Page last updated: 2024-08-22

misonidazole and fluorouracil

misonidazole has been researched along with fluorouracil in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19906 (40.00)18.7374
1990's4 (26.67)18.2507
2000's3 (20.00)29.6817
2010's2 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Levin, VA1
Cai, RM; Ding, L; Jin, XQ; Jin, YZ; Lu, WQ; Shen, ZF; Xu, JF; Xu, LM; Yang, JK1
Bonomi, P; Faber, LP; Reddy, S1
Hasegawa, R1
Allen, J; Edwards, MS; Levin, VA; Ortega, J; Vestnys, P; Wara, WM1
Martin, WM; McDermott, BJ; Murphy, RF; Van den Berg, HW1
Breccia, A; Gattavecchia, E; Tonelli, D1
Tannock, IF1
Maxwell, RJ1
Dachs, GU; Firth, JD; Harris, AL; Patterson, AV; Ratcliffe, PJ; Stratford, IJ; Townsend, KM1
Hicks, RJ; Leong, T; Lim-Joon, D; Loi, S; Mackay, J; Michael, M; Mitchell, P; Mukesh, B; Ngan, SY; Rischin, D; Zalcberg, J1
Haustermans, K; Lee, JA; Loeckx, D; Maes, F; Nuyts, J; Penninckx, F; Roels, S; Slagmolen, P; Stroobants, S1
Chan, K; Fury, M; Humm, J; Lee, N; Ling, CC; Nehmeh, S; Schöder, H1
Ali, S; Lanciano, R; Rose, PG; Stehman, FB; Whitney, CW1
De Bruycker, S; Pauwels, P; Staelens, S; Stroobants, S; Van den Wyngaert, T; Vangestel, C; Wouters, A; Wyffels, L1

Reviews

2 review(s) available for misonidazole and fluorouracil

ArticleYear
Concurrent chemotherapy and thoracic irradiation in non-small cell lung cancer.
    Hematology/oncology clinics of North America, 1990, Volume: 4, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Combined Modality Therapy; Drug Evaluation; Fluorouracil; Humans; Lung Neoplasms; Misonidazole; Neoplasm Metastasis; Prognosis; Radiotherapy; Radiotherapy Dosage; Survival Rate

1990
New techniques in the pharmacokinetic analysis of cancer drugs. III. Nuclear magnetic resonance.
    Cancer surveys, 1993, Volume: 17

    Topics: Antineoplastic Agents; Fluorouracil; Folic Acid; Humans; Magnetic Resonance Spectroscopy; Misonidazole; Neoplasms

1993

Trials

2 trial(s) available for misonidazole and fluorouracil

ArticleYear
Concurrent chemotherapy and thoracic irradiation in non-small cell lung cancer.
    Hematology/oncology clinics of North America, 1990, Volume: 4, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Combined Modality Therapy; Drug Evaluation; Fluorouracil; Humans; Lung Neoplasms; Misonidazole; Neoplasm Metastasis; Prognosis; Radiotherapy; Radiotherapy Dosage; Survival Rate

1990
Oxaliplatin combined with infusional 5-fluorouracil and concomitant radiotherapy in inoperable and metastatic rectal cancer: a phase I trial.
    British journal of cancer, 2005, Feb-28, Volume: 92, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Drug Administration Schedule; Female; Fluorodeoxyglucose F18; Fluorouracil; Humans; Infusions, Intravenous; Male; Middle Aged; Misonidazole; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Positron-Emission Tomography; Radiopharmaceuticals; Radiotherapy Dosage; Radiotherapy, Adjuvant; Rectal Neoplasms; Treatment Outcome

2005

Other Studies

12 other study(ies) available for misonidazole and fluorouracil

ArticleYear
Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:6

    Topics: Animals; Blood-Brain Barrier; Brain; Capillary Permeability; Male; Models, Biological; Molecular Weight; Rats; Rats, Inbred F344; Solubility; Structure-Activity Relationship

1980
Effects of glutathione depletion using buthionine sulphoximine on the cytotoxicity in mammalian cells and human tumor cells in vitro.
    Chinese medical journal, 1992, Volume: 105, Issue:8

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cell Hypoxia; Cisplatin; Drug Synergism; Fluorouracil; Glutathione; Humans; Leukemia, Erythroblastic, Acute; Methionine Sulfoximine; Misonidazole; Stomach Neoplasms; Tumor Cells, Cultured

1992
[The radiosensitizing effects of misonidazole and/or 5FU on C3H mouse mammary carcinoma].
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1985, Sep-25, Volume: 45, Issue:9

    Topics: Animals; Combined Modality Therapy; Female; Fluorouracil; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Misonidazole

