Page last updated: 2024-08-16

mitomycin and chitosan

mitomycin has been researched along with chitosan in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (11.43)18.2507
2000's15 (42.86)29.6817
2010's14 (40.00)24.3611
2020's2 (5.71)2.80

Authors

AuthorsStudies
Nagai, T; Onishi, H; Song, Y2
Kitano, M; Machida, Y; Nagai, T; Onishi, H; Sato, M1
Machida, Y; Nagai, T; Onishi, H; Sato, M; Takahara, J1
Kato, Y; Machida, Y; Onishi, H4
Choi, JJ; Hadwiger, LA; Klosterman, SJ1
Machida, Y; Onishi, H; Takahashi, H; Yoshiyasu, M1
Acar, A; Denkbaş, EB; Eroğlu, M; Irmak, S1
Denkbaş, EB; Eroğlu, M; Ozdemir, N; Oztürk, E1
Denkbaş, EB; Kurşaklioğlu, H; Misirli, Y; Oztürk, E1
Fang, R; Sun, D; Sun, J; Wan, G1
Dai, YQ; Du, YZ; Hu, FQ; Meng, P; Wei, XH; You, J; Yuan, H1
Fu, D; Gao, F; Jiang, G; Yu, B; Zhang, Y; Zhou, C1
Jiang, GB; Yin, QS; Zhang, Y; Zhou, CS1
Fu, D; Gao, F; Jiang, G; Zhang, Y; Zhou, C1
Aktaş, Y; Bilensoy, E; Doğan, AL; Esendağli, G; Mungan, NA; Sarisozen, C; Sen, M1
Aoki, H; Hanzawa, M; Hattori, H; Ishihara, M; Kishimoto, S; Kiyosawa, T; Murakami, K; Nakamura, S; Sato, Y; Takikawa, M; Tanaka, Y1
Bilensoy, E; Erdoğar, N; Mungan, A1
Ge, J; Li, X; Shao, T1
Han, B; Li, M; Liu, W1
Dai, S; Feng, X; Gu, J; Hu, H; Jiang, B; Lv, G; Sun, Y; Wang, D; Wang, J; Wang, Q; Yan, L; Yin, B; Yu, T1
Duan, L; Ge, J; Li, X; Quan, D; Zheng, Q1
Duan, L; Gao, Q; Ge, J; Li, X; Ma, J; Ouyang, L; Quan, D; Zheng, Q1
Bilensoy, E; Erdoğar, N; Iskit, AB; Mungan, NA1
Guan, J; Jin, Y; Shi, NQ; Zhang, XR; Zhao, Y; Zhu, HY1
Chen, M; Duan, L; Ge, J; Huang, L; Li, X; Ma, J; Quan, D; Xi, L; Zhang, W; Zhang, Z1
Bilensoy, E; Erdogar, N; Eroglu, H; İskit, AB; Mungan, NA; Sargon, MF1
Hou, Z; Huang, Y; Jia, M; Li, Y; Lin, J; Wu, H; Yang, X; Zhang, Q1
Alili, L; Brenneisen, P; Diekmann, J; Giesen, M; Holtkötter, O; Scholz, O1
Chao, JY; Chen, SN; Du, FG; Ma, HC; Meng, YZ; Ruan, WD; Wang, D; Wang, JZ; Zhu, YX1
Gong, M; Huang, Y; Shi, R; Tian, W; Wu, C; Zhang, J; Zhang, L1
Azizi, M; Bouzari, S; Fasihi-Ramandi, M; Sadeghi, Z1

Reviews

1 review(s) available for mitomycin and chitosan

ArticleYear
Application of chitin and chitosan derivatives in the pharmaceutical field.
    Current pharmaceutical biotechnology, 2003, Volume: 4, Issue:5

    Topics: Adjuvants, Pharmaceutic; Animals; Cell Survival; Chitin; Chitosan; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Mitomycin; Pharmaceutical Preparations; Sarcoma, Experimental; Tumor Cells, Cultured

2003

Other Studies

34 other study(ies) available for mitomycin and chitosan

ArticleYear
Synthesis and drug-release characteristics of the conjugates of mitomycin C with N-succinyl-chitosan and carboxymethyl-chitin.
    Chemical & pharmaceutical bulletin, 1992, Volume: 40, Issue:10

