mitomycin has been researched along with 4-nitroquinoline-1-oxide in 54 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (48.15) | 18.7374 |
| 1990's | 16 (29.63) | 18.2507 |
| 2000's | 9 (16.67) | 29.6817 |
| 2010's | 2 (3.70) | 24.3611 |
| 2020's | 1 (1.85) | 2.80 |
| Authors | Studies |
|---|---|
| Anderson, RF; Denny, WA; Thompson, LH; Wilson, WR | 1 |
| Brun, R; Jędrysiak, R; Kaiser, M; Suwiński, J; Torreele, E; Trunz, BB; Tweats, D | 1 |
| Masek, F; Sedliaková, M | 1 |
| Nakayama, H; Shiota, S; Umezu, K | 1 |
| Cortés, F; Daza, P; Escalza, P; Mateos, S | 1 |
| Cortés, F; Daza, P; Escalza, P; Piñero, J | 1 |
| Astemborski, JA; Boughman, JA; Budacz, AP; Cohen, MM; Schwartz, S; Wasserman, SS | 1 |
| Cohen, MM; Schwartz, S; Wasserman, SS | 1 |
| Inoue, H; Ishii, C; Nakamura, K | 1 |
| Nishioka, H; Nunoshiba, T | 1 |
| Fukuda, I; Morita, T; Nagaki, T; Okumura, K | 1 |
| Simons, JW; Zdzienicka, MZ | 1 |
| Pattee, PA; Tam, JE | 1 |
| Imanishi, H; Matsumoto, K; Nakamura, Y; Noro, T; Sasaki, YF; Shimoi, K; Shirasu, Y; Tomita, I | 1 |
| Bale, AE; Bale, SJ; Ivett, J; Mulvihill, JJ; Murli, H; Parry, DM | 1 |
| Inoue, H; Ishii, C | 1 |
| Katayama, S; Matsumoto, N | 1 |
| Lakdawalla, AA; Netrawali, MS | 1 |
| Koizumi, A; Miura, K; Morimoto, K | 1 |
| Iijima, K; Morimoto, K | 1 |
| Oikawa, A; Tohda, H | 1 |
| Hama-Inaba, H; Hieda-Shiomi, N; Ito, A; Sato, K; Shiomi, T | 1 |
| Galloway, SM; Ivett, JL; Mulvihill, JJ; Murli, H; Parry, DM | 2 |
| Jeffrey, AM | 1 |
| Butler, MA; Connor, TH; Inman, MA; Matney, TS | 1 |
| Bootsma, D; de Wit, J; Jaspers, NG; Regulski, MR | 1 |
| Boling, ME; Jones, MH; Lee, WH; Volkin, E | 1 |
| Akamatsu, N; Miyaki, M; Ono, T; Sasaki, MS; Suzuki, K | 1 |
| Arlett, CF; Broughton, BC; Harcourt, SA; Priestley, A; Teo, IA | 1 |
| Ikenaga, M; Kitamura, H; Miyamoto, M; Tsujimura, T; Utsunomiya, J | 1 |
| Alldrick, AJ; Rowland, IR | 1 |
| Morimoto, K | 1 |
| Iijima, K; Kaneko, T; Koizumi, A; Miura, K; Morimoto, K; Sato, M | 1 |
| Ohno, K; Takeshita, K | 1 |
| Buchwald, M; Ishida, R | 1 |
| Nohmi, T; Ohta, T; Watanabe, M | 1 |
| Gasiorowski, K; Szyba, K; Urban, J | 1 |
| Antonelli, A; Elli, R; Marcucci, L; Petrinelli, P | 1 |
| Miyahara, T; Sasaki, YF; Yamada, H | 1 |
| Jin, ZC; Qian, J | 1 |
| Kubis, S; Quiñones, A; Wandt, G | 1 |
| Bourner, C; Fedyk, J; Henderson, L; Windebank, S; Wolfreys, A | 1 |
| Barale, R; Bosco, E; Frenzilli, G | 1 |
| Quiñones, A; Rainov, NG | 1 |
| Furuichi, Y; Goto, M; Hayashi, M; Honma, M; Sakamoto, H; Satoh, T; Sofuni, T; Sugimoto, M; Tadokoro, S; Tanabe, H | 1 |
| De Kimpe, N; Elgorashi, EE; Kestens, V; Maes, A; Taylor, JL; Van Puyvelde, L; Van Staden, J; Verschaeve, L | 1 |
| Bau, DT; Chien, YH; Jan, KY | 1 |
| Baohong, W; Deqiang, L; Hongping, D; Jianlin, L; Jiliang, H; Lifen, J; Wei, Z | 1 |
| Deng, HP; He, JL; Jin, LF; Li, QY; Lou, JL; Lu, DQ; Wang, BH; Zheng, W | 1 |
| Fellows, MD; O'Donovan, MR | 1 |
| Gopinath, PM; Jayaraman, G; Mohapatra, R; Ramesh, A; Santhiya, ST | 1 |
| Abraham, SK; Hintzsche, H; Khandelwal, N; Stopper, H | 1 |
| Helbling, FR; Huber, A; McHugh, D; Smart, DJ; Vanscheeuwijck, P; Verardo, M | 1 |
1 review(s) available for mitomycin and 4-nitroquinoline-1-oxide
| Article | Year |
|---|---|
DNA modification by chemical carcinogens.
