Page last updated: 2024-08-16

mitomycin and buthionine sulfoximine

mitomycin has been researched along with buthionine sulfoximine in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's9 (69.23)18.2507
2000's2 (15.38)29.6817
2010's0 (0.00)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Singh, SV; Xu, BH1
Barranco, SC; Greaves, BR; Perry, RR; Rasberry, U1
Ono, K; Shrieve, DC1
Backes, MG; Blanock, K; Emerson, EO; Jani, JP; Rihn, C; Scalamogna, D; Singh, SV; Specht, S; Stemmler, N; Xu, BH1
Lee, JH; Naito, M; Tsuruo, T1
Gupta, V; Singh, SV; Xu, BH1
Benson, PJ; Gupta, V; Hu, X; Pinto, T; Singh, S; Xia, H; Zaren, HA1
Buschini, A; Candi, A; Poli, P; Rossi, C1
Hamilton, JW; Maccubbin, AE; Warren, AJ1
Chatterjee, A; Giri, SD1
Cupissol, D; Cuq, P; Depeille, P; Evrard, A; Passagne, I; Vian, L1
Ambriovic-Ristov, A; Brozovic, A; Fritz, G; Jakopec, S; Majhen, D; Mikac, N; Osmak, M; Roje, V1
Chen, LC; Dia, YC; Jou, YC; Liu, YW; Shen, CH; Wang, SC; Wang, ST; Yang, HY; Yu, MH1

Other Studies

13 other study(ies) available for mitomycin and buthionine sulfoximine

ArticleYear
Effect of buthionine sulfoximine and ethacrynic acid on cytotoxic activity of mitomycin C analogues BMY 25282 and BMY 25067.
    Cancer research, 1992, Dec-01, Volume: 52, Issue:23

    Topics: Animals; Buthionine Sulfoximine; DNA, Neoplasm; Drug Resistance; Drug Screening Assays, Antitumor; Ethacrynic Acid; Glutathione Transferase; Leukemia P388; Methionine Sulfoximine; Mitomycin; Mitomycins; Tumor Stem Cell Assay

1992
Effect of treatment duration and glutathione depletion on mitomycin C cytotoxicity in vitro.
    Cancer research, 1992, Sep-01, Volume: 52, Issue:17

    Topics: Buthionine Sulfoximine; Cell Survival; Colonic Neoplasms; Dose-Response Relationship, Drug; Glutathione; Humans; In Vitro Techniques; Methionine Sulfoximine; Mitomycin; Tumor Cells, Cultured

1992
Enhancement of EMT6/SF tumor cell killing by mitomycin C and cyclophosphamide following in vivo administration of buthionine sulfoximine.
    International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7

    Topics: Animals; Buthionine Sulfoximine; Cyclophosphamide; Drug Synergism; Glutathione; Male; Methionine Sulfoximine; Mice; Mice, Inbred BALB C; Mitomycin; Mitomycins; Neoplasm Transplantation; Neoplasms, Experimental

1986
Mechanism of cross-resistance to cisplatin in a mitomycin C-resistant human bladder cancer cell line.
    International journal of cancer, 1995, May-04, Volume: 61, Issue:3

    Topics: Antimetabolites, Antineoplastic; Biological Transport; Buthionine Sulfoximine; Cadmium; Cadmium Chloride; Carboplatin; Cell Line; Cell Survival; Chlorides; Cisplatin; Drug Resistance; Gene Expression; Glutathione; Glutathione Transferase; Humans; Isoenzymes; Kinetics; Metallothionein; Methionine Sulfoximine; Mitomycin; RNA, Messenger; Tumor Cells, Cultured; Urinary Bladder Neoplasms

1995
Nonenzymatic reductive activation of 7-N-((2-([2-(gamma-L-glutamylamino)ethyl]dithio)ethyl))mitomycin C by thiol molecules: a novel mitomycin C derivative effective on mitomycin C-resistant tumor cells.
    Cancer research, 1994, May-01, Volume: 54, Issue:9

    Topics: Buthionine Sulfoximine; Colonic Neoplasms; Cysteine; Cytochrome P-450 Enzyme System; DNA, Neoplasm; Drug Interactions; Drug Resistance; Glutathione; Humans; Methionine Sulfoximine; Mitomycin; Mitomycins; Oxidation-Reduction; Sulfhydryl Compounds; Tumor Cells, Cultured; Tumor Stem Cell Assay

