Page last updated: 2024-08-25

minaxolone and pregnanolone

minaxolone has been researched along with pregnanolone in 40 studies

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	32 (80.00)	18.7374
1990's	6 (15.00)	18.2507
2000's	2 (5.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Anderson, A; Boyd, AC; Byford, A; Campbell, AC; Gemmell, DK; Hamilton, NM; Hill, DR; Hill-Venning, C; Lambert, JJ; Maidment, MS; Marshall, RJ; May, V; Peters, JA; Rees, DC; Stevenson, D; Sundaram, H	1
Aveling, W; Campbell, D; Chang, H; Cooper, GM; Fitch, W; Prys-Roberts, C; Savege, TM; Sear, JW; Simpson, P; Waters, A	1
Clarke, RS; Dundee, JW; McNeill, HG	1
Dundee, JW	2
Dye, J; Prys-Roberts, C; Sear, JW	1
Briggs, LP; Clarke, RS; Dundee, JW; McNeill, HG	2
Carapetis, RJ; Mather, LE; McLean, CF; Runciman, WB; Upton, RN	1
Desmonts, JM	1
Prys-Roberts, C; Sear, JW	2
Dye, A; Prys-Roberts, C; Sear, JW	1
Sear, JW	3
Bretz, C; Doenicke, A; Haegler, H; Kugler, J; Suttmann, H; Wörschhauser, J	1
Clarke, RS	1
Prys-Roberts, C	1
Meloche, R; Prys-Roberts, C	1
Dunn, GL; Gupta, RN; Kumana, CR; McChesney, J; Morison, DH; Pine, W	1
Omand, WD; Roth, SH	1
Hull, CJ	1
Curnow, JS; Dye, J; Gray, AJ; Prys-Roberts, C; Sear, JW; Walsh, EM	1
Gourlay, GK; Mather, LE; Parkin, KS; Roberts, JG	1
Hope, CE	1
Cousins, MJ; Gourlay, GK; Mather, LE; Roberts, JG; Seow, LT	3
Chapman, JM; Cooper, GM; Gray, AJ; Prys-Roberts, C; Sear, JW; Simpson, PJ	1
Dunn, GL; McChesney, J; Morison, DH; Pine, W	1
Cooper, GM; Prys-Roberts, C; Sear, JW; Simpson, PJ; Williams, NB	1
Lumley, J; Morgan, M; Punchihewa, VG; Whitwam, JG	1
Harrison, GG; Morrell, DF	1
Lumley, J; Morgan, M; Puchihewa, VG; Whitwam, JG	1
Evans, DF; Foster, GE; Healy, TE; Syed, A	1
Kumar, V; Kumar, VL; Malhotra, J	1
Ford, E; Hagan, RM; Marshall, FH; Mullings, J; Oakley, NR; Stratton, SC; Worton, SP	1
Belelli, D; Lambert, JJ; Ling, AT; Peters, JA; Weir, CJ; Wildsmith, JA	1
Belelli, D; Dempster, J; Gentet, LJ; Mitchell, EA	1

Reviews

4 review(s) available for minaxolone and pregnanolone

Article	Year
General kinetic and dynamic principles and their application to continuous infusion anaesthesia. Anaesthesia, 1983, Volume: 38 Suppl Topics: Adult; Alfaxalone Alfadolone Mixture; Anesthesia, Intravenous; Anesthetics; Animals; Etomidate; Humans; Hypnotics and Sedatives; Infusions, Parenteral; Kinetics; Mathematics; Methohexital; Middle Aged; Models, Biological; Phenols; Pregnanolone; Propofol; Rats; Thiopental	1983
Management of anesthesia in patients with hypertension or ischemic heart disease. International anesthesiology clinics, 1980,Winter, Volume: 18, Issue:4 Topics: Alfaxalone Alfadolone Mixture; Analgesics; Anesthesia; Anesthesia, Conduction; Anesthesia, Local; Coronary Disease; Emergencies; Fentanyl; Fluid Therapy; Humans; Hypertension; Monitoring, Physiologic; Morphine; Narcotics; Postoperative Care; Pregnanolone; Premedication; Surgical Procedures, Operative	1980
Anaesthetic steroids--a review. Indian journal of medical sciences, 1993, Volume: 47, Issue:4 Topics: Alfaxalone Alfadolone Mixture; Anesthetics; Animals; Pregnanediones; Pregnanolone; Steroids	1993
Steroid anesthetics: old compounds, new drugs. Journal of clinical anesthesia, 1996, Volume: 8, Issue:3 Suppl Topics: Alfaxalone Alfadolone Mixture; Anesthetics; Chloride Channels; Humans; Hypnotics and Sedatives; Pregnanolone; Receptors, GABA-A; Steroids	1996

