miltefosine and antimony

miltefosine has been researched along with antimony in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (30.30)29.6817
2010's16 (48.48)24.3611
2020's7 (21.21)2.80

Authors

AuthorsStudies
Murray , HW1
Sundar, S1
Arana, B; Diaz, A; Rizzo, N1
Murray, HW1
Marty, P; Rosenthal, E1
Boelaert, M; Diap, G; Gerstl, S; Guerin, PJ; Meheus, F; Van der Stuyft, P; Vanlerberghe, V1
Mumtaz, N; Rahman, SB; ul Bari, A1
Minodier, P; Parola, P1
Blanc, P; Garnier, JM; Minodier, P; Noël, G; Retornaz, K; Uters, M1
Beck, JC; Berman, J; Davidson, C; Mings, S; Ondo, AL; Shanler, SD1
Duncan, RC; Kumar, D; Nakhasi, HL; Salotra, P; Singh, R1
Ampuero, J; Carvalho, EM; Guimarães, LH; Machado, PR; Penna, G; Rocha, AT; Schriefer, A; Sousa, RS; Talhari, A; Villasboas, L1
Bavchvarov, BI; Campillo, M; Castanys, S; Gamarro, F; López-Martín, C; Martínez-García, M; Pérez-Victoria, JM; Torrecillas, IR1
De Doncker, S; Decuypere, S; Dujardin, JC; Maes, L; Rijal, S; Vanaerschot, M1
Leprohon, P; Moreira, W; Ouellette, M1
Chatterjee, M; Ghosh, S; Pakrashi, S; Roy, D; Sarkar, A; Sen, S1
Boulet, G; Cos, P; Delputte, P; Dujardin, JC; Hendrickx, S; Lachaud, L; Maes, L; Mondelaers, A; Rijal, S1
Diaz-Toro, Y; Fernández, OL; Gomez, MA; Muvdi, S; Ovalle, C; Rodríguez, I; Saravia, NG; Valderrama, L1
Chatterjee, M; Singh, N; Sundar, S1
Coelho, AC; Cotrim, PC; Oliveira, JC; Reimão, JQ; Trinconi, CT; Uliana, SR1
Blackburn, G; Carter, KC; Coombs, GH; Cotton, JA; Downing, T; Dujardin, JC; Freeman, TM; Illingworth, CJ; Imamura, H; Khanal, B; Lonchamp, J; Rijal, S; Sanders, M; Shaw, CD1
Bifeld, E; Clos, J; Höhn, K; Tejera Nevado, P1
Bresson, E; Fernandez-Prada, C; Leprohon, P; Ouellette, M; Plourde, M; Roy, G; Sharma, M1
Aguado, B; Camacho, E; Castanys, S; Corvo, L; Dujardin, JC; Gamarro, F; García-Hernández, R; Imamura, H; Rastrojo, A; Requena, JM; Vargas, P1
Caljon, G; Cos, P; Delputte, P; Gielis, JF; Hendrickx, S; Maes, L; Van Bockstal, L; Van den Kerkhof, M1
Carregal, VM; Demicheli, C; Frézard, F; Fujiwara, RT; Islam, A; Lanza, JS; Rivas, L; Souza, DM1
Barral, A; Barral-Netto, M; Boaventura, V; Carvalho, EM; Corte, TWF; Guimarães, LH; Lago, T; Machado, PRL; Penna, G; Prates, FVO; Schriefer, A1
Bhattacharyya, M; Bodhale, NP; Pai, K; Saha, B; Sundar, S1
Ali, N; Ashraf, S; den Boer, M; Fernhout, J; Grobusch, MP; Kämink, S; Khan, SJ; Masih, B; Pylypenko, T; Ritmeijer, K; Ullah, A1
Alves, F; Brack, M; Dahal, P; Guerin, PJ; Halleux, CM; Hawryszkiewycz, A; Maguire, BJ; Ngu, R; Olliaro, PL; Rashan, S; Singh-Phulgenda, S; Stepniewska, K1
Murta, SMF; Santi, AMM; Santos, IFM; Silva, PA1
Alves, LL; Carvalho, JP; Cota, G; Freire, ML; Silva, SN; Souza, CSA1
de Groote, R; de Muylder, G; Domagalska, MA; Dujardin, JC; Maes, I; Monsieurs, P; Negreira, GH; Van den Broeck, F; Van Giel, D1

