Page last updated: 2024-08-16

mitomycin and dacarbazine

mitomycin has been researched along with dacarbazine in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199011 (45.83)18.7374
1990's3 (12.50)18.2507
2000's4 (16.67)29.6817
2010's6 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Benfenati, E; Raska, I; Toropov, AA; Toropova, AP1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Droz, JP; Herait, P; Kac, JL; Rougier, P; Theodore, C1
Portnoĭ, AS1
Burgess, M; Pasterz, R; Savaraj, N1
Voigt, H1
Falkson, G; Falkson, HC; Pretorius, HL; Schoeman, HS1
Evans, M; Hellmann, K; Jones, R; Newton, K; Peters, N; Phillips, RH; Smith, BJ1
Cook, RL; Houghton, JA; Houghton, PJ; Lutz, PJ1
Cassady, JR; Frantz, CN; Kretschmar, C; Levey, R; Rosen, EM; Sallan, SE; Vawter, G1
Brodsky, I; Bulova, SI; Conroy, JF; Kahn, SB; Pequignot, E; Roda, PI1
Campbell, ED; Carter, WH; Stablein, DM; Wampler, GL1
Belliveau, JF; Darnowski, JW; Leenen, L; Turk, PS; Wanebo, HJ; Weinberg, MC1
Dispenzieri, A; Loprinzi, CL1
Allan, JM; Broekhof, JL; Carls, NH; Donker, I; Engelward, BP; Glassner, BJ; Hampson, RJ; Hersmus, R; Hickman, MJ; Hoeijmakers, JH; Roth, RB; Samson, LD; Warren, HB; Weeda, G; Wu, MM1
Buckner, JC; Edmonson, JH; Mahoney, MR; Marks, RS1
Cupissol, D; Cuq, P; Depeille, P; Evrard, A; Passagne, I; Vian, L1
Blessing, JA; Long, HJ; Sorosky, J1
Fabian, K; Kaina, B; Thacker, J; Tsaryk, R1
Aydincak, O; Baykaner, K; Emmez, H; Kurt, G; Memis, L; Sepici, A; Yilmaz, MB1

Reviews

2 review(s) available for mitomycin and dacarbazine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Chemotherapy of prostatic cancer].
    Voprosy onkologii, 1985, Volume: 31, Issue:9

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Dacarbazine; Diethylstilbestrol; Doxorubicin; Estramustine; Fluorouracil; Humans; Hydroxyurea; Male; Melphalan; Methotrexate; Mitomycin; Mitomycins; Prednisolone; Procarbazine; Prostatic Neoplasms; Streptozocin; Vincristine

1985

Trials

2 trial(s) available for mitomycin and dacarbazine

ArticleYear
Contrast of response to dacarbazine, mitomycin, doxorubicin, and cisplatin (DMAP) plus GM-CSF between patients with advanced malignant gastrointestinal stromal tumors and patients with other advanced leiomyosarcomas.
    Cancer investigation, 2002, Volume: 20, Issue:5-6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Doxorubicin; Female; Gastrointestinal Neoplasms; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Infusions, Intravenous; Leiomyosarcoma; Male; Middle Aged; Mitomycin; Survival Analysis; Treatment Outcome; Uterine Neoplasms

2002
Phase II trial of dacarbazine, mitomycin, doxorubicin, and cisplatin with sargramostim in uterine leiomyosarcoma: a Gynecologic Oncology Group study.
    Gynecologic oncology, 2005, Volume: 99, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dacarbazine; Doxorubicin; Drug Administration Schedule; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leiomyosarcoma; Leukopenia; Middle Aged; Mitomycin; Recombinant Proteins; Uterine Neoplasms

2005

Other Studies

20 other study(ies) available for mitomycin and dacarbazine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:4

    Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Alternating 5-FU-mitomycin C/5-FU-dacarbazine in advanced colorectal adenocarcinoma: a phase II study.
    Oncology, 1989, Volume: 46, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dacarbazine; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Humans; Male; Middle Aged; Mitomycin; Mitomycins

1989
Prognostic factors in metastatic carcinoma of unknown primary.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:11

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Cyclophosphamide; Dacarbazine; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Mitomycin; Mitomycins; Neoplasms, Unknown Primary; Prognosis; Skin Neoplasms; Statistics as Topic; Tegafur; Vincristine

1986
Age and dose of chemotherapy as major prognostic factors in a trial of adjuvant therapy of osteosarcoma combining two alternating drug combinations and early prophylactic lung irradiation. French Bone Tumor Study Group.
    Cancer, 1988, Apr-01, Volume: 61, Issue:7

    Topics: Adolescent; Adult; Aging; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Combined Modality Therapy; Cyclophosphamide; Dacarbazine; Doxorubicin; Female; Femoral Neoplasms; Fibula; Humans; Humerus; Lung Neoplasms; Male; Methotrexate; Mitomycin; Mitomycins; Osteosarcoma; Prognosis; Radiotherapy Dosage; Tibia; Time Factors; Vincristine

1988
[Regional intra-arterial chemotherapy].
    Deutsche medizinische Wochenschrift (1946), 1988, Jul-15, Volume: 113, Issue:28-29

