minoxidil and methotrexate

minoxidil has been researched along with methotrexate in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (18.75)29.6817
2010's12 (75.00)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Alkhalifah, A; Alsantali, A; McElwee, KJ; Shapiro, J; Wang, E1
Shapiro, J1
Fabi, SG; Zaleski-Larsen, LA1
Avila, L; Brinster, N; Christiano, AM; Lo Sicco, K; Shapiro, J; Strazzulla, LC; Wang, EHC1
Atallah, RB; Eldahshan, RM; Toma, DM1

Reviews

5 review(s) available for minoxidil and methotrexate

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Alopecia areata update: part II. Treatment.
    Journal of the American Academy of Dermatology, 2010, Volume: 62, Issue:2

    Topics: Administration, Topical; Adrenal Cortex Hormones; Adult; Alopecia Areata; Animals; Child; Cyclopropanes; Cyclosporine; Hair; Haptens; Humans; Immunotherapy; Injections, Intralesional; Laser Therapy; Methotrexate; Minoxidil; Photochemotherapy; Randomized Controlled Trials as Topic; Rats; Recurrence; Research Design; Social Support; Sulfasalazine; Treatment Outcome; Triamcinolone Acetonide

2010
Current treatment of alopecia areata.
    The journal of investigative dermatology. Symposium proceedings, 2013, Volume: 16, Issue:1

    Topics: Administration, Cutaneous; Adrenal Cortex Hormones; Alopecia Areata; Anthralin; Cyclobutanes; Cyclopropanes; Cyclosporine; Dermatologic Agents; Humans; Immunosuppressive Agents; Injections, Intralesional; Methotrexate; Minoxidil; PUVA Therapy; Self-Help Groups

2013
Laser-Assisted Drug Delivery.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2016, Volume: 42, Issue:8

    Topics: Administration, Cutaneous; Adrenergic beta-Antagonists; Aminolevulinic Acid; Aminoquinolines; Analgesics; Antibodies; Antineoplastic Agents; Ascorbic Acid; Cyclopropanes; Dermatologic Agents; Drug Delivery Systems; Fluorouracil; Humans; Imiquimod; Immunotherapy; Laser Therapy; Methotrexate; Minoxidil; Permeability; Photosensitizing Agents; Polyesters; RNA, Small Interfering; Skin; Timolol; Vaccines

2016
Alopecia areata: An appraisal of new treatment approaches and overview of current therapies.
    Journal of the American Academy of Dermatology, 2018, Volume: 78, Issue:1

    Topics: Administration, Oral; Administration, Topical; Adrenal Cortex Hormones; Alopecia Areata; Dermatologic Agents; Education, Medical, Continuing; Female; Humans; Immunotherapy; Injections, Intralesional; Male; Methotrexate; Minoxidil; Quality of Life; Risk Assessment; Severity of Illness Index; Treatment Outcome

2018

Trials

1 trial(s) available for minoxidil and methotrexate

ArticleYear
Comparative study between topical methotrexate 1% gel and minoxidil 5% gel in the treatment of localized alopecia areata.
    Dermatologic therapy, 2022, Volume: 35, Issue:9

    Topics: Administration, Topical; Alopecia; Alopecia Areata; Gels; Humans; Methotrexate; Minoxidil; Treatment Outcome

2022

Other Studies

10 other study(ies) available for minoxidil and methotrexate

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013