1985
5-Fluorouracil and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) followed by hydroxyurea, misonidazole, and irradiation for brain stem gliomas: a pilot study of the Brain Tumor Research Center and the Childrens Cancer Group.
    Neurosurgery, 1984, Volume: 14, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Brain Stem; Child; Child, Preschool; Cobalt Radioisotopes; Combined Modality Therapy; Dose-Response Relationship, Radiation; Female; Fluorouracil; Glioblastoma; Glioma; Humans; Hydroxyurea; Lomustine; Male; Misonidazole; Prognosis; Radioisotope Teletherapy

1984
Pharmacokinetic rationale for the interaction of 5-fluorouracil and misonidazole in humans.
    British journal of cancer, 1983, Volume: 48, Issue:5

    Topics: Adult; Aged; Drug Evaluation; Drug Synergism; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Kinetics; Male; Middle Aged; Misonidazole; Nausea; Nitroimidazoles; Time Factors; Vomiting

1983
Simultaneous determination of some radiosensitizing and chemotherapeutic drugs in plasma by thin-layer chromatography.
    Journal of chromatography, 1983, Jun-10, Volume: 275, Issue:1

    Topics: Antineoplastic Agents; Chromatography, Thin Layer; Cyclophosphamide; Fluorouracil; Humans; Misonidazole; Radiation-Sensitizing Agents

1983
In vivo interaction of anti-cancer drugs with misonidazole or metronidazole: methotrexate, 5-fluorouracil and adriamycin.
    British journal of cancer, 1980, Volume: 42, Issue:6

    Topics: Animals; Body Weight; Doxorubicin; Drug Therapy, Combination; Fibrosarcoma; Fluorouracil; Leukocyte Count; Male; Mammary Neoplasms, Experimental; Methotrexate; Metronidazole; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Sarcoma, Experimental

1980
Targeting gene expression to hypoxic tumor cells.
    Nature medicine, 1997, Volume: 3, Issue:5

    Topics: Animals; Antimetabolites, Antineoplastic; Cell Hypoxia; Cytosine Deaminase; DNA-Binding Proteins; Fibrosarcoma; Flucytosine; Fluorouracil; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Nuclear Proteins; Nucleoside Deaminases; Oxygen; Phosphoglycerate Kinase; Prodrugs; Promoter Regions, Genetic; Recombinant Fusion Proteins; Transcription Factors; Tumor Cells, Cultured

1997
Biological image-guided radiotherapy in rectal cancer: is there a role for FMISO or FLT, next to FDG?
    Acta oncologica (Stockholm, Sweden), 2008, Volume: 47, Issue:7

    Topics: Antimetabolites, Antineoplastic; Cell Hypoxia; Combined Modality Therapy; Dideoxynucleosides; Fluorodeoxyglucose F18; Fluorouracil; Humans; Misonidazole; Positron-Emission Tomography; Radiopharmaceuticals; Rectal Neoplasms; Tomography, X-Ray Computed; Tumor Burden

2008
Prospective trial incorporating pre-/mid-treatment [18F]-misonidazole positron emission tomography for head-and-neck cancer patients undergoing concurrent chemoradiotherapy.
    International journal of radiation oncology, biology, physics, 2009, Sep-01, Volume: 75, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cell Hypoxia; Cisplatin; Combined Modality Therapy; Fluorouracil; Humans; Laryngeal Neoplasms; Middle Aged; Misonidazole; Oropharyngeal Neoplasms; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals; Radiotherapy Dosage; Radiotherapy, Intensity-Modulated; Tomography, X-Ray Computed; Tumor Burden

2009
Outcome of stage IVA cervical cancer patients with disease limited to the pelvis in the era of chemoradiation: a Gynecologic Oncology Group study.
    Gynecologic oncology, 2011, Jun-01, Volume: 121, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Female; Fluorouracil; Humans; Hydroxyurea; Middle Aged; Misonidazole; Neoplasm Staging; Randomized Controlled Trials as Topic; Retrospective Studies; Survival Rate; Treatment Outcome; Uterine Cervical Neoplasms

2011
Baseline [(18)F]FMISO μPET as a Predictive Biomarker for Response to HIF-1α Inhibition Combined with 5-FU Chemotherapy in a Human Colorectal Cancer Xenograft Model.
    Molecular imaging and biology, 2016, Volume: 18, Issue:4

    Topics: Animals; Biomarkers, Tumor; Cell Line, Tumor; Colorectal Neoplasms; Female; Fluorine Radioisotopes; Fluorouracil; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Mice, Nude; Misonidazole; Positron-Emission Tomography; Reproducibility of Results; Xenograft Model Antitumor Assays

2016