minalrestat has been researched along with zopolrestat in 2 studies
| Studies (minalrestat) | Trials (minalrestat) | Recent Studies (post-2010) (minalrestat) | Studies (zopolrestat) | Trials (zopolrestat) | Recent Studies (post-2010) (zopolrestat) |
|---|---|---|---|---|---|
| 9 | 0 | 1 | 86 | 2 | 24 |
| Protein | Taxonomy | minalrestat (IC50) | zopolrestat (IC50) |
|---|---|---|---|
| Aldo-keto reductase family 1 member B10 | Homo sapiens (human) | 0.915 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 0.0153 | |
| Aldo-keto reductase family 1 member A1 | Homo sapiens (human) | 1.3545 | |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | 0.0229 | |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | 0.005 | |
| Aldo-keto reductase family 1 member B7 | Rattus norvegicus (Norway rat) | 0.049 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dhagat, U; El-Kabbani, O; Endo, S; Hara, A | 1 |
| El-Kabbani, O; Endo, S; Hara, A; Kitade, Y; Kuwata, K; Matsunaga, T; Zhao, HT | 1 |
2 other study(ies) available for minalrestat and zopolrestat
| Article | Year |
|---|---|
Inhibition of 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) by aldose reductase inhibitors.
Topics: 3-Hydroxysteroid Dehydrogenases; Aldehyde Reductase; Animals; Binding Sites; Enzyme Inhibitors; Mice; Models, Molecular; Protein Binding; Substrate Specificity | 2008 |
Chromene-3-carboxamide derivatives discovered from virtual screening as potent inhibitors of the tumour maker, AKR1B10.
Topics: Aldehyde Reductase; Aldehydes; Aldo-Keto Reductases; Antineoplastic Agents; Benzopyrans; Biomarkers, Tumor; Catalytic Domain; Computer Simulation; Databases, Factual; Drug Discovery; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Farnesol; HeLa Cells; Humans; Kinetics; Models, Molecular; Protein Binding; Recombinant Proteins; Substrate Specificity | 2010 |