milrinone and imazodan

milrinone has been researched along with imazodan in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199010 (62.50)18.7374
1990's5 (31.25)18.2507
2000's1 (6.25)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bruno, JJ; Hirschfeld, DR; Maloney, PJ; Martinez, GR; Walker, KA; Yang, DS1
Bell, SC; Combs, DW; Falotico, R; Haertlein, B; Klaubert, DH; Lakas-Weiss, C; Moore, JB; Rampulla, MS; Tobia, AJ1
Bobowski, G; Bristol, JA; Burke, SE; Evans, DB; Newton, RS; Sircar, I; Steffen, RP; Weishaar, RE1
Bristol, JA; Kobylarz, D; Moos, WH; Sircar, I; Weishaar, RE1
Bristol, JA; Humblet, CC; McPhail, AT; Moos, WH; Rithner, C; Sircar, I; Weishaar, RE1
Bagli, J; Bogri, T; Lee, DK; McQuillan, J; Palameta, B; Peseckis, S; Rakhit, S1
Bobowski, G; Bristol, JA; Duell, BL; Evans, DB; Sircar, I1
Erhardt, PW1
Hayes, JS; Kauffman, RF; Krushinski, JH; Pollock, GD; Robertson, DW; Wilson, H1
Cantor, E; Chou, YL; Erhardt, PW; Hagedorn, AA; Ingebretsen, WR; Lampe, JW; Lumma, WC; Pang, D; Pease, CA; Wohl, RA1
Beedle, EE; Hayes, JS; Kauffman, RF; Krushinski, JH; Pollock, GD; Robertson, DW; Wilson, H; Wyss, V1
Bristol, JA; Evans, DB; Moos, WH; Sircar, I; Weishaar, RE1
Coates, WJ; Connolly, B; Dhanak, D; Flynn, ST; Worby, A1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Mensah, LM; Murray, KJ; Worby, A1
Heaslip, R; Nielson, CP; Sturm, RJ; Vestal, RE1

Reviews

1 review(s) available for milrinone and imazodan

ArticleYear
In search of the digitalis replacement.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Cardiotonic Agents; Cyclic AMP; Digitalis Glycosides; Heart Failure; Humans; Myocardial Contraction; Receptors, Adrenergic, beta; Structure-Activity Relationship

1987

Other Studies

15 other study(ies) available for milrinone and imazodan

ArticleYear
3,4-Dihydroquinolin-2(1H)-ones as combined inhibitors of thromboxane A2 synthase and cAMP phosphodiesterase.
    Journal of medicinal chemistry, 1992, Feb-21, Volume: 35, Issue:4

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Animals; Aorta; Blood Platelets; Fibrinolytic Agents; Humans; Hypertension; Male; Microsomes; Platelet Aggregation; Platelet Aggregation Inhibitors; Quinolones; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Swine; Thromboembolism; Thromboxane B2; Thromboxane-A Synthase

1992
6-Benzoxazinylpyridazin-3-ones: potent, long-acting positive inotrope and peripheral vasodilator agents.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:1

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Benzoxazines; Cardiotonic Agents; Chemical Phenomena; Chemistry; Dogs; Molecular Structure; Myocardial Contraction; Myocardium; Oxazines; Pyridazines; Stimulation, Chemical; Structure-Activity Relationship; Vasodilation

1990
Cardiotonic agents. 9. Synthesis and biological evaluation of a series of (E)-4,5-dihydro-6-[2-[4-(1H-imidazol-1-yl)phenyl]ethenyl]-3 (2H)-pyridazinones: a novel class of compounds with positive inotropic, antithrombotic, and vasodilatory activities for t
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cardiotonic Agents; Dogs; Female; Fibrinolytic Agents; Heart Failure; Humans; Imidazoles; Male; Myocardial Contraction; Platelet Aggregation; Pyridazines; Structure-Activity Relationship; Vasodilator Agents

1989
Cardiotonic agents. 7. Inhibition of separated forms of cyclic nucleotide phosphodiesterase from guinea pig cardiac muscle by 4,5-dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones and related compounds. Structure-activity relationships and correl
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:11

    Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Cardiotonic Agents; Dogs; Female; Guinea Pigs; Imidazoles; Male; Myocardial Contraction; Myocardium; Pyridazines; Structure-Activity Relationship

1987
Cardiotonic agents. 8. Selective inhibitors of adenosine 3',5'-cyclic phosphate phosphodiesterase III. Elaboration of a five-point model for positive inotropic activity.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:11

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Cardiotonic Agents; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Myocardial Contraction; Spectrophotometry, Infrared; X-Ray Diffraction

1987
Chemistry and positive inotropic effect of pelrinone and related derivatives. A novel class of 2-methylpyrimidones as inotropic agents.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:4

    Topics: Animals; Blood Pressure; Cats; Dogs; Heart Rate; Models, Molecular; Myocardial Contraction; Pyrimidines; Sodium-Potassium-Exchanging ATPase; Stimulation, Chemical; Structure-Activity Relationship

1988
Cardiotonic agents. 2. Synthesis and structure-activity relationships of 4,5-dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones: a new class of positive inotropic agents.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:10

    Topics: Adrenergic beta-Antagonists; Animals; Cardiotonic Agents; Chemical Phenomena; Chemistry, Physical; Dogs; Heart Failure; Imidazoles; Myocardial Contraction; Pyridazines; Structure-Activity Relationship

1985
Dihydropyridazinone cardiotonics: synthesis and inotropic activity of 5'-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)spiro[cycloalkane- 1,3'-[3H]indol]-2'(1'H)-ones.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:5

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Chemical Phenomena; Chemistry; Dogs; Female; Indoles; Isoenzymes; Male; Myocardial Contraction; Myocardium; Pyridazines; Sarcoplasmic Reticulum; Spiro Compounds; Stimulation, Chemical; Structure-Activity Relationship

1987
Cardiotonic agents. 2. (Imidazolyl)aroylimidazolones, highly potent and selective positive inotropic agents.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:8

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Blood Pressure; Chemical Phenomena; Chemistry; Ferrets; Heart Rate; Imidazoles; Myocardial Contraction; Papillary Muscles; Stimulation, Chemical; Structure-Activity Relationship

1987
Dihydropyridazinone cardiotonics: the discovery and inotropic activity of 1,3-dihydro-3,3-dimethyl-5-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)-2H -indol-2- one.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:10

    Topics: Administration, Oral; Animals; Cardiotonic Agents; Cats; Dogs; Female; In Vitro Techniques; Indoles; Male; Myocardial Contraction; Oxindoles; Platelet Aggregation; Pyridazines; Structure-Activity Relationship

1986
Cardiotonic agents. 1. 4,5-Dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3 (2H)-pyridazinones: novel positive inotropic agents for the treatment of congestive heart failure.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:9

    Topics: Animals; Cardiotonic Agents; Dogs; Guinea Pigs; Heart Failure; Myocardial Contraction; Phosphodiesterase Inhibitors; Pyridazines

1984
Cyclic nucleotide phosphodiesterase inhibition by imidazopyridines: analogues of sulmazole and isomazole as inhibitors of the cGMP specific phosphodiesterase.
    Journal of medicinal chemistry, 1993, May-14, Volume: 36, Issue:10

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Imidazoles; Isoenzymes; Phosphodiesterase Inhibitors; Pyridines; Structure-Activity Relationship

1993
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Myofibrillar bound cyclic nucleotide phosphodiesterase in heart and skeletal muscle.
    Biochemical Society transactions, 1992, Volume: 20, Issue:2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Cell Fractionation; Guinea Pigs; Kinetics; Milrinone; Muscles; Myocardium; Myofibrils; Pyridazines; Pyridones; Pyrrolidinones; Rats; Rolipram; Xanthines

1992
Effects of selective phosphodiesterase inhibitors on the polymorphonuclear leukocyte respiratory burst.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:5

    Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adrenergic beta-Agonists; Adult; Calcimycin; Chromatography, Ion Exchange; Humans; Isoenzymes; Isoproterenol; Middle Aged; Milrinone; Neutrophils; Oxygen Consumption; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Purinones; Pyridazines; Pyridones; Pyrrolidinones; Rolipram; Superoxides

1990