Page last updated: 2024-08-23

mifepristone and telapristone acetate

mifepristone has been researched along with telapristone acetate in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (41.67)29.6817
2010's6 (50.00)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Attardi, BJ; Blye, RP; Burgenson, J; Hild, SA; Reel, JR1
Attardi, BJ; Burgenson, J; Hild, SA; Reel, JR1
Christov, K; Mehta, R; Wiehle, RD1
Leo, JC; Lin, VC1
Spitz, IM1
Beckley, EH; Finn, DA; Scibelli, AC1
Manyonda, I; Talaulikar, VS1
Gamarra-Luques, CD; Goyeneche, AA; Hapon, MB; Telleria, CM1
Abraham, T; Arian, SE; Bartels, CB; Cayton, KC; Chuong, FS; Holthouser, K; Segars, JH1
Choi, MR; Christov, K; Ivancic, D; Khan, SA; Lee, O1
Belland, L; Leyland, N; Murji, A; Singh, SS; von Riedemann, S1
Bosland, MC; Clare, SE; Helenowski, I; Hosseini, O; Khan, SA; Kim, JJ; Lee, O; Patel, P; Schipma, MJ; Shidfar, A; Wang, M; Xuei, X1

Reviews

4 review(s) available for mifepristone and telapristone acetate

ArticleYear
Clinical utility of progesterone receptor modulators and their effect on the endometrium.
    Current opinion in obstetrics & gynecology, 2009, Volume: 21, Issue:4

    Topics: Drug Administration Schedule; Endometriosis; Endometrium; Estrenes; Female; Hormone Antagonists; Humans; Leiomyoma; Mifepristone; Norpregnadienes; Oximes; Randomized Controlled Trials as Topic; Receptors, Progesterone; Time Factors; Uterine Neoplasms

2009
Progesterone and progesterone receptor modulators in the management of symptomatic uterine fibroids.
    European journal of obstetrics, gynecology, and reproductive biology, 2012, Volume: 165, Issue:2

    Topics: Endometrium; Estrenes; Female; Hormone Antagonists; Humans; Hyperplasia; Intrauterine Devices, Medicated; Leiomyoma; Levonorgestrel; Mifepristone; Norpregnadienes; Oximes; Receptors, Progesterone

2012
An Evidence-based Approach to the Medical Management of Fibroids: A Systematic Review.
    Clinical obstetrics and gynecology, 2016, Volume: 59, Issue:1

    Topics: Androgens; Aromatase Inhibitors; Contraceptive Agents, Female; Contraceptives, Oral, Combined; Curcumin; Delayed-Action Preparations; Drugs, Chinese Herbal; Estradiol; Estrenes; Estrogen Receptor Antagonists; Evidence-Based Medicine; Female; Fulvestrant; Gonadotropin-Releasing Hormone; Hormone Antagonists; Humans; Intrauterine Devices, Medicated; Leiomyoma; Levonorgestrel; Medroxyprogesterone Acetate; Mifepristone; Neoadjuvant Therapy; Norpregnadienes; Oximes; Plant Extracts; Receptors, Progesterone; Selective Estrogen Receptor Modulators; Tea; Uterine Myomectomy; Uterine Neoplasms; Vitamin D; Vitamins

2016
The past, present, and future of selective progesterone receptor modulators in the management of uterine fibroids.
    American journal of obstetrics and gynecology, 2018, Volume: 218, Issue:6

    Topics: Contraceptive Agents, Female; Disease Management; Estrenes; Female; Forecasting; Humans; Leiomyoma; Mifepristone; Norpregnadienes; Oximes; Population Growth; Receptors, Progesterone; Steroids; Uterine Neoplasms