    Topics: Chitin; Chitosan; Delayed-Action Preparations; Drug Carriers; Mitomycin; Mitomycins

1992
Pharmacokinetic characteristics and antitumor activity of the N-succinyl-chitosan-mitomycin C conjugate and the carboxymethyl-chitin-mitomycin C conjugate.
    Biological & pharmaceutical bulletin, 1993, Volume: 16, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Division; Chitin; Chitosan; Chromatography, High Pressure Liquid; Drug Screening Assays, Antitumor; Female; Injections, Intraperitoneal; Leukemia L1210; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mitomycin; Mitomycins; Rats; Rats, Wistar; Tumor Cells, Cultured

1993
Preparation and drug release characteristics of the conjugates of mitomycin C with glycol-chitosan and N-succinyl-chitosan.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:2

    Topics: Antibiotics, Antineoplastic; Chitin; Chitosan; Hydrogen-Ion Concentration; Mitomycin

1996
In vivo drug release and antitumor characteristics of water-soluble conjugates of mitomycin C with glycol-chitosan and N-succinyl-chitosan.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:9

    Topics: Animals; Antibiotics, Antineoplastic; Biopolymers; Body Weight; Chemical Phenomena; Chemistry, Physical; Chitin; Chitosan; Chromatography, Gel; Delayed-Action Preparations; Glycols; Injections, Intraperitoneal; Injections, Intravenous; Leukemia P388; Male; Mice; Mice, Inbred Strains; Mitomycin; Mitomycins; Rats; Rats, Wistar; Sarcoma 180; Succinates; Tumor Cells, Cultured

1996
Biological fate of highly-succinylated N-succinyl-chitosan and antitumor characteristics of its water-soluble conjugate with mitomycin C at i.v. and i.p. administration into tumor-bearing mice.
    Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:12

    Topics: Animals; Antineoplastic Agents; Cell Division; Chitin; Chitosan; Drug Carriers; Injections, Intraperitoneal; Injections, Intravenous; Male; Mice; Mitomycin; Molecular Weight; Sarcoma 180; Solubility; Tissue Distribution

2000
A comparison of the effects of DNA-damaging agents and biotic elicitors on the induction of plant defense genes, nuclear distortion, and cell death.
    Plant physiology, 2001, Volume: 125, Issue:2

    Topics: Cell Death; Cell Nucleus; Chitin; Chitosan; Cisplatin; Dactinomycin; DNA Damage; Enhancer Elements, Genetic; Microscopy, Fluorescence; Mitomycin; Nicotiana; Pisum sativum; Plants, Genetically Modified; Promoter Regions, Genetic; RNA, Plant

2001
Lactosaminated and intact N-succinyl-chitosans as drug carriers in liver metastasis.
    International journal of pharmaceutics, 2001, Sep-11, Volume: 226, Issue:1-2

    Topics: Animals; Area Under Curve; Chitin; Chitosan; Drug Carriers; Injections, Intravenous; Lactose; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Mitomycin; Neoplasm Metastasis; Tissue Distribution

2001
Preparation and in vitro properties of N-succinylchitosan- or carboxymethylchitin-mitomycin C conjugate microparticles with specified size.
    Drug development and industrial pharmacy, 2001, Volume: 27, Issue:7

    Topics: Antibiotics, Antineoplastic; Chemical Phenomena; Chemistry, Physical; Chitin; Chitosan; Chromatography, High Pressure Liquid; Emulsions; Excipients; Liver; Mitomycin; Molecular Weight; Particle Size

2001
Design and evaluation of a mucoadhesive therapeutic agent delivery system for postoperative chemotherapy in superficial bladder cancer.
    International journal of pharmaceutics, 2002, Mar-20, Volume: 235, Issue:1-2

    Topics: Adhesives; Animals; Antibiotics, Antineoplastic; Biocompatible Materials; Chitin; Chitosan; Drug Carriers; Drug Delivery Systems; Drug Evaluation, Preclinical; Microscopy, Electron, Scanning; Mitomycin; Postoperative Care; Sheep; Urinary Bladder Neoplasms

2002
Efficacy of lactosaminated and intact N-succinylchitosan-mitomycin C conjugates against M5076 liver metastatic cancer.
    The Journal of pharmacy and pharmacology, 2002, Volume: 54, Issue:4