Trials

3 trial(s) available for minaxolone and pregnanolone

Article	Year
Early clinical evaluation of minaxolone: a new intravenous steroid anaesthetic agent. Lancet (London, England), 1979, Jul-14, Volume: 2, Issue:8133 Topics: Adult; Aged; Anesthesia, Intravenous; Anesthetics; Blood Pressure; Citrates; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Male; Middle Aged; Minor Surgical Procedures; Pregnanes; Pregnanolone; Pulse; Respiration; Solubility	1979
Hepatic function after anaesthesia for major vascular reconstructive surgery. British journal of anaesthesia, 1983, Volume: 55, Issue:7 Topics: Aged; Alfaxalone Alfadolone Mixture; Anesthesia, General; Aspartate Aminotransferases; Bilirubin; gamma-Glutamyltransferase; Halothane; Humans; L-Lactate Dehydrogenase; Liver; Middle Aged; Ornithine Carbamoyltransferase; Phenols; Pregnanolone; Propofol; Vascular Surgical Procedures	1983
Initial experience with Minaxolone. A water-soluble steroid intravenous anaesthetic agent. Anaesthesia, 1980, Volume: 35, Issue:2 Topics: Adult; Anesthesia, Intravenous; Atropine; Blood Pressure; Female; Fentanyl; Humans; Nitrous Oxide; Pregnanes; Pregnanolone; Pulse	1980

