mirtazapine and trazodone

mirtazapine has been researched along with trazodone in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.45)18.2507
2000's11 (37.93)29.6817
2010's14 (48.28)24.3611
2020's3 (10.34)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Ahman, M; Holmén, AG; Wan, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
de Wilde, J; Dierick, M; Evrard, JL; Mendlewicz, J; van Moffaert, M; Vereecken, A; Wilmotte, J1
Bateman, DN; Chick, J; Good, AM; Kelly, CA; Masterton, G1
Fava, M1
Almási, J; Rihmer, Z1
Albertazzi, P1
Tuya, AC1
Hassan, M; Marcus, SC; Olfson, M1
Dubois, J; Vanrullen, R1
Wichniak, A; Wierzbicka, A1
Clark, MS; Jamieson, B; Smith, PO1
Aleksic, B; Iidaka, T; Iwamoto, K; Katayama, H; Kawano, N; Kohmura, K; Noda, A; Noda, Y; Ozaki, N; Sasada, K1
Aleksic, B; Ebe, K; Iwamoto, K; Kawano, N; Kohmura, K; Noda, Y; Ozaki, N; Sasada, K; Yamamoto, M1
Khouzam, HR1
Alessi-Severini, S; Bolton, J; Chateau, D; Enns, MW; Leong, C; Prior, HJ; Sareen, J1
Greenspan, SL; Hanlon, JT; Kotlarczyk, MP; Naples, JG; Perera, S1
Chen, HM; Chen, KJ; Chen, VC; Hsieh, MC; Lee, Y; Lee, YC; Lu, ML; McIntyre, RS; Yang, YH1
Pick, CG; Schreiber, S1
Benz, P; Farkas, A; Ryan, K; Theobald, J; Zosel, A1
Keidan, L; Pick, CG; Schreiber, S1

Reviews

6 review(s) available for mirtazapine and trazodone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Daytime sleepiness and insomnia as correlates of depression.
    The Journal of clinical psychiatry, 2004, Volume: 65 Suppl 16

    Topics: Antidepressive Agents; Benzhydryl Compounds; Bupropion; Comorbidity; Depressive Disorder; Disorders of Excessive Somnolence; Drug Therapy, Combination; Humans; Mianserin; Mirtazapine; Modafinil; Monoamine Oxidase Inhibitors; Secondary Prevention; Selective Serotonin Reuptake Inhibitors; Sleep; Sleep Initiation and Maintenance Disorders; Trazodone

2004
[Review of antidepressants from the TCAs to the third generation drugs].
    Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2004, Volume: 6, Issue:4

    Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bupropion; Cyclohexanols; Cyclopropanes; Depressive Disorder, Major; Drug Combinations; Duloxetine Hydrochloride; Humans; Mianserin; Milnacipran; Mirtazapine; Monoamine Oxidase Inhibitors; Morpholines; Piperazines; Pyrimidines; Reboxetine; Selective Serotonin Reuptake Inhibitors; Thiophenes; Trazodone; Triazoles; Venlafaxine Hydrochloride

2004
Noradrenergic and serotonergic modulation to treat vasomotor symptoms.
    The journal of the British Menopause Society, 2006, Volume: 12, Issue:1

    Topics: Citalopram; Cyclohexanols; Female; Fluoxetine; Hot Flashes; Humans; Menopause; Mianserin; Mirtazapine; Paroxetine; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Trazodone; Venlafaxine Hydrochloride

2006
[The effects of antidepressants on sleep in depressed patients with particular reference to trazodone in comparison to agomelatine, amitriptyline, doxepin, mianserine and mirtazapine].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2011, Volume: 31, Issue:181

    Topics: Amitriptyline; Antidepressive Agents; Depression; Doxepin; Humans; Mianserin; Mirtazapine; Sleep; Sleep Initiation and Maintenance Disorders; Sleep, REM; Trazodone

2011
Psychopharmacology of chronic pain: a focus on antidepressants and atypical antipsychotics.
    Postgraduate medicine, 2016, Volume: 128, Issue:3

    Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Bupropion; Chronic Pain; Humans; Mianserin; Mirtazapine; Olanzapine; Piperazines; Quetiapine Fumarate; Risperidone; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Thiazoles; Trazodone; Triazoles

2016

Trials

3 trial(s) available for mirtazapine and trazodone

ArticleYear
Mirtazapine is more effective than trazodone: a double-blind controlled study in hospitalized patients with major depression.
    International clinical psychopharmacology, 1995, Volume: 10, Issue:1

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Psychiatric Status Rating Scales; Trazodone

1995
Effects of sedative antidepressants on prefrontal cortex activity during verbal fluency task in healthy subjects: a near-infrared spectroscopy study.
    Psychopharmacology, 2013, Volume: 226, Issue:1

    Topics: Adult; Analysis of Variance; Antidepressive Agents; Cross-Over Studies; Double-Blind Method; Functional Neuroimaging; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Oxyhemoglobins; Prefrontal Cortex; Sleep; Spectroscopy, Near-Infrared; Speech Production Measurement; Task Performance and Analysis; Trazodone

2013
Effects of repeated dosing with mirtazapine, trazodone, or placebo on driving performance and cognitive function in healthy volunteers.
    Human psychopharmacology, 2013, Volume: 28, Issue:3

    Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Automobile Driving; Cognition; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Sleep Stages; Trazodone

2013

Other Studies

20 other study(ies) available for mirtazapine and trazodone

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Are selective serotonin re-uptake inhibitors associated with an increased risk of self-harm by antidepressant overdose?
    European journal of clinical pharmacology, 2004, Volume: 60, Issue:3

