Page last updated: 2024-08-16

mitomycin and caffeine

mitomycin has been researched along with caffeine in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199018 (47.37)18.7374
1990's9 (23.68)18.2507
2000's7 (18.42)29.6817
2010's4 (10.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Balansky, RM; Blagoeva, PM; Mircheva, TJ1
Kim, J; Levin, RE3
Agostoni Carbone, ML; Melchioretto, P; Primignani, P; Sora, S1
Matsuda, Y; Seki, N; Tobari, I; Utsugi-Takeuchi, T1
Hromic, A; Kirby, R1
Cortés, F; Mateos, S; Ortiz, T; Piñero, J1
Andriadze, MI; Mikhel'son, VM; Pleskach, NM; Zhestianikov, VD1
Sasaki, MS; Wakata, A1
MacPhee, DG1
Ceccherini, I; Loprieno, N; Sbrana, I1
McKelvey, VJ; McKenna, PG1
Abratt, VR; Jones, DT; Woods, DR1
Dozi-Vassiliades, J; Granitsas, A; Mourelatos, D; Tsigalidou-Balla, V1
Fujii, T; Nakatsuka, T1
Fujii, T; Hanada, S; Nakatsuka, T1
De Salvia, R; Degrassi, F; Fiore, M; Palitti, F; Tanzarella, C2
Ishii, Y; Watatani, M1
Kozuka, H; Miyahara, T; Sakaguchi, M; Yamada, H1
Dubinina, LG1
Wenger, SL1
Arwert, F; Dijkmans, LM; Joenje, H; Kruyt, FA1
Bagby, GC; Bakke, AC; Brown, MG; Grompe, M; Heinrich, MC; Hoatlin, ME; Keeble, WW; Magenis, RE; Olson, SB; Reifsteck, CA; Silvey, KV; Zhi, Y; Zigler, AJ1
Johnstone, P; Kohler, S; Moses, RE; Olson, S; Reifsteck, C; Worland, P1
Franchitto, A; Mosesso, P; Palitti, F; Pichierri, P1
Dolnikov, A; Millington, M; Sun, LQ; Symonds, G1
Jiang, T; Kline, R; Rybin, VO; Steinberg, SF; Xu, X1
Akkari, Y; Christian, JL; Cimprich, KA; Costanzo, V; de Graaf, B; de Winter, J; Gautier, J; Hoatlin, ME; Joenje, H; Lupardus, PJ; Olson, S; Reuter, T; Sobeck, A; Stone, S; Wallisch, M; Wang, W1
Kalaitzis, C; Lialiaris, T; Papachristou, F; Simopoulos, C; Sofikitis, N; Touloupidis, S1
Anachkova, B; Mladenov, E; Tsaneva, I1
Lialiaris, T; Papachristou, F; Simopoulou, M; Sofikitis, N; Touloupidis, S; Tsalikidis, C1
Lialiaris, TS; Mourelatos, C; Papachristou, F; Simopoulou, M1
Bolay, C; Eckhardt, A; Hiller, KA; Krifka, S; Müller, P; Schmalz, G; Schweikl, H; Spagnuolo, G1

Reviews

1 review(s) available for mitomycin and caffeine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

37 other study(ies) available for mitomycin and caffeine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Potentiation by caffeine of the frequencies of micronuclei induced by mitomycin C and cyclophosphamide in young mice.
    Mutation research, 1991, Volume: 246, Issue:1

    Topics: Alkylating Agents; Animals; Caffeine; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Synergism; Erythrocytes; Female; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mitomycin; Mitomycins; Pregnancy

1991
Influence of caffeine on the induction of SOS functions recA and umuC by mitomycin C in Escherichia coli.
    Microbios, 1990, Volume: 64, Issue:260-261

    Topics: Alkylating Agents; Caffeine; Escherichia coli; Gene Expression Regulation, Bacterial; Mitomycin; Mitomycins; SOS Response, Genetics

1990
Caffeine interactions with methyl methanesulphonate, hycanthone, benlate, and cadmium chloride in chromosomal meiotic segregation of Saccharomyces cerevisiae.
    Mutation research, 1988, Volume: 201, Issue:1