Other Studies

33 other study(ies) available for minaxolone and pregnanolone

Article	Year
Anesthetic activity of novel water-soluble 2 beta-morpholinyl steroids and their modulatory effects at GABAA receptors. Journal of medicinal chemistry, 1997, May-23, Volume: 40, Issue:11 Topics: Anesthesia; Anesthetics; Animals; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cell Membrane; Chromaffin System; Electric Conductivity; Electrophysiology; Male; Mice; Molecular Structure; Morpholines; Pregnanediones; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Solubility; Structure-Activity Relationship; Water	1997
Minaxolone: a new water-soluble steroid anaesthetic. Lancet (London, England), 1979, Jul-14, Volume: 2, Issue:8133 Topics: Anesthesia, Intravenous; Anesthetics; Dose-Response Relationship, Drug; Drug Evaluation; Female; Humans; Male; Minor Surgical Procedures; Pregnanes; Pregnanolone; Propanidid; Solubility; Thiopental	1979
New i.v. anaesthetics. British journal of anaesthesia, 1979, Volume: 51, Issue:7 Topics: Anesthesia, Intravenous; Anesthetics; Animals; Benzodiazepines; Etomidate; Humans; Kinetics; Midazolam; Phenols; Pregnanolone; Propofol	1979
Cardiovascular studies during induction with minaxolone. Acta anaesthesiologica Belgica, 1979, Volume: 30 Suppl Topics: Anesthesia, Intravenous; Anesthetics; Blood Gas Analysis; Blood Pressure; Cardiac Output; Heart Rate; Hemodynamics; Humans; Hypertension; Pregnanes; Pregnanolone; Time Factors; Vascular Resistance	1979
The influence of dosage and premedication on induction of anesthesia with minaxolone. Acta anaesthesiologica Belgica, 1979, Volume: 30 Suppl Topics: Adult; Anesthesia, Intravenous; Anesthetics; Blood Pressure; Diazepam; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Movement; Narcotics; Preanesthetic Medication; Pregnanes; Pregnanolone; Respiration	1979
Uptake and elution of chlormethiazole, meperidine, and minaxolone in the hindquarters of sheep: implications for clearance calculations. Journal of pharmaceutical sciences, 1991, Volume: 80, Issue:2 Topics: Anesthetics; Animals; Chlormethiazole; Hindlimb; Infusions, Intravenous; Meperidine; Metabolic Clearance Rate; Models, Biological; Pregnanolone; Sheep	1991
[Intravenous anesthetics: what future?]. Annales francaises d'anesthesie et de reanimation, 1985, Volume: 4, Issue:1 Topics: Alfaxalone Alfadolone Mixture; Anesthesia, Intravenous; Animals; Benzodiazepines; Etomidate; Humans; Midazolam; Phenols; Polyethylene Glycols; Pregnanolone; Propofol	1985
Alphadione and minaxolone pharmacokinetics. Annales de l'anesthesiologie francaise, 1981, Volume: 22, Issue:2 Topics: Alfaxalone Alfadolone Mixture; Anesthesia, Intravenous; Anesthetics; Humans; Kinetics; Pregnanes; Pregnanolone	1981
[Perspective on future developments of intravenous hypnotic agents]. Klinische Anasthesiologie und Intensivtherapie, 1981, Volume: 23 Topics: Anesthesia, Intravenous; Chemical Phenomena; Chemistry; Etomidate; Humans; Hypnotics and Sedatives; Phenols; Pregnanolone; Propofol	1981
Comparative merits of intravenous anesthetic agents for outpatient surgery. International anesthesiology clinics, 1982,Spring, Volume: 20, Issue:1 Topics: Alfaxalone Alfadolone Mixture; Ambulatory Surgical Procedures; Anesthesia, Intravenous; Anesthetics; Drug Hypersensitivity; Etomidate; Humans; Ketamine; Methohexital; Phenols; Pregnanolone; Propanidid; Propofol; Thiopental	1982
Cardiovascular effects of continuous intravenous anaesthesia compared with those of inhalational anaesthesia. Acta anaesthesiologica Scandinavica. Supplementum, 1982, Volume: 75 Topics: Adult; Alfaxalone Alfadolone Mixture; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics; Cardiovascular System; Etomidate; Halothane; Humans; Methohexital; Middle Aged; Nitrous Oxide; Phenols; Pregnanolone; Propofol	1982
The pharmacokinetics and pharmacodynamics of minaxolone. Journal of clinical pharmacology, 1982, Volume: 22, Issue:7 Topics: Adult; Anesthesia; Anesthetics; Female; Genital Diseases, Female; Hemodynamics; Humans; Kinetics; Pregnanes; Pregnanolone	1982
Pregnane steroid anesthetics exhibit selective action on the firing activity of an isolated neuron. Proceedings of the Western Pharmacology Society, 1982, Volume: 25 Topics: Animals; Astacoidea; In Vitro Techniques; Muscle Contraction; Neurons; Pregnanediones; Pregnanes; Pregnanolone	1982
Minaxolone and alphaxalone. British journal of anaesthesia, 1981, Volume: 53, Issue:4 Topics: Alfaxalone Alfadolone Mixture; Humans; Pregnanes; Pregnanolone	1981
Infusions of minaxolone to supplement nitrous oxide-oxygen anaesthesia. A comparison with althesin. British journal of anaesthesia, 1981, Volume: 53, Issue:4 Topics: Adult; Aged; Alfaxalone Alfadolone Mixture; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics; Blood Gas Analysis; Electroencephalography; Female; Hemodynamics; Humans; Infusions, Parenteral; Kinetics; Male; Middle Aged; Nitrous Oxide; Oxygen; Pregnanes; Pregnanolone; Respiration	1981
Pharmacodynamics of minaxolone, a new steroidal anesthetic. The Journal of pharmacology and experimental therapeutics, 1981, Volume: 217, Issue:2 Topics: Anesthetics; Animals; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Hemodynamics; Infusions, Parenteral; Pregnanes; Pregnanolone; Reflex; Respiration; Sheep	1981
