; Takahashi, JA; Takata, M; Takeda, S; Yamamoto, K; Yamazoe, M; Yoshimura, M	1
Glimelius, B; Graf, W; Grundmark, B; Larsson, R; Mahteme, H; Nygren, P; Påhlman, L; Tholander, B; von Heideman, A	1
Desai, AP; Khan, MA; Lanitis, S; Rosin, RD	1
Gushchin, V; Jimenez, WA; Macdonald, R; Nieroda, C; Sardi, A; Sittig, M	1
Chou, WC; Kakadiya, R; Kuo, CY; Lee, TC; Su, TL; Wang, HC; Wong, TS; Wu, CC	1
Alevizos, L; Daskalou, T; Eleftheriadis, S; Iatrou, C; Korakianitis, O; Mavroudis, C; Stamou, K; Tentes, AA; Vogiatzaki, T	1
Alexandrov, VA; Belyaev, AM; Belyaeva, OA; Bespalov, VG; Kireeva, GS; Kopteva, OS; Krasilnikova, LA; Maidin, MA; Semenov, AL; Stukov, AN; Vasilieva, IN; Vyshinskaya, EA	1
Belmont-Díaz, JA; Cruz-Muñiz, MY; Franco-Cendejas, R; García-Contreras, R; Hernández-Durán, M; Licona-Limón, P; López-Jacome, LE; Martinéz-Vázquez, M; Ramos-Balderas, JL; Wood, TK	1
Barakova, NV; Bespalov, VG; Maidin, MA; Semenov, AL; Stukov, AN; Vasil'eva, IN; Vyshinskaya, EA	1
Bogner, S; Peis, MW; Reinboldt, MP; Schuler, M; Tewes, M; Theysohn, JM; Welt, A	1
Gushchin, V; King, MC; Nieroda, C; Sardi, A; Sipok, A; Sittig, M	1
Baron, E; Gushchin, V; King, MC; Lopez-Ramirez, F; Nieroda, C; Nikiforchin, A; Sardi, A	1

Reviews

9 review(s) available for mitomycin and melphalan

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Cytotoxic treatment of metastatic breast cancer. Which drugs and drug combinations to use? Acta oncologica (Stockholm, Sweden), 1992, Volume: 31, Issue:2 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Dactinomycin; Doxorubicin; Epirubicin; Etoposide; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Mitomycin; Mitoxantrone; Neoplasm Metastasis; Vincristine	1992
Metallothionein expression and transient resistance to electrophilic antineoplastic drugs. Seminars in cancer biology, 1991, Volume: 2, Issue:4 Topics: Animals; Antineoplastic Agents; Chlorambucil; Cisplatin; Cricetinae; Doxorubicin; Drug Resistance; Humans; Melphalan; Metallothionein; Mitomycin; Prednimustine	1991
[Chemotherapy of prostatic cancer]. Voprosy onkologii, 1985, Volume: 31, Issue:9 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Dacarbazine; Diethylstilbestrol; Doxorubicin; Estramustine; Fluorouracil; Humans; Hydroxyurea; Male; Melphalan; Methotrexate; Mitomycin; Mitomycins; Prednisolone; Procarbazine; Prostatic Neoplasms; Streptozocin; Vincristine	1985
Experience with mitomycin in the treatment of non-small cell lung cancer. Oncology, 1993, Volume: 50 Suppl 1 Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Humans; Lung Neoplasms; Melphalan; Methotrexate; Mitomycin; Mitomycins; Progesterone; Vinblastine	1993
Mitomycin: its evolving role in the treatment of breast cancer. Oncology, 1993, Volume: 50 Suppl 1 Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Melphalan; Methotrexate; Mitomycin; Mitomycins	1993
Phase I/II studies of isolated hepatic perfusion with mitomycin C or melphalan in patients with colorectal cancer hepatic metastases. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1998, Volume: 147 Topics: Animals; Antineoplastic Agents; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Colorectal Neoplasms; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Melphalan; Mitomycin; Perfusion; Rats	1998
NEW AND OLD DRUGS IN THE MANAGEMENT OF HODGKIN'S DISEASE. Medical times, 1964, Volume: 92 Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Bacterial Agents; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Dexamethasone; Folic Acid Antagonists; Hodgkin Disease; Humans; Isoniazid; Mannomustine; Melphalan; Methotrexate; Mitomycin; Mitomycins; Nitrogen Mustard Compounds; Phenylbutazone; Prednisolone; Prednisone; Thiotepa	1964
NEWER ANTICANCER AGENTS. The Medical clinics of North America, 1964, Volume: 48 Topics: Alkylating Agents; Antineoplastic Agents; Arsenicals; Cyclophosphamide; Dactinomycin; Fluorouracil; Humans; Mechlorethamine; Melphalan; Methotrexate; Mitomycin; Mitomycins; Neoplasms; Pharmacology; Steroids; Triethylenemelamine; Vinblastine; Vincristine	1964

