mifepristone has been researched along with rifampin in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 10 (58.82) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Burk, O; Eichelbaum, M; Geick, A | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Gibson, GG; Goldfarb, PS; Gray, TJ; Ogg, MS; Tarbit, M; Williams, JM | 1 |
| Goodwin, B; Hodgson, E; Liddle, C | 1 |
| Handschin, C; Hoffmann, K; Meyer, UA; Podvinec, M; Stöckli, J | 1 |
| Allen, SW; Raucy, J; Warfe, L; Yueh, MF | 1 |
| Gollapudi, S; Gupta, S; Jaidka, S | 1 |
| Mlambo, G; Sigola, LB | 1 |
| Harada, E; Ikeda, U; Ise, H; Katsuyama, Y; Maruyama, M; Matsunaga, T; Negishi, N; Ohmori, S; Sugihara, N | 1 |
| Marks, B; Raucy, J; Trubetskoy, O; Yueh, MF; Zielinski, T | 1 |
| Banks, M; Cacace, A; Connors, D; Dickinson, K; Herbst, J; Marino, A; O'Connell, J; Puglisi, J; Sinz, M; Stewart, J; Zhu, Z | 1 |
| Gui, C; Hagenbuch, B; Miao, Y; Mock, M; Stieger, B; Thompson, L; Wahlgren, B | 1 |
| Aikawa, K; Matsunaga, T; Nakamura, K; Ohmori, S; Takezawa, T | 1 |
1 review(s) available for mifepristone and rifampin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
16 other study(ies) available for mifepristone and rifampin
| Article | Year |
|---|---|
Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Dimerization; DNA; DNA Primers; Gene Expression Regulation; Humans; Intestinal Mucosa; Intestines; Molecular Sequence Data; Pregnane X Receptor; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Steroid; Retinoid X Receptors; Rifampin; Transcription Factors | 2001 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro.
Topics: Alkaline Phosphatase; beta-Naphthoflavone; Caffeine; Carbamazepine; Carcinoma, Hepatocellular; Clofibrate; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Gene Expression Regulation; Genes, Reporter; Glucocorticoids; Hormone Antagonists; Humans; Isoniazid; Mifepristone; Mixed Function Oxygenases; Phenobarbital; Phenylbutazone; Phenytoin; Receptors, Glucocorticoid; Recombinant Proteins; Rifampin; Tumor Cells, Cultured; Xenobiotics | 1999 |
The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module.
Topics: 3T3 Cells; Animals; Antibiotics, Antitubercular; Base Sequence; COS Cells; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Deoxyribonuclease I; Dimerization; DNA; DNA Footprinting; Enhancer Elements, Genetic; Enzyme Induction; Gene Expression Regulation, Enzymologic; Humans; Mice; Mifepristone; Mixed Function Oxygenases; Molecular Sequence Data; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Steroid; Retinoic Acid Receptor alpha; Rifampin; Sequence Homology, Nucleic Acid; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Xenobiotics | 1999 |
Conservation of signaling pathways of xenobiotic-sensing orphan nuclear receptors, chicken xenobiotic receptor, constitutive androstane receptor, and pregnane X receptor, from birds to humans.
Topics: Animals; Avian Proteins; beta-Naphthoflavone; Cell Line; Chickens; Clotrimazole; Colforsin; Constitutive Androstane Receptor; Cyclic AMP; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Inhibitors; Gene Expression Regulation; Genes, Reporter; Glutethimide; Growth Inhibitors; Hormone Antagonists; Humans; Metyrapone; Mifepristone; Okadaic Acid; Pregnane X Receptor; Pregnenolone Carbonitrile; Protein Binding; Pyridines; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Recombinant Fusion Proteins; Rifampin; Signal Transduction; Trans-Activators; Transcription Factors | 2001 |
A cell-based reporter gene assay for determining induction of CYP3A4 in a high-volume system.
