milrinone has been researched along with theophylline in 37 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (29.73) | 18.7374 |
| 1990's | 12 (32.43) | 18.2507 |
| 2000's | 11 (29.73) | 29.6817 |
| 2010's | 3 (8.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Cortijo, J; Morcillo, EJ; Ortiz, JL; Vallés, JM | 1 |
| Bethke, T; Mehl, H; Meyer, W; Schmitz, W; Scholz, H; Thomas, K; Wenzlaff, H | 1 |
| Porsius, AJ; Post, MJ; te Biesebeek, JD; van Rooij, HH; Wemer, J | 4 |
| Belluco, P; Borea, PA; Dorigo, P; Gaion, RM; Maragno, I; Mosti, L | 1 |
| Meyer, W; Scholz, H | 1 |
| Brown, L; Erdmann, E; Lorenz, B | 1 |
| Gillespie, E | 1 |
| Coker, SJ; Holbrook, M | 1 |
| Cottney, J; Marsden, G; Nicholson, CD; Shahid, M | 1 |
| Decker, N; Grima, M; Schwartz, J | 1 |
| Le Jemtel, TH; Maskin, CS; Sonnenblick, EH | 1 |
| Farah, A; Kabela, E; Mendez, R; Pastelin, G | 1 |
| Drescher, P; Eckert, RE; Madsen, PO | 1 |
| Pfaffendorf, M; van Wezel, HB; van Zwieten, PA; Vroom, MB | 1 |
| Dahl, SG; Lagente, V; Payne, AN; Planquois, JM; Ruffin-Morin, Y | 2 |
| Anfossi, G; Cavalot, F; Massucco, P; Mattiello, L; Mularoni, E; Piretto, V; Trovati, M | 1 |
| Agneter, E; Brunner, M; Burgdorff, T; Dorner, G; Eichler, HG; Jansen, B; Müller, M; Singer, EA | 1 |
| Inagaki, N; Kobayashi, J; Nagai, H; Nagao, T; Nakao, T; Tanaka, H; Usami, E; Watanabe, S; Yamazaki, F; Yoshimura, T | 1 |
| Heintz, B; Kirsten, D; Kirsten, R; Nelson, K | 1 |
| Chambers, DJ; Featherstone, RL; Kelly, FJ | 1 |
| Ozdem, SS; Sadan, G; Tasatargil, A | 1 |
| Abdollahi, M; Khorasani, R; Milani, E; Nikfar, S; Zamani, MJ | 1 |
| Onur, R; Yenisehirli, A | 1 |
| Batzias, GC; Koutsoviti-Papadopoulou, M; Psarra, TA | 1 |
| Chao, PC; Hamilton, KL | 1 |
| Iwasaki, S; Watanabe, A; Yamakage, M; Zhou, J | 1 |
2 review(s) available for milrinone and theophylline
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Clinical pharmacokinetics of vasodilators. Part II.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Alprostadil; Amrinone; Carbazoles; Carvedilol; Enoximone; Female; Humans; Iloprost; Imidazoles; Indoramin; Isosorbide Dinitrate; Labetalol; Milrinone; Molsidomine; Nitroglycerin; Nitroprusside; Oxyfedrine; Pentaerythritol Tetranitrate; Phosphodiesterase Inhibitors; Piperazines; Prazosin; Pregnancy; Propanolamines; Pyridones; Theophylline; Trapidil; Vasodilator Agents | 1998 |
1 trial(s) available for milrinone and theophylline
| Article | Year |
|---|---|
In vivo drug-response measurements in target tissues by microdialysis.
Topics: Adult; Cyclic AMP; Dose-Response Relationship, Drug; Histamine; Humans; Male; Microdialysis; Milrinone; Muscle, Skeletal; p-Methoxy-N-methylphenethylamine; Phosphodiesterase Inhibitors; Pyridones; Skin; Theophylline | 1997 |
34 other study(ies) available for milrinone and theophylline
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Rolipram inhibits PAF-induced airway microvascular leakage in guinea-pig: a comparison with milrinone and theophylline.