2018

Other Studies

8 other study(ies) available for mifepristone and telapristone acetate

ArticleYear
CDB-4124 and its putative monodemethylated metabolite, CDB-4453, are potent antiprogestins with reduced antiglucocorticoid activity: in vitro comparison to mifepristone and CDB-2914.
    Molecular and cellular endocrinology, 2002, Feb-25, Volume: 188, Issue:1-2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alkaline Phosphatase; Animals; Binding, Competitive; Enzyme Induction; Hormone Antagonists; Luciferases; Mifepristone; Norpregnadienes; Plasmids; Progestins; Rabbits; Rats; Receptors, Androgen; Receptors, Glucocorticoid; Receptors, Progesterone; Recombinant Proteins; Transcriptional Activation; Transfection; Tumor Cells, Cultured

2002
In vitro antiprogestational/antiglucocorticoid activity and progestin and glucocorticoid receptor binding of the putative metabolites and synthetic derivatives of CDB-2914, CDB-4124, and mifepristone.
    The Journal of steroid biochemistry and molecular biology, 2004, Volume: 88, Issue:3

    Topics: Alkaline Phosphatase; Animals; Cell Line; Enzyme Induction; Hormone Antagonists; Mifepristone; Norpregnadienes; Progestins; Protein Binding; Rabbits; Receptors, Glucocorticoid; Receptors, Progesterone

2004
Anti-progestins suppress the growth of established tumors induced by 7,12-dimethylbenz(a)anthracene: comparison between RU486 and a new 21-substituted-19-nor-progestin.
    Oncology reports, 2007, Volume: 18, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Proliferation; Disease Progression; Female; Hormone Antagonists; Mammary Neoplasms, Experimental; Mifepristone; Norpregnadienes; Progesterone Congeners; Progestins; Rats; Rats, Sprague-Dawley

2007
The activities of progesterone receptor isoform A and B are differentially modulated by their ligands in a gene-selective manner.
    International journal of cancer, 2008, Jan-01, Volume: 122, Issue:1

    Topics: Adenoviridae; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Division; Collagen; Drug Combinations; Female; Fluorescent Antibody Technique; Hormone Antagonists; Humans; Laminin; Ligands; Mifepristone; Neoplasm Invasiveness; Norpregnadienes; Polymerase Chain Reaction; Progesterone; Protein Isoforms; Proteoglycans; Receptors, Progesterone; Transfection; Tumor Cells, Cultured; Wound Healing

2008
Progesterone receptor antagonist CDB-4124 increases depression-like behavior in mice without affecting locomotor ability.
    Psychoneuroendocrinology, 2011, Volume: 36, Issue:6

    Topics: Animals; Depression; Depression, Postpartum; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Finasteride; Locomotion; Mice; Mice, Inbred DBA; Mifepristone; Norpregnadienes; Premenstrual Syndrome; Progesterone; Receptors, Progesterone; Single-Blind Method; Swimming

2011
Resistance to cisplatin and paclitaxel does not affect the sensitivity of human ovarian cancer cells to antiprogestin-induced cytotoxicity.
    Journal of ovarian research, 2014, Volume: 7

    Topics: Antineoplastic Agents, Hormonal; Cell Line, Tumor; Cell Proliferation; Cisplatin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Estrenes; Female; Furans; Hormone Antagonists; Humans; Inhibitory Concentration 50; Mifepristone; Norpregnadienes; Paclitaxel

2014
Progesterone receptor antagonism inhibits progestogen-related carcinogenesis and suppresses tumor cell proliferation.
    Cancer letters, 2016, 07-01, Volume: 376, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Antigens, CD34; Antineoplastic Agents, Hormonal; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Female; Hormone Antagonists; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Methylnitrosourea; Mice; Mifepristone; Neovascularization, Pathologic; Norpregnadienes; Progesterone; Progestins; Rats; Receptors, Estrogen; Receptors, Progesterone; Time Factors

2016
Selective progesterone receptor blockade prevents BRCA1-associated mouse mammary tumors through modulation of epithelial and stromal genes.
    Cancer letters, 2021, 11-01, Volume: 520

    Topics: Animals; BRCA1 Protein; Breast Neoplasms; Carcinogenesis; Disease Models, Animal; Epithelial Cells; Female; Humans; Mammary Glands, Animal; Mastectomy; Mice; Mifepristone; Norpregnadienes; Receptors, Progesterone; Stromal Cells; Tumor Microenvironment

2021