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Citalopram; Cyclohexanols; Doxepin; Drug Overdose; Drug Prescriptions; Emergency Service, Hospital; Female; Fluoxetine; Humans; Imipramine; Information Services; Male; Mianserin; Mirtazapine; Paroxetine; Patient Admission; Patient Readmission; Poison Control Centers; Retrospective Studies; Risk Assessment; Scotland; Selective Serotonin Reuptake Inhibitors; Self-Injurious Behavior; Sertraline; Trazodone; Venlafaxine Hydrochloride

2004
The management of insomnia in the older adult.
    Medicine and health, Rhode Island, 2007, Volume: 90, Issue:6

    Topics: Aged; Aged, 80 and over; Anti-Anxiety Agents; Antidepressive Agents; Baths; Exercise; Humans; Hypnotics and Sedatives; Indenes; Male; Mianserin; Mirtazapine; Pyridines; Relaxation Therapy; Sleep Initiation and Maintenance Disorders; Trazodone; Zolpidem

2007
Antidepressant switching among adherent patients treated for depression.
    Psychiatric services (Washington, D.C.), 2009, Volume: 60, Issue:5

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Antidepressive Agents, Tricyclic; Cyclohexanols; Depressive Disorder; Depressive Disorder, Major; Drug Administration Schedule; Humans; Mianserin; Middle Aged; Mirtazapine; Patient Compliance; Sertraline; Trazodone; Venlafaxine Hydrochloride; Young Adult

2009
Visual trails: do the doors of perception open periodically?
    PLoS biology, 2011, Volume: 9, Issue:5

    Topics: Anticonvulsants; Antidepressive Agents; Female; Fructose; Hallucinogens; Humans; Lysergic Acid Diethylamide; Male; Mianserin; Middle Aged; Mirtazapine; Perceptual Disorders; Piperazines; Topiramate; Trazodone; Triazoles; Visual Perception

2011
FPIN's clinical inquiries: Antidepressants for the treatment of insomnia in patients with depression.
    American family physician, 2011, Nov-01, Volume: 84, Issue:9

    Topics: Amitriptyline; Antidepressive Agents; Antidepressive Agents, Tricyclic; Depression; Dose-Response Relationship, Drug; Doxepin; Evidence-Based Medicine; Humans; Mianserin; Mirtazapine; Practice Guidelines as Topic; Sleep Initiation and Maintenance Disorders; Trazodone; Trimipramine

2011
New antidepressant use in older adults: a Canadian population-based study (1997-2013).
    Aging & mental health, 2017, Volume: 21, Issue:7

    Topics: Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Cross-Sectional Studies; Drug Prescriptions; Drug Utilization; Female; Humans; Male; Manitoba; Mianserin; Middle Aged; Mirtazapine; Retrospective Studies; Trazodone; Venlafaxine Hydrochloride

2017
Non-tricyclic and Non-selective Serotonin Reuptake Inhibitor Antidepressants and Recurrent Falls in Frail Older Women.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2016, Volume: 24, Issue:12

    Topics: Accidental Falls; Aged, 80 and over; Antidepressive Agents; Bupropion; Female; Frail Elderly; Humans; Mianserin; Mirtazapine; Recurrence; Risk Factors; Selective Serotonin Reuptake Inhibitors; Trazodone

2016
Antidepressants Reduced Risk of Mortality in Patients With Diabetes Mellitus: A Population-Based Cohort Study in Taiwan.
    The Journal of clinical endocrinology and metabolism, 2019, 10-01, Volume: 104, Issue:10

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Antidepressive Agents, Tricyclic; Cohort Studies; Comorbidity; Depressive Disorder; Depressive Disorder, Major; Diabetes Mellitus; Dopamine Uptake Inhibitors; Dysthymic Disorder; Female; Humans; Male; Middle Aged; Mirtazapine; Monoamine Oxidase Inhibitors; Mortality; Proportional Hazards Models; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Taiwan; Trazodone; Young Adult

2019
Trazodone and mirtazapine: A possible opioid involvement in their use (at low dose) for sleep?
    Medical hypotheses, 2020, Volume: 136

    Topics: Analgesics; Analgesics, Opioid; Animals; Antidepressive Agents; Depression; Disease Models, Animal; Male; Mice; Mice, Inbred ICR; Mirtazapine; Naloxone; Receptors, Opioid; Serotonin; Sleep; Sleep Wake Disorders; Trazodone; Zolpidem

2020
QTc Prolongation in Poison Center Exposures to CredibleMeds List of Substances with "Known Risk of Torsades de Pointes".
    Cardiovascular toxicology, 2022, Volume: 22, Issue:9

    Topics: Amitriptyline; Arrhythmias, Cardiac; Diphenhydramine; Electrocardiography; Flecainide; Humans; Long QT Syndrome; Methadone; Mirtazapine; Poison Control Centers; Retrospective Studies; Risk Factors; Tachycardia, Ventricular; Torsades de Pointes; Trazodone; Ventricular Fibrillation

2022
Treatment-Resistant Depression (TRD): Is the Opioid System Involved?
    International journal of molecular sciences, 2023, Jul-06, Volume: 24, Issue:13

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Depression; Dose-Response Relationship, Drug; Fluoxetine; Fluvoxamine; Mianserin; Mice; Mirtazapine; Moclobemide; Naloxone; Reboxetine; Trazodone; Venlafaxine Hydrochloride

2023