Trials

7 trial(s) available for mitomycin and melphalan

Article	Year
Mitomycin: its evolving role in the treatment of breast cancer. Oncology, 1993, Volume: 50 Suppl 1 Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Melphalan; Methotrexate; Mitomycin; Mitomycins	1993
MMM (mitomycin/mitoxantrone/methotrexate): an effective new regimen in the treatment of metastatic breast cancer. Oncology, 1993, Volume: 50 Suppl 1 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; Humans; Melphalan; Menopause; Methotrexate; Middle Aged; Mitomycin; Neoplasm Metastasis; Neoplasm Staging; Vincristine	1993
Regional perfusion with hemofiltration (chemofiltration) for the treatment of patients with regionally advanced cancer. Cancer, 1996, Sep-01, Volume: 78, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Renal Cell; Chemotherapy, Cancer, Regional Perfusion; Cisplatin; Digestive System Neoplasms; Female; Fluorouracil; Genital Neoplasms, Female; Hemofiltration; Humans; Kidney Neoplasms; Male; Melanoma; Melphalan; Middle Aged; Mitomycin; Prognosis; Survival Rate	1996
Cardiovascular effects of simultaneous occlusion of the inferior vena cava and aorta in patients treated with hypoxic abdominal perfusion for chemotherapy. British journal of anaesthesia, 2002, Volume: 88, Issue:2 Topics: Aged; Antihypertensive Agents; Antineoplastic Combined Chemotherapy Protocols; Aorta, Thoracic; Chemotherapy, Cancer, Regional Perfusion; Constriction; Female; Hemodynamics; Humans; Hypertension; Male; Melphalan; Middle Aged; Mitomycin; Monitoring, Physiologic; Nitroprusside; Pancreatic Neoplasms; Vena Cava, Inferior	2002
Hypoxic pelvic and limb perfusion with melphalan and mitomycin C for recurrent limb melanoma: a pilot study. Melanoma research, 2003, Volume: 13, Issue:1 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional Perfusion; Disease Progression; Extremities; Female; Humans; Hypoxia; Male; Maximum Tolerated Dose; Melanoma; Melphalan; Middle Aged; Mitomycin; Neoplasm Recurrence, Local; Pilot Projects; Skin Neoplasms; Survival Rate; Time Factors	2003
Balloon catheter hypoxic abdominal perfusion with Mitomycin C and Melphalan for locally advanced pancreatic cancer: a phase I-II trial. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2004, Volume: 30, Issue:6 Topics: Aged; Antineoplastic Agents; Balloon Occlusion; Chemotherapy, Cancer, Regional Perfusion; Female; Humans; Hypoxia; Infusions, Intra-Arterial; Male; Melphalan; Middle Aged; Mitomycin; Pain; Pain Measurement; Pancreatic Neoplasms; Remission Induction; Treatment Outcome	2004
Balloon catheter hypoxic pelvic perfusion with mitomycin C and melphalan for locally advanced tumours in the pelvic region: a phase I-II trial. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2005, Volume: 31, Issue:8 Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Catheterization; Chemotherapy, Cancer, Regional Perfusion; Feasibility Studies; Female; Humans; Magnetic Resonance Imaging; Male; Melphalan; Middle Aged; Mitomycin; Neoadjuvant Therapy; Neoplasm Staging; Pain Measurement; Pelvic Neoplasms; Radiotherapy Dosage; Remission Induction; Survival Rate; Tomography, X-Ray Computed	2005

Other Studies

55 other study(ies) available for mitomycin and melphalan

Article	Year
Structure-activity relationships of antineoplastic agents in multidrug resistance. Journal of medicinal chemistry, 1990, Volume: 33, Issue:7 Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured	1990
Cell-based screen for identification of inhibitors of tubulin polymerization. Journal of natural products, 1996, Volume: 59, Issue:12 Topics: Animals; Brain Neoplasms; Bucladesine; Cell Differentiation; Drug Screening Assays, Antitumor; Formazans; Glioma; Rats; Tubulin; Tumor Cells, Cultured	1996
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations. European journal of medicinal chemistry, 2010, Volume: 45, Issue:4 Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water	2010
