Page last updated: 2024-08-16

mitomycin and ascorbic acid

mitomycin has been researched along with ascorbic acid in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19904 (22.22)18.7374
1990's7 (38.89)18.2507
2000's2 (11.11)29.6817
2010's5 (27.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Arena, E; Cacciatore, I; Cerasa, LS; Di Stefano, A; Marrazzo, A; Parenti, C; Pasquinucci, L; Pittalà, V; Prezzavento, O; Turkez, H1
Beuerman, RW; Chew, SJ; Kaufman, HE1
Yuan, H; Zhang, Z1
Barriga-Arceo, SD; Madrigal-Bujaidar, E; Rivas-Olmedo, G1
Krishna, G; Nath, J; Ong, T1
Marshall, RS; Rauth, AM1
Banik, S; Deb, C; Paul, B1
Bagchi, P; Deb, C; Ghosh, KK; Majumdar, G; Mukherjee, R; Patra, PB1
Deb, C; Deb, S; Koley, BN1
Venu, R; Vijayalaxmi, KK1
Gross, RL1
Barale, R; Bosco, E; Frenzilli, G1
Lü, X; Wang, R; Zhang, L1
Krishnaja, AP; Sharma, NK1
Beiran, I; Miller, B; Pikkel, J; Yulish, M1
Paz, MM1

Reviews

1 review(s) available for mitomycin and ascorbic acid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for mitomycin and ascorbic acid

ArticleYear
Ascorbate prophylaxis with mitomycin-C for corneal haze after laser-assisted sub-epithelial keratectomy.
    The Israel Medical Association journal : IMAJ, 2012, Volume: 14, Issue:6

    Topics: Adolescent; Adult; Antioxidants; Ascorbic Acid; Astigmatism; Cornea; Corneal Opacity; Drug Therapy, Combination; Female; Humans; Keratectomy, Subepithelial, Laser-Assisted; Male; Mitomycin; Postoperative Complications; Retrospective Studies; Young Adult

2012

Other Studies

16 other study(ies) available for mitomycin and ascorbic acid

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
New bifunctional antioxidant/σ1 agonist ligands: Preliminary chemico-physical and biological evaluation.
    Bioorganic & medicinal chemistry, 2016, 07-15, Volume: 24, Issue:14

    Topics: Animals; Antioxidants; Carbon-13 Magnetic Resonance Spectroscopy; Cells, Cultured; Chromatography, High Pressure Liquid; Ligands; Male; Mass Spectrometry; Mice; Proton Magnetic Resonance Spectroscopy; Rats; Rats, Sprague-Dawley; Receptors, sigma; Sigma-1 Receptor; Spectrophotometry, Ultraviolet

2016
In vivo assessment of corneal stromal toxicity by tandem scanning confocal microscopy.
    Lens and eye toxicity research, 1992, Volume: 9, Issue:3-4

    Topics: Animals; Ascorbic Acid; Atropine; Cell Count; Cell Cycle; Cell Division; Corneal Stroma; Fibroblasts; Microscopy; Mitomycin; Rabbits; Wound Healing

1992
Some factors affecting sister-chromatid differentiation (SCD) and sister-chromatid exchange (SCE) in Hordeum vulgare.
    Mutation research, 1992, Volume: 272, Issue:2

    Topics: Analysis of Variance; Ascorbic Acid; Bromodeoxyuridine; Cell Division; Doxorubicin; Floxuridine; Free Radicals; Hordeum; Maleic Hydrazide; Mitomycin; Mutagenicity Tests; Sister Chromatid Exchange; Sulfhydryl Compounds; Temperature

1992
Inhibition of mitomycin C-induced sister chromatid exchanges by vitamin C in vivo.
    Journal of toxicology and environmental health, 1992, Volume: 35, Issue:2

    Topics: Animals; Ascorbic Acid; Bone Marrow; Cell Division; Injections, Intraperitoneal; Male; Mice; Mitomycin; Sister Chromatid Exchange

1992
Inhibition of cyclophosphamide and mitomycin C-induced sister chromatid exchanges in mice by vitamin C.
    Cancer research, 1986, Volume: 46, Issue:6

    Topics: Animals; Ascorbic Acid; Bone Marrow; Cyclophosphamide; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Mitomycin; Mitomycins; Sister Chromatid Exchange; Spleen

1986
Modification of the cytotoxic activity of mitomycin C by oxygen and ascorbic acid in Chinese hamster ovary cells and a repair-deficient mutant.
    Cancer research, 1986, Volume: 46, Issue:6