Reviews

8 review(s) available for miltefosine and antimony

ArticleYear
Treatment of visceral leishmaniasis (kala-azar): a decade of progress and future approaches.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2000, Volume: 4, Issue:3

    Topics: Adult; Amphotericin B; Animals; Antimony; Antiprotozoal Agents; Child; Humans; Leishmania donovani; Leishmaniasis, Visceral; Mice; Paromomycin; Phosphorylcholine; Treatment Outcome

2000
Chemotherapy of cutaneous leishmaniasis: a review.
    Medical microbiology and immunology, 2001, Volume: 190, Issue:1-2

    Topics: Antifungal Agents; Antimony; Leishmaniasis, Cutaneous; Meglumine; Meglumine Antimoniate; Ointments; Organometallic Compounds; Phosphorylcholine

2001
Progress in the treatment of a neglected infectious disease: visceral leishmaniasis.
    Expert review of anti-infective therapy, 2004, Volume: 2, Issue:2

    Topics: Amphotericin B; Antimony; Antiprotozoal Agents; Clinical Trials as Topic; Deoxycholic Acid; Drug Combinations; Drug Costs; Humans; Leishmaniasis, Visceral; Paromomycin; Phosphatidylcholines; Phosphatidylglycerols; Phosphorylcholine; Practice Guidelines as Topic

2004
[Visceral leishmaniases].
    La Revue du praticien, 2004, Dec-31, Volume: 54, Issue:20

    Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Animals; Antimony; Antiprotozoal Agents; Brazil; Child, Preschool; Dogs; Ethiopia; Europe; Humans; Incidence; India; Infant; Infant, Newborn; Leishmaniasis, Visceral; Phosphorylcholine; Prevalence; Time Factors; Zoonoses

2004
Cutaneous leishmaniasis treatment.
    Travel medicine and infectious disease, 2007, Volume: 5, Issue:3

    Topics: Administration, Cutaneous; Administration, Oral; Aminoquinolines; Amphotericin B; Animals; Antimony; Antiprotozoal Agents; Humans; Imiquimod; Injections, Intralesional; Injections, Intramuscular; Leishmaniasis, Cutaneous; Paromomycin; Pentamidine; Phosphorylcholine

2007
[Treatment of visceral leishmaniasis in children].
    Medecine tropicale : revue du Corps de sante colonial, 2007, Volume: 67, Issue:1

    Topics: Amphotericin B; Antimony; Antimony Sodium Gluconate; Antiprotozoal Agents; Child; Humans; Leishmaniasis, Visceral; Meglumine; Meglumine Antimoniate; Organometallic Compounds; Phosphorylcholine

2007
Serious adverse events following treatment of visceral leishmaniasis: A systematic review and meta-analysis.
    PLoS neglected tropical diseases, 2021, Volume: 15, Issue:3

    Topics: Amphotericin B; Antimony; Antiprotozoal Agents; Deoxycholic Acid; Drug Combinations; Humans; Leishmaniasis, Visceral; Phosphorylcholine

2021
The cure rate after different treatments for mucosal leishmaniasis in the Americas: A systematic review.
    PLoS neglected tropical diseases, 2022, Volume: 16, Issue:11

    Topics: Antimony; Humans; Leishmaniasis, Mucocutaneous; Pentoxifylline

2022

Trials

3 trial(s) available for miltefosine and antimony

ArticleYear
Miltefosine in cutaneous leishmaniasis.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2007, Volume: 17, Issue:3