Topics: 4-Nitroquinoline-1-oxide; Aflatoxins; Alkylating Agents; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzodiazepinones; Biotransformation; Carcinogens; Chemical Phenomena; Chemistry; Chrysenes; DNA; DNA Replication; Epoxy Compounds; Fluorenes; Furocoumarins; Humans; Immunologic Techniques; Isotope Labeling; Mitomycin; Mitomycins; Naphthalenes; Oxides; Platinum; Pyrenes; Safrole; Spectrometry, Fluorescence | 1985 |
53 other study(ies) available for mitomycin and 4-nitroquinoline-1-oxide
| Article | Year |
|---|---|
Hypoxia-selective antitumor agents. 2. Electronic effects of 4-substituents on the mechanisms of cytotoxicity and metabolic stability of nitracrine derivatives.
Topics: Aminoacridines; Animals; Cell Division; Cell Line; DNA; Nitracrine; Oxygen; Structure-Activity Relationship | 1989 |
1-Aryl-4-nitro-1H-imidazoles, a new promising series for the treatment of human African trypanosomiasis.
Topics: Animals; Antiprotozoal Agents; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Leukocytes, Mononuclear; Mice; Molecular Structure; Mutagenicity Tests; Nitroimidazoles; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Trypanosomiasis, African | 2011 |
Inducible stable DNA replication in Escherichia coli uvr+ and uvr- cells, treated with genotoxic chemicals.
Topics: 4-Nitroquinoline-1-oxide; 4-Quinolones; Acrylates; Anti-Infective Agents; Chloramphenicol; DNA Replication; Escherichia coli; Furans; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methylnitrosourea; Mitomycin; Mutagens; Nalidixic Acid; Nitro Compounds; Nitrofurans | 1992 |
UV endonuclease-mediated enhancement of UV survival in Micrococcus luteus: evidence revealed by deficiency in the Uvr homolog.
Topics: 4-Nitroquinoline-1-oxide; Dose-Response Relationship, Radiation; Endodeoxyribonucleases; Micrococcus luteus; Mitomycin; Multienzyme Complexes; N-Glycosyl Hydrolases; Ultraviolet Rays | 1992 |
Mitomycin C, 4-nitroquinoline-1-oxide and ethyl methanesulfonate induce long-lived lesions in DNA which result in SCEs during successive cell cycles in human lymphocytes.
Topics: 4-Nitroquinoline-1-oxide; Cell Cycle; DNA; DNA Damage; Ethyl Methanesulfonate; Humans; Lymphocytes; Mitomycin; Mutagenesis; Mutagens; Sister Chromatid Exchange; Time Factors | 1992 |
Different effectiveness of 4-nitroquinoline-1-oxide, mitomycin C and ethyl methanesulfonate to induce lesions in DNA leading to sister chromatid exchange throughout successive cell cycles in Chinese hamster ovary cells.
Topics: 4-Nitroquinoline-1-oxide; Animals; Cell Cycle; CHO Cells; Cricetinae; DNA; DNA Damage; DNA Repair; Ethyl Methanesulfonate; Mitomycin; Sister Chromatid Exchange | 1992 |
Repeated measurement of spontaneous and clastogen-induced sister-chromatid exchange.