    Topics: Benomyl; Bleomycin; Cadmium; Cadmium Chloride; Caffeine; Chromosomes; Diploidy; Distamycins; Drug Interactions; Drug Synergism; Hycanthone; Meiosis; Methyl Methanesulfonate; Mitomycin; Mitomycins; Saccharomyces cerevisiae

1988
X-ray- and mitomycin C (MMC)-induced chromosome aberrations in spermiogenic germ cells and the repair capacity of mouse eggs for the X-ray and MMC damage.
    Mutation research, 1989, Volume: 211, Issue:1

    Topics: Animals; Caffeine; Chromatids; Chromosome Aberrations; DNA Damage; DNA Repair; Female; Male; Mice; Mice, Inbred Strains; Mitomycin; Mitomycins; Sister Chromatid Exchange; Spermatogenesis; X-Rays; Zygote

1989
Isolation and study of two mutants of Streptomyces cattleya affected in DNA repair and genetic instability.
    FEMS microbiology letters, 1989, Jan-15, Volume: 48, Issue:2

    Topics: Arsenic; Arsenites; Caffeine; DNA Repair; Genes, Bacterial; Mitomycin; Mitomycins; Mutation; Spores, Bacterial; Streptococcus; Ultraviolet Rays

1989
G2 effects of DNA-repair inhibitors on chromatid-type aberrations in root-tip cells treated with maleic hydrazide and mitomycin C.
    Mutation research, 1989, Volume: 226, Issue:2

    Topics: Caffeine; Cell Cycle; Chromosome Aberrations; Chromosomes; Cytarabine; DNA Damage; DNA Repair; Floxuridine; Hydroxyurea; In Vitro Techniques; Interphase; Maleic Hydrazide; Mitomycin; Mitomycins; Plants; Pyridazines; Thymidine

1989
[Spontaneous and induced sister chromatid exchanges in the blood lymphocytes of healthy persons and of xeroderma pigmentosum patients exposed to the inhibitors of DNA repair and replication caffeine, 3-methoxybenzamide and novobiocin].
    Tsitologiia, 1986, Volume: 28, Issue:1

    Topics: Adult; Benzamides; Caffeine; Cells, Cultured; DNA Repair; DNA Replication; Ethyl Methanesulfonate; Humans; Lymphocyte Activation; Lymphocytes; Middle Aged; Mitomycin; Mitomycins; Novobiocin; Phytohemagglutinins; Sister Chromatid Exchange; Ultraviolet Rays; Xeroderma Pigmentosum

1986
Influence of caffeine on mitomycin C induced mutagenesis.
    Microbios, 1986, Volume: 46, Issue:186

    Topics: Caffeine; Cell Division; DNA Repair; Mitomycin; Mitomycins; Mutation; Salmonella typhimurium

1986
Measurement of micronuclei by cytokinesis-block method in cultured Chinese hamster cells: comparison with types and rates of chromosome aberrations.
    Mutation research, 1987, Volume: 190, Issue:1

    Topics: Animals; Caffeine; Cell Division; Cell Line; Cell Nucleus; Chromosome Aberrations; Cricetinae; Cricetulus; Cytochalasin B; Demecolcine; Mitomycin; Mitomycins; Mutagenicity Tests

1987
Influence of caffeine on mitomycin C induced mutagenesis: a simple explanation.
    Microbios, 1987, Volume: 50, Issue:203

    Topics: Caffeine; Mitomycin; Mitomycins; Mutagenicity Tests; Mutagens; Mutation; Salmonella typhimurium

1987
Caffeine post-treatment causes a shift in the chromosome aberration types induced by mitomycin C, suggesting a caffeine-sensitive mechanism of DNA repair in G2.
    Mutagenesis, 1988, Volume: 3, Issue:1

    Topics: Caffeine; Cells, Cultured; Chromosome Aberrations; DNA Repair; Humans; Interphase; Lymphocytes; Mitomycin; Mitomycins