    Topics: Adult; Antimony; Antiprotozoal Agents; Female; Humans; Leishmaniasis, Cutaneous; Male; Meglumine; Meglumine Antimoniate; Organometallic Compounds; Phosphorylcholine

2007
Miltefosine in the treatment of cutaneous leishmaniasis caused by Leishmania braziliensis in Brazil: a randomized and controlled trial.
    PLoS neglected tropical diseases, 2010, Dec-21, Volume: 4, Issue:12

    Topics: Abdominal Pain; Administration, Oral; Adolescent; Adult; Aged; Antimony; Antiprotozoal Agents; Brazil; Child; Child, Preschool; Female; Humans; Leishmania braziliensis; Leishmaniasis, Cutaneous; Male; Middle Aged; Nausea; Phosphorylcholine; Prevalence; Treatment Outcome; Vomiting; Young Adult

2010
A Double-blind, Randomized Trial to Evaluate Miltefosine and Topical Granulocyte Macrophage Colony-stimulating Factor in the Treatment of Cutaneous Leishmaniasis Caused by Leishmania braziliensis in Brazil.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021, 10-05, Volume: 73, Issue:7

    Topics: Antimony; Antiprotozoal Agents; Brazil; Granulocyte-Macrophage Colony-Stimulating Factor; Granulocytes; Humans; Leishmania braziliensis; Leishmaniasis, Cutaneous; Macrophage Colony-Stimulating Factor; Phosphorylcholine; Treatment Outcome

2021

Other Studies

22 other study(ies) available for miltefosine and antimony

ArticleYear
Drug resistance in Indian visceral leishmaniasis.
    Tropical medicine & international health : TM & IH, 2001, Volume: 6, Issue:11

    Topics: Aminoquinolines; Amphotericin B; Antimony; Antiprotozoal Agents; Dose-Response Relationship, Drug; Drug Resistance; Geography; History, 20th Century; History, 21st Century; Humans; India; Leishmaniasis, Visceral; Paromomycin; Pentamidine; Phosphorylcholine; Treatment Outcome

2001
Drug policy for visceral leishmaniasis: a cost-effectiveness analysis.
    Tropical medicine & international health : TM & IH, 2007, Volume: 12, Issue:2

    Topics: Amphotericin B; Antimony; Antiprotozoal Agents; Cost-Benefit Analysis; Decision Trees; Deoxycholic Acid; Drug Combinations; Endemic Diseases; Health Care Costs; Humans; Leishmaniasis, Visceral; Phosphorylcholine; Treatment Outcome

2007
Cutaneous leishmaniasis with boggy induration and simultaneous mucosal disease.
    The American journal of tropical medicine and hygiene, 2009, Volume: 80, Issue:1

    Topics: Amphotericin B; Antimony; Antiprotozoal Agents; Biopsy; Bolivia; Drug Therapy, Combination; Female; Humans; Leishmaniasis, Cutaneous; Middle Aged; Phosphorylcholine; Travel; Treatment Outcome

2009
Overexpression of histone H2A modulates drug susceptibility in Leishmania parasites.
    International journal of antimicrobial agents, 2010, Volume: 36, Issue:1

    Topics: Amphotericin B; Antimony; Antiprotozoal Agents; Drug Resistance; Histones; Humans; India; Leishmania donovani; Mitogen-Activated Protein Kinase 1; Oligonucleotide Array Sequence Analysis; Phosphorylcholine; Protozoan Proteins

2010
Sitamaquine overcomes ABC-mediated resistance to miltefosine and antimony in Leishmania.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:8

    Topics: Aminoquinolines; Antimony; Antiprotozoal Agents; ATP-Binding Cassette Transporters; Drug Resistance, Bacterial; Ketoconazole; Leishmania tropica; Leishmaniasis; Phosphorylcholine; Protein Binding

2011
Antimonial resistance in Leishmania donovani is associated with increased in vivo parasite burden.
    PloS one, 2011, Volume: 6, Issue:8