    Topics: Alkylation; Animals; Ascorbic Acid; Biotransformation; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; DNA; DNA Repair; Female; Hydrogen Peroxide; Mitomycin; Mitomycins; Mutation; Oxygen

1986
Possible role of pituitary in Mitomycin C induced inhibition of testicular steroidogenesis.
    Experimental and clinical endocrinology, 1983, Volume: 82, Issue:3

    Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Ascorbic Acid; Cholesterol; Chorionic Gonadotropin; Depression, Chemical; DNA; Glucosephosphate Dehydrogenase; Histocytochemistry; Male; Mitomycin; Mitomycins; Pituitary Gland; Rats; Steroids; Testis

1983
Possible mode of action of mitomycin C on rat ovarian steroidogenesis.
    Endokrinologie, 1981, Volume: 77, Issue:2

    Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Ascorbic Acid; Cholesterol; Female; Follicle Stimulating Hormone; Glucosephosphate Dehydrogenase; Luteinizing Hormone; Mitomycin; Mitomycins; Ovary; Rats

1981
Mitomycin C induced inhibition of adrenal steroidogenesis in female rats.
    Indian journal of physiology and pharmacology, 1994, Volume: 38, Issue:2

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenal Glands; Animals; Ascorbic Acid; Cholesterol; DNA; Female; Glucosephosphate Dehydrogenase; Hydroxysteroid Dehydrogenases; Mitomycin; Rats; Rats, Wistar; Steroids

1994
In vivo anticlastogenic effects of L-ascorbic acid in mice.
    Mutation research, 1999, Jan-02, Volume: 438, Issue:1

    Topics: Animals; Antimutagenic Agents; Ascorbic Acid; Bleomycin; Bone Marrow; Cyclophosphamide; Female; Male; Mice; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mitomycin; Mutagenicity Tests; Mutagens

1999
Collagen type I and III synthesis by Tenon's capsule fibroblasts in culture: individual patient characteristics and response to mitomycin C, 5-fluorouracil, and ascorbic acid.
    Transactions of the American Ophthalmological Society, 1999, Volume: 97

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites; Ascorbic Acid; Cells, Cultured; Child; Collagen; Conjunctiva; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Filtering Surgery; Fluorouracil; Glaucoma; Humans; Infant; Middle Aged; Mitomycin; Retrospective Studies; Sclera; Wound Healing

1999
Validation of single cell gel assay in human leukocytes with 18 reference compounds.
    Mutation research, 2000, Jul-10, Volume: 468, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; Adult; Animals; Ascorbic Acid; Benzaldehydes; Benzo(a)pyrene; Biotransformation; Bleomycin; Chlorophyllides; Cyclophosphamide; DNA Damage; Epoxy Compounds; Female; Formaldehyde; Glucose; Glutaral; Griseofulvin; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Leukocytes; Mannitol; Methylmercury Compounds; Microsomes, Liver; Mitomycin; Mutagenicity Tests; Pyrenes; Rats; Reproducibility of Results; Sodium Azide

2000
[Application of in vitro micronucleus tests using L5178Y mouse lymphoma and WTK1 human lymphoblastoid cell lines to antimutagenicity assay].
    Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 1999, Volume: 30, Issue:3

    Topics: Animals; Antimutagenic Agents; Ascorbic Acid; Chlorophyllides; Humans; Leukemia L5178; Lymphocytes; Mice; Micronucleus Tests; Mitomycin; Mutagenicity Tests; Tumor Cells, Cultured

1999
Ascorbic acid potentiates mitomycin C-induced micronuclei and sister chromatid exchanges in human peripheral blood lymphocytes in vitro.
    Teratogenesis, carcinogenesis, and mutagenesis, 2003, Volume: Suppl 1

    Topics: Adult; Antibiotics, Antineoplastic; Ascorbic Acid; Cells, Cultured; Chromosome Aberrations; Dose-Response Relationship, Radiation; Drug Synergism; Female; Free Radical Scavengers; Humans; Lymphocytes; Male; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mitomycin; Sister Chromatid Exchange

2003
Reductive activation of mitomycins A and C by vitamin C.
    Bioorganic chemistry, 2013, Volume: 48

    Topics: Animals; Ascorbic Acid; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Hydrogen-Ion Concentration; Kinetics; Mitomycin; Mitomycins; Oxidation-Reduction; Quinones; Spectrophotometry, Ultraviolet

2013