Compounds > mifepristone
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mifepristone and pd 98059

mifepristone has been researched along with pd 98059 in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.14)18.2507
2000's10 (71.43)29.6817
2010's3 (21.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Fernandes, D; Guida, E; Harris, T; Koutsoubos, V; Stewart, AG; Vadiveloo, P; Wilson, JW1
Lu, J; Xia, B1
Charreau, EH; Coso, OA; Elizalde, PV; Kornblihtt, AR; Labriola, L; Pecci, A; Proietti, CJ; Salatino, M1
Leppla, SH; Moayeri, M; Simons, SS; Sternberg, EM; Tonelli, LH; Webster, JI1
Acosta-Martínez, M; Etgen, AM; Gonzalez-Flores, O1
Derkash, N; Fini, MA; Roberts, LE; Wright, RM1
Baldacci, C; Caruso, A; Flamini, MI; Fu, XD; Garibaldi, S; Genazzani, AR; Giretti, MS; Mannella, P; Sanchez, AM; Simoncini, T1
Chan, TF; Chen, YH; Chuang, CY; Hsu, SC; Lee, JN; Tsai, EM1
Beyer, C; Etgen, AM; Garcia-Juárez, M; Gómora-Arrati, P; González-Flores, O; Komisaruk, BK; Lima-Hernández, FJ; Macias-Jimenez, A1
Chen, Y; Feng, C; Xiao, L1
Chen, Y; Huang, L; Wang, Y; Zhou, F; Zhuang, Y1
Chen, LC; Hsu, SP; Huo, YN; Kuo, CT; Lee, WS; Wen, HC; Yang, HC1

Other Studies

14 other study(ies) available for mifepristone and pd 98059

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Glucocorticoids inhibit proliferation, cyclin D1 expression, and retinoblastoma protein phosphorylation, but not activity of the extracellular-regulated kinases in human cultured airway smooth muscle.
    American journal of respiratory cell and molecular biology, 1999, Volume: 21, Issue:1

    Topics: Androstadienes; Bronchi; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Cell Division; Cells, Cultured; Cyclin D1; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Fluticasone; Glucocorticoids; Humans; Inhibitory Concentration 50; MAP Kinase Kinase 1; Mifepristone; Mitogen-Activated Protein Kinase Kinases; Muscle, Smooth; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Retinoblastoma Protein; Thrombin

1999
[Rapid inhibition of extracellular signal-regulated kinase 1/2 in a human ovarian cancer cell line by dexamethasone].
    Ai zheng = Aizheng = Chinese journal of cancer, 2002, Volume: 21, Issue:8

    Topics: Antineoplastic Agents, Hormonal; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Female; Flavonoids; Humans; Mifepristone; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Ovarian Neoplasms; Time Factors; Tumor Cells, Cultured

2002
Heregulin induces transcriptional activation of the progesterone receptor by a mechanism that requires functional ErbB-2 and mitogen-activated protein kinase activation in breast cancer cells.
    Molecular and cellular biology, 2003, Volume: 23, Issue:3

    Topics: Animals; Breast Neoplasms; Cell Division; Cell Nucleus; Enzyme Inhibitors; Female; Flavonoids; Genes, erbB-2; Hormone Antagonists; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mifepristone; Mitogen-Activated Protein Kinases; Neuregulin-1; Phosphorylation; Receptor, ErbB-2; Receptors, Progesterone; RNA, Messenger; RNA, Neoplasm; Transcriptional Activation; Tumor Cells, Cultured

2003
Anthrax lethal factor represses glucocorticoid and progesterone receptor activity.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, May-13, Volume: 100, Issue:10

    Topics: Animals; Antigens, Bacterial; Bacillus anthracis; Bacterial Toxins; Chlorocebus aethiops; COS Cells; Dexamethasone; Enzyme Inhibitors; Female; Flavonoids; Gene Expression Regulation; Kinetics; Male; Mice; Mice, Inbred BALB C; Mifepristone; Mitogen-Activated Protein Kinases; Receptors, Glucocorticoid; Receptors, Progesterone; Recombinant Proteins; Transfection

2003
The role of progestin receptors and the mitogen-activated protein kinase pathway in delta opioid receptor facilitation of female reproductive behaviors.
    Hormones and behavior, 2006, Volume: 49, Issue:4

