Page last updated: 2024-08-24

milnacipran and fluvoxamine

milnacipran has been researched along with fluvoxamine in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.78)18.2507
2000's23 (63.89)29.6817
2010's11 (30.56)24.3611
2020's1 (2.78)2.80

Authors

AuthorsStudies
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ansseau, M; Botte, L; Darimont, P; De Nayer, A; De Wilde, J; Devoitille, JM; Evrard, JL; Gérard, MA; Mertens, C; von Frenckell, R1
Clerc, G1
Ohtani, H; Sawada, Y1
Fukuchi, T; Kanemoto, K1
Hashimoto, S; Hattori, T; Kawasaki, K; Kitamura, Y; Miki, N; Mochizuki, D; Otsuka, Y; Tsujita, R; Yamada, S1
Koyama, T; Suzuki, K1
Iwamoto, Y; Yamawaki, S1
Arita, S; Morishita, S4
Matsumiya, T; Miyamoto, J; Nawa, H; Ohzeki, M; Takeda, H; Tsuji, M1
Aoki, M; Chiba, H; Harada, Y; Matsumiya, T; Nohara, J; Takeda, H; Tsuji, M1
Higuchi, H; Inoue, K; Itoh, K; Kamata, M; Ozaki, N; Suzuki, T; Takahashi, H; Yoshida, K1
Nakamura, J; Shinkai, K; Toyohira, Y; Tsutsui, M; Ueno, S; Yanagihara, N; Yoshimura, R1
Hirose, N; Kamei, J; Murasawa, H; Nakatani, A; Saitoh, A; Tatsumi, Y; Yamada, M; Yamaguchi, K1
Hazui, T; Hori, S; Matsuo, N; Miki, A; Nakano, M; Ohtani, H; Sawada, Y; Suzuki, Y; Yagi, H; Yamamoto, A1
Higuchi, H; Ito, K; Kamata, M; Naito, S; Ohkubo, T; Sato, K; Shimizu, T; Takahashi, H; Yoshida, K1
Nomura, S; Sato, Y; Shigemura, J; Yoshino, A1
Hotta, Y; Kobayashi, Y; Sugimoto, Y; Tagawa, N; Yamada, J1
Abe, H; Ikeda, T; Ishida, Y; Nakamura, T; Naono, R; Nishimori, T; Takeda, R1
Bantsiele, GB; Bentué-Ferrer, D; Bourin, M; Laviolle, B; Reymann, JM; Saïkali, S1
Aburakawa, Y; Aizawa, H; Hasebe, N; Kwak, S; Sawada, J; Yamashita, T1
Izumi, T; Ohmura, Y; Tsutsui-Kimura, I; Yamaguchi, T; Yoshida, T; Yoshioka, M1
Doe, N; Kiriyama, M; Takahashi, T1
Higuchi, H1
Nagata, T; Nakajima, T; Teo, AR; van Vliet, I; Yamada, H; Yoshimura, C1
Azuma, J; Hasegawa, R; Hiratsuka, K; Ishiwata, K; Kato, M; Kinoshita, T; Kurosawa, T; Kurose, K; Nishikawa, J; Nonen, S; Okugawa, G; Saito, Y; Wakeno, M1
Katsuyama, S; Kishikawa, Y; Nakamura, H; Sato, K; Yagi, T1
Higuchi, H; Inoue, K; Ishigooka, J; Kamata, M; Suzuki, T; Takahashi, H; Yoshida, K1
Azuma, J; Kato, M; Kinoshita, T; Nonen, S; Serretti, A; Takekita, Y; Wakeno, M1
Egashira, N; Kuwahara, J; Masuda, S; Ueda, M; Ushio, S; Yamada, T; Zukeyama, N1
Horii, A; Imai, T; Inohara, H; Kitahara, T; Morita, Y; Takahashi, K; Uno, A1
Akimoto, H; Asai, S; Hayakawa, T; Minagawa, K; Nagashima, T; Takahashi, Y1

Reviews

5 review(s) available for milnacipran and fluvoxamine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Pharmacokinetics and drug interactions of antidepressive agents].
    Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59, Issue:8

    Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents, Tricyclic; Cyclopropanes; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Fluvoxamine; Humans; Milnacipran; Selective Serotonin Reuptake Inhibitors