    Topics: Amino Sugars; Animals; Area Under Curve; Chitin; Chitosan; Drug Administration Schedule; Fluorescein-5-isothiocyanate; Humans; Injections, Intravenous; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Mitomycin; Neoplasm Metastasis; Tissue Distribution; Treatment Outcome; Tumor Cells, Cultured

2002
Bioadhesive drug carriers for postoperative chemotherapy in bladder cancer.
    Advances in experimental medicine and biology, 2004, Volume: 553

    Topics: Administration, Intravesical; Alginates; Animals; Antibiotics, Antineoplastic; Chitosan; Cross-Linking Reagents; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Drug Therapy; Humans; In Vitro Techniques; Materials Testing; Mitomycin; Rabbits; Tissue Adhesions; Urinary Bladder; Urinary Bladder Neoplasms

2004
Preparation and characterization of Mitomycin-C loaded chitosan-coated alginate microspheres for chemoembolization.
    Journal of microencapsulation, 2005, Volume: 22, Issue:2

    Topics: Alginates; Antibiotics, Antineoplastic; Biocompatible Materials; Calcium Chloride; Chemoembolization, Therapeutic; Chitosan; Cross-Linking Reagents; Delayed-Action Preparations; Drug Compounding; Humans; Microscopy, Electron, Scanning; Microspheres; Mitomycin; Molecular Weight; Neoplasms; Particle Size; Surface Properties

2005
Comparison between mitomycin C and chitosan for prevention of anterior glottic steno after CO2 laser cordectomy in dogs.
    The Laryngoscope, 2007, Volume: 117, Issue:11

    Topics: Alkylating Agents; Analysis of Variance; Animals; Carbon Dioxide; Chitosan; Dogs; Glottis; Laryngostenosis; Laser Therapy; Mitomycin; Prospective Studies; Statistics, Nonparametric; Vocal Cords

2007
PEGylated chitosan-based polymer micelle as an intracellular delivery carrier for anti-tumor targeting therapy.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2008, Volume: 70, Issue:3

    Topics: Animals; Antibiotics, Antineoplastic; Cell Line; Cell Proliferation; Chemistry, Pharmaceutical; Chitosan; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Humans; Inhibitory Concentration 50; Liver; Macrophages; Mice; Micelles; Mitomycin; Particle Size; Polyethylene Glycols; Rats; Solubility; Stearic Acids; Time Factors

2008
[Development of chitosan/polyethylene glycols-succinate mitomycin C film drug delivery system and releasing character in vitro].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2008, Volume: 22, Issue:5

    Topics: Chitosan; Drug Delivery Systems; In Vitro Techniques; Mitomycin; Polyethylene Glycols

2008
[In vitro drug release from a mitomycin C delivery system and its effect against scar tissue adhesion in vivo].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2008, Volume: 28, Issue:9

    Topics: Animals; Chitosan; Drug Delivery Systems; Intervertebral Disc; Mitomycin; Polyethylene Glycols; Polyethylenes; Rats; Rats, Sprague-Dawley; Succinates; Tissue Adhesions

2008
[Therapeutic effects of chitosan/polyethylene glycols-succinate/mitomycin C film drug delivery system on epidural scarring tissues after laminectomy of SD rats].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2008, Volume: 22, Issue:10

    Topics: Animals; Biocompatible Materials; Chitosan; Cicatrix; Disease Models, Animal; Drug Delivery Systems; Epidural Space; Laminectomy; Male; Mitomycin; Polyethylenes; Postoperative Complications; Rats; Rats, Sprague-Dawley; Succinates

2008
Intravesical cationic nanoparticles of chitosan and polycaprolactone for the delivery of Mitomycin C to bladder tumors.
    International journal of pharmaceutics, 2009, Apr-17, Volume: 371, Issue:1-2

    Topics: Administration, Intravesical; Animals; Antibiotics, Antineoplastic; Cations; Cell Survival; Chitosan; Delayed-Action Preparations; Drug Carriers; Drug Compounding; HeLa Cells; Humans; Mice; Microscopy, Electron, Scanning; Mitomycin; Nanoparticles; Particle Size; Polyesters; Surface Properties; Urinary Bladder Neoplasms

2009
Hydrogel blends of chitin/chitosan, fucoidan and alginate as healing-impaired wound dressings.
    Biomaterials, 2010, Volume: 31, Issue:1