    Topics: Cisplatin; Dacarbazine; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Melanoma; Mitomycin; Mitomycins

1988
Combination of dacarbazine, mitomycin C, 5-fluorouracil and vincristine in advanced colorectal cancer.
    Cancer chemotherapy and pharmacology, 1983, Volume: 11, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Dacarbazine; Female; Fluorouracil; Humans; Male; Middle Aged; Mitomycin; Mitomycins; Rectal Neoplasms; Vincristine

1983
Inefficacy of dacarbazine, mitomycin C, and hepatic irradiation in patients with metastatic adenocarcinoma of the gastrointestinal tract.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Dacarbazine; Gastrointestinal Neoplasms; Humans; Liver Neoplasms; Middle Aged; Mitomycin; Mitomycins

1984
Childhood rhabdomyosarcoma xenografts: responses to DNA-interacting agents and agents used in current clinical therapy.
    European journal of cancer & clinical oncology, 1984, Volume: 20, Issue:7

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Line; Child; Cisplatin; Cyclophosphamide; Dacarbazine; Dactinomycin; Doxorubicin; Female; Humans; Melphalan; Mice; Mice, Inbred CBA; Mitomycin; Mitomycins; Neoplasm Transplantation; Rhabdomyosarcoma; Transplantation, Heterologous; Vincristine

1984
Improved survival in neuroblastoma using multimodality therapy.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1984, Volume: 2, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dacarbazine; Doxorubicin; Drug Administration Schedule; Humans; Infant; Mechlorethamine; Mitomycin; Mitomycins; Neuroblastoma; Prognosis; Radiotherapy, High-Energy; Vincristine

1984
Efficacy of dacarbazine imidazole carboxamide and mitomycin C combination therapy in patients with adenocarcinoma of the colon refractory to 5-fluorouracil therapy.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1981, Volume: 79

    Topics: Adenocarcinoma; Colonic Neoplasms; Dacarbazine; Drug Resistance; Drug Therapy, Combination; Female; Fluorouracil; Humans; Liver Neoplasms; Middle Aged; Mitomycin; Mitomycins; Neoplasm Metastasis; Radionuclide Imaging; Time Factors

1981
Drug activity and therapeutic synergism in cancer treatment.
    Cancer research, 1982, Volume: 42, Issue:8

    Topics: Animals; Antineoplastic Agents; Dacarbazine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Humans; Hydroxamic Acids; Lung Neoplasms; Male; Melanoma; Mice; Mitomycin; Mitomycins; Neoplasms; Neoplasms, Experimental; Rats; Razoxane; Teniposide

1982
Isolated pelvic perfusion for unresectable cancer using a balloon occlusion technique.
    Archives of surgery (Chicago, Ill. : 1960), 1993, Volume: 128, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Catheterization; Chemotherapy, Cancer, Regional Perfusion; Cisplatin; Dacarbazine; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Melanoma; Middle Aged; Mitomycin; Neoplasm Recurrence, Local; Palliative Care; Pelvis; Rectal Neoplasms; Remission Induction

1993
Chemotherapy-induced insulin-dependent diabetes mellitus.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:3

    Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dacarbazine; Dexamethasone; Diabetes Mellitus, Type 1; Doxorubicin; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Jejunal Neoplasms; Leiomyosarcoma; Male; Middle Aged; Mitomycin

1997
DNA repair methyltransferase (Mgmt) knockout mice are sensitive to the lethal effects of chemotherapeutic alkylating agents.
    Mutagenesis, 1999, Volume: 14, Issue:3

    Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Carcinogens; Carmustine; Dacarbazine; Genotype; Hematopoietic System; Liver; Methylnitronitrosoguanidine; Mice; Mice, Knockout; Mitomycin; Models, Biological; O(6)-Methylguanine-DNA Methyltransferase; Streptozocin; Temozolomide

1999
O(6)-methylguanine DNA-methyltransferase (MGMT) overexpression in melanoma cells induces resistance to nitrosoureas and temozolomide but sensitizes to mitomycin C.
    Toxicology and applied pharmacology, 2006, Mar-01, Volume: 211, Issue:2

    Topics: Antineoplastic Agents; Buthionine Sulfoximine; Cell Line, Tumor; Cell Survival; Dacarbazine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Inhibitory Concentration 50; Melanoma; Mitomycin; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Temozolomide; Transfection

2006
Xrcc2 deficiency sensitizes cells to apoptosis by MNNG and the alkylating anticancer drugs temozolomide, fotemustine and mafosfamide.
    Cancer letters, 2006, Aug-08, Volume: 239, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Cisplatin; Cyclophosphamide; Dacarbazine; DNA-Binding Proteins; Humans; Methylnitronitrosoguanidine; Mitomycin; Mutagens; Nitrosourea Compounds; Organophosphorus Compounds; Temozolomide

2006
The effect of temozolomide on the prevention of epidural fibrosis developing after lumbar laminectomy in rats.
    Turkish neurosurgery, 2012, Volume: 22, Issue:6

    Topics: Animals; Dacarbazine; Dura Mater; Epidural Space; Fibroblasts; Fibrosis; Laminectomy; Lumbar Vertebrae; Male; Mitomycin; Rats; Rats, Wistar; Temozolomide

2012