2001
[Pharmacokinetics and drug interaction of antidepressants and anti-manic drugs].
    Ryoikibetsu shokogun shirizu, 2003, Issue:38

    Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Antimanic Agents; Carbamazepine; Cyclopropanes; Cytochrome P-450 Enzyme System; Drug Interactions; Fluvoxamine; Humans; Isoenzymes; Lithium; Milnacipran; Paroxetine; Selective Serotonin Reuptake Inhibitors; Valproic Acid

2003
[Serotonin syndrome].
    Ryoikibetsu shokogun shirizu, 2003, Issue:38

    Topics: Adrenergic Uptake Inhibitors; Animals; Cyclopropanes; Cyproheptadine; Diagnosis, Differential; Fluvoxamine; Humans; Milnacipran; Reference Standards; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Syndrome

2003
[Prediction of antidepressant response to milnacipran and fluvoxamine using pharmacogenetical methods].
    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 2010, Volume: 30, Issue:2

    Topics: Adult; Aged; Alleles; Antidepressive Agents; Cyclopropanes; Depressive Disorder, Major; Fluvoxamine; Forecasting; Humans; Male; Middle Aged; Milnacipran; Norepinephrine Plasma Membrane Transport Proteins; Pharmacogenetics; Polymorphism, Genetic; Promoter Regions, Genetic; Racial Groups; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Young Adult

2010

Trials

5 trial(s) available for milnacipran and fluvoxamine

ArticleYear
Interest of a loading dose of milnacipran in endogenous depressive inpatients. Comparison with the standard regimen and with fluvoxamine.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1991, Volume: 1, Issue:2

    Topics: Adult; Aged; Antidepressive Agents; Cyclopropanes; Depressive Disorder; Double-Blind Method; Female; Fluvoxamine; Humans; Male; Middle Aged; Milnacipran; Psychiatric Status Rating Scales; Pulse

1991
Antidepressant efficacy and tolerability of milnacipran, a dual serotonin and noradrenaline reuptake inhibitor: a comparison with fluvoxamine.
    International clinical psychopharmacology, 2001, Volume: 16, Issue:3

    Topics: Adult; Aged; Antidepressive Agents; Cyclopropanes; Depressive Disorder, Major; Female; Fluvoxamine; Humans; Male; Middle Aged; Milnacipran; Treatment Outcome

2001
Differential effects of fluvoxamine, paroxetine and milnacipran for depression, especially with regard to age.
    Human psychopharmacology, 2004, Volume: 19, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Chi-Square Distribution; Cohort Studies; Cyclopropanes; Depression; Female; Fluvoxamine; Humans; Male; Middle Aged; Milnacipran; Paroxetine; Psychiatric Status Rating Scales; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

2004
The G196A polymorphism of the brain-derived neurotrophic factor gene and the antidepressant effect of milnacipran and fluvoxamine.
    Journal of psychopharmacology (Oxford, England), 2007, Volume: 21, Issue:6

    Topics: Adult; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Cyclopropanes; Depression; Exons; Female; Fluvoxamine; Gene Frequency; Genotype; Humans; Male; Middle Aged; Milnacipran; Patient Compliance; Patient Selection; Phenotype; Polymorphism, Genetic; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Time Factors; Treatment Outcome

2007
Genetic variants in combination with early partial improvement as a clinical utility predictor of treatment outcome in major depressive disorder: the result of two pooled RCTs.
    Translational psychiatry, 2015, Feb-24, Volume: 5

    Topics: Age Factors; Antidepressive Agents; Antidepressive Agents, Second-Generation; Cyclopropanes; Depressive Disorder, Major; Female; Fibroblast Growth Factors; Fluvoxamine; Humans; Japan; Male; Middle Aged; Milnacipran; Paroxetine; Psychiatric Status Rating Scales; Receptor, Serotonin, 5-HT1A; Receptors, Adrenergic, alpha-2; Serotonin Plasma Membrane Transport Proteins; Sex Factors; Treatment Outcome

2015

Other Studies

26 other study(ies) available for milnacipran and fluvoxamine

ArticleYear
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Differential effects of milnacipran and fluvoxamine, especially in patients with severe depression and agitated depression: a case-control study.
    International clinical psychopharmacology, 2002, Volume: 17, Issue:2

