mitomycin has been researched along with colchicine in 79 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 14 (17.72) | 18.7374 |
1990's | 33 (41.77) | 18.2507 |
2000's | 17 (21.52) | 29.6817 |
2010's | 14 (17.72) | 24.3611 |
2020's | 1 (1.27) | 2.80 |
Authors | Studies |
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Hansch, C; Khwaja, TA; Selassie, CD | 1 |
Barrows, LR; Ireland, CM; Kokoshka, JM | 1 |
Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Cheng, J; Liang, Y; Lin, S; Pan, F; Wang, Y | 1 |
Kamikawaji, N; Kimura, A; Nishimura, Y; Odum, N; Okamoto, Y; Sasazuki, T; Yoshizumi, H | 1 |
Majone, F; Panozzo, M; Soligo, C; Tonetto, S | 1 |
Deleener, A; Kirsch-Volders, M; Van Hummelen, P; Vanparys, P | 1 |
Hashida, M; Mihara, K; Nakane, S; Nishida, K; Sezaki, H; Takakura, Y; Takino, T | 1 |
Sato, S; Sutou, S | 1 |
Henika, PR; MacGregor, JT; Shelby, MD; Wehr, CM | 1 |
Brunetti, R; Fumagalli, O; Gabriele, M; Levis, AG; Majone, F | 1 |
Sysmans, M; Temmerman, R; Vanparys, P; Vermeiren, F | 1 |
Adler, ID; Miller, BM | 1 |
Chao, CC; Cheng, PW; Lin-Chao, S; Ma, CM | 1 |
Matthews, N; Neale, ML | 1 |
Furukawa-Nakanishi, K; Kobayashi, Y; Miyamoto, D; Osada, H; Osawa, T | 1 |
Wilkinson, PC | 1 |
Austgulen, R; Kildahl-Andersen, O; Nissen-Meyer, J | 1 |
Calissano, P; Coccia, EM; Di Luzio, A; Improta, T; Romeo, G; Salvatore, AM | 1 |
Campos, A; Goyanes, VJ; Lage, AM; Ramos, S; Schvartzman, JB; Silva, MC; Veiras, C | 1 |
Cone, RE; Emerson, SG; Pretell, J | 1 |
MacGregor, JT; Schlegel, R | 1 |
Huntenburg, CC; Kurimoto, S; Ohkubo, K; Yokoyama, MM | 1 |
Alfonso, M; Coll, J; Segarra, M; Subiza, JL | 1 |
Higashikuni, N; Sutou, S | 1 |
Hayashi, M; Honma, M; Mäki-Paakkanen, J; Matsuoka, A; Mizusawa, H; Sofuni, T; Suzuki, T; Tanabe, H | 1 |
Honda, M; Kuramochi, T; Morioka, S; Tanaka, K | 1 |
Lynch, AM; Parry, JM | 1 |
Antoccia, A; Degrassi, F; Modesti, D; Tanzarella, C | 1 |
Antoccia, A; Creus, A; Degrassi, F; Marcos, R; Peris, F; Surrallés, J; Tanzarella, C; Xamena, N | 1 |
Adler, ID; Beisker, W; Cao, J; Nüsse, M | 1 |
Elhajouji, A; Kirsch-Volders, M; Van Hummelen, P | 1 |
Hayashi, M; Honma, M; Mäki-Paakkanen, J; Sofuni, T; Suzuki, T; Tanabe, H | 1 |
Bastianelli, R; Meschini, R; Palitti, F | 1 |
Chao, CC | 1 |
Hoheneder, A; Veltel, D | 1 |
Ludwicki, JK; Tyrkiel, E; Wiadrowska, B | 1 |
Hibino, Y; Komae, N; Narita, H; Sugano, N | 1 |
Asanami, S; Shimono, K | 2 |
Izumiyama, F; Matsusaka, N; Nishidate, E; Sasaki, YF; Tsuda, S | 1 |
Glatt, HR; Hayashi, M; Matsuoka, A; Ozaki, M; Sakamoto, H; Sofuni, T; Takeshita, K | 1 |
Cunha, M; Elhajouji, A; Kirsch-Volders, M | 1 |
Chen, JK; Liu, YG; Wu, ZL | 1 |
Armstrong, MJ; Galloway, SM; Sun, JT | 1 |
Ayllon, F; Garcia-Vazquez, E | 2 |
Gil, L; Martínez Morillo, M; Ruiz Gómez, MJ; Souviron, A | 1 |
Jia, C; Jie, YM | 1 |
Gil, L; Martínez-Morillo, M; Ruiz-Gómez, MJ; Souviron, A | 1 |
Dusitsin, N; Posayanonda, T; Sindhuphak, R; Sinhaseni, P; Suramana, T | 1 |
Adler, ID; Attia, SM; Badary, OA; Hamada, FM; Kliesch, U; Schriever-Schwemmer, G | 1 |
GOLDENBERG, DM | 1 |
KANTNER, V; SCHWARTZ, E | 1 |
JOKLIK, WK | 1 |
Berti, F; Cantelli-Forti, G; Fimognari, C; Hrelia, P | 1 |
DEYSSON, G; DEYSSON, M | 1 |
Asano, N; Dertinger, SD; Hayashi, M; Morita, T; Tometsko, CR; Torous, DK | 1 |
Aardema, MJ; Lorenzon, G; Lorge, E; Marzin, D; Oliver, J; Thybaud, V; Wakata, A | 1 |
Fellows, MD; O'Donovan, MR | 1 |
Jiang, YZ; Liu, YK; Lu, SL; Wang, XQ; Wang, ZY | 1 |
Eliashar, R; Hirshoren, N | 1 |