Topics: Animals; Capillary Permeability; Evans Blue; Guinea Pigs; Milrinone; Phosphodiesterase Inhibitors; Platelet Activating Factor; Pyridones; Pyrrolidinones; Respiratory System; Rolipram; Theophylline | 1992 |
Effects of the triazolopyrimidine trapidil on force of contraction, beating frequency and phosphodiesterase I--IV activity in guinea-pig hearts.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Chromatography, DEAE-Cellulose; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Isoenzymes; Male; Milrinone; Myocardial Contraction; Myocardium; Phosphodiesterase Inhibitors; Pyridones; Theophylline; Trapidil | 1991 |
Effects of milrinone, sulmazole and theophylline on adenosine enhancement of antigen-induced bronchoconstriction and mediator release in rat isolated lungs.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Adenosine; Animals; Antigens; Bronchoconstriction; Chromatography, High Pressure Liquid; Histamine Release; Imidazoles; In Vitro Techniques; Lung; Male; Milrinone; Perfusion; Pyridones; Rats; Rats, Inbred Strains; Serotonin; Theophylline | 1991 |
An analysis of the mechanism of the inotropic action of some milrinone analogues in guinea-pig isolated atria.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Carbachol; Cardiotonic Agents; Electric Stimulation; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Milrinone; Myocardial Contraction; Phenylisopropyladenosine; Propranolol; Pyridones; Reserpine; Theophylline | 1991 |
Phosphodiesterase-inhibiting properties of newer inotropic agents.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyridines; Amrinone; Animals; Calcium; Cardiotonic Agents; Cyclic AMP; Dose-Response Relationship, Drug; Guinea Pigs; Imidazoles; Milrinone; Myocardial Contraction; Phosphodiesterase Inhibitors; Pyridazines; Pyridones; Theophylline | 1986 |
Reduced positive inotropic effects in diseased human ventricular myocardium.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Aged; Calcium; Dobutamine; Dopamine; Dose-Response Relationship, Drug; Female; Heart Diseases; Histamine; Humans; Isoproterenol; Male; Middle Aged; Milrinone; Myocardial Contraction; Myocardium; Pyridones; Stimulation, Chemical; Theophylline | 1986 |
Anagrelide: a potent and selective inhibitor of platelet cyclic AMP phosphodiesterase enzyme activity.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Blood Platelets; Dose-Response Relationship, Drug; Humans; Milrinone; Platelet Aggregation Inhibitors; Pyridones; Quinazolines; Theophylline | 1988 |
Anti-allergic effects of milrinone and sulmazole in isolated rat lungs in comparison with theophylline.
Topics: Airway Resistance; Animals; Histamine Release; Imidazoles; In Vitro Techniques; Leukotrienes; Lung; Male; Milrinone; Phosphodiesterase Inhibitors; Pulmonary Circulation; Pyridones; Rats; Rats, Inbred Strains; Serotonin; Theophylline; Vasoconstriction | 1989 |
Comparison of the effects of isobutylmethylxanthine and milrinone on ischaemia-induced arrhythmias and platelet aggregation in anaesthetized rabbits.
Topics: 1-Methyl-3-isobutylxanthine; Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Gas Analysis; Blood Pressure; Cardiotonic Agents; Coronary Disease; Electrocardiography; Heart Rate; Male; Milrinone; Phosphodiesterase Inhibitors; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridones; Rabbits; Theophylline | 1989 |
A comparison of the inotropic activity of Org 30029, IBMX, milrinone and rolipram in rat papillary muscles.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cardiotonic Agents; In Vitro Techniques; Milrinone; Myocardial Contraction; Organic Chemicals; Papillary Muscles; Pyridones; Pyrrolidinones; Rats; Rolipram; Theophylline | 1989 |
In vivo anaphylaxis in the rat: effects of phosphodiesterase inhibitors.