    Topics: Adult; Antidepressive Agents, Second-Generation; Case-Control Studies; Cyclopropanes; Depressive Disorder; Female; Fluvoxamine; Humans; Individuality; Male; Milnacipran; Patient Dropouts; Psychiatric Status Rating Scales; Psychomotor Agitation

2002
Neurochemical and behavioural characterization of milnacipran, a serotonin and noradrenaline reuptake inhibitor in rats.
    Psychopharmacology, 2002, Volume: 162, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Behavior, Animal; Binding, Competitive; Brain Chemistry; Conditioning, Psychological; Cyclopropanes; Dose-Response Relationship, Drug; Fear; Fluoxetine; Fluvoxamine; Imipramine; Male; Maprotiline; Microdialysis; Milnacipran; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Norepinephrine; Prefrontal Cortex; Radioligand Assay; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Cell Surface; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Swimming; Synaptosomes; Time Factors

2002
Differential period of onset of action of fluvoxamine, paroxetine and milnacipran for depression.
    Human psychopharmacology, 2003, Volume: 18, Issue:6

    Topics: Antidepressive Agents; Bipolar Disorder; Cyclopropanes; Depressive Disorder, Major; Female; Fluvoxamine; Humans; Male; Middle Aged; Milnacipran; Outpatients; Paroxetine; Psychiatric Status Rating Scales; Retrospective Studies; Time Factors; Treatment Outcome

2003
Differential effects of milnacipran, fluvoxamine and paroxetine for depression, especially in gender.
    European psychiatry : the journal of the Association of European Psychiatrists, 2003, Volume: 18, Issue:8

    Topics: Adrenergic Uptake Inhibitors; Adult; Antidepressive Agents, Second-Generation; Bipolar Disorder; Cohort Studies; Cyclopropanes; Depressive Disorder, Major; Female; Fluvoxamine; Humans; Male; Middle Aged; Milnacipran; Paroxetine; Personality Inventory; Psychometrics; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Sex Factors; Treatment Outcome

2003
Differential effects of milnacipran, fluvoxamine and paroxetine for inhibited and agitated depression.
    European psychiatry : the journal of the Association of European Psychiatrists, 2004, Volume: 19, Issue:7

    Topics: Cohort Studies; Cyclopropanes; Depression; Drug Administration Schedule; Fluvoxamine; Humans; Milnacipran; Paroxetine; Psychomotor Agitation; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Surveys and Questionnaires

2004
Characterization of the anxiolytic-like effects of fluvoxamine, milnacipran and risperidone in mice using the conditioned fear stress paradigm.
    European journal of pharmacology, 2004, Nov-03, Volume: 504, Issue:1-2

    Topics: Animals; Anti-Anxiety Agents; Conditioning, Psychological; Cyclopropanes; Dose-Response Relationship, Drug; Fear; Fluvoxamine; Male; Mice; Mice, Inbred ICR; Milnacipran; Risperidone; Serotonin Antagonists; Stress, Physiological

2004
Antidepressants enhance the antinociceptive effects of carbamazepine in the acetic acid-induced writhing test in mice.
    European journal of pharmacology, 2006, Nov-21, Volume: 550, Issue:1-3

    Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Carbamazepine; Cyclopropanes; Fluvoxamine; Imipramine; Male; Mice; Mice, Inbred ICR; Milnacipran; Pain; Pain Measurement

2006
Stimulation of catecholamine synthesis via activation of p44/42 MAPK in cultured bovine adrenal medullary cells by milnacipran.
    Naunyn-Schmiedeberg's archives of pharmacology, 2007, Volume: 375, Issue:1

    Topics: Adrenal Medulla; Animals; Antidepressive Agents; Butadienes; Catecholamines; Cattle; Cells, Cultured; Cyclopropanes; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Enzyme Activation; Fluvoxamine; Milnacipran; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Paroxetine; Phosphorylation; Protein Kinase Inhibitors; Selective Serotonin Reuptake Inhibitors; Time Factors; Tyrosine; Tyrosine 3-Monooxygenase

2007
Effects of milnacipran and fluvoxamine on hyperemotional behaviors and the loss of tryptophan hydroxylase-positive cells in olfactory bulbectomized rats.
    Psychopharmacology, 2007, Volume: 191, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Animals; Behavior, Animal; Cyclopropanes; Dose-Response Relationship, Drug; Emotions; Fluvoxamine; Male; Milnacipran; Motor Activity; Neurons; Olfactory Bulb; Raphe Nuclei; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Time Factors; Tryptophan Hydroxylase