Mabeta, P; Pepper, MS | 1 |
Attia, SM | 3 |
Liu, YK; Lu, SL; Qing, C; Wang, XQ | 1 |
Fowler, P; Jeffrey, L; Kirkland, D; Smith, K; Whitwell, J; Young, J | 1 |
Elhajouji, A | 1 |
Kirchner, S; Zeller, A | 1 |
Ashour, AE; Attia, SM; Bakheet, SA | 1 |
Harada, A; Katoh, C; Matsuzaki, K; Mishima, M; Motoyama, S; Takeiri, A; Taketo, J; Tanaka, K | 1 |
Chocian, K; Clatworthy, M; Doak, S; Doherty, AT; Jenkins, G; Molloy, J; O'Donovan, M; Wilson, A | 1 |
Akaishi, T; Kokubun, T; Nakamura, M; Nakazawa, T; Omodaka, K; Sato, K; Shiga, Y; Shimazaki, A; Tsuda, S; Yamamoto, K | 1 |
4 review(s) available for mitomycin and colchicine
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Antimitotic drug injections and radiotherapy: a review of the effectiveness of treatment for hypertrophic scars and keloids.
Topics: Adrenal Cortex Hormones; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antimitotic Agents; Cicatrix, Hypertrophic; Colchicine; Fluorouracil; Humans; Keloid; Keratolytic Agents; Mitomycin; Radiotherapy; Tretinoin; Tubulin Modulators | 2008 |
Wound-healing modulation in upper airway stenosis-Myths and facts.
Topics: Acetylcysteine; Aminopropionitrile; Animals; Antimetabolites; Colchicine; Fluorouracil; Humans; Hyperbaric Oxygenation; Laryngostenosis; Mitomycin; Nucleic Acid Synthesis Inhibitors; Piperidines; Protein Synthesis Inhibitors; Quinazolinones; Secondary Prevention; Wound Healing | 2009 |
A review of the effectiveness of antimitotic drug injections for hypertrophic scars and keloids.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Bleomycin; Cicatrix, Hypertrophic; Colchicine; Drug Therapy, Combination; Fibroblasts; Fluorouracil; Glucocorticoids; Humans; Injections, Intralesional; Keloid; Mitomycin; Mitosis Modulators; Treatment Outcome; Tretinoin; Triamcinolone | 2009 |
75 other study(ies) available for mitomycin and colchicine
Article | Year |
---|---|
Structure-activity relationships of antineoplastic agents in multidrug resistance.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured | 1990 |
Cell-based screen for identification of inhibitors of tubulin polymerization.
Topics: Animals; Brain Neoplasms; Bucladesine; Cell Differentiation; Drug Screening Assays, Antitumor; Formazans; Glioma; Rats; Tubulin; Tumor Cells, Cultured | 1996 |
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies.
Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Novel diaryl-2H-azirines: Antitumor hybrids for dual-targeting tubulin and DNA.
Topics: Animals; Antineoplastic Agents; Apoptosis; Azirines; Cell Line, Tumor; Cell Proliferation; DNA; DNA Damage; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Polymerization; Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2021 |
Signal transduction by HLA class II molecules in human T cells: induction of LFA-1-dependent and independent adhesion.
Topics: Alkaloids; Antigens, CD; Aphidicolin; Benzoquinones; Cell Adhesion; Cell Line; Colchicine; Cold Temperature; Cytochalasin B; Cytochalasins; Dideoxyadenosine; Dose-Response Relationship, Drug; Edetic Acid; HLA-DR Antigens; Humans; Lactams, Macrocyclic; Lymphocyte Function-Associated Antigen-1; Mitomycin; Protein Kinase C; Protein-Tyrosine Kinases; Quinones; Rifabutin; Signal Transduction; Staurosporine; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1992 |
Identification of kinetochores and DNA synthesis in micronuclei induced by mitomycin C and colchicine in Chinese hamster ovary cells.