The use of ATP bioluminescence assays in selecting a drug screen panel for chemosensitivity testing of uterine cancer cell lines. Gynecologic oncology, 1992, Volume: 45, Issue:2 Topics: Adenocarcinoma; Adenosine Triphosphate; Alkaloids; Antineoplastic Agents; Cisplatin; Cyclophosphamide; Drug Screening Assays, Antitumor; Endometrial Neoplasms; Female; Humans; Intercalating Agents; Kinetics; Luminescent Measurements; Melphalan; Mitomycin; Tumor Cells, Cultured; Uterine Neoplasms	1992
Combination chemotherapy with mitomycin C, vindesine and melphalan for refractory metastatic breast cancer. Journal of cancer research and clinical oncology, 1991, Volume: 117, Issue:3 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Melphalan; Middle Aged; Mitomycin; Mitomycins; Neoplasm Metastasis; Palliative Care; Vindesine	1991
Isolation and characterization of nitrogen mustard-sensitive mutants of Chinese hamster ovary cells. Mutation research, 1991, Volume: 254, Issue:2 Topics: Aminacrine; Animals; Cells, Cultured; Cisplatin; Cricetinae; Cross Reactions; DNA; Dose-Response Relationship, Drug; Female; Gamma Rays; In Vitro Techniques; Mechlorethamine; Melphalan; Mitomycin; Mitomycins; Mutagens; Mutation; Nitrogen Mustard Compounds	1991
Changes in the proliferation of human lymphocytes induced by several cytostatics and revealed by the premature chromosome condensation technique. Mutation research, 1991, Volume: 263, Issue:2 Topics: Cell Cycle; Cell Fusion; Cell Line; Cells, Cultured; Chromosomes; Cisplatin; Cyclophosphamide; Humans; Lymphocyte Activation; Lymphocytes; Melphalan; Mitomycin; Mitomycins; Phytohemagglutinins	1991
[Sensitivity test of anti-tumor agents. 2. Application of MTT assay]. Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:10 Topics: Antineoplastic Agents; Cisplatin; Doxorubicin; Drug Screening Assays, Antitumor; Melphalan; Mitomycin; Mitomycins; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured	1991
Cross-sensitivity of gamma-ray-sensitive hamster mutants to cross-linking agents. Mutation research, 1991, Volume: 255, Issue:2 Topics: Animals; Camptothecin; Cell Line; Cell Survival; CHO Cells; Cisplatin; Cricetinae; Cricetulus; Cross-Linking Reagents; DNA Damage; Female; Guinea Pigs; Mechlorethamine; Melphalan; Mitomycin; Mutation; Radiation Tolerance; Ultraviolet Rays	1991
[A new in vitro chemosensitivity test. Individualized chemotherapy against ovarian cancer and its clinical effect]. Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:12 Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Child; Cisplatin; Colony-Forming Units Assay; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Nimustine; Nitrosourea Compounds; Ovarian Neoplasms; Tumor Stem Cell Assay	1985
[A study of the antineoplastic activity of K18]. Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:5 Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Line; Drug Combinations; Drug Synergism; Fluorouracil; gamma-Globulins; Humans; Immunotoxins; Melphalan; Mice; Mice, Nude; Mitomycin; Mitomycins; Neoplasm Transplantation; Stomach Neoplasms; Tissue Distribution	1986
[Systemically administered regional tumor therapy. Regional hemi-body chemotherapy of metastatic malignant melanoma--an experimental therapy concept]. Onkologie, 1989, Volume: 12, Issue:6 Topics: Adult; Antineoplastic Agents; Catheters, Indwelling; Chemotherapy, Cancer, Regional Perfusion; Cisplatin; Dose-Response Relationship, Drug; Extremities; Female; Heart-Lung Machine; Hemofiltration; Humans; Infusions, Intra-Arterial; Male; Melanoma; Melphalan; Mitomycin; Mitomycins; Neoplasm Metastasis; Pilot Projects; Skin Neoplasms	1989
[A new anti-cancer agent K-18 (conjugate of human IgG and melphalan). (II). Its inhibitory effects on in vitro DNA synthesis of human tumor cells]. Nihon Gan Chiryo Gakkai shi, 1986, Oct-20, Volume: 21, Issue:9 Topics: Antineoplastic Agents; Cells, Cultured; DNA, Neoplasm; Doxorubicin; Humans; Immunoglobulin G; Melphalan; Mitomycin; Mitomycins; Neoplasms	1986