    Topics: Alginates; Animals; Bandages; Cells, Cultured; Chitin; Chitosan; Glucuronic Acid; Hexuronic Acids; Hydrogels; Mitomycin; Polysaccharides; Rats; Wound Healing

2010
Preparation and characterization of cationic nanoparticles loaded with Mitomycin C by double emulsion and ionotropic gelation techniques.
    Journal of controlled release : official journal of the Controlled Release Society, 2010, Nov-20, Volume: 148, Issue:1

    Topics: Cations; Chitosan; Drug Delivery Systems; Emulsions; Gelatin; Gels; Hydrogen-Ion Concentration; Mitomycin; Nanoparticles; Particle Size; Technology, Pharmaceutical

2010
Target drug delivery system as a new scarring modulation after glaucoma filtration surgery.
    Diagnostic pathology, 2011, Jul-08, Volume: 6

    Topics: Chitosan; Cicatrix; Drug Carriers; Drug Delivery Systems; Fibrinolytic Agents; Fibrosis; Filtering Surgery; Humans; Hyaluronic Acid; Mitomycin; Nanoparticles; Postoperative Complications; Receptors, LDL; Wound Healing

2011
Preparation and properties of a drug release membrane of mitomycin C with N-succinyl-hydroxyethyl chitosan.
    Journal of materials science. Materials in medicine, 2011, Volume: 22, Issue:12

    Topics: Animals; Biocompatible Materials; Cell Line; Chitosan; Drug Delivery Systems; Drug Liberation; Female; Fibroblasts; Magnetic Resonance Spectroscopy; Membranes, Artificial; Mice; Mitomycin; Permeability; Rabbits; Rats; Rats, Wistar; Spectroscopy, Fourier Transform Infrared; Water

2011
A comparative study of the preventive effects of mitomycin C and chitosan on intraarticular adhesion after knee surgery in rabbits.
    Cell biochemistry and biophysics, 2012, Volume: 62, Issue:1

    Topics: Alkylating Agents; Animals; Chitosan; Cicatrix; Disease Models, Animal; Fibroblasts; Hydroxyproline; Knee Joint; Male; Mitomycin; Rabbits; Tissue Adhesions

2012
Synthesis and controlled release of mitomycin C from a chitosan-based polymeric prodrug.
    Journal of controlled release : official journal of the Controlled Release Society, 2011, Nov-30, Volume: 152 Suppl 1

    Topics: Cell Survival; Cells, Cultured; Chemistry, Pharmaceutical; Chitosan; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Fibroblasts; Humans; Kinetics; Magnetic Resonance Spectroscopy; Mitomycin; Oxidation-Reduction; Periodic Acid; Prodrugs; Solubility; Technology, Pharmaceutical

2011
Synthesis of a novel CS-g-MMCs conjugate and the inhabitation on the proliferation of Tenon's capsule fibroblasts in vitro.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2012, Aug-15, Volume: 46, Issue:5

    Topics: Actins; Adolescent; Adult; Antimetabolites; Apoptosis; Cell Movement; Cell Proliferation; Cells, Cultured; Chemistry, Pharmaceutical; Chitosan; Chromatography, Gel; Delayed-Action Preparations; DNA Replication; Dose-Response Relationship, Drug; Drug Carriers; Female; Fibroblasts; Gene Expression Regulation; Humans; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Male; Middle Aged; Mitomycin; Muramidase; Solubility; Spectroscopy, Fourier Transform Infrared; Technology, Pharmaceutical; Tenon Capsule; Young Adult

2012
Prolonged retention and in vivo evaluation of cationic nanoparticles loaded with Mitomycin C designed for intravesical chemotherapy of bladder tumours.
    Journal of microencapsulation, 2012, Volume: 29, Issue:6

    Topics: Animals; Antibiotics, Antineoplastic; Chitosan; Drug Delivery Systems; Drug Screening Assays, Antitumor; Humans; Male; Mitomycin; Nanoparticles; Polyesters; Polylysine; Rats; Rats, Sprague-Dawley; Urinary Bladder Neoplasms

2012
Deoxycholic acid-grafted PEGylated chitosan micelles for the delivery of mitomycin C.
    Drug development and industrial pharmacy, 2015, Volume: 41, Issue:6

