mifepristone has been researched along with zk 112993 in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.17) | 18.7374 |
| 1990's | 21 (87.50) | 18.2507 |
| 2000's | 2 (8.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gehring, S; Kühnel, W; Michna, H; Nishino, Y; Schneider, MR | 1 |
| el Etreby, MF; Louton, T; Michna, H; Nishino, Y; Schneider, MR | 1 |
| el Etreby, MF; McGuire, WL; Michna, H; Nishino, Y; Schneider, M | 1 |
| el Etreby, MF; Michna, H; Nishino, Y; Schneider, MR | 1 |
| Chen, D; Mikulits, W; Müllner, EW | 1 |
| Chwalisz, K; Elger, W; Osawa, Y; Shimizu, Y; Yarborough, CP | 1 |
| Altmann, M; Beck, CA; DeMarzo, A; Edwards, DP; Weigel, NL; Zhang, Y | 1 |
| Clemm, DL; Macy, BL; McDonnell, DP; Santiso-Mere, D | 1 |
| Morales, AJ; Murphy, AA; Parthasarathy, S | 1 |
| Groshong, SD; Horwitz, KB; Miller, LA; Powell, RL; Sartorius, CA; Takimoto, GS; Tung, L | 1 |
| Hoeffler, JP; Horwitz, KB; Mohamed, MK; Takimoto, GS; Tung, L | 1 |
| Goldman, ME; McDonnell, DP; Shahbaz, MM; Vegeto, E | 1 |
| Horwitz, KB; Sartorius, CA; Takimoto, GS; Tung, L | 1 |
| Beck, CA; Edwards, DP; Moyer, ML; Nordeen, SK; Weigel, NL | 1 |
| Dickson, RB; Lippman, ME; Shi, YE; Sobel, ME; Thompson, EW; Torri, J; Yamada, Y; Yieh, L | 1 |
| Kühnel, W; Michna, H; Rumpel, E | 1 |
| Archer, TK; Mymryk, JS | 1 |
| Baker, C; Hawkins, P; Norris, B; Quinn, PG; Sheridan, PL; Wei, LL | 1 |
| Pinter, J; Thomas, P | 1 |
| Gurpide, E; Markiewicz, L | 1 |
| Borras, M; Lacroix, M; Leclercq, G; Legros, N | 1 |
| Schubert, AK | 1 |
| Malkapuram, S; Murphy, AA; Parthasarathy, S; Santanam, N; Sidell, N; Zhou, MH | 1 |
| Engström, C; Jaeger, R; Sager, G; Ørbo, A | 1 |
1 review(s) available for mifepristone and zk 112993
| Article | Year |
|---|---|
Definition of the critical cellular components which distinguish between hormone and antihormone activated progesterone receptor.
Topics: DNA-Binding Proteins; Gene Expression Regulation; Humans; Macromolecular Substances; Mifepristone; Progesterone; Promoter Regions, Genetic; Receptors, Progesterone; Receptors, Steroid; Repressor Proteins; Signal Transduction; Structure-Activity Relationship; Transcription, Genetic; Transcriptional Activation | 1995 |
23 other study(ies) available for mifepristone and zk 112993
| Article | Year |
|---|---|
The antitumor potency of progesterone antagonists is due to their differentiation potential.
Topics: Animals; Antineoplastic Agents; Cell Differentiation; Gonanes; Mammary Neoplasms, Experimental; Mice; Mifepristone; Progesterone; Rats | 1992 |
A bioassay for the evaluation of antiproliferative potencies of progesterone antagonists.
Topics: Animals; DNA; Female; Gonanes; Mammary Glands, Animal; Mifepristone; Organ Size; Progesterone; Rats; Rats, Inbred Strains; RNA | 1991 |
Progesterone antagonists block the growth of experimental mammary tumors in G0/G1.