Antineoplastic drug cytotoxicity in a human bladder cancer cell line: implications for intravesical chemotherapy. Urological research, 1987, Volume: 15, Issue:1 Topics: Administration, Intravesical; Antineoplastic Agents; Cell Survival; Cisplatin; Doxorubicin; Fluorouracil; Humans; In Vitro Techniques; Melphalan; Mitomycin; Mitomycins; Tumor Stem Cell Assay; Urinary Bladder Neoplasms; Vincristine	1987
Isolation of alkylating agent-sensitive Chinese hamster ovary cell lines. Carcinogenesis, 1987, Volume: 8, Issue:4 Topics: Alkylating Agents; Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; DNA Damage; DNA Repair; Ethyl Methanesulfonate; Ethylnitrosourea; Melphalan; Methylnitrosourea; Mitomycin; Mitomycins; Mutation	1987
[Application of cytopathology in a sensitivity test for anti-tumor agents. I. An experimental study]. Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:4 Topics: Animals; Antineoplastic Agents; Cisplatin; Colonic Neoplasms; Colony-Forming Units Assay; Cytological Techniques; Doxorubicin; Drug Evaluation, Preclinical; Female; Humans; Melphalan; Mice; Mitomycin; Mitomycins; Ovarian Neoplasms; Tumor Stem Cell Assay	1987
Complementation of DNA-repair deficiencies in Chinese hamster ovary cells. Biochemistry and cell biology = Biochimie et biologie cellulaire, 1987, Volume: 65, Issue:9 Topics: Aerobiosis; Anaerobiosis; Animals; Cell Line; Cell Survival; Cricetinae; DNA Repair; Gamma Rays; Genes; Genetic Complementation Test; Melphalan; Mitomycin; Mitomycins; Mutation; Ultraviolet Rays	1987
Prostaglandins act synergistically with antitumour agents on induction of sister chromatid exchanges in human lymphocytes. Prostaglandins, leukotrienes, and medicine, 1985, Volume: 17, Issue:1 Topics: Alprostadil; Antineoplastic Agents; Cells, Cultured; Dinoprost; Dinoprostone; Drug Synergism; Humans; Lymphocytes; Melphalan; Mitomycin; Mitomycins; Prostaglandins; Prostaglandins E; Prostaglandins F; Sister Chromatid Exchange	1985
In vitro evaluation of anticancer drugs against ovarian cancer at concentrations achievable by intraperitoneal administration. Seminars in oncology, 1985, Volume: 12, Issue:3 Suppl 4 Topics: Anthraquinones; Antineoplastic Agents; Cisplatin; Colony-Forming Units Assay; Cytarabine; Doxorubicin; Female; Fluorouracil; Humans; Infusions, Parenteral; Melphalan; Mitomycin; Mitomycins; Mitoxantrone; Ovarian Neoplasms; Peritoneal Cavity; Tumor Stem Cell Assay	1985
Melphalan-induced enhancement of tumor cell immunostimulatory capacity as a mechanism for the appearance of potent antitumor immunity in the spleen of mice bearing a large metastatic MOPC-315 tumor. Cancer immunology, immunotherapy : CII, 1985, Volume: 20, Issue:1 Topics: Animals; Cell Division; Cytotoxicity, Immunologic; Immunity, Cellular; Melphalan; Mice; Mitomycin; Mitomycins; Neoplasm Metastasis; Neoplasms, Experimental; Spleen	1985
Comparison of drug sensitivity among tumor cells within a tumor, between primary tumor and metastases, and between different metastases in the human tumor colony-forming assay. Cancer research, 1984, Volume: 44, Issue:6 Topics: Antineoplastic Agents; Bleomycin; Cell Division; Cell Survival; Cells, Cultured; Cisplatin; Doxorubicin; Fluorouracil; Humans; Kinetics; Male; Melphalan; Mitomycin; Mitomycins; Neoplasm Metastasis; Neoplasms	1984
Mitomycin C, melphalan and methotrexate combination chemotherapy for palliation of disseminated breast cancer. Cancer chemotherapy and pharmacology, 1984, Volume: 13, Issue:1 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Evaluation; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Melphalan; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Neoplasm Metastasis; Palliative Care	1984
