Page last updated: 2024-08-22

misonidazole and 1-(4'-hydroxy-2'-butenoxy)methyl-2-nitroimidazole

misonidazole has been researched along with 1-(4'-hydroxy-2'-butenoxy)methyl-2-nitroimidazole in 18 studies

Research

Studies (18)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (44.44)	18.7374
1990's	10 (55.56)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Abe, M; Baba, N; Manabe, T; Sakaguchi, M; Sasai, K; Shibamoto, Y; Takahashi, M	1
Hata, K; Mashiba, H; Matsunaga, K	1
Abe, M; Kitakabu, Y; Sakaguchi, M; Sasai, K; Shibamoto, Y; Streffer, C; Tamulevicius, P	1
Suda, H	1
Mori, T; Murayama, C	3
Mori, T	1
Akaishi, S; Kobari, M; Kodera, T; Matsuno, S; Sakamoto, K	1
Fukuda, H; Hori, H; Inayama, S; Nakajima, T; Onoyama, Y; Sugimoto, K; Tanaka, M	1
Abe, M; Kagiya, T; Mi, FS; Nishimoto, S; Sasai, K; Shibamoto, Y; Takahashi, M	1
Miyamoto, Y; Mori, T; Murayama, C; Sakaguchi, M; Tanaka, N	1
Miyamato, Y	1
Goto, S; Inoue, H; Kato, T; Kim, NS; Mikami, Y; Miyata, K; Okubo, M; Sagitani, H; Umejima, H	2
Streffer, C; Tamulevicius, P	1
Baba, H; Emi, Y; Kusumoto, T; Maehara, Y; Sakaguchi, M; Sakaguchi, Y; Sugimachi, K	1
Ebe, K; Honma, Y; Kuramitsu, T; Matsunaga, N; Miyata, Y; Nakanishi, T; Sakaguchi, M; Suda, H	1

Reviews

2 review(s) available for misonidazole and 1-(4'-hydroxy-2'-butenoxy)methyl-2-nitroimidazole

Article	Year
[Radiosensitizer: hypoxic cell radiosensitizer]. Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:4 Pt 2-2 Topics: Animals; DNA; Dogs; Etanidazole; Hydroxamic Acids; Hydroxylation; Intercalating Agents; Lethal Dose 50; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation Tolerance; Radiation-Sensitizing Agents; Thymine	1989
[Present status of radiation sensitizers--hypoxic cell radiosensitizer]. Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:6 Topics: Animals; Hydroxamic Acids; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Tumor Cells, Cultured	1989

Trials

1 trial(s) available for misonidazole and 1-(4'-hydroxy-2'-butenoxy)methyl-2-nitroimidazole

Article	Year
Pharmacokinetics of intratumoral RK-28, a new hypoxic radiosensitizer. International journal of radiation oncology, biology, physics, 1992, Volume: 24, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Male; Middle Aged; Misonidazole; Pancreatic Neoplasms; Radiation-Sensitizing Agents	1992

Other Studies

15 other study(ies) available for misonidazole and 1-(4'-hydroxy-2'-butenoxy)methyl-2-nitroimidazole