Topics: Animals; Antineoplastic Agents; Cell Division; Female; G1 Phase; Gonanes; Mammary Neoplasms, Experimental; Mifepristone; Progesterone; Rats; Rats, Inbred Strains; Resting Phase, Cell Cycle | 1990 |
The antitumor mechanism of progesterone antagonists is a receptor mediated antiproliferative effect by induction of terminal cell death.
Topics: Animals; Antineoplastic Agents; Cell Division; Cell Line; Cell Survival; Estradiol; Female; Gonanes; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Mifepristone; Ovariectomy; Progesterone; Tumor Cells, Cultured | 1989 |
Dexamethasone inducible gene expression optimised by glucocorticoid antagonists.
Topics: 3T3 Cells; Animals; Blotting, Northern; Dexamethasone; DNA, Viral; Gene Expression; Glucocorticoids; Mammary Tumor Virus, Mouse; Mice; Mifepristone; Repetitive Sequences, Nucleic Acid; Transfection | 1995 |
Inhibition of aromatase activity in human placental microsomes by 13-retro-antiprogestins.
Topics: Aromatase Inhibitors; Estrenes; Estrone; Female; Gonanes; Humans; Microsomes; Mifepristone; Placenta; Pregnancy; Progestins | 1995 |
Progesterone receptor and the mechanism of action of progesterone antagonists.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; DNA-Binding Proteins; Estrenes; Gonanes; Humans; In Vitro Techniques; Mifepristone; Progesterone; Promegestone; Protein Binding; Protein Conformation; Receptors, Progesterone; Signal Transduction; Transcription Factors; Transcription, Genetic | 1995 |
Antioxidant: a new role for RU-486 and related compounds.
Topics: Animals; Antioxidants; Lipoproteins, LDL; Mice; Mifepristone; Oxidation-Reduction | 1994 |
New T47D breast cancer cell lines for the independent study of progesterone B- and A-receptors: only antiprogestin-occupied B-receptors are switched to transcriptional agonists by cAMP.
Topics: Base Sequence; Breast Neoplasms; Cyclic AMP; Female; Gonanes; Humans; Mifepristone; Molecular Sequence Data; Progestins; Receptors, Progesterone; Transcription, Genetic; Tumor Cells, Cultured | 1994 |
Antagonist-occupied human progesterone B-receptors activate transcription without binding to progesterone response elements and are dominantly inhibited by A-receptors.
Topics: Binding Sites; DNA; Genes, fos; Genes, jun; Genes, Reporter; Gonanes; HeLa Cells; Humans; Leucine Zippers; Mifepristone; Phenotype; Progesterone; Promoter Regions, Genetic; Receptors, Progesterone; Recombinant Fusion Proteins; Transcription, Genetic; Transfection | 1993 |
The human progesterone receptor A-form functions as a transcriptional modulator of mineralocorticoid receptor transcriptional activity.
Topics: Animals; Cells, Cultured; Gonanes; Haplorhini; Humans; Mifepristone; Mineralocorticoid Receptor Antagonists; Molecular Conformation; Progestins; Receptors, Mineralocorticoid; Receptors, Progesterone; Repressor Proteins; Transcription, Genetic | 1994 |
Antagonist-occupied human progesterone receptors bound to DNA are functionally switched to transcriptional agonists by cAMP.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Antineoplastic Agents; Base Sequence; beta-Galactosidase; Breast Neoplasms; Cell Line; Chloramphenicol O-Acetyltransferase; Cyclic AMP; DNA-Binding Proteins; Female; Gonanes; Humans; Mifepristone; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phosphates; Progesterone; Promegestone; Receptors, Progesterone; Recombinant Proteins; Transcription Factors; Transfection; Tumor Cells, Cultured | 1993 |
The progesterone antagonist RU486 acquires agonist activity upon stimulation of cAMP signaling pathways.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cyclic AMP; DNA-Binding Proteins; Gene Expression Regulation, Viral; Humans; In Vitro Techniques; Mammary Tumor Virus, Mouse; Mifepristone; Progesterone; Receptors, Progesterone; Signal Transduction; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Expression of 67 kDa laminin receptor in human breast cancer cells: regulation by progestins.