Clinical trial--the minaxolone story. Canadian Anaesthetists' Society journal, 1981, Volume: 28, Issue:1 Topics: Anesthetics; Animals; Clinical Trials as Topic; Drug Evaluation; Humans; Pregnanes; Pregnanolone	1981
Development of a model for integrated pharmacokinetic and pharmacodynamic studies of intravenous anaesthetic agents: applications to minaxolone. European journal of clinical pharmacology, 1981, Volume: 19, Issue:5 Topics: Adult; Anesthetics; Female; Heart Rate; Humans; Infusions, Parenteral; Kinetics; Male; Metabolic Clearance Rate; Models, Biological; Pregnanes; Pregnanolone; Respiration	1981
Safety record: intravenous anesthetic. Anaesthesia, 1981, Volume: 36, Issue:6 Topics: Anesthesia, Intravenous; Anesthetics; Humans; Pregnanolone; Safety	1981
Minaxolone, clinical effects and pharmacokinetics. Subanaesthetic infusion regimen. Anaesthesia, 1981, Volume: 36, Issue:6 Topics: Adult; Anesthetics; Female; Humans; Infusions, Parenteral; Kinetics; Male; Metabolic Clearance Rate; Pregnanes; Pregnanolone	1981
Minaxolone: an evaluation with and without premedication. Anaesthesia, 1981, Volume: 36, Issue:6 Topics: Adult; Akathisia, Drug-Induced; Anesthesia, Intravenous; Anesthetics; Female; Genital Diseases, Female; Humans; Preanesthetic Medication; Pregnanes; Pregnanolone; Respiration Disorders	1981
Studies on premedication and ventilatory responses to minaxolone. Acta anaesthesiologica Belgica, 1981, Volume: 32, Issue:2 Topics: Adult; Anesthetics; Atropine; Diazepam; Female; Humans; Male; Morphine; Nitrous Oxide; Oxygen; Preanesthetic Medication; Pregnanes; Pregnanolone; Respiration; Time Factors	1981
Minaxolone. Canadian Anaesthetists' Society journal, 1981, Volume: 28, Issue:6 Topics: Alfaxalone Alfadolone Mixture; Humans; Pregnanes; Pregnanolone	1981
An early clinical assessment of the steroid anaesthetic Minaxolone. Canadian Anaesthetists' Society journal, 1980, Volume: 27, Issue:2 Topics: Adult; Anesthesia, Intravenous; Anesthetics; Blood Chemical Analysis; Blood Pressure; Drug Evaluation; Female; Humans; Postoperative Period; Pregnanes; Pregnanolone	1980
Pharmacokinetics of minaxolone. British journal of anaesthesia, 1980, Volume: 52, Issue:2 Topics: Anesthesia, Intravenous; Anesthetics; Animals; Half-Life; Humans; Kinetics; Pregnanes; Pregnanolone	1980
Minaxolone or Althesin supplemented by nitrous oxide. A study in anaesthesia for short operative procedures. Anaesthesia, 1980, Volume: 35, Issue:2 Topics: Adult; Alfaxalone Alfadolone Mixture; Anesthesia, Inhalation; Anesthesia, Intravenous; Female; Humans; Intraoperative Period; Male; Nitrous Oxide; Pregnanes; Pregnanolone; Time Factors	1980
Minaxolone and malignant hyperthermia. British journal of anaesthesia, 1980, Volume: 52, Issue:7 Topics: Animals; Malignant Hyperthermia; Pregnanes; Pregnanolone; Swine	1980
Respiratory effects of Minaxolone. Anaesthesia, 1980, Volume: 35, Issue:6 Topics: Anesthesia, Intravenous; Anesthetics; Apnea; Atropine; Female; Humans; Lorazepam; Lung Volume Measurements; Papaverine; Preanesthetic Medication; Pregnanes; Pregnanolone; Respiration; Scopolamine	1980
Effect of some i.v. anaesthetic agents on canine gastrointestinal motility. British journal of anaesthesia, 1981, Volume: 53, Issue:3 Topics: Action Potentials; Anesthesia, Intravenous; Anesthetics; Animals; Atropine; Dogs; Gastrointestinal Motility; Intestine, Small; Ketamine; Pentolinium Tartrate; Pregnanes; Pregnanolone; Thiopental	1981
Development of tolerance in mice to the sedative effects of the neuroactive steroid minaxolone following chronic exposure. Pharmacology, biochemistry, and behavior, 1997, Volume: 58, Issue:1 Topics: Anesthetics; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Flunitrazepam; GABA Agonists; GABA Modulators; GABA-A Receptor Antagonists; Hypnotics and Sedatives; In Vitro Techniques; Male; Membranes; Mice; Mice, Inbred Strains; Motor Activity; Muscimol; Pregnanolone; Radioligand Assay; Rats; Temazepam	1997
ORG 21465, a new water-soluble steroid hypnotic: more of the same or something different? British journal of anaesthesia, 1997, Volume: 79, Issue:4 Topics: Anesthetics; Anesthetics, Intravenous; Humans; Pregnanediones; Pregnanolone; Solubility	1997
The interaction of anaesthetic steroids with recombinant glycine and GABAA receptors. British journal of anaesthesia, 2004, Volume: 92, Issue:5 Topics: Anesthetics; Animals; Dose-Response Relationship, Drug; Evoked Potentials; Glycine; Oocytes; Patch-Clamp Techniques; Pregnanediones; Pregnanolone; Receptors, GABA-A; Recombinant Proteins; Structure-Activity Relationship; Xenopus laevis	2004
GABAA and glycine receptor-mediated transmission in rat lamina II neurones: relevance to the analgesic actions of neuroactive steroids. The Journal of physiology, 2007, Sep-15, Volume: 583, Issue:Pt 3 Topics: Anesthetics; Animals; Bicuculline; Desoxycorticosterone; Female; GABA Antagonists; GABA Modulators; Glycine Agents; Inhibitory Postsynaptic Potentials; Male; Membrane Potentials; Neural Inhibition; Posterior Horn Cells; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glycine; Strychnine; Synaptic Transmission	2007