Topics: Animals; Cell Cycle; Centromere; CHO Cells; Chromosomes; Colchicine; Cricetinae; DNA Replication; In Vitro Techniques; Micronuclei, Chromosome-Defective; Mitomycin; S Phase | 1992 |
Discrimination of aneuploidogens from clastogens by C-banding, DNA and area measurements of micronuclei from mouse bone marrow.
Topics: Aneuploidy; Animals; Azacitidine; Azathioprine; Bone Marrow; Chromosome Banding; Colchicine; Dioxolanes; DNA; Ethyl Methanesulfonate; Female; Hydroquinones; Male; Mice; Micronucleus Tests; Mitomycin; Mutagens; Procarbazine; Vinblastine | 1992 |
Hepatic disposition characteristics of electrically charged macromolecules in rat in vivo and in the perfused liver.
Topics: Animals; Anions; Cations; Colchicine; Cytochalasin B; Dextrans; Liver; Macromolecular Substances; Male; Mitomycin; Mitomycins; Perfusion; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Temperature | 1991 |
Maternal effect on micronucleus induction in MS/Ae mice.
Topics: Animals; Animals, Newborn; Cell Differentiation; Colchicine; Extrachromosomal Inheritance; Female; Litter Size; Male; Mercaptopurine; Mice; Mice, Inbred Strains; Micronucleus Tests; Mitomycin; Mitomycins; Pregnancy | 1990 |
The in vivo erythrocyte micronucleus test: measurement at steady state increases assay efficiency and permits integration with toxicity studies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzene; Bone Marrow; Bone Marrow Cells; Butadienes; Colchicine; Diet; Erythrocytes; Male; Mice; Mice, Inbred Strains; Micronucleus Tests; Mitomycin; Mitomycins; Monocrotaline; Plants, Toxic; Pyrrolizidine Alkaloids; Triethylenemelamine; Urethane | 1990 |
Induction of micronuclei by mitomycin C and colchicine in the marine mussel Mytilus galloprovincialis.
Topics: Animals; Bivalvia; Chromosome Aberrations; Colchicine; Micronucleus Tests; Mitomycin; Mitomycins; Time Factors | 1990 |
The micronucleus assay as a test for the detection of aneugenic activity.
Topics: Aneuploidy; Animals; Azathioprine; Bone Marrow; Cell Division; Colchicine; Cyclophosphamide; Dioxolanes; Erythrocytes; Female; Male; Mice; Miconazole; Micronucleus Tests; Microtubules; Mitomycin; Mitomycins; Procarbazine; Vinblastine | 1990 |
Application of antikinetochore antibody staining (CREST staining) to micronuclei in erythrocytes induced in vivo.
Topics: Alkylating Agents; Animals; Bone Marrow Cells; Chromosome Aberrations; Chromosomes; Colchicine; Erythrocytes; Fluorescent Antibody Technique; Male; Mice; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mitomycin; Mitomycins; Scleroderma, Systemic | 1990 |
Increased mdr gene expression and decreased drug accumulation in a human colonic cancer cell line resistant to hydrophobic drug.
Topics: Antineoplastic Agents; Base Sequence; Biological Transport; Blotting, Northern; Blotting, Southern; Cell Line; Cisplatin; Colchicine; Colonic Neoplasms; DNA, Neoplasm; Doxorubicin; Drug Resistance; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Mitomycin; Mitomycins; Puromycin; RNA, Messenger; Vinblastine | 1990 |
Development of tumour cell resistance to tumour necrosis factor does not confer resistance to cytotoxic drugs.
Topics: Animals; Cell Line; Cell Survival; Colchicine; Colony-Forming Units Assay; Dactinomycin; Daunorubicin; Drug Resistance; Humans; Mice; Mitomycin; Mitomycins; Rabbits; Tumor Necrosis Factor-alpha; Vincristine | 1989 |
Partial purification of a macrophage-activating factor for glucose consumption (MAF-G) produced by a human T-cell hybridoma and its relation to a growth-promoting factor.
Topics: Animals; Chromatography, Gel; Colchicine; Glucose; Growth Substances; Guinea Pigs; Humans; Hybridomas; In Vitro Techniques; Isoelectric Point; Lymphokines; Macrophage Activation; Macrophage-Activating Factors; Mitomycin; Mitomycins; Monocytes; T-Lymphocytes | 1989 |
The locomotor capacity of human lymphocytes and its enhancement by cell growth.
Topics: Autoradiography; Cell Movement; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Colchicine; Cycloheximide; DNA; Humans; Interleukin-8; Leucine; Lymphocytes; Mitomycin; Mitomycins; Phytohemagglutinins; Thymidine; Time Factors; Tuberculin; Uridine | 1986 |
Human monocyte-released cytotoxic factor: effect on various cellular functions, and dependency of cytolysis on various metabolic processes.