Topics: Anaphylaxis; Animals; Antigens; Cardiovascular System; Imidazoles; Lung; Male; Milrinone; Phosphodiesterase Inhibitors; Pyridones; Rats; Rats, Inbred Strains; Theophylline | 1989 |
Comparison of the anti-anaphylactic effects of milrinone, sulmazole and theophylline in the rat.
Topics: Acid-Base Equilibrium; Airway Resistance; Anaphylaxis; Animals; Imidazoles; Lung Compliance; Male; Milrinone; Phosphodiesterase Inhibitors; Pulmonary Circulation; Pyridones; Rats; Rats, Inbred Strains; Theophylline; Vasoconstriction | 1989 |
Effect of some new cardiotonic agents on synaptosomal sodium uptake.
Topics: Animals; Cardiotonic Agents; Guinea Pigs; Heart Atria; Imidazoles; Male; Milrinone; Protoveratrines; Pyridones; Quinazolines; Rats; Rats, Inbred Strains; Sodium; Synaptosomes; Tetrodotoxin; Theophylline; Time Factors | 1986 |
Inotropic drugs for treatment of the failing heart.
Topics: Aminophylline; Aminopyridines; Amrinone; Cardiotonic Agents; Catecholamines; Digitalis Glycosides; Glucagon; Heart Failure; Hemodynamics; Humans; Milrinone; Myocardial Contraction; Pyridones; Receptors, Adrenergic, beta; Theophylline | 1984 |
The search for a digitalis substitute II milrinone (Win 47203). Its action on the heart-lung preparation of the dog.
Topics: Animals; Cardiotonic Agents; Dinitrophenols; Dogs; Heart; Heart Failure; Milrinone; Nifedipine; Papaverine; Pentobarbital; Propranolol; Pyridones; Theophylline | 1983 |
Smooth muscle contractility in prostatic hyperplasia: role of cyclic adenosine monophosphate.
Topics: Bucladesine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Male; Milrinone; Muscle Contraction; Muscle, Smooth; Papaverine; Phenylephrine; Prostatic Hyperplasia; Pyridones; Theophylline | 1994 |
Effect of phosphodiesterase inhibitors on human arteries in vitro.
Topics: Adolescent; Adult; Amrinone; Analgesics; Anilides; Arginine; Arteries; Dipyridamole; Enoximone; Female; Glyburide; Humans; In Vitro Techniques; Middle Aged; Milrinone; Phosphodiesterase Inhibitors; Pyridones; Theophylline; Vasoconstriction; Vasodilation | 1996 |
Salbutamol potentiates the relaxant effects of selective phosphodiesterase inhibitors on guinea pig isolated trachea.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adrenergic beta-Agonists; Albuterol; Animals; Drug Synergism; Guanidines; Guinea Pigs; Histamine; In Vitro Techniques; Male; Milrinone; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Osmolar Concentration; Phosphodiesterase Inhibitors; Purinones; Pyridazines; Pyridones; Pyrrolidinones; Rolipram; Theophylline; Trachea | 1996 |
Interplay between milrinone and adenosine in the inhibition of human platelet response.
Topics: Adenosine; Adenosine Diphosphate; Adult; Blood Platelets; Collagen; Cyclic AMP; Dipyridamole; Epinephrine; Humans; In Vitro Techniques; Male; Milrinone; Phosphodiesterase Inhibitors; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridones; Theophylline | 1996 |
Differential inhibition by selective phosphodiesterase inhibitors of antigen, LTC4 and histamine-induced contraction of guinea-pig isolated trachea.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Bronchoconstrictor Agents; Bronchodilator Agents; Guanidines; Guinea Pigs; Histamine Antagonists; In Vitro Techniques; Leukotriene C4; Male; Milrinone; Muscle Tonus; Ovalbumin; Phosphodiesterase Inhibitors; Purinones; Pyridazines; Pyridones; Pyrrolidinones; Rolipram; Theophylline; Trachea | 1996 |
Modulation of Th1- and Th2-like cytokine production from mitogen-stimulated human peripheral blood mononuclear cells by phosphodiesterase inhibitors.