Topics: 4-Nitroquinoline-1-oxide; Bleomycin; Humans; Lymphocytes; Mitomycin; Mitomycins; Mutagens; Reference Values; Sister Chromatid Exchange; Streptonigrin | 1990 |
Factors underlying variation in spontaneous and clastogen-induced sister chromatid exchanges and chromosome breakage frequencies.
Topics: 4-Nitroquinoline-1-oxide; Adult; Alkylating Agents; Bleomycin; Chromosome Aberrations; Female; Humans; Male; Middle Aged; Mitomycin; Mitomycins; Mutagens; Regression Analysis; Sister Chromatid Exchange; Streptonigrin | 1990 |
A novel phenotype of an excision-repair mutant in Neurospora crassa: mutagen sensitivity of the mus-18 mutant is specific to UV.
Topics: 4-Nitroquinoline-1-oxide; Alkylating Agents; Chromosome Mapping; DNA Damage; DNA Repair; DNA, Bacterial; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electrophoresis, Agar Gel; Epistasis, Genetic; Gamma Rays; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Mutation; Neurospora crassa; Phenotype; Ultraviolet Rays | 1991 |
'Rec-lac test' for detecting SOS-inducing activity of environmental genotoxic substance.
Topics: 4-Nitroquinoline-1-oxide; Alkylating Agents; beta-Galactosidase; Cloning, Molecular; DNA Repair; Escherichia coli; Genes, Bacterial; Kinetics; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Mutagenicity Tests; Mutagens; Oxidation-Reduction; Rec A Recombinases; SOS Response, Genetics; Ultraviolet Rays | 1991 |
Effect of pH on the activity and stability of clastogens in the in vitro chromosomal aberration test with Chinese hamster ovary K1 cells.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Cells, Cultured; Chromatography, High Pressure Liquid; Chromosome Aberrations; Cricetinae; Culture Media; Dimethylnitrosamine; Female; Half-Life; Hydrogen-Ion Concentration; In Vitro Techniques; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Mutagens | 1991 |
Analysis of repair processes by the determination of the induction of cell killing and mutations in two repair-deficient Chinese hamster ovary cell lines.
Topics: 4-Nitroquinoline-1-oxide; Alkylating Agents; Animals; Bleomycin; Cell Line; Cricetinae; DNA Repair; Drug Resistance; Female; Fibroblasts; Guanine; Hypoxanthine Phosphoribosyltransferase; Mitomycin; Mitomycins; Mutagens; Ovary; Sodium-Potassium-Exchanging ATPase; Ultraviolet Rays | 1986 |
Characterization and genetic mapping of a mutation affecting apurinic endonuclease activity in Staphylococcus aureus.
Topics: 4-Nitroquinoline-1-oxide; Chromosome Mapping; Chromosomes, Bacterial; Deoxyribonuclease IV (Phage T4-Induced); DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; Endodeoxyribonucleases; Ethyl Methanesulfonate; Genes, Bacterial; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Mutation; Nitrous Acid; Recombination, Genetic; Staphylococcus aureus; Ultraviolet Rays | 1986 |
Enhancing effects of cinoxate and methyl sinapate on the frequencies of sister-chromatid exchanges and chromosome aberrations in cultured mammalian cells.
Topics: 4-Nitroquinoline-1-oxide; Animals; Cell Line; Chromosome Aberrations; Cinnamates; Cricetinae; DNA Repair; Humans; In Vitro Techniques; Mitomycin; Mitomycins; Mutation; Sister Chromatid Exchange; Ultraviolet Rays; Xeroderma Pigmentosum | 1989 |
Sister chromatid exchange and chromosome fragility in the nevoid basal cell carcinoma syndrome.
Topics: 4-Nitroquinoline-1-oxide; Adult; Basal Cell Nevus Syndrome; Carcinoma, Basal Cell; Cells, Cultured; Chromosome Fragility; Female; Humans; Lymphocytes; Male; Methylnitronitrosoguanidine; Middle Aged; Mitomycin; Mitomycins; Sister Chromatid Exchange | 1989 |
Epistasis, photoreactivation and mutagen sensitivity of DNA repair mutants upr-1 and mus-26 in Neurospora crassa.
Topics: 4-Nitroquinoline-1-oxide; Aminacrine; DNA Repair; Dose-Response Relationship, Radiation; Gamma Rays; Genotype; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Mutagens; Mutation; Neurospora; Neurospora crassa; Nitrogen Mustard Compounds; Ultraviolet Rays | 1989 |
Toxic effects of chemicals on mouse post-blastocyst development--a trial to establish a testing system for embryotoxicity.