Topics: Adenosine Triphosphate; Cell Survival; Chloroquine; Colchicine; Cycloheximide; Cytotoxicity, Immunologic; Cytotoxins; Dactinomycin; Humans; Mitomycin; Mitomycins; Monocytes; Nucleic Acids; Protein Biosynthesis; Ricin; Uncoupling Agents | 1986 |
IFN-gamma facilitates NGF-induced neuronal differentiation in PC12 cells.
Topics: Adrenal Gland Neoplasms; Animals; Cell Differentiation; Cell Survival; Colchicine; Cytarabine; Hydroxyurea; Interferon-gamma; Mice; Mitomycin; Mitomycins; Nerve Growth Factors; Neurons; Pheochromocytoma; Rats; Recombinant Proteins; Tumor Cells, Cultured | 1988 |
Persistence of DNA lesions and the cytological cancellation of sister chromatid exchanges.
Topics: Antibiotics, Antineoplastic; Cells, Cultured; Chromosomes, Human; Colchicine; DNA; Humans; Lymphocytes; Mitomycin; Mitomycins; Sister Chromatid Exchange; Ultraviolet Rays | 1985 |
Physical and pharmacologic inhibition of the shedding of I-A antigens.
Topics: Animals; Colchicine; Detergents; Gene Expression Regulation; Glutaral; Histocompatibility Antigens Class II; Hot Temperature; Lymphocytes; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mitomycin; Mitomycins; Receptors, Antigen, B-Cell; Spleen; Ultraviolet Rays | 1984 |
A rapid screen for cumulative chromosomal damage in mice. Accumulation of circulating micronucleated erythrocytes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Nucleus; Colchicine; Cyclophosphamide; Erythrocytes; Evaluation Studies as Topic; Male; Mechlorethamine; Mice; Mitomycin; Mitomycins; Mutagenicity Tests; Triethylenemelamine | 1983 |
Effect of metabolic inhibitors on the ability of human T lymphocytes to form active T rosettes.
Topics: Animals; Colchicine; Cytochalasin B; Erythrocytes; Humans; Lectins; Mitomycin; Mitomycins; Rosette Formation; Sheep; T-Lymphocytes | 1984 |
[Stimulation of cell division by Ehrlich carcinoma cell surface antibodies].
Topics: Animals; Antibodies, Neoplasm; Carcinoma, Ehrlich Tumor; Cell Division; Cell Line; Cell Membrane; Cell Nucleus; Colchicine; Cycloheximide; Cytochalasin B; Dactinomycin; DNA, Neoplasm; Female; Immune Sera; Indomethacin; Interphase; Mice; Mitomycin; Mitomycins; Neoplasm Proteins; Rabbits; RNA, Neoplasm | 1984 |
An optimal, generalized sampling time of 30 +/- 6 h after double dosing in the mouse peripheral blood micronucleus test.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; Colchicine; Cyclophosphamide; Cytarabine; Floxuridine; Fluorouracil; Kinetics; Methotrexate; Mice; Mice, Inbred Strains; Micronucleus Tests; Mitomycin; Mutagens; Reticulocytes; Sulfuric Acid Esters; Time Factors | 1995 |
Isolation of micronuclei from mouse blood and fluorescence in situ hybridization with a mouse centromeric DNA probe.
Topics: Animals; Base Sequence; Cell Fractionation; Centromere; Colchicine; Cytarabine; DNA; DNA Probes; In Situ Hybridization, Fluorescence; Male; Mice; Micronucleus Tests; Mitomycin; Molecular Sequence Data; Vinblastine | 1994 |
Prominent inhibitory effects of tranilast on migration and proliferation of and collagen synthesis by vascular smooth muscle cells.
Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Cell Division; Cell Movement; Cells, Cultured; Colchicine; Collagen; Depression, Chemical; Dose-Response Relationship, Drug; Imidazoles; Male; Mitomycin; Muscle, Smooth, Vascular; Nifedipine; ortho-Aminobenzoates; Pancreatic Elastase; Phosphodiesterase Inhibitors; Pyridones; Rats; Rats, Inbred WKY | 1994 |
The cytochalasin-B micronucleus/kinetochore assay in vitro: studies with 10 suspected aneugens.
Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Cell Division; Cell Line; Centromere; Chloral Hydrate; Chlorides; Colchicine; Cricetinae; Cricetulus; Cytochalasin B; Diazepam; Dose-Response Relationship, Drug; Econazole; Humans; Hydroquinones; Micronucleus Tests; Mitomycin; Mutagens; Pyrimethamine; Thiabendazole; Thimerosal; Vinblastine | 1993 |
Cytokinesis-block micronucleus assay with kinetochore detection in colchicine-treated human fibroblasts.