2007
Piloerection induced by replacing fluvoxamine with milnacipran.
    British journal of clinical pharmacology, 2007, Volume: 63, Issue:6

    Topics: Adult; Antidepressive Agents; Cyclopropanes; Female; Fluvoxamine; Humans; Imipramine; Milnacipran; Models, Biological; Norepinephrine; Panic Disorder; Piloerection

2007
Gender differences in the clinical effects of fluvoxamine and milnacipran in Japanese major depressive patients.
    Psychiatry and clinical neurosciences, 2007, Volume: 61, Issue:4

    Topics: Aging; Antidepressive Agents, Second-Generation; Cyclopropanes; Data Collection; Depressive Disorder, Major; Female; Fluvoxamine; Humans; Japan; Male; Menopause; Middle Aged; Milnacipran; Psychiatric Status Rating Scales; Sex Characteristics

2007
Patient satisfaction with antidepressants: an Internet-based study.
    Journal of affective disorders, 2008, Volume: 107, Issue:1-3

    Topics: Analysis of Variance; Antidepressive Agents; Antidepressive Agents, Tricyclic; Cyclopropanes; Data Collection; Depressive Disorder, Major; Fluvoxamine; Humans; Internet; Japan; Logistic Models; Milnacipran; Paroxetine; Patient Satisfaction; Selective Serotonin Reuptake Inhibitors; Surveys and Questionnaires

2008
Effects of the serotonin and noradrenaline reuptake inhibitor (SNRI) milnacipran on marble burying behavior in mice.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:12

    Topics: Adrenergic Uptake Inhibitors; Animals; Behavior, Animal; Cyclopropanes; Fluvoxamine; Male; Mice; Mice, Inbred ICR; Milnacipran; Motor Activity; Obsessive-Compulsive Disorder; Selective Serotonin Reuptake Inhibitors

2007
Effects of intrathecal administration of newer antidepressants on mechanical allodynia in rat models of neuropathic pain.
    Neuroscience research, 2009, Volume: 63, Issue:1

    Topics: Analgesics; Animals; Antidepressive Agents; Cyclopropanes; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Fluvoxamine; Hyperalgesia; Injections, Spinal; Male; Milnacipran; Pain Threshold; Paroxetine; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Selective Serotonin Reuptake Inhibitors; Serotonin; Spinal Cord

2009
Behavioral effects of four antidepressants on an ischemic rat model of emotional disturbances.
    Behavioural brain research, 2009, Aug-12, Volume: 201, Issue:2

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Anxiety Disorders; Behavior, Animal; Brain Ischemia; Cyclopropanes; Depressive Disorder; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Fluvoxamine; Hippocampus; Imipramine; Immobility Response, Tonic; Male; Milnacipran; Motor Activity; Rats; Rats, Wistar

2009
Effects of antidepressants on GluR2 Q/R site-RNA editing in modified HeLa cell line.
    Neuroscience research, 2009, Volume: 64, Issue:3

    Topics: Adenosine Deaminase; Amitriptyline; Amyotrophic Lateral Sclerosis; Antidepressive Agents; Arginine; Cyclopropanes; Desipramine; Fluoxetine; Fluvoxamine; Glutamine; HeLa Cells; Humans; Imipramine; Milnacipran; Morpholines; Paroxetine; Reboxetine; Receptors, AMPA; RNA Editing; RNA-Binding Proteins; RNA, Messenger

2009
The effects of serotonin and/or noradrenaline reuptake inhibitors on impulsive-like action assessed by the three-choice serial reaction time task: a simple and valid model of impulsive action using rats.
    Behavioural pharmacology, 2009, Volume: 20, Issue:5-6

    Topics: Adrenergic Uptake Inhibitors; Animals; Atomoxetine Hydrochloride; Behavior, Animal; Choice Behavior; Cyclopropanes; Disease Models, Animal; Dose-Response Relationship, Drug; Fluvoxamine; Impulsive Behavior; Male; Milnacipran; Nicotine; Nicotinic Agonists; Propylamines; Rats; Rats, Wistar; Reaction Time; Reproducibility of Results; Selective Serotonin Reuptake Inhibitors