    Topics: Animals; Enkephalin, D-Penicillamine (2,5)-; Enzyme Inhibitors; Female; Flavonoids; Hormone Antagonists; Injections, Intraventricular; Male; Mifepristone; Mitogen-Activated Protein Kinases; Neurotransmitter Agents; Phosphorylation; Posture; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Progesterone; Second Messenger Systems; Sexual Behavior, Animal

2006
PD98059 enhanced insulin, cytokine, and growth factor activation of xanthine oxidoreductase in epithelial cells involves STAT3 and the glucocorticoid receptor.
    Journal of cellular biochemistry, 2007, Aug-15, Volume: 101, Issue:6

    Topics: Animals; Cell Line; Cytokines; Dexamethasone; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Genes, Reporter; Glucocorticoids; Hormone Antagonists; Humans; Insulin; MAP Kinase Kinase Kinases; Mice; Mifepristone; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; STAT3 Transcription Factor; Xanthine Dehydrogenase

2007
Drospirenone increases endothelial nitric oxide synthesis via a combined action on progesterone and mineralocorticoid receptors.
    Human reproduction (Oxford, England), 2007, Volume: 22, Issue:8

    Topics: Aldosterone; Androstadienes; Androstenes; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Estradiol; Flavonoids; Humans; Medroxyprogesterone Acetate; Mifepristone; Nitric Oxide; Nitric Oxide Synthase Type III; Progesterone; Receptors, Mineralocorticoid; Receptors, Progesterone; Signal Transduction; Time Factors; Wortmannin

2007
Mifepristone attenuates human chorionic gonadotropin-induced extracellular signal-regulated kinase 1/2 phosphorylation, cyclooxygenase-2, and prostaglandin E2 production in human granulosa luteal cells.
    Fertility and sterility, 2008, Volume: 89, Issue:5 Suppl

    Topics: Adult; Cells, Cultured; Chorionic Gonadotropin; Cyclooxygenase 2; Dinoprostone; Down-Regulation; Drug Interactions; Enzyme Inhibitors; Female; Flavonoids; Hormone Antagonists; Humans; JNK Mitogen-Activated Protein Kinases; Luteal Cells; Mifepristone; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phosphorylation; RNA, Messenger

2008
Antagonists of the protein kinase A and mitogen-activated protein kinase systems and of the progestin receptor block the ability of vaginocervical/flank-perineal stimulation to induce female rat sexual behaviour.
    Journal of neuroendocrinology, 2008, Volume: 20, Issue:12

    Topics: Animals; Cervix Uteri; Contraceptives, Postcoital, Synthetic; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Estradiol; Female; Flavonoids; Male; MAP Kinase Signaling System; Mifepristone; Mitogen-Activated Protein Kinases; Ovariectomy; Perineum; Posture; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Progesterone; Sexual Behavior, Animal; Thionucleotides; Vagina

2008
Glucocorticoid rapidly enhances NMDA-evoked neurotoxicity by attenuating the NR2A-containing NMDA receptor-mediated ERK1/2 activation.
    Molecular endocrinology (Baltimore, Md.), 2010, Volume: 24, Issue:3

    Topics: Animals; Blotting, Western; Calcium; Cells, Cultured; Enzyme Inhibitors; Flavonoids; Glucocorticoids; Hippocampus; Imidazoles; Mifepristone; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; N-Methylaspartate; Neurons; p38 Mitogen-Activated Protein Kinases; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

2010
Mifepristone increases the cytotoxicity of uterine natural killer cells by acting as a glucocorticoid antagonist via ERK activation.
    PloS one, 2012, Volume: 7, Issue:5

    Topics: Adult; Blotting, Western; Butadienes; Cell Survival; Cells, Cultured; Decidua; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Female; Flavonoids; Glucocorticoids; Hormone Antagonists; Humans; Hydrocortisone; K562 Cells; Killer Cells, Natural; Mifepristone; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Perforin; Phosphorylation; Pregnancy; Up-Regulation; Young Adult

2012
Progesterone receptor-NFκB complex formation is required for progesterone-induced NFκB nuclear translocation and binding onto the p53 promoter.
    Endocrinology, 2015, Volume: 156, Issue:1

    Topics: Active Transport, Cell Nucleus; Butadienes; Cells, Cultured; Endothelial Cells; Enzyme Inhibitors; Estrenes; Flavonoids; Furans; Gene Expression Regulation; Hormone Antagonists; Humans; Mifepristone; NF-kappa B; Nitriles; Progesterone; Promoter Regions, Genetic; Protein Binding; Receptors, Progesterone; Sulfones; Tumor Suppressor Protein p53

2015