Topics: Cell Division; Cell Line; Cell Nucleus; Colchicine; Cytochalasin B; Cytoplasm; Dose-Response Relationship, Drug; Fibroblasts; Humans; Male; Micronucleus Tests; Mitomycin; Mutagens; Skin; Spindle Apparatus | 1993 |
The effect of cytochalasin-B concentration on the frequency of micronuclei induced by four standard mutagens. Results from two laboratories.
Topics: Adult; Artifacts; Cells, Cultured; Colchicine; Cytochalasin B; Dose-Response Relationship, Drug; Drug Synergism; Ethyl Methanesulfonate; Humans; Lymphocytes; Male; Micronucleus Tests; Mitomycin; Mutagens; Vincristine | 1994 |
Flow cytometric detection of micronuclei induced by chemicals in poly- and normochromatic erythrocytes of mouse peripheral blood.
Topics: Acrylamide; Acrylamides; Animals; Benzimidazoles; Benzothiazoles; Bone Marrow; Colchicine; Erythrocytes; Flow Cytometry; Fluorescent Dyes; Male; Mice; Mice, Inbred C3H; Micronucleus Tests; Microscopy, Fluorescence; Mitomycin; Quinolines; Thiazoles | 1993 |
Indications for a threshold of chemically-induced aneuploidy in vitro in human lymphocytes.
Topics: Adult; Aneuploidy; Benzimidazoles; Carbamates; Cell Division; Cell Survival; Cells, Cultured; Centromere; Colchicine; Flow Cytometry; Humans; In Situ Hybridization, Fluorescence; Lymphocytes; Mebendazole; Methyl Methanesulfonate; Micronucleus Tests; Mitomycin; Mutagens; Nocodazole | 1995 |
Analysis by fluorescence in situ hybridization with a mouse gamma satellite DNA probe of isolated micronuclei induced in mice by two clastogens and two spindle poisons.
Topics: Animals; Centromere; Colchicine; Cytarabine; DNA Probes; DNA, Satellite; Dose-Response Relationship, Drug; Erythrocytes; In Situ Hybridization, Fluorescence; Male; Mice; Mice, Inbred Strains; Micronucleus Tests; Mitomycin; Mutagens; Spindle Apparatus; Vinblastine | 1995 |
The diplochromosome of endoreduplicated cells: a new approach to highlight the mechanism of sister chromatid exchange.
Topics: Animals; Bromodeoxyuridine; Cell Line; Chromosomes; Colchicine; Cricetinae; Cricetulus; Diploidy; Embryo, Mammalian; Lung; Metaphase; Mitomycin; Models, Genetic; Sister Chromatid Exchange | 1996 |
Cross-resistance to cis-diamminedichloroplatinum(II) of a multidrug-resistant lymphoma cell line associated with decreased drug accumulation and enhanced DNA repair.
Topics: Antineoplastic Agents; Aphidicolin; Cell Survival; Cisplatin; Colchicine; DNA Adducts; DNA Repair; DNA, Neoplasm; Doxorubicin; Drug Resistance, Neoplasm; Enzyme-Linked Immunosorbent Assay; Gene Expression; Genes, MDR; Humans; Lymphoma, Large B-Cell, Diffuse; Male; Mitomycin; Polymerase Chain Reaction; Puromycin; Spectrophotometry, Atomic; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Verapamil; Vincristine | 1996 |
Characterization of cigarette smoke-induced micronuclei in vitro.
Topics: Animals; Cells, Cultured; Colchicine; Cricetinae; Dose-Response Relationship, Drug; Fluorescent Antibody Technique, Indirect; Lung; Micronuclei, Chromosome-Defective; Mitomycin; Nicotiana; Plants, Toxic; Smoke | 1996 |
[Induction of micronuclei in erythrocytes of bone marrow and peripheral blood in laboratory mice following acute and subchronic exposure to DDT(fenarimol and nuarimol)].
Topics: Animals; Bone Marrow; Colchicine; Cyclophosphamide; Erythrocytes; Fungicides, Industrial; Male; Mice; Micronucleus Tests; Mitomycin; Mutagens; Pyrimidines | 1996 |
[Morphology and origin of micronuclei induced by mitotic inhibitors].
Topics: Animals; Centromere; Colchicine; Cyclophosphamide; Depression, Chemical; DNA; Male; Micronuclei, Chromosome-Defective; Mitomycin; Mitosis; Mutagens; Rats; Rats, Inbred Strains; Telomere; Vincristine | 1997 |
High body temperature induces micronuclei in mouse bone marrow.
Topics: Animals; Body Temperature; Bone Marrow; Cell Nucleus; Colchicine; Hot Temperature; Male; Mice; Mice, Inbred Strains; Micronucleus Tests; Mitomycin; Mutagens; Rectum; Time Factors | 1997 |
Simple detection of chemical mutagens by the alkaline single-cell gel electrophoresis (Comet) assay in multiple mouse organs (liver, lung, spleen, kidney, and bone marrow).