Topics: Base Sequence; Blotting, Northern; Cell Line, Transformed; Cell Survival; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA Primers; Enzyme Induction; Genes, Reporter; Hepatocytes; Humans; Liver; Lovastatin; Luciferases; Mifepristone; Mixed Function Oxygenases; Omeprazole; Polychlorinated Dibenzodioxins; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Rifampin; RNA, Messenger; Transcription, Genetic; Transfection | 2002 |
Molecular basis of rifampicin-induced inhibition of anti-CD95-induced apoptosis of peripheral blood T lymphocytes: the role of CD95 ligand and FLIPs.
Topics: Adult; Antibiotics, Antitubercular; Antibodies; Apoptosis; Carrier Proteins; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase 3; Caspase 8; Caspase 9; Caspases; Fas Ligand Protein; fas Receptor; Hormone Antagonists; Humans; Intracellular Signaling Peptides and Proteins; Membrane Glycoproteins; Mifepristone; Rifampin; T-Lymphocytes | 2003 |
Rifampicin and dexamethasone have similar effects on macrophage phagocytosis of zymosan, but differ in their effects on nitrite and TNF-alpha production.
Topics: Adjuvants, Immunologic; Animals; Cells, Cultured; Dexamethasone; Dose-Response Relationship, Drug; Immunity, Innate; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Mifepristone; Nitric Oxide; Phagocytosis; Rifampin; Spleen; Tumor Necrosis Factor-alpha; Zymosan | 2003 |
Expression and induction of CYP3As in human fetal hepatocytes.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Enzyme Inhibitors; Fetus; Hepatocytes; Humans; Insecta; Microsomes; Mifepristone; Phenobarbital; Receptors, Glucocorticoid; Rifampin; RNA, Messenger; Tretinoin | 2004 |
A simultaneous assessment of CYP3A4 metabolism and induction in the DPX-2 cell line.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Chromans; Clotrimazole; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Dimethyl Sulfoxide; Enhancer Elements, Genetic; Enzyme Induction; Genes, Reporter; Genes, Synthetic; Humans; Ketoconazole; Liver Neoplasms; Lovastatin; Luciferases; Mifepristone; Neoplasm Proteins; Nifedipine; Omeprazole; Paclitaxel; Phenytoin; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Recombinant Fusion Proteins; Rifampin; Thiazolidinediones; Transcription, Genetic; Troglitazone; Troleandomycin | 2005 |
Use of cryopreserved transiently transfected cells in high-throughput pregnane X receptor transactivation assay.
Topics: Biological Assay; Caco-2 Cells; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Membrane Permeability; Cryopreservation; Drug-Related Side Effects and Adverse Reactions; Humans; Liver Neoplasms; Mifepristone; Pharmaceutical Preparations; Pregnane X Receptor; Receptors, Steroid; Reproducibility of Results; Rifampin; Sulfinpyrazone; Transcriptional Activation; Transfection | 2007 |
Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3.
Topics: Animals; CHO Cells; Chromans; Clotrimazole; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Drug Interactions; Estradiol; Estrone; Humans; Kinetics; Ligands; Liver-Specific Organic Anion Transporter 1; Mifepristone; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Paclitaxel; Pregnane X Receptor; Receptors, Steroid; Rifampin; Solute Carrier Organic Anion Transporter Family Member 1B3; Thiazolidinediones; Transfection; Troglitazone; Xenobiotics | 2008 |
Lower expression of HNF4α and PGC1α might impair rifampicin-mediated CYP3A4 induction under conditions where PXR is overexpressed in human fetal liver cells.
Topics: Clotrimazole; CREB-Binding Protein; Cytochrome P-450 CYP3A; Dexamethasone; Down-Regulation; Enzyme Induction; Genes, Reporter; Heat-Shock Proteins; Hep G2 Cells; Hepatocyte Nuclear Factor 4; Humans; Liver; Mifepristone; Nuclear Receptor Coactivator 1; p300-CBP Transcription Factors; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Pregnane X Receptor; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Receptors, Steroid; Retinoid X Receptor alpha; Reverse Transcriptase Polymerase Chain Reaction; Rifampin; RNA, Messenger; Transcription Factors; Transfection; Up-Regulation | 2012 |