Topics: 4-Nitroquinoline-1-oxide; Animals; Antibiotics, Antineoplastic; Blastocyst; Bleomycin; Chromosome Aberrations; Embryonic and Fetal Development; Embryonic Development; Female; Mercuric Chloride; Methylmercury Compounds; Mice; Mice, Inbred ICR; Mitomycin; Mitomycins; Pregnancy | 1985 |
Mutagenicity, comutagenicity, and antimutagenicity of erythrosine (FD and C red 3), a food dye, in the Ames/Salmonella assay.
Topics: 4-Nitroquinoline-1-oxide; Animals; Azides; Benzo(a)pyrene; Carbolines; Cecum; DNA Damage; DNA Repair; Drug Interactions; Erythrosine; Ethidium; Fluoresceins; Food Coloring Agents; Harmine; Male; Methyl Methanesulfonate; Microsomes, Liver; Mitomycin; Mitomycins; Mutation; Rats; Rats, Inbred Strains; Salmonella typhimurium; Sodium Azide | 1988 |
Effects of temperature on chemically induced sister-chromatid exchange in human lymphocytes.
Topics: 4-Nitroquinoline-1-oxide; Cell Cycle; Ethyl Methanesulfonate; Humans; In Vitro Techniques; Mitomycin; Mitomycins; Mutagenicity Tests; Sister Chromatid Exchange; Temperature | 1986 |
Cell-stage dependence of mutagen-induced sister-chromatid exchanges in human lymphocyte cultures.
Topics: 4-Nitroquinoline-1-oxide; Adult; Cell Cycle; Cells, Cultured; Ethyl Methanesulfonate; Female; Humans; Lymphocytes; Mitomycin; Mitomycins; Mutagens; Sister Chromatid Exchange | 1986 |
Proliferation-dependent reduction of sister-chromatid exchange frequency induced by mitomycin C in human lymphoblastoid cells and its suppression by inhibitors of DNA replication.
Topics: 4-Nitroquinoline-1-oxide; Cell Division; Cycloheximide; Cytarabine; Depression, Chemical; DNA Repair; DNA Replication; Ethyl Methanesulfonate; Humans; Hydroxyurea; Lymphocytes; Mitomycin; Mitomycins; Sister Chromatid Exchange | 1986 |
Mutagen detection with a mouse line containing 3 distinct mutations conferring sensitivity.
Topics: 4-Nitroquinoline-1-oxide; Animals; Cell Line; Cross-Linking Reagents; DNA Repair; Drug Resistance; Leukemia L5178; Methyl Methanesulfonate; Mice; Mitomycin; Mitomycins; Mutagenicity Tests; Mutation; Radiation Tolerance; Ultraviolet Rays; X-Rays | 1987 |
Baseline and mutagen-induced sister-chromatid exchanges in cultures of human whole blood and purified fresh or frozen lymphocytes.
Topics: 4-Nitroquinoline-1-oxide; Blood Cells; Cells, Cultured; Freezing; Humans; In Vitro Techniques; Lymphocytes; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Mutagens; Preservation, Biological; Sister Chromatid Exchange; Smoking | 1987 |
Repair of sister-chromatid exchange-inducing lesions in mutagen-treated cultures of human whole blood and purified fresh or frozen lymphocytes.
Topics: 4-Nitroquinoline-1-oxide; DNA Repair; Female; Freezing; Humans; In Vitro Techniques; Lymphocytes; Male; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Preservation, Biological; Sister Chromatid Exchange; Smoking | 1988 |
The effects of excision repair and the plasmid pKM101 on the induction of his+ revertants by chemical agents in Salmonella typhimurium.
Topics: 4-Nitroquinoline-1-oxide; Aminacrine; Antibiotics, Antineoplastic; DNA Repair; Histidine; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Mutagenicity Tests; Mutagens; Mutation; Plasmids; Salmonella typhimurium | 1983 |
Abnormal regulation of DNA replication and increased lethality in ataxia telangiectasia cells exposed to carcinogenic agents.
Topics: 4-Nitroquinoline-1-oxide; Alkylating Agents; Ataxia Telangiectasia; Bleomycin; Carcinogens; Cell Survival; Cells, Cultured; DNA Repair; DNA Replication; Humans; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Niacinamide; Oxygen; X-Rays | 1982 |
The effect of chemical mutagens on purine and pyrimidine nucleotide biosynthesis.