Topics: Alkylating Agents; Animals; Bone Marrow; Colchicine; Cross-Linking Reagents; Electrophoresis; Fluorouracil; Kidney; Liver; Lung; Male; Mice; Mice, Inbred Strains; Mitomycin; Mutagenicity Tests; Mutagens; Phenacetin; Polycyclic Aromatic Hydrocarbons; Spleen | 1997 |
Aneuploidy induction by benzo[a]pyrene and polyploidy induction by 7,12-dimethylbenz[a]anthracene in Chinese hamster cell lines V79-MZ and V79.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aneuploidy; Animals; Benzo(a)pyrene; Cell Cycle; Cell Line; CHO Cells; Chromosome Aberrations; Colchicine; Cricetinae; Cricetulus; Methylcholanthrene; Mitomycin; Mutagens; Polyploidy; Sister Chromatid Exchange | 1997 |
Spindle poisons can induce polyploidy by mitotic slippage and micronucleate mononucleates in the cytokinesis-block assay.
Topics: Benzimidazoles; Carbamates; Colchicine; Female; Humans; Leukocyte Count; Leukocytes, Mononuclear; Male; Mebendazole; Methyl Methanesulfonate; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mitomycin; Mutagens; Nocodazole; Polyploidy; Spindle Apparatus | 1998 |
Differential effects of aneugens and clastogens on incidences of multinucleated cells and of micronucleate cells in Chinese hamster lung (V79) cell line in vitro.
Topics: Aneuploidy; Animals; Cell Line; Cell Nucleus; Colchicine; Cricetinae; Cricetulus; Cyclophosphamide; Mitomycin; Mitotic Index; Mutagens; Vinblastine | 1998 |
Rapid method for improving slide quality in the bone marrow micronucleus assay; an adapted cellulose column procedure.
Topics: Animals; Bone Marrow Cells; Cellulose; Chromatography; Chromosome Breakage; Colchicine; Cyclophosphamide; Female; Male; Mice; Mice, Inbred Strains; Micronucleus Tests; Mitomycin; Mutagens; Vinblastine | 1999 |
The effect of hyperthermia on micronucleus induction by mutagens in mice.
Topics: Alkylating Agents; Animals; Antimetabolites; Cell Nucleus; Colchicine; Cross-Linking Reagents; Cyclophosphamide; Fever; Fluorouracil; Hyperthermia, Induced; Male; Mice; Mice, Inbred Strains; Micronucleus Tests; Mitomycin; Mutagens; Time Factors | 1999 |
Induction of micronuclei and other nuclear abnormalities in European minnow Phoxinus phoxinus and mollie Poecilia latipinna: an assessment of the fish micronucleus test.
Topics: Animals; Cadmium; Cell Nucleus; Colchicine; Cyclophosphamide; Cyprinidae; Dose-Response Relationship, Drug; Erythrocytes; Mercury; Metals, Heavy; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mitomycin; Mutagenicity Tests; Poecilia; Species Specificity | 2000 |
Multidrug resistance increment in a human colon carcinoma cell line by colchicine.
Topics: Adenocarcinoma; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Colchicine; Colonic Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Mitomycin; Tumor Cells, Cultured; Verapamil; Vinblastine; Vincristine | 2000 |
Chromosomal composition of micronuclei in mouse NIH 3T3 cells treated with acrylamide, extract of Tripterygium hypoglaucum (level) hutch, mitomycin C and colchicine, detected by multicolor FISH with centromeric and telomeric DNA probes.
Topics: 3T3 Cells; Acrylamide; Alkylating Agents; Animals; Antineoplastic Agents, Phytogenic; Centromere; Chromosomes; Colchicine; DNA Probes; Drugs, Chinese Herbal; In Situ Hybridization, Fluorescence; Mice; Micronuclei, Chromosome-Defective; Mitomycin; Mutagens; Telomere; Tripterygium | 2001 |
P-glycoprotein, glutathione and glutathione S-transferase increase in a colon carcinoma cell line by colchicine.
Topics: Adenocarcinoma; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Colchicine; Colonic Neoplasms; Drug Resistance, Multiple; Glutathione; Glutathione Transferase; Humans; Mitomycin; Tumor Cells, Cultured; Vinblastine; Vincristine | 2000 |
Shift in FTIR spectrum patterns in methomyl-exposed rat spleen cells.
Topics: Animals; Colchicine; Cross-Linking Reagents; Male; Methomyl; Mitomycin; Rats; Rats, Wistar; Spectroscopy, Fourier Transform Infrared; Spleen; Toxicity Tests | 2001 |
Micronuclei and other nuclear lesions as genotoxicity indicators in rainbow trout Oncorhynchus mykiss.