1994
Mitomycin C sensitivity in human bladder cancer cells: possible role of glutathione and glutathione transferase in resistance.
    Archives of biochemistry and biophysics, 1994, Volume: 308, Issue:1

    Topics: Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Ethacrynic Acid; Glutathione; Glutathione Transferase; Humans; Isoenzymes; Kinetics; Methionine Sulfoximine; Mitomycin; Tumor Cells, Cultured; Urinary Bladder Neoplasms

1994
Lack of a role of glutathione in cellular nonenzymatic activation of BMS-181174, a novel analogue of mitomycin C.
    Cancer research, 1996, Aug-01, Volume: 56, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Biotransformation; Buthionine Sulfoximine; Cysteine; Enzyme Inhibitors; Glutamate-Cysteine Ligase; Glutathione; Humans; Methionine Sulfoximine; Mitomycin; Mitomycins; Tumor Cells, Cultured; Urinary Bladder Neoplasms

1996
Modulation of mitomycin C mutagenicity on Saccharomyces cerevisiae by glutathione, cytochrome P-450, and mitochondria interactions.
    Mutation research, 1997, Apr-24, Volume: 390, Issue:1-2

    Topics: Buthionine Sulfoximine; Cytochrome P-450 Enzyme System; Ethyl Methanesulfonate; Gene Conversion; Glutathione; Hycanthone; Mitochondria; Mitomycin; Mutagenesis; Mutagens; Nucleic Acid Synthesis Inhibitors; Point Mutation; Saccharomyces cerevisiae

1997
Detection of mitomycin C-DNA adducts in vivo by 32P-postlabeling: time course for formation and removal of adducts and biochemical modulation.
    Cancer research, 1998, Feb-01, Volume: 58, Issue:3

    Topics: Acetylcysteine; Animals; Biotransformation; Buthionine Sulfoximine; Chick Embryo; Cross-Linking Reagents; Dexamethasone; DNA; DNA Adducts; DNA Damage; DNA Repair; Enzyme Induction; Ethacrynic Acid; Glutathione; Glutethimide; Inactivation, Metabolic; Kidney; Liver; Lung; Mitomycin; Phosphorus Radioisotopes; Polychlorinated Biphenyls; Time Factors

1998
Modulation of mitomycin C-induced sister chromatid exchanges and cell cycle delay by buthionine sulfoximine and reduced glutathione in mouse bone marrow cells in vivo.
    Mutation research, 1998, Mar-30, Volume: 413, Issue:3

    Topics: Animals; Antibiotics, Antineoplastic; Bone Marrow Cells; Buthionine Sulfoximine; Cell Cycle; Enzyme Inhibitors; Glutathione; Male; Mice; Mitomycin; Mutagenicity Tests; Nucleic Acid Synthesis Inhibitors; Sister Chromatid Exchange

1998
O(6)-methylguanine DNA-methyltransferase (MGMT) overexpression in melanoma cells induces resistance to nitrosoureas and temozolomide but sensitizes to mitomycin C.
    Toxicology and applied pharmacology, 2006, Mar-01, Volume: 211, Issue:2

    Topics: Antineoplastic Agents; Buthionine Sulfoximine; Cell Line, Tumor; Cell Survival; Dacarbazine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Inhibitory Concentration 50; Melanoma; Mitomycin; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Temozolomide; Transfection

2006
alpha(v)beta(3) Integrin-mediated drug resistance in human laryngeal carcinoma cells is caused by glutathione-dependent elimination of drug-induced reactive oxidative species.
    Molecular pharmacology, 2008, Volume: 74, Issue:1

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Buthionine Sulfoximine; Cell Line, Tumor; Cell Survival; Cisplatin; Clone Cells; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Inhibitors; Formazans; Glutathione; Humans; Integrin alphaVbeta3; Laryngeal Neoplasms; Mitomycin; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Tetrazolium Salts

2008
Anti-Cancer Effects and Tumor Marker Role of Glutathione
    International journal of molecular sciences, 2021, Mar-17, Volume: 22, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Biomarkers, Tumor; Buthionine Sulfoximine; Cell Adhesion; Cell Death; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cisplatin; DNA Methylation; Down-Regulation; Doxorubicin; Female; Gene Expression Regulation, Neoplastic; Glutathione; Glutathione Transferase; Humans; Male; Middle Aged; Mitomycin; Promoter Regions, Genetic; RNA, Messenger; Sex Characteristics; Urinary Bladder Neoplasms

2021