mitomycin has been researched along with allopurinol in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (28.57) | 18.7374 |
| 1990's | 9 (42.86) | 18.2507 |
| 2000's | 1 (4.76) | 29.6817 |
| 2010's | 5 (23.81) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Gustafson, DL; Pritsos, CA | 1 |
| Karvounis, N; Kosmidis, P; Tsavaris, N; Tzannou, I | 1 |
| Anada, E; Fujimura, T; Fujita, H; Haryo, S; Sawasaki, K; Shima, Y; Shiota, S | 1 |
| Gonzalez, H; Pan, SS | 1 |
| Miller, DG; Morgenstern, R; Pero, RW | 1 |
| Cullinane, C; Phillips, DR; White, RJ | 1 |
| Kikuchi, T; Komiyama, T; Sugiura, Y | 1 |
| Bachur, NR; Iracki, T; Pan, SS | 1 |
| Andrews, PA; Bachur, NR; Glover, CJ; Pan, SS | 1 |
| Gutteridge, JM; Quinlan, GJ; Wilkins, S | 1 |
| de Mol, NJ; Groot, SE; Janssen, LH; Maliepaard, M; Wolfs, A | 1 |
| Box, HC; Budzinski, EE; Ersing, N; Gurtoo, HL; Maccubbin, AE | 1 |
| Pardini, L; Pardini, RS; Shao, Y | 1 |
| Pan, SS; Yu, F | 1 |
| Mikami, K; Shirakusa, T; Tsuruo, T | 1 |
| Cowen, RL; Fitzpatrick, B; Garside, EJ; Papadopoulou, MV; Williams, KJ | 1 |
| Abd-Elgawad, HM; Motawi, TK; Shahin, NN | 1 |
3 review(s) available for mitomycin and allopurinol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[DT-diaphorase].
Topics: Antibiotics, Antineoplastic; Aziridines; Colonic Neoplasms; Cytochrome Reductases; Cytochrome-B(5) Reductase; Drug Screening Assays, Antitumor; Humans; Indolequinones; Indoles; Mitomycin; Mitomycins; NAD(P)H Dehydrogenase (Quinone); NADH, NADPH Oxidoreductases; NADPH-Ferrihemoprotein Reductase; Stomach Neoplasms; Tumor Cells, Cultured; Xanthine Dehydrogenase; Xanthine Oxidase | 1997 |
Gene therapy approaches to enhance bioreductive drug treatment.
Topics: Alkylating Agents; Animals; Anthraquinones; Breast Neoplasms; Cytochrome P-450 Enzyme System; Cytochromes; Cytochromes b5; Female; Genetic Therapy; Humans; Hypoxia; Hypoxia-Inducible Factor 1; Mice; Mitomycin; Neoplasms; Nitric Oxide Synthase; Prodrugs; Xanthine Oxidase | 2008 |
18 other study(ies) available for mitomycin and allopurinol
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Enhancement of xanthine dehydrogenase mediated mitomycin C metabolism by dicumarol.
Topics: Animals; Biotransformation; Dicumarol; Mice; Mitomycin; Oxidation-Reduction; Xanthine Dehydrogenase; Xanthine Oxidase | 1992 |
Continuous 24-hour infusion of folinic acid does not increase the response rate of 5-fluorouracil but only the toxicity.
Topics: Adult; Aged; Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Mitomycin | 1992 |
[Prophylactic effect of allopurinol mouthwash against stomatitis induced by the chemotherapy (PMUE regimen) for gastrointestinal malignancies].
Topics: Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Etoposide; Female; Gastrointestinal Neoplasms; Humans; Male; Mitomycin; Mouthwashes; Stomatitis; Tegafur; Uracil | 1991 |
Mitomycin antibiotic reductive potential and related pharmacological activities.
Topics: Animals; Colonic Neoplasms; Electrochemistry; Humans; Kinetics; Liver; Mitomycin; Mitomycins; NADH Dehydrogenase; Oxidation-Reduction; Oxygen Consumption; Rats; Tumor Cells, Cultured; Xanthine Oxidase | 1990 |
Induction of unscheduled DNA synthesis in human mononuclear leukocytes by oxidative stress.
Topics: Benzene Derivatives; Bleomycin; DNA; DNA Replication; Humans; Hydrogen Peroxide; Kinetics; Mitomycin; Mitomycins; Neutrophils; Oxygen; Xanthine; Xanthine Oxidase; Xanthines | 1986 |
DNA sequence-specific adducts of adriamycin and mitomycin C.