    Topics: Animals; Antimony; Antiprotozoal Agents; Drug Resistance; India; Leishmania donovani; Liver; Mice; Mice, Inbred BALB C; Phosphorylcholine; Spleen

2011
Tolerance to drug-induced cell death favours the acquisition of multidrug resistance in Leishmania.
    Cell death & disease, 2011, Sep-01, Volume: 2

    Topics: Amphotericin B; Antimony; Antiprotozoal Agents; Apoptosis; Cell Death; Drug Resistance, Multiple; Drug Tolerance; Leishmania infantum; Methotrexate; Paromomycin; Phosphorylcholine; Reactive Oxygen Species

2011
Leishmania strains causing self-healing cutaneous leishmaniasis have greater susceptibility towards oxidative stress.
    Free radical research, 2012, Volume: 46, Issue:5

    Topics: Antimony; Free Radicals; Humans; Leishmania major; Leishmaniasis, Cutaneous; Leishmaniasis, Visceral; Macrophages; Nitric Oxide; Oxidative Stress; Phosphorylcholine; Superoxide Dismutase

2012
Experimental selection of paromomycin and miltefosine resistance in intracellular amastigotes of Leishmania donovani and L. infantum.
    Parasitology research, 2014, Volume: 113, Issue:5

    Topics: Animals; Antimony; Antiprotozoal Agents; Drug Resistance; Female; Humans; Leishmania donovani; Macrophages; Mice; Parasitic Sensitivity Tests; Paromomycin; Phosphorylcholine

2014
Miltefosine and antimonial drug susceptibility of Leishmania Viannia species and populations in regions of high transmission in Colombia.
    PLoS neglected tropical diseases, 2014, Volume: 8, Issue:5

    Topics: Adolescent; Adult; Aged; Antimony; Child; Child, Preschool; Cohort Studies; Colombia; Drug Resistance; Humans; Infant; Leishmania; Leishmaniasis; Meglumine; Meglumine Antimoniate; Middle Aged; Organometallic Compounds; Phosphorylcholine; Randomized Controlled Trials as Topic; Young Adult

2014
The overexpression of genes of thiol metabolism contribute to drug resistance in clinical isolates of visceral leishmaniasis (kala azar) in India.
    Parasites & vectors, 2014, Dec-17, Volume: 7

    Topics: Amphotericin B; Animals; Antimony; Antiprotozoal Agents; Drug Resistance; Glutamate-Cysteine Ligase; Humans; India; Leishmania donovani; Leishmaniasis, Visceral; Membrane Transport Proteins; Mutation; Phosphorylcholine; Protozoan Proteins; Sulfhydryl Compounds

2014
Generation of luciferase-expressing Leishmania infantum chagasi and assessment of miltefosine efficacy in infected hamsters through bioimaging.
    PLoS neglected tropical diseases, 2015, Volume: 9, Issue:2

    Topics: Animals; Antimony; Antiprotozoal Agents; Cricetinae; Humans; India; Leishmania infantum; Leishmaniasis, Visceral; Luciferases; Parasite Load; Phosphorylcholine; Recombinant Proteins

2015
In vitro selection of miltefosine resistance in promastigotes of Leishmania donovani from Nepal: genomic and metabolomic characterization.
    Molecular microbiology, 2016, Volume: 99, Issue:6

    Topics: Animals; Antimony; Antiprotozoal Agents; Drug Resistance; Female; Leishmania donovani; Leishmaniasis, Visceral; Lipid Metabolism; Membrane Transport Proteins; Mice; Mice, Inbred BALB C; Mutation; Nepal; Parasitic Sensitivity Tests; Phosphorylcholine

2016
A Telomeric Cluster of Antimony Resistance Genes on Chromosome 34 of Leishmania infantum.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:9

