minalrestat has been researched along with glyceraldehyde in 1 studies
*Glyceraldehyde: An aldotriose containing the propionaldehyde structure with hydroxy groups at the 2- and 3-positions. It is involved in the formation of ADVANCED GLYCOSYLATION END PRODUCTS. [MeSH]
*Glyceraldehyde: An aldotriose containing the propionaldehyde structure with hydroxy groups at the 2- and 3-positions. It is involved in the formation of ADVANCED GLYCOSYLATION END PRODUCTS. [MeSH]
Studies (minalrestat) | Trials (minalrestat) | Recent Studies (post-2010) (minalrestat) | Studies (glyceraldehyde) | Trials (glyceraldehyde) | Recent Studies (post-2010) (glyceraldehyde) |
---|---|---|---|---|---|
9 | 0 | 1 | 1,161 | 1 | 167 |
Protein | Taxonomy | minalrestat (IC50) | glyceraldehyde (IC50) |
---|---|---|---|
Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | 0.01 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (100.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Hohman, TC; Malamas, MS; Millen, J | 1 |
1 other study(ies) available for minalrestat and glyceraldehyde
Article | Year |
---|---|
Novel spirosuccinimide aldose reductase inhibitors derived from isoquinoline-1,3-diones: 2-[(4-bromo-2-fluorophenyl)methyl]-6- fluorospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrone and congeners. 1.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Cattle; Diabetes Mellitus, Experimental; Dogs; Drug Evaluation, Preclinical; Erythrocytes; Galactitol; Galactosemias; Glyceraldehyde; In Vitro Techniques; Isoquinolines; Lens, Crystalline; Male; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spiro Compounds; Stereoisomerism | 1994 |