Topics: Adrenergic beta-Agonists; Bucladesine; Humans; In Vitro Techniques; Interferon-gamma; Interleukins; Leukocytes, Mononuclear; Milrinone; Mitogens; Phosphodiesterase Inhibitors; Pyridones; Pyrrolidinones; Rolipram; Th1 Cells; Th2 Cells; Theophylline | 1998 |
Comparison of phosphodiesterase inhibitors of differing isoenzyme selectivity added to St. Thomas' hospital cardioplegic solution used for hypothermic preservation of rat lungs.
Topics: Animals; Bicarbonates; Calcium Chloride; Hypothermia, Induced; Lung; Lung Transplantation; Magnesium; Milrinone; Oxygen; Phosphodiesterase Inhibitors; Potassium Chloride; Pulmonary Gas Exchange; Purinones; Rats; Rats, Wistar; Reperfusion Injury; Rolipram; Sodium Chloride; Theophylline; Vascular Resistance | 2000 |
The effects of selective phosphodiesterase III and V inhibitors on adrenergic and non-adrenergic, non-cholinergic relaxation responses of guinea-pig pulmonary arteries.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine; Animals; Arginine; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 5; Drug Synergism; Electric Stimulation; Guinea Pigs; Histamine; Isoproterenol; Male; Milrinone; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitroprusside; Oxadiazoles; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pulmonary Artery; Purinones; Quinoxalines; Receptors, Adrenergic; Receptors, Cholinergic; Signal Transduction; Tetrodotoxin; Theophylline | 2003 |
Reduction of diabetes-induced oxidative stress by phosphodiesterase inhibitors in rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Lipid Peroxidation; Male; Milrinone; Oxidative Stress; Phosphodiesterase Inhibitors; Piperazines; Purines; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones; Theophylline; Thiobarbituric Acid Reactive Substances | 2005 |
Positive inotropic and negative chronotropic effects of proton pump inhibitors in isolated rat atrium.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Heart Atria; Imidazoles; In Vitro Techniques; Lansoprazole; Male; Milrinone; Myocardial Contraction; Omeprazole; Ouabain; Phosphodiesterase Inhibitors; Proton Pump Inhibitors; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Theophylline; Verapamil | 2005 |
Milrinone and theophylline act as lower oesophageal sphincter relaxing agents: a comparative pharmacodynamic study in the rabbit.
Topics: Animals; Bronchodilator Agents; Esophageal Sphincter, Lower; Female; Male; Milrinone; Muscle Relaxation; Papaverine; Rabbits; Theophylline; Vasodilator Agents; Verapamil | 2009 |
Genistein stimulates electrogenic Cl- secretion via phosphodiesterase modulation in the mouse jejunum.
Topics: Animals; Bumetanide; Chloride-Bicarbonate Antiporters; Electrophysiology; Genistein; Jejunum; Male; Mice; Milrinone; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Sodium Potassium Chloride Symporter Inhibitors; Theophylline | 2009 |
Synergic bronchodilator effects of a phosphodiesterase 3 inhibitor olprinone with a volatile anaesthetic sevoflurane in ovalbumin-sensitised guinea pigs.
Topics: Acetylcholine; Airway Resistance; Anesthetics, Inhalation; Animals; Bronchial Hyperreactivity; Bronchoconstriction; Bronchodilator Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Imidazoles; Lung Compliance; Male; Methyl Ethers; Milrinone; Ovalbumin; Phosphodiesterase 3 Inhibitors; Pyridones; Sevoflurane; Theophylline; Time Factors | 2011 |