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mitomycin and 7-n-(4-hydroxyphenyl)mitomycin c

mitomycin has been researched along with 7-n-(4-hydroxyphenyl)mitomycin c in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199028 (96.55)18.7374
1990's1 (3.45)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hirayama, N1
Hoshi, A; Kanzawa, F; Matsushima, Y; Miyazawa, N; Saijo, N; Shimizu, E1
Kollman, PA; Rao, SN; Remers, WA; Wunz, TP1
Eguchi, K; Fujita, J; Futami, H; Hoshi, A; Saijo, N; Sasaki, Y; Shimizu, E; Shinkai, T; Tominaga, K1
Matsumura, Y; Nasu, Y; Obama, T; Ochi, J; Ohmori, H; Tsushima, T; Yoshimoto, J1
Asanuma, F1
Takahashi, H; Takahashi, K; Wakui, A; Yokoyama, M1
Ochi, K; Tanaka, N1
Komano, T; Ueda, K1
Komano, T; Morita, J; Ueda, K1
Imai, R; Morimoto, M1
Fujioka, Y; Hoshi, A; Saijo, N; Shibuya, M; Shimizu, E; Takizawa, T1
Fujiwara, K; Hara, K; Kitagawa, T; Nakamura, H; Nakamura, N; Saito, A1
Abe, M; Chinen, T; Isogai, Y; Kobayashi, T; Kuraishi, Y; Meguro, S; Nagata, T; Yamazaki, H; Yokoyama, K1
Harashima, S; Kanko, T; Nakao, I; Nishi, I; Ohashi, Y; Saito, T; Yokoyama, T1
Chinen, T; Isogai, Y; Kobayashi, T; Meguro, S; Nagata, T; Ogawa, M; Yamazaki, H; Yokoyama, K1
Habu, H; Hoshi, K; Ochi, K; Sunagawa, M; Takeshita, K; Tanaka, N1
Eguchi, K; Garcia-Herreros, P; Hoshi, A; Nomori, H; Saijo, N; Sasaki, Y; Shimizu, E; Shinkai, T; Tominaga, K1
Imai, R; Morimoto, M; Okabe, M1
Imai, R; Inaba, M; Kobayashi, T; Marumo, H; Morimoto, M; Sakurai, Y; Tsukagoshi, S; Tsuruo, T1
Imai, R; Inaba, M; Kobayashi, T; Morimoto, M; Sakurai, Y; Tsukagoshi, S1
Imai, R; Marumo, H; Morimoto, M1
Kobayashi, Y; Sato, H; Taguchi, H1
Fujita, H1
Eguchi, K; Saijo, N; Shibuya, M; Shimabukuro, Z; Shimizu, E; Shinkai, T; Tominaga, K1
Hashimoto, Y; Okamoto, T; Shudo, K1
Deguchi, T; Nakamizo, N; Okumura, S1
Ashizawa, T; Imai, R; Morimoto, M; Nakamura, N; Urakawa, C1

Other Studies

29 other study(ies) available for mitomycin and 7-n-(4-hydroxyphenyl)mitomycin c

ArticleYear
Structure studies of mitomycins. III. Structure of M-83.
    Acta crystallographica. Section C, Crystal structure communications, 1990, Oct-15, Volume: 46 ( Pt 10)

    Topics: Animals; Antibiotics, Antineoplastic; Crystallization; Leukemia P388; Mitomycin; Mitomycins; Molecular Structure; Thermodynamics; X-Ray Diffraction

1990
Evaluation of a new drug 7-N-(p-hydroxyphenyl)-mitomycin C [KW 2083] against carcinoma of the lung by the human tumor clonogenic assay.
    Investigational new drugs, 1985, Volume: 3, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Colony-Forming Units Assay; Drug Evaluation; Humans; Lung Neoplasms; Mitomycin; Mitomycins; Tumor Stem Cell Assay

1985
Conformations of complexes between mitomycins and decanucleotides. 3. Sequence specificity, binding at C-10, and mitomycin analogues.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:8

    Topics: Animals; Base Sequence; Binding Sites; Chemical Phenomena; Chemistry; DNA; Leukemia P388; Mice; Mitomycin; Mitomycins; Models, Molecular; Molecular Conformation; Oligodeoxyribonucleotides

1988
Phase II study of 7-N-(p-hydroxyphenyl)-mitomycin C (KW2083) in patients with advanced non-small cell carcinoma of the lung and metastatic pulmonary tumors.
    Japanese journal of clinical oncology, 1985, Volume: 15, Issue:1

    Topics: Adult; Aged; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Middle Aged; Mitomycin; Mitomycins; Thrombocytopenia

1985
[Effect of KW-2083 in Stage D adenocarcinoma of the prostate].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:5

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Drug Administration Schedule; Humans; Male; Mitomycin; Mitomycins; Prostatic Neoplasms

