Page last updated: 2024-08-23

miglustat and isofagomine

miglustat has been researched along with isofagomine in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Blériot, Y; Davies, GJ; Dumon, C; Gilbert, HJ; Gratien, J; Heck, MP; Morland, C; Offen, WA; Smith, NL; Stick, RV; Tailford, LE; Vasella, A1
Allman, S; Butters, TD; Jensen, HH; Rasmussen, TS; Twigg, G1
Benjamin, ER; Boyd, RE; Khanna, R; Lee, G; Rybczynski, P; Valenzano, KJ; Wustman, BA1
Fleet, GWJ; Jia, YM; Kato, A; Kise, M; Li, YX; Shimadate, Y; Wang, JZ; Yu, CY1
Chung, S; Do, H; Kornfeld, S; Lee, WS; Pine, CW; Steet, R1
Kaminsky, P; Lidove, O1

Reviews

2 review(s) available for miglustat and isofagomine

ArticleYear
Pharmacological chaperones as therapeutics for lysosomal storage diseases.
    Journal of medicinal chemistry, 2013, Apr-11, Volume: 56, Issue:7

    Topics: Cell Line; Glycolipids; Humans; Lysosomal Storage Diseases; Molecular Chaperones; Structure-Activity Relationship

2013
[Current therapeutic strategies in lysosomal disorders].
    Presse medicale (Paris, France : 1983), 2014, Volume: 43, Issue:11

    Topics: 1-Deoxynojirimycin; Codon, Nonsense; Codon, Terminator; Cystine Depleting Agents; Enzyme Inhibitors; Enzyme Replacement Therapy; Gene Expression Regulation; Hematopoietic Stem Cell Transplantation; Humans; Imino Pyranoses; Lysosomal Storage Diseases; Mutant Proteins; Renal Insufficiency

2014

Other Studies

4 other study(ies) available for miglustat and isofagomine

ArticleYear
Structural and biochemical evidence for a boat-like transition state in beta-mannosidases.
    Nature chemical biology, 2008, Volume: 4, Issue:5

    Topics: beta-Mannosidase; Enzyme Inhibitors; Hydrolysis; Molecular Mimicry; Protein Conformation

2008
Synthesis of N-alkylated noeurostegines and evaluation of their potential as treatment for Gaucher's disease.
    Bioorganic & medicinal chemistry letters, 2011, Mar-01, Volume: 21, Issue:5

    Topics: Enzyme Assays; Gaucher Disease; Glucosylceramidase; Humans; Inhibitory Concentration 50; Nortropanes

2011
trans, trans-2-C-Aryl-3,4-dihydroxypyrrolidines as potent and selective β-glucosidase inhibitors: Pharmacological chaperones for Gaucher disease.
    European journal of medicinal chemistry, 2022, Aug-05, Volume: 238

    Topics: beta-Glucosidase; Enzyme Inhibitors; Gaucher Disease; Glucosylceramidase; Humans; Molecular Docking Simulation; Pyrrolidines

2022
Selective action of the iminosugar isofagomine, a pharmacological chaperone for mutant forms of acid-beta-glucosidase.
    Biochemical pharmacology, 2007, May-01, Volume: 73, Issue:9

    Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Cell Proliferation; Cells, Cultured; Disaccharidases; Gaucher Disease; Glucosylceramidase; Glucosyltransferases; Glycoside Hydrolases; Humans; Imino Pyranoses; Lysosomes; Mutation; Oligosaccharides; Piperidines

2007