Topics: Analysis of Variance; Animals; Antineoplastic Agents; Basement Membrane; Blotting, Western; Breast Neoplasms; Cell Adhesion; Female; Fibronectins; Humans; Laminin; Mice; Mice, Nude; Mifepristone; Neoplasm Metastasis; Promegestone; Receptors, Laminin; Reproducibility of Results; Tumor Cells, Cultured; Up-Regulation | 1993 |
Morphology of the rat uterus after long-term treatment with progesterone antagonists.
Topics: Animals; Cytoplasmic Granules; Endometrium; Epithelial Cells; Epithelium; Female; Gonanes; Microscopy, Electron; Mifepristone; Progesterone; Rats; Rats, Sprague-Dawley; Uterus | 1993 |
Influence of hormone antagonists on chromatin remodeling and transcription factor binding to the mouse mammary tumor virus promoter in vivo.
Topics: Animals; Binding, Competitive; Chromatin; Dexamethasone; Glucocorticoids; Gonanes; Hormone Antagonists; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mifepristone; Promoter Regions, Genetic; Receptors, Glucocorticoid; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 1995 |
An amino-terminal truncated progesterone receptor isoform, PRc, enhances progestin-induced transcriptional activity.
Topics: Antineoplastic Agents; Breast Neoplasms; Enhancer Elements, Genetic; Gonanes; HeLa Cells; Hormone Antagonists; Humans; Methionine; Mifepristone; Progesterone Congeners; Progestins; Promegestone; Protein Biosynthesis; Receptors, Progesterone; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1996 |
The ovarian progestogen receptor in the spotted seatrout, Cynoscion nebulosus, demonstrates steroid specificity different from progesterone receptors in other vertebrates.
Topics: Adrenal Cortex Hormones; Animals; Atrazine; Binding, Competitive; Estradiol; Female; Hormone Antagonists; Hormones; Hydrocarbons, Chlorinated; Insecticides; Mifepristone; Ovary; Progesterone; Receptors, Progesterone; Solvents; Steroids; Structure-Activity Relationship; Substrate Specificity; Trout; Vertebrates; Water Pollutants | 1997 |
Estrogenic and progestagenic activities of physiologic and synthetic androgens, as measured by in vitro bioassays.
Topics: Adenocarcinoma; Alkaline Phosphatase; Androgen Antagonists; Androgens; Breast Neoplasms; Cyproterone Acetate; Endometrial Neoplasms; Estradiol; Estrogen Antagonists; Female; Flutamide; Gonanes; Humans; Mifepristone; Polyunsaturated Alkamides; Progestins; Tamoxifen; Testosterone; Testosterone Congeners; Tumor Cells, Cultured | 1997 |
Estrogen receptor-negative/progesterone receptor-positive Evsa-T mammary tumor cells: a model for assessing the biological property of this peculiar phenotype of breast cancers.
Topics: Breast Neoplasms; Cell Division; Cytosol; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Gonanes; Hormone Antagonists; Humans; Mifepristone; Pregnenediones; Progestins; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured | 1997 |
[Effects of progesterone antagonists on the eosinophilic granulocytes in the rat uterus].
Topics: Animals; Endometrium; Eosinophils; Estrogens; Estrone; Female; Gonanes; Hormone Antagonists; Mifepristone; Myometrium; Ovariectomy; Progesterone; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sexual Maturation; Uterus | 1998 |
RU486-induced growth inhibition of human endometrial cells.
Topics: Antioxidants; Cell Division; Cell Line; Endometrium; Female; Hormone Antagonists; Humans; Mifepristone; Pregnatrienes | 2000 |
Non-genomic effects of progestins--inhibition of cell growth and increased intracellular levels of cyclic nucleotides.
Topics: Antineoplastic Agents; Cell Division; Cell Line, Transformed; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Gonanes; Hormone Antagonists; Humans; Mifepristone; Progestins; Radioimmunoassay; Receptors, Steroid; Time Factors | 2003 |