1985
Antitumor activity and pharmacokinetics of 7-N-(p-hydroxyphenyl)mitomycin C in human tumor xenografts transplanted into nude mice.
    The Journal of antibiotics, 1985, Volume: 38, Issue:3

    Topics: Animals; Antibiotics, Antineoplastic; Autoradiography; Humans; Kidney; Kinetics; Liver; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitomycin; Mitomycins; Neoplasm Transplantation; Neoplasms, Experimental; Transplantation, Heterologous

1985
[A clinical trial of a new mitomycin C derivative, KW-2083 (7-N-(p-hydroxyphenyl)-mitomycin C)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:9

    Topics: Adult; Aged; Animals; Antibiotics, Antineoplastic; Biliary Tract Neoplasms; Colonic Neoplasms; Colony-Forming Units Assay; Drug Evaluation; Female; Humans; Injections, Intravenous; Male; Mice; Middle Aged; Mitomycin; Mitomycins; Neoplasms; Ovarian Neoplasms; Stomach Neoplasms

1985
Sequential changes of nuclear DNA content caused by chemotherapy in experimental canine gastric cancer.
    Gastroenterologia Japonica, 1985, Volume: 20, Issue:6

    Topics: Animals; Cell Cycle; DNA, Neoplasm; Dogs; Endoscopy; Female; Male; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Ploidies; Stomach Neoplasms

1985
Sequence-specific DNA damage induced by reduced mitomycin C and 7-N-(p-hydroxyphenyl)mitomycin C.
    Nucleic acids research, 1984, Sep-11, Volume: 12, Issue:17

    Topics: Bacteriophage phi X 174; Base Sequence; Borohydrides; Chelating Agents; Dithiothreitol; DNA Restriction Enzymes; DNA, Viral; Kinetics; Mitomycin; Mitomycins; Oxidation-Reduction; Sodium Chloride

1984
Phage inactivation and DNA strand scission activities of 7-N-(p-hydroxyphenyl)mitomycin C.
    The Journal of antibiotics, 1982, Volume: 35, Issue:10

    Topics: Bacteriophage phi X 174; Bacteriophages; DNA, Viral; Electrophoresis, Agar Gel; Mitomycin; Mitomycins; Pseudomonas

1982
Comparative antitumor activities of 7-N-(p-hydroxyphenyl)mitomycin C (M-83) and mitomycin C.
    The Journal of antibiotics, 1983, Volume: 36, Issue:5

    Topics: Animals; Antibiotics, Antineoplastic; HeLa Cells; Male; Mice; Mice, Inbred Strains; Mitomycin; Mitomycins; Neoplasms, Experimental

1983
[In vitro antitumor activity of 7-N-(p-hydroxyphenyl)-mitomycin C (KW-2083) against cultured bronchogenic carcinoma cells (PC-7)].
    Gan no rinsho. Japan journal of cancer clinics, 1983, Volume: 29, Issue:11

    Topics: Carcinoma, Bronchogenic; Cell Line; Cells, Cultured; Drug Evaluation; Humans; Lung Neoplasms; Mitomycin; Mitomycins

1983
Development and application of a sensitive enzyme immunoassay for 7-N-(p-hydroxyphenyl)mitomycin C.
    Cancer research, 1984, Volume: 44, Issue:9

    Topics: Antibodies; beta-Galactosidase; Haptens; Humans; Immunoenzyme Techniques; Indicators and Reagents; Kinetics; Mitomycin; Mitomycins

1984
[Phase I-II study of 7-N-(P-hydroxyphenyl)-mitomycin C (KW2083, M83)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:9

    Topics: Aged; Antibiotics, Antineoplastic; Breast Neoplasms; Colonic Neoplasms; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Middle Aged; Mitomycin; Mitomycins; Nausea; Neoplasms; Stomach Neoplasms; Vomiting

1984
[Phase II study of KW 2083 [7-N-(p-hydroxyphenyl)-mitomycin C] in patients with various cancers].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:12 Pt 1

    Topics: Adolescent; Adult; Aged; Alanine Transaminase; Anorexia; Antibiotics, Antineoplastic; Aspartate Aminotransferases; Colonic Neoplasms; Drug Evaluation; Esophageal Neoplasms; Female; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Mitomycin; Mitomycins; Nausea; Neoplasms; Stomach Neoplasms

1984
Phase I study of 7-N-(p-hydroxyphenyl)-mitomycin C.
    Investigational new drugs, 1984, Volume: 2, Issue:4

    Topics: Aged; Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Middle Aged; Mitomycin; Mitomycins; Pancreatic Neoplasms; Stomach Neoplasms

1984
Sequential changes in nuclear DNA content by chemotherapy observed in experimental canine gastric cancer.
    Gastroenterologia Japonica, 1984, Volume: 19, Issue:6