Childhood rhabdomyosarcoma xenografts: responses to DNA-interacting agents and agents used in current clinical therapy. European journal of cancer & clinical oncology, 1984, Volume: 20, Issue:7 Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Line; Child; Cisplatin; Cyclophosphamide; Dacarbazine; Dactinomycin; Doxorubicin; Female; Humans; Melphalan; Mice; Mice, Inbred CBA; Mitomycin; Mitomycins; Neoplasm Transplantation; Rhabdomyosarcoma; Transplantation, Heterologous; Vincristine	1984
Melphalan-mediated potentiation of antitumor immune responsiveness of immunosuppressed spleen cells from mice bearing a large MOPC-315 tumor. Cancer immunology, immunotherapy : CII, 1984, Volume: 18, Issue:1 Topics: Animals; Antibiotics, Antineoplastic; Cell Line; Cytotoxicity, Immunologic; Female; Immunosuppression Therapy; Immunotherapy; Lymphocytes; Melphalan; Mice; Mice, Inbred BALB C; Mitomycin; Mitomycins; Plasmacytoma; Spleen	1984
Nitrogen mustard drug resistant B-cell chronic lymphocytic leukemia as an in vivo model for crosslinking agent resistance. Mutation research, 1995, Volume: 336, Issue:3 Topics: B-Lymphocytes; Chlorambucil; Cisplatin; Cross-Linking Reagents; DNA Adducts; DNA Damage; DNA Repair; DNA, Neoplasm; Drug Resistance; Humans; Inactivation, Metabolic; Leukemia, Lymphocytic, Chronic, B-Cell; Melphalan; Methyl Methanesulfonate; Mitomycin; Nitrogen Mustard Compounds; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured	1995
Low-dose melphalan-induced shift in the production of a Th2-type cytokine to a Th1-type cytokine in mice bearing a large MOPC-315 tumor. Cancer immunology, immunotherapy : CII, 1994, Volume: 39, Issue:2 Topics: Animals; Cytotoxicity, Immunologic; Dose-Response Relationship, Drug; Female; Immunocompromised Host; Interferon-gamma; Interleukin-10; Lymphocytes, Tumor-Infiltrating; Melphalan; Mice; Mice, Inbred BALB C; Mitomycin; Neoplasm Transplantation; Plasmacytoma; Spleen; Stimulation, Chemical; T-Lymphocytes; T-Lymphocytes, Cytotoxic; Tumor Cells, Cultured	1994
In vitro drug sensitivity testing can predict induction failure and early relapse of childhood acute lymphoblastic leukemia. Blood, 1997, Apr-15, Volume: 89, Issue:8 Topics: Aclarubicin; Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bleomycin; Bone Marrow; Cell Survival; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Follow-Up Studies; Humans; Infant; Infant, Newborn; Life Tables; Melphalan; Methotrexate; Mitomycin; Mitoxantrone; Neoplastic Stem Cells; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Recurrence; Remission Induction; Tumor Cells, Cultured; Vincristine	1997
[Glutathione levels in human colon cancer cell line M7609 following culture in a low sulfur amino acid medium and its sensitivity to various anticancer drugs]. Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:7 Topics: Amino Acids, Sulfur; Antineoplastic Agents; Cisplatin; Colonic Neoplasms; Culture Media; Doxorubicin; Glutathione; Humans; Melphalan; Mitomycin; Tumor Cells, Cultured	1997
Treatment of abdominal malignancies using total abdominal stop-flow infusion and hypoxic perfusion. Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:12 Topics: Abdominal Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Cisplatin; Doxorubicin; Female; Fluorouracil; Humans; Hypoxia; Melphalan; Mitomycin	1997
Isolated hypoxic hepatic perfusion with tumor necrosis factor-alpha, melphalan, and mitomycin C using balloon catheter techniques: a pharmacokinetic study in pigs. Annals of surgery, 1998, Volume: 228, Issue:6 Topics: Animals; Catheterization; Cell Hypoxia; Chemotherapy, Cancer, Regional Perfusion; Feasibility Studies; Liver; Melphalan; Mitomycin; Swine; Tissue Distribution; Tumor Necrosis Factor-alpha	1998
Potentiation of anti-cancer drug activity at low intratumoral pH induced by the mitochondrial inhibitor m-iodobenzylguanidine (MIBG) and its analogue benzylguanidine (BG). British journal of cancer, 1999, Volume: 79, Issue:5-6 Topics: 3-Iodobenzylguanidine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Antineoplastic Agents; Cell Division; Cell Survival; Chlorambucil; Chromium Radioisotopes; Doxorubicin; Drug Synergism; Edetic Acid; Glucose; Guanidines; Hydrogen-Ion Concentration; Kidney; Leukemia L1210; Melphalan; Mice; Mitomycin; Tumor Cells, Cultured	1999