1988
Mechanism of caffeine repression of mitomycin C induced reversion in Salmonella typhimurium strain TA94.
    Microbios, 1988, Volume: 53, Issue:216-217

    Topics: Caffeine; Kinetics; Mitomycin; Mitomycins; Mutagenicity Tests; Mutation; Salmonella typhimurium

1988
Enhanced synergism between caffeine and mitomycin C in the induction of cytogenetic aberrations in thymidine kinase-deficient Friend murine erythroleukaemia cells.
    Mutagenesis, 1986, Volume: 1, Issue:3

    Topics: Animals; Caffeine; Cell Line; Chromosome Aberrations; Dose-Response Relationship, Drug; Drug Synergism; Friend murine leukemia virus; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Mice; Mitomycin; Mitomycins; Mutagens; Thymidine Kinase

1986
Isolation and physiological characterization of mitomycin C-sensitive/UV-sensitive mutants in Bacteroides fragilis.
    Journal of general microbiology, 1985, Volume: 131, Issue:9

    Topics: Bacteriophages; Bacteroides fragilis; Caffeine; Drug Resistance, Microbial; Mitomycin; Mitomycins; Mutation; Ultraviolet Rays; Virus Activation

1985
Enhancement by methylxanthines of sister-chromatid exchange frequency induced by cytostatics in normal and leukemic human lymphocytes.
    Mutation research, 1983, Volume: 121, Issue:2

    Topics: Caffeine; Cells, Cultured; Crossing Over, Genetic; Cytarabine; Drug Synergism; Humans; Leukemia; Lymphocytes; Mitomycin; Mitomycins; Mutagenicity Tests; Mutagens; Sister Chromatid Exchange; Xanthines

1983
Potentiating effects of caffeine on teratogenicity of alkylating agents in mice.
    Teratology, 1983, Volume: 28, Issue:1

    Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Alkylating Agents; Animals; Antibiotics, Antineoplastic; Caffeine; Chlorambucil; Cyclophosphamide; Drug Synergism; Embryo Implantation; Female; Fetal Resorption; Methylnitronitrosoguanidine; Mice; Mice, Inbred Strains; Mitomycin; Mitomycins; Pregnancy; Teratogens; Thiotepa

1983
Potentiating effects of methylxanthines on teratogenicity of mitomycin C in mice.
    Teratology, 1983, Volume: 28, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Antibiotics, Antineoplastic; Caffeine; Drug Synergism; Female; Mice; Mice, Inbred ICR; Mitomycin; Mitomycins; Pregnancy; Structure-Activity Relationship; Theobromine; Theophylline; Xanthines

1983
Enhancement of induced sister chromatid exchange and chromosomal aberrations by inhibitors of DNA repair processes.
    Toxicologic pathology, 1984, Volume: 12, Issue:3

    Topics: Animals; Aphidicolin; Caffeine; Chromosome Aberrations; Cricetinae; Cricetulus; Diterpenes; DNA; DNA Repair; Female; Humans; Hydroxyurea; Mitomycin; Mitomycins; Sister Chromatid Exchange

1984
Cell-stage dependence of the formation of SCEs and chromosomal aberrations.
    Basic life sciences, 1984, Volume: 29 Pt A

    Topics: Caffeine; Cell Cycle; Cells, Cultured; Chromosome Aberrations; DNA Replication; Humans; Interphase; Lymphocytes; Mitomycin; Mitomycins; Models, Genetic; Sister Chromatid Exchange

1984
Potentiation of induced sister chromatid exchanges and chromatid-type aberrations by inhibitors of DNA synthesis and repair in G2.
    Basic life sciences, 1984, Volume: 29 Pt A

    Topics: Aphidicolin; Caffeine; Cells, Cultured; Chromosome Aberrations; Diterpenes; DNA Repair; DNA Replication; Humans; Hydroxyurea; Interphase; Lymphocytes; Mitomycin; Mitomycins; Sister Chromatid Exchange

