minocycline has been researched along with lomefloxacin* in 3 studies
3 other study(ies) available for minocycline and lomefloxacin
Article | Year |
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In vitro and in vivo activities of fluoroquinolones against Aeromonas hydrophila.
Aeromonas hydrophila, an uncommon human pathogen, can cause invasive infections in immunocompromised individuals. As the fluoroquinolones have been shown to be active in vitro against mesophilic aeromonads and clinical experience with the use of fluoroquinolones to treat aeromonads infections is limited, the antimicrobial activities of five selected drugs (ciprofloxacin, gatifloxacin, levofloxacin, lomefloxacin, and moxifloxacin) against A. hydrophila were studied in vitro and in mice. The MICs of the fluoroquinolones (except lomefloxacin), cefotaxime, and minocycline for 90% of 64 clinical isolates of A. hydrophila tested by the agar dilution method were Topics: Aeromonas hydrophila; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Cefotaxime; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacterial Infections; Humans; In Vitro Techniques; Levofloxacin; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Minocycline; Moxifloxacin; Ofloxacin; Quinolines; Quinolones | 2003 |
Minimal inhibitory concentrations of lomefloxacin and minocycline against drug-sensitive and drug-resistant isolates of M. tuberculosis compared on L-J and 7H11 media.
The in vitro activity of lomefloxacin and minocycline was tested against 46 strains of M. tuberculosis resistant to streptomycin (S), isoniazid (H) and rifampin (R) or SHR and 51 strains sensitive to SHR by the minimal inhibitory concentration (MIC) method on two different media, namely, Lowenstein-Jensen (L-J) and Middlebrook 7H11. The results of the study showed that, irrespective of the medium used, minocycline had little activity against the strains tested and the MIC was > 64 micrograms/ml. The MIC of lomefloxacin in 7H11 medium ranged from 2 to 16 micrograms/ml. There were highly significant differences in the MICs of lomefloxacin in L-J compared with 7H11. The results suggest that the activity of lomefloxacin against M. tuberculosis merits further study. Topics: Anti-Infective Agents; Antitubercular Agents; Culture Media; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Minocycline; Mycobacterium tuberculosis; Quinolones | 1997 |
In vitro activities of ofloxacin and four other new quinoline-carboxylic acids against Chlamydia trachomatis.
The in vitro activities of five new quinoline-carboxylic acids against 2 reference strains and 45 clinical isolates of Chlamydia trachomatis of genital origin were compared with the activities of minocycline and doxycycline. Ofloxacin was the third most active agent (after the two tetracyclines), followed by ciprofloxacin, NY-198, and AM-833. Topics: Anti-Infective Agents; Chlamydia trachomatis; Ciprofloxacin; Doxycycline; Fleroxacin; Fluoroquinolones; Minocycline; Norfloxacin; Ofloxacin; Quinolones | 1988 |