Sensitivity to DNA cross-linking chemotherapeutic agents in mismatch repair-defective cells in vitro and in xenografts. International journal of cancer, 2000, Feb-15, Volume: 85, Issue:4 Topics: Adenosine Triphosphatases; Animals; Base Pair Mismatch; Burkitt Lymphoma; Cell Division; Cross-Linking Reagents; DNA Repair Enzymes; DNA-Binding Proteins; HeLa Cells; Humans; Lomustine; Melphalan; Mice; Mice, Knockout; Mice, Nude; Micronucleus Tests; Mismatch Repair Endonuclease PMS2; Mitomycin; MutS Homolog 2 Protein; Proteins; Proto-Oncogene Proteins; Transplantation, Heterologous; Tumor Cells, Cultured	2000
Theoretical considerations and in vitro concentration response studies with two human colorectal carcinoma cell lines. The rational experimental base for clinical studies in regional chemotherapy. Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:4 Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Carcinoma; Cisplatin; Colorectal Neoplasms; Doxorubicin; Epirubicin; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Melphalan; Mitomycin; Mitoxantrone; Tumor Cells, Cultured	2000
Melphalan and other anticancer modalities up-regulate B7-1 gene expression in tumor cells. Journal of immunology (Baltimore, Md. : 1950), 2000, Jun-15, Volume: 164, Issue:12 Topics: Animals; Antibiotics, Antineoplastic; Antigens, CD; Antineoplastic Agents, Alkylating; B7-1 Antigen; B7-2 Antigen; Cell Membrane; Drug Administration Schedule; Gamma Rays; Gene Expression Regulation, Neoplastic; Injections, Intraperitoneal; Mast-Cell Sarcoma; Melphalan; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mitomycin; Neoplasm Transplantation; Plasmacytoma; Protein Biosynthesis; Proteins; RNA; Tumor Cells, Cultured; Up-Regulation	2000
Continuous hyperthermic peritoneal perfusion (CHPP) for malignant ascites and irresectable intra-abdominal cancer. Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27 Suppl 2 Topics: Abdominal Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Ascites; Cell Division; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Humans; Hyperthermia, Induced; Infusions, Parenteral; Male; Melphalan; Middle Aged; Mitomycin; Perfusion; Survival Rate	2000
Phase II trials of mitomycin C, AB-100, NSC-1026, L-sarcolysin, and meta-sarcolysin, in the treatment of multiple myeloma. Cancer chemotherapy reports, 1962, Volume: 16 Topics: Anti-Bacterial Agents; Antineoplastic Agents; Cell- and Tissue-Based Therapy; Cycloleucine; Cycloparaffins; Melphalan; Mitomycin; Multiple Myeloma; Plasma; Plasma Cells	1962
CHEMOTHERAPY STUDIES ON PRIMARY TUMOR GRAFTS AND METASTASES IN HAMSTERS AND MICE. Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20 Topics: Antineoplastic Agents; Cricetinae; Cyclophosphamide; Dactinomycin; Melphalan; Mice; Mitomycin; Mitomycins; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Pharmacology; Research; Sarcoma; Sarcoma, Experimental; Thiotepa	1964
INTERACTION BETWEEN 5-HYDROXYTRYPTAMINE AND ANTITUMOURAL DRUGS. The Journal of pharmacy and pharmacology, 1964, Volume: 16 Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cyclophosphamide; Fluorouracil; Melphalan; Mice; Mitomycin; Mitomycins; Nitrogen Mustard Compounds; Pharmacology; Research; Sarcoma 180; Serotonin; Toxicology; Triethylenemelamine	1964
Significance of postoperative adjuvant immunochemotherapy after curative resection of colorectal cancers: identification of responders incorporating the age factor. Oncology reports, 2004, Volume: 11, Issue:3 Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; CA-19-9 Antigen; Carcinoembryonic Antigen; Chemotherapy, Adjuvant; Colonic Neoplasms; Complement C3; Complement C4; Female; Fluorouracil; Humans; Immunotherapy; Lymphocyte Activation; Male; Medroxyprogesterone Acetate; Melphalan; Middle Aged; Mitomycin; Multivariate Analysis; Neoplasm Proteins; Phytohemagglutinins; Prognosis; Proportional Hazards Models; Proteoglycans; Pyrimidines; Time Factors; Treatment Outcome	2004