Topics: Base Sequence; Cations; DNA; Doxorubicin; Ferric Compounds; Ferrous Compounds; Mitomycin; Mitomycins; Molecular Sequence Data; NAD; Oxidation-Reduction; Promoter Regions, Genetic; Transcription, Genetic; Xanthine Oxidase | 1989 |
Interactions of anticancer quinone drugs, aclacinomycin A, adriamycin, carbazilquinone, and mitomycin C, with NADPH-cytochrome P-450 reductase, xanthine oxidase and oxygen.
Topics: Aclarubicin; Animals; Antineoplastic Agents; Azirines; Carbazilquinone; Doxorubicin; Drug Interactions; Electron Spin Resonance Spectroscopy; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Kinetics; Mitomycin; Mitomycins; NADPH-Ferrihemoprotein Reductase; Naphthacenes; Oxygen; Spectrophotometry, Ultraviolet; Superoxides; Xanthine Oxidase | 1986 |
DNA alkylation by enzyme-activated mitomycin C.
Topics: Alkylating Agents; Animals; Biotransformation; Cattle; Chromatography, Gel; Chromatography, High Pressure Liquid; DNA; Hydrogen-Ion Concentration; Kinetics; Mitomycin; Mitomycins; NADPH-Ferrihemoprotein Reductase; Spectrum Analysis; Xanthine Oxidase | 1986 |
Reductive activation of mitomycin C and mitomycin C metabolites catalyzed by NADPH-cytochrome P-450 reductase and xanthine oxidase.
Topics: Animals; Arsenates; Cattle; Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen-Ion Concentration; Kinetics; Mitomycin; Mitomycins; NADPH-Ferrihemoprotein Reductase; Phosphates; Rats; Xanthine Oxidase | 1984 |
Mitomycin C-induced deoxyribose degradation inhibited by superoxide dismutase. A reaction involving iron, hydroxyl and semiquinone radicals.
Topics: Animals; Benzoquinones; Cattle; Deferoxamine; Deoxyribose; Edetic Acid; Humans; Hydroxides; Hydroxyl Radical; Iron; Mitomycin; Mitomycins; Pentetic Acid; Quinones; Superoxide Dismutase; Xanthine Oxidase | 1984 |
Indoloquinone EO9: DNA interstrand cross-linking upon reduction by DT-diaphorase or xanthine oxidase.
Topics: Animals; Antineoplastic Agents; Aziridines; Biotransformation; Cross-Linking Reagents; Dicumarol; DNA; Indolequinones; Indoles; Liver; Male; Mitomycin; NAD(P)H Dehydrogenase (Quinone); Oxidation-Reduction; Rats; Rats, Wistar; Xanthine Oxidase | 1995 |
Formation of 8-hydroxyguanine in DNA during mitomycin C activation.
Topics: Anaerobiosis; Borohydrides; DNA; DNA Damage; DNA-Formamidopyrimidine Glycosylase; Guanine; Mitomycin; N-Glycosyl Hydrolases; Phosphorus Radioisotopes; Plasmids; Substrate Specificity; Xanthine Oxidase | 1994 |
Enhancement of the antineoplastic effect of mitomycin C by dietary fat.
Topics: Animals; Cytochrome Reductases; Cytochrome-B(5) Reductase; Dietary Fats; Drug Screening Assays, Antitumor; Drug Synergism; Female; Glutathione Peroxidase; Lipid Peroxidation; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB C; Mice, Nude; Mitomycin; NAD(P)H Dehydrogenase (Quinone); NADH Dehydrogenase; Random Allocation; Xanthine Dehydrogenase; Xanthine Oxidase | 1994 |
Effect of pH on DNA alkylation by enzyme-activated mitomycin C and porfiromycin.
Topics: Alkylation; Animals; Biotransformation; Cattle; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; DNA; DNA Adducts; Hydrogen-Ion Concentration; Liver; Mitomycin; NADPH-Ferrihemoprotein Reductase; Phosphodiesterase I; Phosphoric Diester Hydrolases; Porfiromycin; Rats; Xanthine Oxidase | 1993 |
Effect of protein malnutrition on the metabolism and toxicity of cisplatin, 5-fluorouracil and mitomycin C in rat stomach.
Topics: Animals; Carbon-Sulfur Lyases; Cisplatin; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Dihydrouracil Dehydrogenase (NADP); Fluorouracil; gamma-Glutamyltransferase; Gastric Mucosa; Glutathione Transferase; Male; Mitomycin; NAD(P)H Dehydrogenase (Quinone); Protein-Energy Malnutrition; Rats; Rats, Wistar; Stomach; Xanthine Oxidase | 2013 |