1984
Antagonizing effect of triphenyltin chloride on cytosine-1-beta-D-arabinofuranoside potentiation of chromosome aberrations induced by mitomycin C.
    Mutation research, 1994, Volume: 323, Issue:3

    Topics: Animals; Caffeine; CHO Cells; Chromosome Aberrations; Cricetinae; Cytarabine; Drug Antagonism; Drug Synergism; G2 Phase; Hydroxyurea; Mitomycin; Mutagenesis; Organotin Compounds

1994
[The effect of inhibitors on induced mutagenesis].
    Genetika, 1993, Volume: 29, Issue:8

    Topics: Aphidicolin; Caffeine; Cell Line; Cytarabine; DNA Replication; G1 Phase; G2 Phase; Hydroxyurea; Mitomycin; Mutagenesis; Seeds

1993
Chemical induction of sister chromatid exchange at fragile sites.
    Cancer genetics and cytogenetics, 1995, Volume: 85, Issue:1

    Topics: Aphidicolin; Caffeine; Cells, Cultured; Chromosome Fragile Sites; Chromosome Fragility; Floxuridine; Humans; Lymphocytes; Mitomycin; Sister Chromatid Exchange

1995
Involvement of the Fanconi's anemia protein FAC in a pathway that signals to the cyclin B/cdc2 kinase.
    Cancer research, 1997, Jun-01, Volume: 57, Issue:11

    Topics: Apoptosis; Caffeine; Cell Cycle; Cells, Cultured; Cyclin-Dependent Kinases; Cyclins; Fanconi Anemia; Fanconi Anemia Complementation Group C Protein; G2 Phase; Humans; Mitomycin; Mitosis; Nucleic Acid Synthesis Inhibitors; Phosphodiesterase Inhibitors; Phosphorylation; Proteins; S Phase; Signal Transduction; Tyrosine

1997
DNA cross-linker-induced G2/M arrest in group C Fanconi anemia lymphoblasts reflects normal checkpoint function.
    Blood, 1998, Jan-01, Volume: 91, Issue:1

    Topics: Caffeine; Cell Line, Transformed; Cross-Linking Reagents; DNA; DNA Damage; DNA, Complementary; Fanconi Anemia; G2 Phase; Humans; Hydroxyurea; Lymphocytes; Metaphase; Mitomycin; Transfection

1998
Fanconi anemia group A and D cell lines respond normally to inhibitors of cell cycle regulation.
    Somatic cell and molecular genetics, 1997, Volume: 23, Issue:6

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Caffeine; Cell Cycle; Cells, Cultured; Central Nervous System Stimulants; Chromosome Breakage; Cross-Linking Reagents; DNA Adducts; Enzyme Inhibitors; Fanconi Anemia; Humans; Hydrogen Peroxide; Hydroxyurea; Methyl Methanesulfonate; Mitomycin; Oxidants

1997
Caffeine effect on the mitotic delay induced by G2 treatment with UVC or mitomycin C.
    Mutagenesis, 1998, Volume: 13, Issue:5

    Topics: Animals; Caffeine; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; DNA Damage; DNA Repair; Fibroblasts; G2 Phase; Mitomycin; Mitosis; S Phase; Ultraviolet Rays

1998
Induced p21WAF1 expression acts to reverse myc myelomonocytic cell transformation.
    Cancer gene therapy, 2000, Volume: 7, Issue:11

    Topics: Animals; Apoptosis; Blotting, Northern; Caffeine; Carcinogens; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Flow Cytometry; G1 Phase; G2 Phase; Immunohistochemistry; In Situ Nick-End Labeling; Interleukin-3; Macrophage Colony-Stimulating Factor; Mice; Mitomycin; Monocytes; Nucleic Acid Synthesis Inhibitors; Oncogene Protein p55(v-myc); Phenotype; Plasmids; Polymerase Chain Reaction; Proto-Oncogene Proteins c-myc; Retroviridae; RNA, Catalytic; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tumor Suppressor Protein p53

2000
Abnormal calcium and protein kinase C-epsilon signaling in hypertrophied atrial tumor myocytes (AT-1 cells).
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:6