Topics: Acrylamide; Animals; Cell Nucleus; Colchicine; Cyclophosphamide; Erythrocytes; Injections, Intraperitoneal; Methyl Methanesulfonate; Methylnitrosourea; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mitomycin; Mutagens; Oncorhynchus mykiss | 2001 |
Etoposide and merbarone are clastogenic and aneugenic in the mouse bone marrow micronucleus test complemented by fluorescence in situ hybridization with the mouse minor satellite DNA probe.
Topics: Aneugens; Aneuploidy; Animals; Antibiotics, Antineoplastic; Bone Marrow; Chromosomes; Colchicine; DNA Probes; DNA, Satellite; Enzyme Inhibitors; Erythrocytes; Etoposide; Gout Suppressants; In Situ Hybridization, Fluorescence; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C3H; Micronucleus Tests; Mitomycin; Mutagens; Thiobarbiturates; Topoisomerase II Inhibitors | 2003 |
DRUGS OF CURRENT USE FOR THE TREATMENT OF CANCER AND ALLIED DISEASES.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antineoplastic Agents; Aziridines; Busulfan; Colchicine; Dactinomycin; Diethylstilbestrol; Estrogens; Fluorouracil; Gonadal Steroid Hormones; Mercaptopurine; Methotrexate; Mitomycin; Mitomycins; Neoplasms; Podophyllum; Progestins; Quinones; Thiotepa; Triethylenemelamine; Urethane; Vinblastine | 1963 |
[AN ATTEMPT TO ALTER THE RESISTANCE OF MICROORGANISMS WITH THE AID OF MUTAGENS].
Topics: Aminopterin; Animals; Antineoplastic Agents; Carboxylic Acids; Colchicine; Cyclopentanes; DNA; DNA, Bacterial; Drug Resistance; Drug Resistance, Microbial; Guinea Pigs; Isoniazid; Mitomycin; Mitomycins; Mutagens; Mutation; Mycobacterium tuberculosis; Research; RNA; RNA, Bacterial | 1963 |
THE INTRACELLULAR UNCOATING OF POXVIRUS DNA. II. THE MOLECULAR BASIS OF THE UNCOATING PROCESS.
Topics: Anti-Bacterial Agents; Arginine; Colchicine; Dactinomycin; Deoxyribonucleases; DNA; DNA, Viral; Mitomycin; Mitomycins; Nucleosides; Phenylalanine; Phosphorus Isotopes; Poxviridae; Proteins; Puromycin; Rabbits; Research; RNA; RNA, Viral; Ultraviolet Rays | 1964 |
Effect of cyanidin 3-O-beta-glucopyranoside on micronucleus induction in cultured human lymphocytes by four different mutagens.
Topics: Adult; Anthocyanins; Antioxidants; Apoptosis; Cells, Cultured; Colchicine; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Humans; Hydrogen Peroxide; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mitomycin; Mutagens; T-Lymphocytes | 2004 |
[Meso-inositol and cell division. II. Influence of meso-inositol on the mito-catalytic effect of colchicine].
Topics: Catalysis; Cell Division; Colchicine; Inositol; Leadership; Mitomycin | 1950 |
Practical threshold for micronucleated reticulocyte induction observed for low doses of mitomycin C, Ara-C and colchicine.
Topics: Acridine Orange; Animals; Colchicine; Cytarabine; Dose-Response Relationship, Drug; Flow Cytometry; Male; Mice; Micronucleus Tests; Mitomycin; Reticulocytes | 2006 |
SFTG international collaborative study on in vitro micronucleus test I. General conditions and overall conclusions of the study.
Topics: Aneugens; Animals; Bleomycin; Cell Line; CHO Cells; Clofibrate; Colchicine; Cricetinae; Cytarabine; Cytochalasin B; Diethylstilbestrol; Fluorouracil; Griseofulvin; Humans; In Vitro Techniques; International Cooperation; Leukemia L5178; Lymphocytes; Mannitol; Mice; Micronucleus Tests; Mitomycin; Mutagens; Thiabendazole | 2006 |
Cytotoxicity in cultured mammalian cells is a function of the method used to estimate it.
Topics: 2,4-Dinitrophenol; 4-Nitroquinoline-1-oxide; Animals; Benzimidazoles; Carbamates; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colchicine; Leukemia L5178; Mice; Micronucleus Tests; Mitomycin; Mitotic Index; Mutagenicity Tests; Mutagens; Trypan Blue | 2007 |
A comparative study on the anti-angiogenic effects of DNA-damaging and cytoskeletal-disrupting agents.