Topics: 4-Nitroquinoline-1-oxide; Adenosine Triphosphate; Aminacrine; Animals; Cytidine Triphosphate; Cytosine Nucleotides; DNA Replication; Guanosine Triphosphate; Kinetics; Liver Neoplasms, Experimental; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Mutagens; Rats; Transcription, Genetic; Uracil Nucleotides; Uridine Triphosphate | 1983 |
Mechanism of increased susceptibility to 4-nitroquinoline-1-oxide in cultured skin fibroblasts from patients with familial polyposis coli.
Topics: 4-Nitroquinoline-1-oxide; Cell Survival; Cells, Cultured; Centrifugation, Density Gradient; Colonic Neoplasms; DNA; Dose-Response Relationship, Drug; Drug Resistance; Humans; Intestinal Polyps; Mitomycin; Mitomycins; Nitroquinolines; Skin | 1983 |
Multiple hypersensitivity to mutagens in a cell strain (46BR) derived from a patient with immuno-deficiencies.
Topics: 4-Nitroquinoline-1-oxide; Agammaglobulinemia; Alkylating Agents; Cell Line; Cell Survival; DNA Repair; Fibroblasts; Humans; Mitomycin; Mitomycins; Mutagens; Ultraviolet Rays | 1983 |
Increased sensitivity of cultured fibroblasts from colon cancer-prone rats to cytotoxicity of carcinogens and to viral transformation: a comparison with fibroblasts from patients with adenomatosis coli.
Topics: 4-Nitroquinoline-1-oxide; Adenoma; Animals; Carcinogens; Cell Division; Cell Survival; Cell Transformation, Viral; Cells, Cultured; Colonic Neoplasms; Drug Resistance; Female; Fibroblasts; Humans; Kirsten murine sarcoma virus; Male; Mice; Mice, Inbred BALB C; Mitomycin; Mitomycins; Neoplasms, Multiple Primary; Radiation Tolerance; Rats; Rats, Inbred WF; Rectal Neoplasms; Skin; Ultraviolet Rays | 1983 |
Exposure to low concentrations of mutagens alters the mutagenic and lethal effects of 4-nitroquinoline-N-oxide and mitomycin C in Escherichia coli.
Topics: 4-Nitroquinoline-1-oxide; DNA Repair; Dose-Response Relationship, Drug; Escherichia coli; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Mutation; Nitroquinolines | 1984 |
Proliferative kinetics and chemical-induced sister chromatid exchanges in human lymphocyte cultures.
Topics: 4-Nitroquinoline-1-oxide; Cell Cycle; Cell Division; Cells, Cultured; DNA Repair; DNA Replication; Ethyl Methanesulfonate; Humans; Lymphocytes; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Nitrosourea Compounds; Sister Chromatid Exchange | 1984 |
Human health situation and chromosome alterations: sister chromatid exchange frequency in lymphocytes from passive smokers and patients with hereditary diseases.
Topics: 4-Nitroquinoline-1-oxide; Adolescent; Adult; Alzheimer Disease; Anemia, Aplastic; Cell Cycle; Cells, Cultured; Child; Colonic Polyps; Fanconi Anemia; Female; Gardner Syndrome; Humans; Lymphocytes; Male; Methylnitronitrosoguanidine; Middle Aged; Mitomycin; Mitomycins; Sister Chromatid Exchange; Tobacco Smoke Pollution | 1984 |
Patients with tuberous sclerosis have fibroblasts with normal limits for growth characteristics and sensitivities to DNA alkylating agents.
Topics: 4-Nitroquinoline-1-oxide; Adolescent; Adult; Cell Division; Cell Survival; Cells, Cultured; Child; DNA Repair; Ethyl Methanesulfonate; Fibroblasts; Humans; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Skin; Tuberous Sclerosis | 1984 |
Susceptibility of Fanconi's anemia lymphoblasts to DNA-cross-linking and alkylating agents.
Topics: 4-Nitroquinoline-1-oxide; Alkylating Agents; Anemia, Aplastic; Antibiotics, Antineoplastic; Carcinogens; Cell Line; Cell Survival; Cross-Linking Reagents; DNA; Epoxy Compounds; Fanconi Anemia; Humans; Lymphocytes; Mitomycin; Mitomycins; Nitrosourea Compounds; Xeroderma Pigmentosum | 1982 |
Effects of the umuDC, mucAB, and samAB operons on the mutational specificity of chemical mutagenesis in Escherichia coli: I. Frameshift mutagenesis.
