minocycline and titanium-dioxide

Minocycline has been widely used in central nervous system disease. However, the effect of minocycline on the repairing of nerve fibers around dental implants had not been previously investigated. The aim of the present study was to evaluate the possibility of using minocycline for the repairing of nerve fibers around dental implants by investigating the effect of minocycline on the proliferation of Schwann cells and secretion of neurotrophic factors nerve growth factor and glial cell line-derived neurotrophic factor in vitro.. The results suggested that the surface functionalization of TiO

Topics: Biocompatible Materials; Cell Line; Cell Proliferation; Cell Survival; Gene Expression Regulation; Minocycline; Nanotubes; Schwann Cells; Surface Properties; Titanium