mirtazapine and morphine

mirtazapine has been researched along with morphine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (60.00)29.6817
2010's6 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Chen, CC; Hsu, YW; Hung, YC; Ko, YP; Lao, HC; Lin, CS1
Hu, M; Kang, L; Li, B; Li, J; Wang, D; Zhang, P1
Chang, FL; Ho, ST; Huang, ST; Lee, CH; Sheen, MJ; Tsung, YC1
Cahill, CM; Jhamandas, K; Milne, B; Sutak, M1
Chang, FL; Ho, ST; Sheen, MJ1
Graves, SM; Napier, TC; Persons, AL; Riddle, JL1

Reviews

1 review(s) available for mirtazapine and morphine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

3 trial(s) available for mirtazapine and morphine

ArticleYear
Premedication with mirtazapine reduces preoperative anxiety and postoperative nausea and vomiting.
    Anesthesia and analgesia, 2008, Volume: 106, Issue:1

    Topics: Adult; Analgesics, Opioid; Anti-Anxiety Agents; Antiemetics; Anxiety; Double-Blind Method; Female; Gynecologic Surgical Procedures; Humans; Mianserin; Middle Aged; Mirtazapine; Morphine; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Preanesthetic Medication; Serotonin Antagonists; Time Factors; Treatment Outcome

2008
Prophylactic mirtazapine reduces intrathecal morphine-induced pruritus.
    British journal of anaesthesia, 2008, Volume: 101, Issue:5

    Topics: Adult; Analgesics, Opioid; Anesthesia, Spinal; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Injections, Spinal; Lower Extremity; Male; Mianserin; Mirtazapine; Morphine; Preanesthetic Medication; Prospective Studies; Pruritus; Serotonin Antagonists; Severity of Illness Index; Treatment Outcome

2008
Efficacy of mirtazapine in preventing intrathecal morphine-induced nausea and vomiting after orthopaedic surgery*.
    Anaesthesia, 2010, Volume: 65, Issue:12

    Topics: Adult; Analgesics, Opioid; Anesthesia, Spinal; Antiemetics; Double-Blind Method; Humans; Lower Extremity; Mianserin; Middle Aged; Mirtazapine; Morphine; Orthopedic Procedures; Pain, Postoperative; Postoperative Nausea and Vomiting; Postoperative Period; Preanesthetic Medication; Treatment Outcome; Young Adult

2010

Other Studies

11 other study(ies) available for mirtazapine and morphine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Mirtazapine, a noradrenergic and specific serotonergic antidepressant, attenuates morphine dependence and withdrawal in Sprague-Dawley rats.
    The American journal of drug and alcohol abuse, 2008, Volume: 34, Issue:5

    Topics: Animals; Antidepressive Agents, Tricyclic; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Administration Schedule; Male; Mianserin; Mirtazapine; Morphine; Morphine Dependence; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Substance Withdrawal Syndrome

2008
Low doses of alpha 2-adrenoceptor antagonists augment spinal morphine analgesia and inhibit development of acute and chronic tolerance.
    British journal of pharmacology, 2008, Volume: 155, Issue:8

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Idazoxan; Imidazoles; Male; Mianserin; Mirtazapine; Morphine; Rats; Rats, Sprague-Dawley; Spine; Yohimbine

2008
The atypical antidepressant mirtazapine attenuates expression of morphine-induced place preference and motor sensitization.
    Brain research, 2012, Sep-07, Volume: 1472

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Conditioning, Operant; Cues; Disease Models, Animal; Male; Mianserin; Mirtazapine; Morphine; Morphine Dependence; Motor Activity; Rats; Rats, Sprague-Dawley; Reward

2012