Topics: 4-Nitroquinoline-1-oxide; Alleles; Aminacrine; DNA Mutational Analysis; DNA, Bacterial; Escherichia coli; Frameshift Mutation; Furylfuramide; Lac Operon; Methylnitronitrosoguanidine; Mitomycin; Mutagenesis, Site-Directed; Mutagens; Nitrogen Mustard Compounds; Operon; Plasmids; SOS Response, Genetics; Suppression, Genetic | 1994 |
Todralazine influence upon the mutagenicity of some direct- and indirect-acting mutagens.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Aminacrine; Antimutagenic Agents; Azides; Benzo(a)pyrene; Biotransformation; Daunorubicin; Dose-Response Relationship, Drug; Methyl Methanesulfonate; Methylcholanthrene; Microsomes, Liver; Mitomycin; Mutagenicity Tests; Mutagens; Salmonella typhimurium; Sodium Azide; Todralazine | 1994 |
Expression of genes carried by pR plasmid in damaged E. coli and mouse cells.
Topics: 4-Nitroquinoline-1-oxide; Animals; Bacterial Proteins; Bleomycin; Cell Line; Cisplatin; DNA Damage; DNA Repair; DNA Transposable Elements; DNA-Binding Proteins; Escherichia coli; Escherichia coli Proteins; Gene Expression; Gentamicins; Methylnitronitrosoguanidine; Mice; Mitomycin; Mutagens; Plasmids; RNA, Messenger; Transcription, Genetic; Ultraviolet Rays | 1994 |
Inorganic cadmium increases the frequency of chemically induced chromosome aberrations in cultured mammalian cells.
Topics: 4-Nitroquinoline-1-oxide; Animals; Cadmium; Cells, Cultured; CHO Cells; Chromosome Aberrations; Cricetinae; DNA Damage; DNA Repair; Drug Synergism; G1 Phase; Humans; Mitomycin; Mutagens | 1993 |
[Inhibitory effects of fifteen kinds of Chinese herbal drugs, vegetables and chemicals on SOS response].
Topics: 4-Nitroquinoline-1-oxide; Antimutagenic Agents; Drugs, Chinese Herbal; Escherichia coli; Fluorouracil; Mitomycin; Plant Extracts; SOS Response, Genetics; Vegetables | 1994 |
Treatment with DNA-damaging agents increases expression of polA'-'lacZ gene fusions in Escherichia coli K-12.
Topics: 4-Nitroquinoline-1-oxide; DNA Damage; DNA, Bacterial; Escherichia coli; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Methyl Methanesulfonate; Mitomycin; Promoter Regions, Genetic; Recombinant Fusion Proteins; RNA, Bacterial; RNA, Messenger; SOS Response, Genetics | 1997 |
The ability of the Comet assay to discriminate between genotoxins and cytotoxins.
Topics: 4-Nitroquinoline-1-oxide; Aminacrine; Animals; Cell Extracts; Cell Line; Cell Survival; Cytotoxins; DNA; Electrophoresis, Agar Gel; Ethyl Methanesulfonate; Ethylnitrosourea; Glyoxal; Humans; Hydrogen Peroxide; Mitomycin; Mutagens | 1998 |
Validation of single cell gel assay in human leukocytes with 18 reference compounds.
Topics: 4-Nitroquinoline-1-oxide; Adult; Animals; Ascorbic Acid; Benzaldehydes; Benzo(a)pyrene; Biotransformation; Bleomycin; Chlorophyllides; Cyclophosphamide; DNA Damage; Epoxy Compounds; Female; Formaldehyde; Glucose; Glutaral; Griseofulvin; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Leukocytes; Mannitol; Methylmercury Compounds; Microsomes, Liver; Mitomycin; Mutagenicity Tests; Pyrenes; Rats; Reproducibility of Results; Sodium Azide | 2000 |
Identification of genotoxic stress in human cells by fluorescent monitoring of p53 expression.