Dependence of the cytotoxicity of DNA-damaging agents on the mismatch repair status of human cells. Cancer research, 2004, May-15, Volume: 64, Issue:10 Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Base Pair Mismatch; Camptothecin; Carrier Proteins; Cell Line; Cisplatin; DNA Repair; Drug Screening Assays, Antitumor; Etoposide; Furocoumarins; Humans; Inhibitory Concentration 50; Melphalan; Mitomycin; MutL Protein Homolog 1; Neoplasm Proteins; Nitrosourea Compounds; Nuclear Proteins	2004
Balloon catheter hypoxic abdominal and pelvic perfusion with tumour necrosis factor-alpha, Melphalan and Mitomycin C: a pharmacokinetic study in pigs. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2004, Volume: 30, Issue:6 Topics: Abdominal Neoplasms; Animals; Antineoplastic Agents; Balloon Occlusion; Chemotherapy, Cancer, Regional Perfusion; Hypoxia; Melphalan; Mitomycin; Models, Animal; Pelvic Neoplasms; Swine; Tumor Necrosis Factor-alpha	2004
In vivo therapeutic responses contingent on Fanconi anemia/BRCA2 status of the tumor. Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Oct-15, Volume: 11, Issue:20 Topics: Animals; Antineoplastic Agents; Apoptosis; BRCA2 Protein; Caspases; Cell Cycle; Cell Line, Tumor; Cell Survival; Chlorambucil; Cisplatin; Cross-Linking Reagents; Deoxycytidine; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Fanconi Anemia Complementation Group C Protein; Fanconi Anemia Complementation Group G Protein; Fanconi Anemia Complementation Group Proteins; Female; Fluorouracil; Gemcitabine; Humans; Inhibitory Concentration 50; Melphalan; Mice; Mice, Nude; Mitomycin; Mutation; Paclitaxel; Pancreatic Neoplasms; Time Factors; Vinblastine; Xenograft Model Antitumor Assays	2005
Multiple repair pathways mediate tolerance to chemotherapeutic cross-linking agents in vertebrate cells. Cancer research, 2005, Dec-15, Volume: 65, Issue:24 Topics: Animals; Antigens, Nuclear; Antineoplastic Agents, Alkylating; Chickens; Cisplatin; Cross-Linking Reagents; DNA; DNA Damage; DNA Repair; DNA Replication; DNA-Binding Proteins; DNA-Directed DNA Polymerase; Epistasis, Genetic; Fanconi Anemia Complementation Group C Protein; Genes, rev; Ku Autoantigen; Melphalan; Mitomycin; Nucleic Acid Synthesis Inhibitors; Recombination, Genetic; Signal Transduction	2005
Heterogeneous activity of cytotoxic drugs in patient samples of peritoneal carcinomatosis. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2008, Volume: 34, Issue:5 Topics: Camptothecin; Cisplatin; Cytotoxins; Doxorubicin; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Irinotecan; Male; Melphalan; Mitomycin; Organoplatinum Compounds; Oxaliplatin; Perioperative Care; Peritoneal Neoplasms; Tumor Cells, Cultured	2008
Therapeutic isolated limb perfusion (ILP) in the management of patients with advanced or recurrent limb melanoma. Irish journal of medical science, 2012, Volume: 181, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional Perfusion; Humans; Lower Extremity; Melanoma; Melphalan; Mitomycin; Neoplasm Recurrence, Local; Skin Neoplasms; Upper Extremity	2012
Repeated cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in peritoneal carcinomatosis from appendiceal cancer: analysis of survival outcomes. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2013, Volume: 39, Issue:11 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Carboplatin; Carcinoma; Chemotherapy, Adjuvant; Databases, Factual; Digestive System Surgical Procedures; Female; Humans; Hyperthermia, Induced; Infusions, Parenteral; Kaplan-Meier Estimate; Length of Stay; Male; Melphalan; Middle Aged; Mitomycin; Peritoneal Neoplasms; Reoperation; Retrospective Studies; Treatment Outcome	2013