    Topics: Animals; Antibiotics, Antineoplastic; Area Under Curve; Biological Availability; Chemistry, Pharmaceutical; Chitosan; Deoxycholic Acid; Drug Carriers; Drug Compounding; Drug Delivery Systems; Magnetic Resonance Spectroscopy; Male; Micelles; Mitomycin; Particle Size; Polyethylene Glycols; Rats; Rats, Wistar; Spectroscopy, Fourier Transform Infrared; Tissue Distribution

2015
CSM enhances the filtration bleb survival in rabbit model of experimental glaucoma surgery.
    Current eye research, 2014, Volume: 39, Issue:10

    Topics: Alkylating Agents; Animals; Chitosan; Conjunctiva; Disease Models, Animal; Drug Carriers; Fibrosis; Glaucoma; Injections, Intraocular; Intraocular Pressure; Mitomycin; Postoperative Complications; Rabbits; Trabeculectomy; Wound Healing

2014
Cationic core-shell nanoparticles for intravesical chemotherapy in tumor-induced rat model: safety and efficacy.
    International journal of pharmaceutics, 2014, Aug-25, Volume: 471, Issue:1-2

    Topics: Administration, Intravesical; Animals; Antibiotics, Antineoplastic; Butylhydroxybutylnitrosamine; Cations; Chitosan; Disease-Free Survival; Drug Carriers; Kaplan-Meier Estimate; Male; Mitomycin; Nanoparticles; Polyesters; Rats, Sprague-Dawley; Urinary Bladder; Urinary Bladder Neoplasms

2014
Development of both methotrexate and mitomycin C loaded PEGylated chitosan nanoparticles for targeted drug codelivery and synergistic anticancer effect.
    ACS applied materials & interfaces, 2014, Jul-23, Volume: 6, Issue:14

    Topics: Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Chitosan; Drug Delivery Systems; Drug Synergism; HeLa Cells; Humans; Methotrexate; Mice; Mitomycin; Nanoparticles; Neoplasms, Experimental; Polyethylene Glycols

2014
A three-dimensional skin equivalent reflecting some aspects of in vivo aged skin.
    Experimental dermatology, 2016, Volume: 25, Issue:1

    Topics: Adult; Aged; Cells, Cultured; Cellular Senescence; Child; Chitosan; Coculture Techniques; Collagen; Elastin; Epidermis; Female; Fibroblasts; Filaggrin Proteins; Glycosaminoglycans; Humans; Intermediate Filament Proteins; Keratinocytes; Male; Mitomycin; Skin; Skin Aging; Tissue Engineering; Tissue Scaffolds

2016
Developing multi-cellular tumor spheroid model (MCTS) in the chitosan/collagen/alginate (CCA) fibrous scaffold for anticancer drug screening.
    Materials science & engineering. C, Materials for biological applications, 2016, Volume: 62

    Topics: Alginates; Antineoplastic Agents; Azacitidine; Cell Culture Techniques; Cell Proliferation; Cell Survival; Chitosan; Coculture Techniques; Doxorubicin; Drug Screening Assays, Antitumor; Epithelial-Mesenchymal Transition; Glucuronic Acid; Hexuronic Acids; Humans; MCF-7 Cells; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Mitomycin; Spectroscopy, Fourier Transform Infrared; Spheroids, Cellular; X-Ray Diffraction

2016
Effective delivery of mitomycin-C and meloxicam by double-layer electrospun membranes for the prevention of epidural adhesions.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2020, Volume: 108, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Cell Proliferation; Chitosan; Drug Carriers; Drug Liberation; Drug Therapy, Combination; Epidural Space; Fibroblasts; Humans; Laminectomy; Male; Meloxicam; Membranes, Artificial; Mitomycin; Models, Animal; Nanofibers; Polyesters; Rabbits; Tissue Adhesions

2020
Mannosylated chitosan nanoparticles loaded with FliC antigen as a novel vaccine candidate against Brucella melitensis and Brucella abortus infection.
    Journal of biotechnology, 2020, Feb-20, Volume: 310

    Topics: Animals; Antigens, Bacterial; Antineoplastic Combined Chemotherapy Protocols; Brucella abortus; Brucella melitensis; Brucella Vaccine; Brucellosis; Chitosan; Cisplatin; Female; Ifosfamide; Mannose; Mice, Inbred BALB C; Mitomycin; Nanoparticles

2020