    Topics: Animals; Caffeine; Calcium Signaling; Calcium-Transporting ATPases; Cardiomegaly; Cell Differentiation; Cell Division; Cell Size; Endothelins; Female; Heart Atria; Heart Neoplasms; Isoenzymes; Mice; Mitomycin; Models, Cardiovascular; Myocardium; Nucleic Acid Synthesis Inhibitors; Protein Kinase C; Protein Kinase C-epsilon; Protein Transport; RNA, Messenger; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Signal Transduction; Tumor Cells, Cultured

2001
Fanconi anemia proteins are required to prevent accumulation of replication-associated DNA double-strand breaks.
    Molecular and cellular biology, 2006, Volume: 26, Issue:2

    Topics: Amino Acid Sequence; Animals; Ataxia Telangiectasia Mutated Proteins; Caffeine; Carrier Proteins; Cell Cycle Proteins; Chromatin; Cross-Linking Reagents; DNA Damage; DNA Repair; DNA Replication; Fanconi Anemia Complementation Group A Protein; Fanconi Anemia Complementation Group D2 Protein; Fanconi Anemia Complementation Group Proteins; Female; In Vitro Techniques; Mitomycin; Molecular Sequence Data; Oocytes; Protein Serine-Threonine Kinases; S Phase; Sequence Homology, Amino Acid; Xenopus laevis; Xenopus Proteins

2006
Evidence of increased chromosomal instability in infertile males after exposure to mitomycin C and caffeine.
    Asian journal of andrology, 2006, Volume: 8, Issue:2

    Topics: Adult; Caffeine; Chromosome Aberrations; DNA Repair; Humans; Infertility, Male; Lymphocytes; Male; Middle Aged; Mitomycin; Mitotic Index; Sister Chromatid Exchange

2006
Activation of the S phase DNA damage checkpoint by mitomycin C.
    Journal of cellular physiology, 2007, Volume: 211, Issue:2

    Topics: Androstadienes; Antibiotics, Antineoplastic; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Caffeine; Cell Cycle Proteins; Cell Nucleus; Chromatin; Cross-Linking Reagents; DNA Damage; DNA Replication; DNA-Binding Proteins; HeLa Cells; Histones; Humans; Mitomycin; Nuclear Matrix; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Rad51 Recombinase; Recombination, Genetic; S Phase; Time Factors; Tumor Suppressor Proteins; Wortmannin

2007
DNA damage and chromosomal aberrations in various types of male factor infertility.
    Fertility and sterility, 2008, Volume: 90, Issue:5

    Topics: Adult; Caffeine; Cell Shape; Cell Survival; Cells, Cultured; Chromosomal Instability; DNA Damage; Humans; Infertility, Male; Karyotyping; Leukocytes; Male; Mitomycin; Mutagenicity Tests; Mutagens; Prospective Studies; Sister Chromatid Exchange; Sperm Count; Spermatozoa; Young Adult

2008
Antineoplastic and cytogenetic effects of chlorpromazine on human lymphocytes in vitro and on Ehrlich ascites tumor cells in vivo.
    Anti-cancer drugs, 2009, Volume: 20, Issue:8

    Topics: Animals; Antineoplastic Agents; Caffeine; Carcinoma, Ehrlich Tumor; Cell Cycle; Cell Proliferation; Cells, Cultured; Chlorpromazine; Drug Synergism; Drug Therapy, Combination; Humans; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Mitomycin; Sister Chromatid Exchange; Survival Analysis

2009
Influence of TEGDMA on the mammalian cell cycle in comparison with chemotherapeutic agents.
    Dental materials : official publication of the Academy of Dental Materials, 2010, Volume: 26, Issue:3

    Topics: Animals; Antibiotics, Antineoplastic; Caffeine; Cell Cycle; Cell Line; Cell Survival; Composite Resins; Doxorubicin; Flow Cytometry; Macrophages; Materials Testing; Mice; Mitomycin; Oxidative Stress; Phosphodiesterase Inhibitors; Polyethylene Glycols; Polymethacrylic Acids

2010