    Topics: Antimony; Antimony Sodium Gluconate; Antiprotozoal Agents; Cadmium; Cloning, Molecular; Copper; Drosophila Proteins; Drug Resistance; Exosomes; Gene Expression; Heat-Shock Proteins; High-Throughput Nucleotide Sequencing; Leishmania infantum; Life Cycle Stages; Multigene Family; Phosphorylcholine; Protozoan Proteins; Telomere

2016
High-throughput Cos-Seq screen with intracellular Leishmania infantum for the discovery of novel drug-resistance mechanisms.
    International journal for parasitology. Drugs and drug resistance, 2018, Volume: 8, Issue:2

    Topics: Amphotericin B; Animals; Antimony; Antiprotozoal Agents; Cosmids; CRISPR-Cas Systems; Drug Resistance; Gene Library; High-Throughput Nucleotide Sequencing; Leishmania infantum; Leishmaniasis; Life Cycle Stages; Macrophages; Phosphorylcholine

2018
Genomic and transcriptomic alterations in Leishmania donovani lines experimentally resistant to antileishmanial drugs.
    International journal for parasitology. Drugs and drug resistance, 2018, Volume: 8, Issue:2

    Topics: Antimony; Antiprotozoal Agents; Drug Resistance, Multiple; Genomics; Leishmania donovani; Leishmania infantum; Leishmania major; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Paromomycin; Phenotype; Phosphorylcholine; Transcriptome

2018
Impact of primary mouse macrophage cell types on Leishmania infection and in vitro drug susceptibility.
    Parasitology research, 2018, Volume: 117, Issue:11

    Topics: Amphotericin B; Animals; Antimony; Antiprotozoal Agents; Cells, Cultured; Drug Resistance; Female; Interleukin-6; Leishmania infantum; Leishmaniasis; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nitric Oxide; Parasitic Sensitivity Tests; Paromomycin; Phosphorylcholine; Reactive Oxygen Species; Tumor Necrosis Factor-alpha

2018
Combination oral therapy against Leishmania amazonensis infection in BALB/c mice using nanoassemblies made from amphiphilic antimony(V) complex incorporating miltefosine.
    Parasitology research, 2019, Volume: 118, Issue:10

    Topics: Administration, Oral; Animals; Antimony; Antiprotozoal Agents; Disease Models, Animal; Female; Leishmania mexicana; Leishmaniasis, Cutaneous; Mice, Inbred BALB C; Nanoparticles; Phosphorylcholine

2019
The drug resistance mechanisms in Leishmania donovani are independent of immunosuppression.
    Cytokine, 2021, Volume: 145

    Topics: Amphotericin B; Animals; Antimony; Cytokines; Drug Resistance; Immunosuppression Therapy; Leishmania donovani; Leishmaniasis, Visceral; Macrophages; Mice; Mice, Inbred BALB C; Phosphorylcholine; Protozoan Proteins

2021
Effectiveness of miltefosine in cutaneous leishmaniasis caused by Leishmania tropica in Pakistan after antimonial treatment failure or contraindications to first line therapy-A retrospective analysis.
    PLoS neglected tropical diseases, 2021, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Aged; Antimony; Antiprotozoal Agents; Child; Female; Humans; Leishmania tropica; Leishmaniasis, Cutaneous; Male; Middle Aged; Patient Outcome Assessment; Phosphorylcholine; Retrospective Studies; Treatment Failure; Young Adult

2021
Downregulation of FeSOD-A expression in Leishmania infantum alters trivalent antimony and miltefosine susceptibility.
    Parasites & vectors, 2021, Jul-15, Volume: 14, Issue:1

    Topics: Antimony; Antiprotozoal Agents; Down-Regulation; Leishmania infantum; Mutation; Oxidative Stress; Phosphorylcholine; Superoxide Dismutase

2021
The adaptive roles of aneuploidy and polyclonality in Leishmania in response to environmental stress.
    EMBO reports, 2023, 09-06, Volume: 24, Issue:9

    Topics: Aneuploidy; Antimony; Chromosomes; Humans; Leishmania

2023