Topics: 2-Methoxyestradiol; Angiogenesis Inhibitors; Animals; Apoptosis; Bleomycin; Cattle; Cell Movement; Cell Proliferation; Colchicine; Cytoskeleton; DNA Damage; DNA Fragmentation; Endothelial Cells; Estradiol; Mitomycin; Neovascularization, Physiologic | 2009 |
Use of centromeric and telomeric DNA probes in in situ hybridization for differentiation of micronuclei induced by lomefloxacin.
Topics: Animals; Anti-Infective Agents; Centromere; Colchicine; DNA Probes; Fluoroquinolones; In Situ Hybridization; In Situ Hybridization, Fluorescence; Male; Mice; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mitomycin; Telomere | 2009 |
Etoposide; colchicine; mitomycin C and cyclophosphamide tested in the in vitro mammalian cell micronucleus test (MNvit) in Chinese hamster lung (CHL) cells at Covance laboratories; Harrogate UK in support of OECD draft Test Guideline 487.
Topics: Animals; Cell Count; Cell Death; Cell Line; Cell Proliferation; Colchicine; Cricetinae; Cricetulus; Cyclophosphamide; Cytochalasin B; Etoposide; Guidelines as Topic; Lung; Micronucleus Tests; Mitomycin; Mutagens | 2010 |
Mitomycin C, 5-fluoruracil, colchicine and etoposide tested in the in vitro mammalian cell micronucleus test (MNvit) in the human lymphoblastoid cell line TK6 at Novartis in support of OECD draft Test Guideline 487.
Topics: Cell Count; Cell Line; Cell Proliferation; Colchicine; Cytochalasin B; Cytokinesis; Etoposide; Fluorouracil; Guidelines as Topic; Humans; Lymphocytes; Micronucleus Tests; Mitomycin; Mutagens; Switzerland | 2010 |
Comparison of different cytotoxicity measures for the in vitro micronucleus test (MNVit) in L5178Y tk(+/-) cells: Summary of 4 compounds (Mitomycin C, Cyclophosphamide, Colchicine and Diethylstilboestrol) with clastogenic and aneugenic mode of action.
Topics: Aneugens; Animals; Cell Count; Cell Line, Tumor; Cell Proliferation; Colchicine; Cyclophosphamide; Diethylstilbestrol; Leukemia L5178; Mice; Micronucleus Tests; Mitomycin; Mutagens | 2010 |
Molecular cytogenetic evaluation of the aneugenic effects of teniposide in somatic and germinal cells of male mice.
Topics: Aneugens; Animals; Bromodeoxyuridine; Colchicine; Cytogenetic Analysis; DNA Probes; Erythrocytes; In Situ Hybridization, Fluorescence; Male; Mice; Micronucleus Tests; Mitomycin; Mitosis; Spermatozoa; Teniposide | 2012 |
Molecular cytogenetic evaluation of the mechanism of genotoxic potential of amsacrine and nocodazole in mouse bone marrow cells.
Topics: Amsacrine; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Bone Marrow Cells; Centromere; Colchicine; Cytogenetics; DNA Probes; Dose-Response Relationship, Drug; Erythrocytes; In Situ Hybridization; In Vitro Techniques; Male; Mice; Micronucleus Tests; Mitomycin; Mutagens; Nocodazole | 2013 |
Comet-FISH studies for evaluation of genetic damage of citalopram in somatic cells of the mouse.
Topics: Administration, Oral; Animals; Bone Marrow; Centromere; Citalopram; Colchicine; Comet Assay; Disease Models, Animal; DNA Damage; DNA Probes; Dose-Response Relationship, Drug; In Situ Hybridization, Fluorescence; Male; Mice; Micronucleus Tests; Mitomycin; Mutagens | 2013 |
New DNA probes to detect aneugenicity in rat bone marrow micronucleated cells by a pan-centromeric FISH analysis.
Topics: Aneugens; Animals; Antibiotics, Antineoplastic; Base Sequence; Bone Marrow; Centromere; Chromosomes; Colchicine; DNA Probes; DNA, Satellite; Erythrocytes; Flow Cytometry; In Situ Hybridization, Fluorescence; Male; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mitomycin; Molecular Sequence Data; Mutagens; Rats; Sequence Homology, Nucleic Acid; Tubulin Modulators; Vinblastine | 2013 |
Genotoxins induce binucleation in L5178Y and TK6 cells.
Topics: Animals; Cell Line; Colchicine; Cytarabine; Cytokinesis; DNA Damage; Humans; Methyl Methanesulfonate; Methylnitrosourea; Mice; Micronucleus Tests; Mitomycin; Mutagens | 2014 |
The effectiveness of colchicine combined with mitomycin C to prolong bleb function in trabeculectomy in rabbits.
Topics: Alkylating Agents; Animals; Blister; Colchicine; Drug Therapy, Combination; Eye Diseases; Male; Mitomycin; Neovascularization, Pathologic; Rabbits; Trabeculectomy; Tubulin Modulators | 2019 |