    Topics: Adenocarcinoma; Animals; Carcinogens; Cell Nucleus; DNA, Neoplasm; Dogs; Flow Cytometry; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Stomach Neoplasms

1984
[Effect of 7-N-(P-hydroxyphenyl)-mitomycin C (KW-2083) against pleuritis carcinomatosa].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Anorexia; Antineoplastic Agents; Colonic Neoplasms; Female; Fever; Humans; Lung Neoplasms; Male; Middle Aged; Mitomycin; Mitomycins; Nausea; Ovarian Neoplasms; Pain; Pleurisy; Thorax

1984
The action of 7-N-(p-hydroxyphenyl)mitomycin C [M-83] in suppressing murine immune response.
    The Journal of antibiotics, 1982, Volume: 35, Issue:8

    Topics: Animals; Antibiotics, Antineoplastic; Hemolytic Plaque Technique; Hypersensitivity, Delayed; Immunosuppressive Agents; Leukemia P388; Lymphocyte Activation; Mice; Mice, Inbred Strains; Mitomycin; Mitomycins; Spleen

1982
Antitumor activity of 7-n-(p-hydroxyphenyl)-mitomycin C in experimental tumor systems.
    Gan, 1981, Volume: 72, Issue:6

    Topics: Animals; Carcinoma; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fibrosarcoma; Leukemia P388; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Mitomycin; Mitomycins; Neoplasms, Experimental; Sarcoma 180

1981
Comparison of the hematologic toxicity of 7-N-(p-hydroxyphenyl),-mitomycin C and mitomycin C.
    Gan, 1981, Volume: 72, Issue:6

    Topics: Animals; Bone Marrow; Drug Evaluation, Preclinical; Hematopoiesis; Leukocytes; Male; Mice; Mitomycin; Mitomycins; Time Factors

1981
Distribution and excretion of 7-N-(p-hydroxyphenyl)-mitomycin C in normal mice.
    Gan, 1982, Volume: 73, Issue:4

    Topics: Animals; Antibiotics, Antineoplastic; In Vitro Techniques; Inactivation, Metabolic; Injections, Intraperitoneal; Injections, Intravenous; Kinetics; Liver; Male; Mice; Mitomycin; Mitomycins; Tissue Distribution

1982
[Antitumor spectrum of 7-N-(p-hydroxyphenyl) mitomycin C (KW 2083) in rat ascites hepatoma].
    Gan no rinsho. Japan journal of cancer clinics, 1982, Volume: 28, Issue:2

    Topics: Animals; Drug Evaluation, Preclinical; Female; Liver Neoplasms, Experimental; Mitomycin; Mitomycins; Rats

1982
[Pharmacokinetics of mitomycin C and its derivative (KW-2083)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:8

    Topics: Animals; Antibiotics, Antineoplastic; Humans; Infusions, Parenteral; Kinetics; Mice; Mitomycin; Mitomycins

1982
[Phase II study of KW2083 [7-N-(p-hydroxyphenyl)-mitomycin C] in patients with carcinoma of the lung and metastatic pulmonary tumor].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:3

    Topics: Adenocarcinoma; Adult; Antibiotics, Antineoplastic; Carcinoma, Squamous Cell; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Middle Aged; Mitomycin; Mitomycins; Teratoma

1983
Alkylation of DNA with a mitomycin derivative, 7-N-(p-hydroxyphenyl)-mitomycin C. Reductive alkylation nd preferential binding to adenine.
    Chemical & pharmaceutical bulletin, 1982, Volume: 30, Issue:7

    Topics: Adenine; Alkylation; Animals; DNA; Mitomycin; Mitomycins; Oxidation-Reduction; Rats

1982
[Studies on the physiological disposition and pharmacokinetics of 7-N-(p-hydroxyphenyl)-mitomycin C].
    The Japanese journal of antibiotics, 1982, Volume: 35, Issue:8

    Topics: Animals; Bile; Carbon Radioisotopes; Dogs; Feces; Female; Injections, Intravenous; Intestinal Absorption; Kinetics; Male; Maternal-Fetal Exchange; Mitomycin; Mitomycins; Pregnancy; Rats; Rats, Inbred Strains; Tissue Distribution

1982
[Phase I study of KW2083 7-N-(p-hydroxyphenyl) mitomycin C].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:10

    Topics: Animals; Anorexia; Drug Evaluation; Humans; Mice; Mitomycin; Mitomycins; Nausea; Neoplasms; Vomiting

1982
Antitumor activity of 7-N-phenyl derivatives of mitomycin C in the leukemia P388 system.
    Gan, 1980, Volume: 71, Issue:4

    Topics: Animals; Leukemia P388; Leukemia, Experimental; Mice; Mitomycin; Mitomycins; Structure-Activity Relationship

1980