Repairing of N-mustard derivative BO-1055 induced DNA damage requires NER, HR, and MGMT-dependent DNA repair mechanisms. Oncotarget, 2015, Sep-22, Volume: 6, Issue:28 Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Ataxia Telangiectasia Mutated Proteins; Cell Death; CHO Cells; Cricetulus; DNA Damage; DNA Modification Methylases; DNA Repair; DNA Repair Enzymes; Dose-Response Relationship, Drug; Drug Synergism; HEK293 Cells; Humans; MCF-7 Cells; Melphalan; Mitomycin; Nitrogen Mustard Compounds; Phenylurea Compounds; Protein Kinase Inhibitors; Recombinational DNA Repair; RNA Interference; S Phase Cell Cycle Checkpoints; Signal Transduction; Time Factors; Transfection; Tumor Suppressor Proteins	2015
Lack of significant intraoperative coagulopathy in patients undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) indicates that epidural anaesthesia is a safe option. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 2015, Volume: 31, Issue:8 Topics: Adult; Aged; Analgesia, Epidural; Antineoplastic Agents; Blood Coagulation; Cisplatin; Combined Modality Therapy; Cytoreduction Surgical Procedures; Deoxycytidine; Doxorubicin; Female; Fibrinogen; Gemcitabine; Humans; Hyperthermia, Induced; Integrin beta3; Male; Melphalan; Middle Aged; Mitomycin; Peritoneal Neoplasms; Platelet Count; Platelet Glycoprotein GPIb-IX Complex; Young Adult	2015
[Intraperitoneal chemotherapy--a method of improving treatment effectiveness in ovarian cancer]. Voprosy onkologii, 2015, Volume: 61, Issue:4 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Deoxycytidine; Female; Gemcitabine; Infusions, Intravenous; Infusions, Parenteral; Maximum Tolerated Dose; Melphalan; Mitomycin; Ovarian Neoplasms; Paclitaxel; Peritoneal Neoplasms; Rats; Rats, Wistar; Triazines	2015
Repurposing the anticancer drug mitomycin C for the treatment of persistent Acinetobacter baumannii infections. International journal of antimicrobial agents, 2017, Volume: 49, Issue:1 Topics: Acinetobacter baumannii; Acinetobacter Infections; Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Cisplatin; Disease Models, Animal; Drug Repositioning; Fluorouracil; Larva; Lepidoptera; Melphalan; Microbial Sensitivity Tests; Microbial Viability; Mitomycin; Survival Analysis; Treatment Outcome	2017
Comparative Study of Antitumor Efficiency of Intraperitoneal and Intravenous Cytostatics in Experimental Rats with Disseminated Ovarian Cancer. Bulletin of experimental biology and medicine, 2017, Volume: 162, Issue:3 Topics: Adenocarcinoma, Papillary; Animals; Antineoplastic Agents; Ascites; Cisplatin; Female; Injections, Intraperitoneal; Injections, Intravenous; Melphalan; Mitomycin; Neoplasm Transplantation; Ovarian Neoplasms; Paclitaxel; Rats; Survival Analysis; Treatment Outcome; Triazines	2017
Hepatic arterial infusion chemotherapy for extensive liver metastases of breast cancer: efficacy, safety and prognostic parameters. Journal of cancer research and clinical oncology, 2017, Volume: 143, Issue:10 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Melphalan; Middle Aged; Mitomycin; Retrospective Studies; Salvage Therapy	2017
Comparison of Survival in Patients with Isolated Peritoneal Carcinomatosis from Colorectal Cancer Treated with Cytoreduction and Melphalan or Mitomycin-C as Hyperthermic Intraperitoneal Chemotherapy Agent. International journal of surgical oncology, 2018, Volume: 2018 Topics: Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Combined Modality Therapy; Cytoreduction Surgical Procedures; Female; Humans; Hyperthermia, Induced; Male; Melphalan; Middle Aged; Mitomycin; Peritoneal Neoplasms; Retrospective Studies; Survival Rate; United States	2018
Safety of Nephrectomy Performed During CRS/HIPEC: A Propensity Score-Matched Study. Annals of surgical oncology, 2023, Volume: 30, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytoreduction Surgical Procedures; Humans; Hyperthermia, Induced; Hyperthermic Intraperitoneal Chemotherapy; Melphalan; Mitomycin; Nephrectomy; Peritoneal Neoplasms; Propensity Score; Retrospective Studies; Survival Rate	2023