2009
Behavioral despair during a water maze learning task in mice.
    Experimental animals, 2010, Volume: 59, Issue:2

    Topics: Animals; Behavior, Animal; Cyclopropanes; Depression; Disease Models, Animal; Escape Reaction; Fluvoxamine; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Milnacipran; Selective Serotonin Reuptake Inhibitors; Swimming

2010
Comorbid social withdrawal (hikikomori) in outpatients with social anxiety disorder: clinical characteristics and treatment response in a case series.
    The International journal of social psychiatry, 2013, Volume: 59, Issue:1

    Topics: Adolescent; Adult; Anti-Anxiety Agents; Cognitive Behavioral Therapy; Combined Modality Therapy; Comorbidity; Cyclopropanes; Diagnostic and Statistical Manual of Mental Disorders; Female; Fluvoxamine; Humans; Interview, Psychological; Japan; Male; Milnacipran; Obsessive-Compulsive Disorder; Paroxetine; Phobic Disorders; Psychotherapy, Group; Reactive Attachment Disorder; Retrospective Studies; Social Isolation; Treatment Outcome; Young Adult

2013
Genome-wide association study of SSRI/SNRI-induced sexual dysfunction in a Japanese cohort with major depression.
    Psychiatry research, 2012, Aug-15, Volume: 198, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Aged, 80 and over; Asian People; Cohort Studies; Cyclopropanes; Depressive Disorder, Major; Female; Fluvoxamine; Genome-Wide Association Study; Genotype; GPI-Linked Proteins; Humans; Male; Middle Aged; Milnacipran; Neural Cell Adhesion Molecules; Paroxetine; Polymorphism, Single Nucleotide; Selective Serotonin Reuptake Inhibitors; Sexual Dysfunction, Physiological; Sexual Dysfunctions, Psychological

2012
Effects of repeated milnacipran and fluvoxamine treatment on mechanical allodynia in a mouse paclitaxel-induced neuropathic pain model.
    Biomedical research (Tokyo, Japan), 2013, Volume: 34, Issue:2

    Topics: Animals; Cyclopropanes; Disease Models, Animal; Fluvoxamine; Hyperalgesia; Male; Mice; Milnacipran; Neuralgia; Paclitaxel

2013
Bcl1 polymorphism of the glucocorticoid receptor gene and treatment response to milnacipran and fluvoxamine in Japanese patients with depression.
    Neuropsychobiology, 2014, Volume: 70, Issue:3

    Topics: Antidepressive Agents; Asian People; Cyclin D1; Cyclopropanes; Depressive Disorder, Major; Female; Fluvoxamine; Genotype; Humans; Male; Middle Aged; Milnacipran; Polymorphism, Single Nucleotide; Receptors, Glucocorticoid; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Treatment Outcome

2014
Comparison of the Anti-tumor Effects of Selective Serotonin Reuptake Inhibitors as Well as Serotonin and Norepinephrine Reuptake Inhibitors in Human Hepatocellular Carcinoma Cells.
    Biological & pharmaceutical bulletin, 2015, Volume: 38, Issue:9

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Survival; Citalopram; Cyclopropanes; Duloxetine Hydrochloride; Fluvoxamine; Hep G2 Cells; Humans; Liver Neoplasms; Milnacipran; Paroxetine; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Sertraline

2015
Psychiatric comorbidities and use of milnacipran in patients with chronic dizziness.
    Journal of vestibular research : equilibrium & orientation, 2016, 07-02, Volume: 26, Issue:3

    Topics: Anxiety Disorders; Chronic Disease; Comorbidity; Cyclopropanes; Depressive Disorder; Dizziness; Female; Fluvoxamine; Humans; Male; Mental Disorders; Middle Aged; Milnacipran; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors

2016
Identifying Antidepressants Less Likely to Cause Hyponatremia: Triangulation of Retrospective Cohort, Disproportionality, and Pharmacodynamic Studies.
    Clinical pharmacology and therapeutics, 2022, Volume: 111, Issue:6

    Topics: Antidepressive Agents; Cohort Studies; Fluvoxamine; Humans; Hyponatremia; Milnacipran; Mirtazapine; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Sodium

2022