Article	Year
Enhancement of radiosensitizing effect of the nitroimidazole derivative RK28 on the proliferation of MethA tumor cells in combined use with diethyldithiocarbamate. Life sciences, 1991, Volume: 49, Issue:19 Topics: Animals; Cell Division; Cobalt Radioisotopes; Ditiocarb; Drug Synergism; Mice; Mice, Inbred BALB C; Misonidazole; Radiation-Sensitizing Agents; Superoxide Dismutase; Tumor Cells, Cultured	1991
Evaluation of a new 2-nitroimidazole nucleoside analogue, RK-28 as a radiosensitizer for clinical use. International journal of radiation biology, 1991, Volume: 59, Issue:1 Topics: Animals; Cell Hypoxia; Cell Survival; Dogs; Evaluation Studies as Topic; Female; In Vitro Techniques; Male; Mice; Misonidazole; Rabbits; Radiation-Sensitizing Agents; Tissue Distribution	1991
[Intraarterial infusion of hypoxic radiosensitizer RK28 in rabbit VX2 tumor system]. Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1991, Jun-25, Volume: 51, Issue:6 Topics: Animals; Cell Hypoxia; Combined Modality Therapy; Infusions, Intra-Arterial; Male; Misonidazole; Neoplasms, Experimental; Rabbits; Radiation-Sensitizing Agents	1991
[Radiosensitization by hypoxic cell radiosensitizer--present status of radiosensitizer]. Gan no rinsho. Japan journal of cancer clinics, 1990, Volume: 36, Issue:13 Topics: Cell Hypoxia; Etanidazole; Humans; Misonidazole; Nitroimidazoles; Nucleosides; Radiation-Sensitizing Agents	1990
[Development of new hypoxic cell radiosensitizer in Japan]. Gan no rinsho. Japan journal of cancer clinics, 1988, Volume: 34, Issue:13 Topics: Animals; Dogs; Drug Evaluation, Preclinical; Etanidazole; Hydroxamic Acids; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1988
[Experimental study of the intra-operative radiation therapy in pancreatic cancer]. Nihon Geka Gakkai zasshi, 1988, Volume: 89, Issue:8 Topics: Adenocarcinoma; Animals; Cell Division; Combined Modality Therapy; Cricetinae; Intraoperative Care; Mesocricetus; Misonidazole; Pancreatic Neoplasms; Radiation-Sensitizing Agents; Radiotherapy Dosage	1988
[Radiosensitizing effect of the nitroimidazole derivatives RK28 and DNIE on murine tumors]. Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1988, Oct-25, Volume: 48, Issue:10 Topics: Animals; Chemical Phenomena; Chemistry; Drug Evaluation; Lethal Dose 50; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Nitroimidazoles; Rabbits; Radiation-Sensitizing Agents	1988
[Radiosensitizing effects of new 2-nitroimidazole nucleoside analogues (RK-28, RK-29)]. Nihon Gan Chiryo Gakkai shi, 1988, Jan-20, Volume: 23, Issue:1 Topics: Animals; Cell Survival; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Misonidazole; Radiation-Sensitizing Agents; Tumor Cells, Cultured	1988
In vitro and in vivo radiosensitizing effects of 2-nitroimidazole derivatives with sugar component. Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1987, Volume: 163, Issue:6 Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Line; Combined Modality Therapy; Cricetinae; Cricetulus; HeLa Cells; Hypoxia; Mice; Mice, Inbred ICR; Misonidazole; Radiation-Sensitizing Agents; Sarcoma 180	1987
[Radiosensitizing effect of new hypoxic cell radiosensitizer, RK-28 on experimental animal normal tissue and Ehrlich tumor]. Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1985, Aug-25, Volume: 45, Issue:8 Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Survival; Dose-Response Relationship, Drug; Female; Lethal Dose 50; Male; Mice; Misonidazole; Radiation-Sensitizing Agents	1985
Preparation and evaluation of suppositories for RK-28 (a new radiosensitizer) using rabbits. Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:5 Topics: Administration, Oral; Animals; Biological Availability; Chemistry, Pharmaceutical; Injections, Intravenous; Male; Misonidazole; Rabbits; Radiation-Sensitizing Agents; Suppositories	1994
Metabolic studies and neurotoxicity in tumors and brain of mice after hypoxic cell sensitizers. International journal of radiation oncology, biology, physics, 1994, Jun-15, Volume: 29, Issue:3 Topics: Adenosine Triphosphate; Animals; Brain; Etanidazole; Glucose; Male; Mice; Mice, Inbred C57BL; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Nucleosides; Radiation-Sensitizing Agents	1994
Pharmacokinetics of RK-28 (a new radiosensitizer) and pharmaceutical design of a suppository form using rats. Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:1 Topics: Administration, Oral; Administration, Rectal; Animals; Biological Availability; Dosage Forms; Dose-Response Relationship, Drug; Drug Design; Drug Stability; Half-Life; Injections, Intravenous; Male; Misonidazole; Radiation-Sensitizing Agents; Rats; Rats, Wistar; Suppositories	1994
Effect of hyperthermia on the activity of 1-[(4'-hydroxy-2'-butenoxy)methyl]-2-nitroimidazole, which is cytotoxic to hypoxic cells. Cancer chemotherapy and pharmacology, 1993, Volume: 31, Issue:6 Topics: Animals; Cell Hypoxia; Cell Survival; Combined Modality Therapy; Dose-Response Relationship, Drug; Female; Hyperthermia, Induced; Mammary Neoplasms, Experimental; Mice; Misonidazole; Radiation-Sensitizing Agents; Time Factors; Tumor Cells, Cultured	1993
Evaluation of the radiosensitizing effects of RK28 intravenous, intraarterial, and intratumoral injections on the rabbit VX2 tumor system. International journal of radiation oncology, biology, physics, 1996, Dec-01, Volume: 36, Issue:5 Topics: Animals; Carcinoma, Squamous Cell; Injections, Intra-Arterial; Injections, Intravenous; Male; Misonidazole; Neoplasms, Experimental; Rabbits; Radiation-Sensitizing Agents	1996