Topics: 4-Nitroquinoline-1-oxide; Carcinogenicity Tests; DNA Damage; Doxorubicin; Gene Expression; Genes, Reporter; Green Fluorescent Proteins; Humans; Luminescent Proteins; Methyl Methanesulfonate; Mitomycin; Mutagenicity Tests; Tumor Suppressor Protein p53 | 2001 |
Chromosomal instability in B-lymphoblasotoid cell lines from Werner and Bloom syndrome patients.
Topics: 4-Nitroquinoline-1-oxide; B-Lymphocytes; Bloom Syndrome; Camptothecin; Carcinogens; Case-Control Studies; Cell Division; Cell Line; Chromosome Aberrations; Etoposide; Herpesvirus 4, Human; Humans; Karyotyping; Metaphase; Micronuclei, Chromosome-Defective; Mitomycin; Sister Chromatid Exchange; Werner Syndrome | 2002 |
Investigation of the antimutagenic effects of selected South African medicinal plant extracts.
Topics: 4-Nitroquinoline-1-oxide; Animals; Antimutagenic Agents; Diospyros; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Euphorbiaceae; Gardenia; Humans; Medicine, African Traditional; Methylene Chloride; Micronucleus Tests; Mitomycin; Mutagenicity Tests; Ornithogalum; Plant Extracts; Plant Leaves; Plant Roots; Plants, Medicinal; Prunus; Rhamnose; Salmonella typhimurium; South Africa; Syzygium | 2004 |
Nitric oxide inhibits DNA-adduct excision in nucleotide excision repair.
Topics: 4-Nitroquinoline-1-oxide; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Alkylating Agents; Arsenites; Cell Nucleus; Cisplatin; Comet Assay; DNA; DNA Adducts; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Fibroblasts; Humans; Mitomycin; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Plasmids; Time Factors; Ultraviolet Rays | 2004 |
Studying the synergistic damage effects induced by 1.8 GHz radiofrequency field radiation (RFR) with four chemical mutagens on human lymphocyte DNA using comet assay in vitro.
Topics: 4-Nitroquinoline-1-oxide; Adult; Bleomycin; Comet Assay; DNA; Drug Synergism; Humans; Lymphocytes; Male; Methyl Methanesulfonate; Microwaves; Mitomycin; Mutagens | 2005 |
[Influence of 1.8 GHz microwave on DNA damage induced by 4 chemical mutagens].
Topics: 4-Nitroquinoline-1-oxide; Adult; Bleomycin; Cells, Cultured; Comet Assay; DNA; DNA Damage; Humans; Lymphocytes; Male; Methyl Methanesulfonate; Microwaves; Mitomycin; Mutagens | 2005 |
Cytotoxicity in cultured mammalian cells is a function of the method used to estimate it.
Topics: 2,4-Dinitrophenol; 4-Nitroquinoline-1-oxide; Animals; Benzimidazoles; Carbamates; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colchicine; Leukemia L5178; Mice; Micronucleus Tests; Mitomycin; Mitotic Index; Mutagenicity Tests; Mutagens; Trypan Blue | 2007 |
Modulatory action of 2-deoxy-D-glucose on mitomycin C-and 4-nitroquinoline-1-oxide-induced genotoxicity in Swiss albino mice in vivo.
Topics: 4-Nitroquinoline-1-oxide; Animals; Antineoplastic Agents; Bone Marrow Cells; Deoxyglucose; DNA Damage; Female; Male; Mice; Micronucleus Tests; Mitomycin; Mutagens | 2009 |
Antigenotoxic effects of resveratrol: assessment of in vitro and in vivo response.
Topics: 4-Nitroquinoline-1-oxide; Animals; Antimutagenic Agents; Bone Marrow Cells; Chromosome Aberrations; Chromosomes; DNA Damage; Epoxy Compounds; HL-60 Cells; Humans; Male; Methyl Methanesulfonate; Mice; Micronucleus Tests; Mitomycin; Procarbazine; Quinolones; Resveratrol; Stilbenes | 2016 |
Development of an integrated assay in human TK6 cells to permit comprehensive genotoxicity analysis in vitro.
Topics: 4-Nitroquinoline-1-oxide; Benzo(a)pyrene; Cell Line, Tumor; Cyclophosphamide; Diclofenac; DNA; DNA Damage; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation; Humans; Lymphocytes; Methyl Methanesulfonate; Micronuclei, Chromosome-Defective; Mitomycin; Mutagenesis; Mutagenicity Tests; Mutation; Thymidine Kinase; Vinblastine | 2020 |