Page last updated: 2024-09-05

migalastat and sphingosine

migalastat has been researched along with sphingosine in 2 studies

Compound Research Comparison

Studies (migalastat)	Trials (migalastat)	Recent Studies (post-2010) (migalastat)	Studies (sphingosine)	Trials (sphingosine)	Recent Studies (post-2010) (sphingosine)
143	14	89	8,325	117	3,459

Protein Interaction Comparison

Protein	Taxonomy	sphingosine (IC50)
ubiquitin-conjugating enzyme E2 N	Homo sapiens (human)	6.3125
cAMP-dependent protein kinase catalytic subunit alpha	Rattus norvegicus (Norway rat)	0.098
Sphingosine kinase 2	Homo sapiens (human)	1.56
Sphingosine kinase 1	Homo sapiens (human)	3.86

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	1 (50.00)	2.80

Authors

Authors	Studies
Benjamin, ER; Boudes, P; Brignol, N; Chang, HH; Fuller, M; Germain, DP; Giugliani, R; Hughes, DA; Khanna, R; Lockhart, DJ; Mehta, A; Nicholls, K; Sitaraman, SA; Soska, R; Valenzano, KJ; Young-Gqamana, B	1
Andreotti, G; Bräuer, AU; Cimmaruta, C; Citro, V; Cozma, C; Cubellis, MV; Ernst, M; Fuellen, G; Giese, AK; Haake, LR; Hermann, A; Knospe, AM; Koczan, D; Lukas, J; Rolfs, A; Seemann, S; Struckmann, S	1

Other Studies

2 other study(ies) available for migalastat and sphingosine

Article	Year
Migalastat HCl reduces globotriaosylsphingosine (lyso-Gb3) in Fabry transgenic mice and in the plasma of Fabry patients. PloS one, 2013, Volume: 8, Issue:3 Topics: 1-Deoxynojirimycin; Administration, Oral; alpha-Galactosidase; Animals; Fabry Disease; Glycolipids; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Reproducibility of Results; Sphingolipids; Sphingosine; Trihexosylceramides	2013
Proteostasis regulators modulate proteasomal activity and gene expression to attenuate multiple phenotypes in Fabry disease. The Biochemical journal, 2020, 01-31, Volume: 477, Issue:2 Topics: 1-Deoxynojirimycin; alpha-Galactosidase; Biomarkers; Endoplasmic Reticulum; Fabry Disease; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Lysosomal Storage Diseases; Lysosomes; Mutation, Missense; Proteasome Endopeptidase Complex; Protein Transport; Proteostasis; Sphingosine	2020

Article

Year

Migalastat HCl reduces globotriaosylsphingosine (lyso-Gb3) in Fabry transgenic mice and in the plasma of Fabry patients.

PloS one, 2013, Volume: 8, Issue:3

Topics: 1-Deoxynojirimycin; Administration, Oral; alpha-Galactosidase; Animals; Fabry Disease; Glycolipids; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Reproducibility of Results; Sphingolipids; Sphingosine; Trihexosylceramides

2013

Proteostasis regulators modulate proteasomal activity and gene expression to attenuate multiple phenotypes in Fabry disease.

The Biochemical journal, 2020, 01-31, Volume: 477, Issue:2

Topics: 1-Deoxynojirimycin; alpha-Galactosidase; Biomarkers; Endoplasmic Reticulum; Fabry Disease; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Lysosomal Storage Diseases; Lysosomes; Mutation, Missense; Proteasome Endopeptidase Complex; Protein Transport; Proteostasis; Sphingosine

2020